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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/monitoring-programs-protocol.pdf
    January 01, 2024 - agencies about PSPs that can improve patient safety across the healthcare system—from hospitals to primary … We will not include systematic reviews as primary data sources, but will use reference lists of all … Data Extraction The primary reviewer will screen titles and abstracts for potential inclusion. … In that case, the title and abstract of each citation will be reviewed by the primary reviewer, and … We will not include systematic reviews as primary data s... Table 1.
  2. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/rt-bone-metatases-final-protocol-amendment.pdf
    August 10, 2022 - metastatic disease, particularly high incidence of metastatic bone disease (MBD) was seen from solid primary … Severe pain and complications that compromise quality of life are the primary symptoms of MBD. … life, reduction in analgesic requirements, and stabilization or enhancement of skeletal function are primary … It involves consideration of primary tumor histology, patient prognosis and life expectancy, existing … We will focus on primary studies and review systematic review (SR) references for relevant studies as
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-use-disorder_research-protocol.pdf
    February 24, 2016 - Although this has increased access to buprenorphine in primary care settings, research indicates that … The Technical Brief will focus on implementation of MAT in primary care settings, including rural or … What have published and unpublished studies reported on the use of and effectiveness MAT in primary … What  are  barriers  to  implementation  of  MAT  in  primary  care  settings?   7.   … care settings, implementation strategies, particularly in primary care and rural settings, and will
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/traumatic-brain-injury-rehabilitation_research-protocol.pdf
    October 25, 2010 - 275,000 were hospitalized, and 50,000 died from their injuries. 2 Additional TBIs are treated in primary … Two investigators will act as primary and secondary abstractors/evaluators for their assigned studies … The primary abstractor/evaluator will abstract relevant data from studies meeting inclusion criteria … Assessment of Risk of Bias of Individual Studies The primary and secondary abstractor/evaluator … A sample initial search strategy for primary studies appears below: Appendix Table A-1.
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_disposition-comments.pdf
    November 27, 2012 - We stand by these as our primary outcomes. Other outcomes are included. … Patients were recruited from primary sleep centers. … Few studies enrolled patients from primary care clinics. … A large selection bias versus primary care patients is possible. … primary care providers.
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs_research-protocol.pdf
    December 16, 2011 - with similar symptoms (e.g. neuropathies, pain syndromes). 5 RLS is believed to be idiopathic or primary … in primary care. … However, in primary care, the standard criteria may be less consistently applied. …  Studies involving participants from primary or specialty care settings. … Algorithms for the diagnosis and treatment of restless legs syndrome in primary care.
  7. effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - The visit concludes with patients being referred to or reconnected with their primary care providers … Experts noted the ability of this intervention to alleviate some demand on primary care physicians … Finally, patients are referred to or reconnected with primary care providers.22 The postdischarge … care followup (PDC, 3.8 days; urgent care, 5.0 days; primary care, 6.2 days; p=0.04 between groups … care, p=0.42); there was 7 similarly no difference between PDC and primary care followup in
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-reporting-bias_methods.pdf
    November 01, 2013 - outcome omission, upgrading from secondary to primary outcome, new primary outcome introduction, underreporting … Primary and secondary endpoints, primary endpoint results, statistical analysis, and statistical significance … outcome in the publications of 8 of 12 trials (new primary outcome, no distinction between primary … Registry Name of Primary Registry Primary Registry ID Unique ID number assigned by the Primary Registry … the Primary Registry.
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_executive.pdf
    September 01, 2014 - For comparative questions, we synthesized the evidence from the primary studies themselves. … Summary results for primary preoperative rectal T staging Test Characteristics MRI vs. … We identified seven primary comparative studies that addressed this question. … We identified 16 primary comparative studies that addressed this question. … We identified nine primary comparative studies of interim restaging.
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-appendix-c-prepub-final.xlsx
    January 01, 2025 - or secondary tissue of origin prediction: OverC-Model 1 primary: 83.2% (95% CI, 78.7% to 87.1%); primary … or secondary: 91.7% (95% CI, 88.2% to 94.5%) OverC-Model 2 primary: 79.4% (95% CI, 74.9% to 83.5%); … 4.6 Were biases in primary studies minimal or addressed in the synthesis? … 1.3 Reason 2.1 Did any of the primary academic researchers have important conflicts of interest? … 1.3 Reason 2.1 Did any of the primary academic researchers have important conflicts of interest?
