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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-rehospitalization_research.pdf
    November 01, 2007 - Biostatistics, and Medicine, University of California, San Francisco, San Francisco, CA. 3 Meyers Primary … Measures Receipt of β-Blockers The primary exposure of interest was time-dependent receipt of … Rehospitalization for Heart Failure The primary outcome of interest was rehospitalization for heart … The primary comparisons of interest were metoprolol tartrate vs. atenolol and carvedilol vs. … Unstable Angina: (a) 1 primary dx of 411.1, 411.8, 411.9 or 30 (b) 1 primary dx of 414.x (CAD)
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_overview.pdf
    June 24, 2014 - . § The investigators “found no benefit of stenting with respect to the rate of the composite primary
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-2.xlsx
    September 30, 2015 - Fair Neumann, 2020 RCT (open-label, crossover) Duration: 6 months University-affiliated outpatient primary … ; f/u = follow-up; LTFU = long-term follow-up; NR = nor reported; NRS = numeric rating scale; PCP = primary … sample); 38,716 (matched sample) Visit counts for physical therapy, pain clinics, chiropractic care, primary … diagnosis codes Enrolled: 77,697 Analyzed: 77,697 Loss to followup: NA Sex, income, geographic region, primary
  4. effectivehealthcare.ahrq.gov/sites/default/files/therapies-for-autism-spectrum-disorder-2-9-2010.pdf
    January 01, 2010 - Many therapies are not covered by insurance, and a primary reason for insurance denial from private … The delivery and organization of care for ASD is very fragmented, with pieces scattered about in the primaryPrimary outcomes. … Abstract review forms will contain questions about primary exclusion/inclusion criteria. … systematically and summarizing them, we will capture key earlier literature without including it as primary
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism_research-protocol.pdf
    December 09, 2009 - Many therapies are not covered by insurance, and a primary reason for insurance denial from private … The delivery and organization of care for ASD is very fragmented, with pieces scattered about in the primaryPrimary outcomes. … Abstract review forms will contain questions about primary exclusion/inclusion criteria. … systematically and summarizing them, we will capture key earlier literature without including it as primary
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-treatment_research-protocol.pdf
    November 08, 2011 - Systematic reviews will be used as primary sources of evidence if they are considered to be of good … Search Strategies for Identification of Relevant Studies To Answer the Key Questions To identify primary … criteria; population and clinical characteristics (including sex, age, body mass index, ethnicity, primary … Where possible, these data will be the primary focus. … indirect comparisons will be used to support direct comparisons when they exist and will be used as the primary
  7. effectivehealthcare.ahrq.gov/sites/default/files/sadwin.pdf
    January 01, 2011 - Slide 8 Example #1 Lifestyle Change, Primary & Secondary Prevention Slide 9
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-pregnancy-postpartum_research-protocol.pdf
    March 29, 2013 - Using a second drug to augment the effects of the primary drug and comparing this treatment with monotherapy … The combination include: (a) Using a second drug to augment the effects of the primary drug and … Medical provider characteristics (primary care physician, obstetrician, psychiatrist, nurse, midwife … Chronic illness • Infant health system visits (e.g., well baby visits) o Health care utilization (primary … characteristics (dose, duration, and cointerventions); comparisons; medical provider characteristics (primary
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nursing-home-safety_research-protocol.pdf
    July 22, 2015 - An overview of the existing literature and an assessment of gaps in systematic reviews and primary research … To search the primary literature for areas not covered by existing reviews and to update the reviews … information from our Key Informants; we will use systematic reviews, narrative reviews, meta-analyses, and primary … overview tables of the available systematic reviews included, as well as tables of the additional primary … Acute Care Transfers (INTERACT) quality improvement program: an overview for medical directors and primary
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_research-protocol.pdf
    April 01, 2013 - Current practice is to use tumor grade as the primary prognostic variable in patients with clinically … less aggressive, and Gleason 6 or lower tumors are considered potentially indolent.13 Although the primary … • Head-to-head RCTs must be adequately powered to compare primary treatments for localized prostate … Hormonal therapy as primary therapy, adjuvant, or neoadjuvant to other therapies h. … Outcomes • The primary outcome is overall mortality or survival.
