- 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/home-based-care_research-protocol.pdf
November 19, 2014 - Physical, psychological, and cognitive 
• Mortality 
• Morbidities 
o Examples:  falls, incontinence, pressure … ulcers, depression, delirium, 
dementia with behavioral problems, pain 
• Patient Safety 
o Errors
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research.pdf
February 01, 2014 - Protocol for Quantitative Assessment of Benefit and Harm analysis of Aspirin for primary prevention
Methods Research Report 
 
Evaluation of the Benefits and Harms of Aspirin for 
Primary Prevention of Cardiovascular Events: A 
Comparison of Quantitative Approaches 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management-1_research.pdf
July 01, 2012 - Improving Medication Safety in High Risk Medicare Beneficiaries Toolkit
 
Improving Medication Safety 
in High Risk Medicare Beneficiaries Toolkit 
Daniel R. Touchette, Pharm.D., M.A. 
JoAnn Stubbings, R.Ph., M.H.C.A. 
Glen Schumock, Pharm.D., M.B.A. 
Number 38 
July 2012 
ii 
The DEcIDE (Developing Evidence … 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-249-malnutrition-disposition-comments_0_0.pdf
October 13, 2021 - implemented by CMS, although there is 
considerable focus on some of the sequelae of 
malnutrition such as pressure … ulcers, infections, 
30-day readmissions, and mortality, no measure 
considering the role of nutrition
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nursing-staff-shortages-rapid-research.pdf
April 01, 2025 - to zero, and hospital-
 
 
16 Making Healthcare Safer IV – Nursing Staff Shortages 
acquired pressure … ulcers decreased from 26 before the staffing change to 22 after the 
staffing change (no statistics
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/implementation-package-unhealthy-alcohol-use-final.pdf
September 01, 2018 - Implementing Evidence-Based Screening and Counseling for Unhealthy Alcohol-Use With Epic-Based Electronic Health Record Tools: A Guide for Clinics and Health Systems Developed as Part of a Pilot Dissemination Project
Implementing Evidence-Based Screening and 
Counseling for Unhealthy Alcohol Use With Epic-
Based Elec… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_executive.pdf
January 27, 2012 - 1
Comparative Effectiveness Review 
Number 134
Pharmacotherapy for Adults With Alcohol-Use 
Disorders in Outpatient Settings
Executive Summary
Background
Alcohol misuse, or unhealthful alcohol 
use, which includes the full spectrum 
from drinking above recommended 
limits (i.e., risky/hazardous drinking) to 
alcoho… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-urinary-retention_research.pdf
September 01, 2014 - Chronic Urinary 
Retention: 
Comparative 
Effectiveness and 
Harms of Treatments
Comparative Effectiveness Review
Number 140
Comparative Effectiveness Review 
Number 140 
Chronic Urinary Retention: Comparative Effectiveness 
and Harms of Treatments 
Prepared for: 
Agency for Healthcare Research and Quality 
U.S. D… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/grades-predictive-values_white-paper-2015.pdf
January 01, 2015 - Research White Paper 
 
 
 
 
 
 
 
 
 
 
 
 
Comparison of Effects as Evidence Evolves From 
Single Trials to High-Quality Bodies of Evidence 
 
  
 
Research White Paper 
 
 
Comparison of Effects as Evidence Evolves From 
Single Trials to High-Quality Bodies of Evidence  
 
 
Prepared for:  
Agency for Healthc… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd_executive.pdf
September 01, 2011 - Layout 1
Background
Gastroesophageal reflux disease (GERD) is
one of the most common health conditions
affecting Americans. A study of an
employed population in the United States
estimated that more than 11,000 of 267,000
employees (4 percent) suffered from
GERD, contributing an average
incremental cost to the emplo… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-refinement_methods.pdf
January 01, 2013 - Pressure 
Ulcer Treatment Strategies: A Comparative 
Effectiveness Review.
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disabilities-quality-improvement-outcomes_executive.pdf
October 01, 2012 - including:
8
• Preventive dental care
• Preventive medical care 
• Urinary tract infections
• Pressure … ulcers
• Diabetes and diabetic complications
• Pneumonia
• Asthma
• Gastroenteritis
• Hypertension
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-nursing-home-characteristics_research-protocol.pdf
November 03, 2011 - Functional decline 
○ Cognitive decline 
○ Symptoms of depression 
○ Falls 
○ Morbidities (e.g., pressure … ulcers) 
○ Hospitalization 
○ Mortality 
○ Sleep quality 
 
Psychosocial outcomes for people with
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-3-nonopioid-pharm-chronic-pain.pdf
July 01, 2022 - Systematic Review on Nonopioid Pharmacologic Treatments for Chronic Pain: Surveillance Report 3
Systematic Review on Nonopioid 
Pharmacologic Treatments for Chronic 
Pain: Surveillance Report 3 
Literature Update Period: January 2022 through April 1, 2022 
Background and Purpose 
This is the third surveillance repor… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cultural-competence_research-protocol.pdf
July 09, 2014 - secondary to the disability such as urinary tract infections, asthma, obesity, 
hypertension, and pressure … ulcers.5 
As the overlapping circles in Figure1 suggest, there are also interventions 
encompassed
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1412.pdf
December 01, 2014 - #05 DEPRESSION
AHRQ Healthcare Horizon Scanning System – Potential 
High-Impact Interventions Report 
 
Priority Area 05: Depression and Other Mental Health 
Disorders  
 
Prepared for:  
Agency for Healthcare Research and Quality 
U.S. Department of Health and Human Services  
540 Gaither Road 
Rockville, MD… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1406.pdf
June 01, 2014 - #05 DEPRESSION
AHRQ Healthcare Horizon Scanning System – Potential 
High-Impact Interventions Report 
 
Priority Area 05: Depression and Other Mental Health 
Disorders  
 
Prepared for:  
Agency for Healthcare Research and Quality 
U.S. Department of Health and Human Services  
540 Gaither Road 
Rockville, MD… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/child-growth-development-outcomes-protocol-amended.pdf
November 18, 2024 - Dietary Total Fat Intake and Dietary Polyunsaturated Fatty Acid Intake and Child Growth and Development Outcomes: A Systematic Review
 
 
 
Evidence-based Practice Center Systematic Review Protocol 
 
Project Title: Dietary Total Fat Intake and Dietary Polyunsaturated Fatty Acid 
Intake and Child Growth and Develop… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/child-growth-development-outcomes-protocol.pdf
August 19, 2024 - Dietary Total Fat Intake and Dietary Polyunsaturated Fatty Acid Intake and Child Growth and Development Outcomes: A Systematic Review
 
 
 
Evidence-based Practice Center Systematic Review Protocol 
 
Project Title: Dietary Total Fat Intake and Dietary Polyunsaturated Fatty Acid 
Intake and Child Growth and Develop… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/functional-limitations-horizon-scan-high-impact-1306.pdf
June 01, 2013 - several experts thought that besides providing psychological benefits, 
this intervention might improve pressure … ulcer incidence as well.