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-final-app-c.xlsx
    January 01, 2025 - or secondary tissue of origin prediction: OverC-Model 1 primary: 83.2% (95% CI, 78.7% to 87.1%); primary … or secondary: 91.7% (95% CI, 88.2% to 94.5%) OverC-Model 2 primary: 79.4% (95% CI, 74.9% to 83.5%); … 4.6 Were biases in primary studies minimal or addressed in the synthesis? … 1.3 Reason 2.1 Did any of the primary academic researchers have important conflicts of interest? … 1.3 Reason 2.1 Did any of the primary academic researchers have important conflicts of interest?
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-staging_research-protocol.pdf
    May 20, 2013 - The second time point applies only to patients who, on the basis of their primary staging, were treated … For stage I, II, and III disease, surgical resection is the primary treatment. … After completion of primary treatment, patients usually enter a routine surveillance program intended … They allow imaging of the primary tumor (including the depth of invasion into the bowel wall) and its … separately—primary versus recurrent disease and primary staging versus interim restaging.
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-addendum-app.xlsx
    May 29, 2025 - Comparator Prior and Concurrent Treatments Site of Bone Metastases Characteristics of Bone Metastases Primary … Health, % Other Study Participant Characteristics Outcome Measures Duration of Follow-Up Results - Primary … vertebral body permitted; Radioresistant cancers permitted; Systemic/visceral metastases/uncontrolled primary
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_surveillance.pdf
    June 01, 2012 - The HR for Primary end point or death was 0.81 with 95% CI= 0.42, 1.56 8 1 Signal 3. … Primary stenting for atherosclerotic renal artery stenosis. [Review] [35 refs]. … medical treatment (antihypertensive Two years Primary: 20% or greater decrease in creatinine … end point or death, n (%): 22 (30) vs. 15 (24); HR= 0.81; 95% CI= 0.42, 1.56 Primary end point … medical treatment Two years Primary: 20% or greater decrease in Medical vs.
  15. effectivehealthcare.ahrq.gov/sites/default/files/implementation-package-unhealthy-alcohol-use-final.pdf
    September 01, 2018 - Screening, Behavioral Counseling, and Referral in Primary Care to Reduce Alcohol Misuse. … Behavioral counseling in primary care is the appropriate intervention. … Primary References: 1. National Institute on Alcohol Abuse and Alcoholism. … Primary care validation of a single- question alcohol screening test. … E-8 PRIMARY REFERENCES: 1.
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_research-protocol.pdf
    November 24, 2014 - initially present to a psychiatric clinic are, in general, similar to those who seek treatment in primary … Outcomes following an initial, evidence-based treatment with antidepressants in primary care settings … At the same time, primary care physicians appreciate that other potentially effective interventions … This review will focus on two key issues facing primary care physicians: 1. … Pharmacotherapy remains the primary intervention for MDD patients in primary care.
  17. - (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease-future_research.pdf
    July 01, 2016 - Mucosal healing is not ready to be the primary endpoint. … Mucosal healing should be a primary endpoint. american gastroenterological association. … Mucosal healing is not ready to be the primary endpoint. … Mucosal healing should be a primary endpoint. american gastroenterological association. … McMaster quality assessment scale of harms (McHarm) for primary studies. 16.
  18. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-outcome-measure-harmonization-depression.pdf
    November 01, 2020 - The primary objective of this project is to demonstrate the feasibility and value of capturing the harmonized … information about the practical challenges, value, and burden of using the harmonized measures in the primary … , and a final letter of approval was obtained on March 6, 2020. 8 Key Findings The primary … For example, patients may present to the emergency room rather than the primary care practice in these … Monitoring Suicidal Patients in Primary Care Using Electronic Health Records.
  19. 13-MDM347013 30..38 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/outcomes-testing-evaluation_research.pdf
    January 01, 2009 - have to define the primary and secondary outcome measures in randomized or other trials of testing. … We also show how these additional effects can influence the primary clinical outcome of testing via … The primary purpose of health care is to restore or preserve health, so survival, disability, activity … Existing testing trials and studies do not always have a health outcome as the primary outcome measure … These changes may amplify or attenuate the intended effect on the primary clinical outcome.
  20. 13-MDM347013 30..38 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/whitepaper4-bossuyt02262010-2.pdf
    January 01, 2009 - have to define the primary and secondary outcome measures in randomized or other trials of testing. … We also show how these additional effects can influence the primary clinical outcome of testing via … The primary purpose of health care is to restore or preserve health, so survival, disability, activity … Existing testing trials and studies do not always have a health outcome as the primary outcome measure … These changes may amplify or attenuate the intended effect on the primary clinical outcome.

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