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/making-healthcare-safer-IV.pdf
    August 04, 2023 - about practices that can improve patient safety across the healthcare system - from hospitals to primary … no recent high quality systematic reviews are identified, we will conduct searches of PubMed for primary … about the effectiveness of infection surveillance PSPs for MRSA, CRE, C.auris, and C.difficile, the primary … If we identify a recent eligible systematic review, the primary reviewer will use the criteria developed
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0367_11-08-2010.pdf
    January 01, 2010 - treatment, including different providers/access points (e.g., ob/gyn, pediatrician, community based, primary
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0129_07-13-2009.pdf
    January 01, 2009 - literature examining various factors, interventions, and practices that include cesarean rate as a primary
  14. effectivehealthcare.ahrq.gov/sites/default/files/diabetic-neuropathy-disposition-170707.pdf
    March 24, 2017 - back further; if we did not find systematic reviews within this time frame, we did a full search for primary … Suggest removing “of Individual Studies”, as the following subheadings “Systematic Reviews” and “Primary … for questions where we did not identify high quality relevant systematic reviews, we searched for primary … to do this for pregabalin, since later studies were not focused on pregabalin effectiveness as a primary … One trial had no defined primary endpoint and no placebo response.
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetic-neuropathy-disposition-170707.pdf
    March 24, 2017 - back further; if we did not find systematic reviews within this time frame, we did a full search for primary … Suggest removing “of Individual Studies”, as the following subheadings “Systematic Reviews” and “Primary … for questions where we did not identify high quality relevant systematic reviews, we searched for primary … to do this for pregabalin, since later studies were not focused on pregabalin effectiveness as a primary … One trial had no defined primary endpoint and no placebo response.
  16. effectivehealthcare.ahrq.gov/sites/default/files/outcome-definition-and-measurement-chapter-6.pptx
    January 01, 2013 - This presentation will: Propose primary and secondary outcomes that directly correspond to research questions … effects of treatment on these outcomes may be substantially shorter than for the clinical outcome(s) of primary … Design and Analysis (2 of 2) Study Period and Length of Followup To a large extent, the form of the primary … Summary Checklist (1 of 3) Guidance Key Considerations Propose primary and secondary outcomes that … questions The followup period should be sufficient to observe hypothesized effects of treatment on primary
  17. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
    April 01, 2007 - balancing such factors as their importance for the integrity of the registry and for the analysis of primary … Data sources can be classified as primary or secondary. … Primary data are collected for direct purposes of the registry. … other than the registry, and they may not be uniformly structured or validated with the same rigor as primary … The report includes a clear statement of any conclusions drawn from the analysis of the registry’s primary
  18. effectivehealthcare.ahrq.gov/sites/default/files/01_arthritis_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - that tofacitinib might also improve health outcomes through earlier diagnosis and treatment in the primary … patients treated with PRP injections. 28 In a retrospective analysis, consecutive patients with primary … Tofacitinib could also increase access to care if primary care physicians were comfortable prescribing … tofacitinib; however, one clinical expert stated that this is unlikely because primary care physicians … Injection of platelet-rich plasma in patients with primary and secondary knee osteoarthritis: a
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_executive.pdf
    March 01, 2013 - 1 Comparative Effectiveness Review Number 96 Primary Care Management of Abnormal Uterine Bleeding … For KQ2, we expanded our search of primary literature to include standard drug package inserts, and … We excluded studies of women with infertility if the primary treatment goal was conception. … Twelve interventions relevant to the primary care setting were identified for this report. … Primary Care Management of Abnormal Uterine Bleeding. Comparative Effectiveness Review No. 96.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
    September 19, 2014 - Opioid prescriptions by U.S. primary care physicians from 1992 to 2001. … Low use of opioid risk reduction strategies in primary care even for high-risk patients with chronic … Substance use disorders in a primary care sample receiving daily opioid therapy. … Opioids for back pain patients: primary care prescribing patterns and use of services. … Effect of an opioid management system on opioid prescribing and unscheduled visits in a large primary

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