- 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/s50.pdf
October 01, 2007 - Practice-Based Evidence for Clinical Practice
Improvement in Long-term Care
The National Pressure Ulcer … ulcers. … No resident started with a pressure ulcer, but
29% of residents developed one by the end of the 12-week … ulcers decreased up to 65%. … The National Pressure Ulcer
Long-Term Care Study: pressure ulcer development in long-term care
residents
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment_research-protocol.pdf
September 13, 2012 - high relevance to morphologically similar ulcers found in patients 
with diabetes, arterial disease, pressure … ulcers, postsurgical chronic wound ulcers, and ulcers 
consequent to internal diseases. … ankle brachial index less than 0.6 
or a toe brachial index less than 0.5 or other clinical criteria), pressure … ulcers, postsurgical 
ulcers, and neuropathic ulcers … ulcers, post-surgical 
ulcers, and neuropathic ulcers.
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_executive.pdf
January 01, 2014 - 1
Comparative Effectiveness Review 
Number 127
Chronic Venous Ulcers: A Comparative 
Effectiveness Review of Treatment Modalities
Executive Summary
Background
Venous leg ulcers are extremely common 
in the United States. They affect between 
500,000 and 2 million people annually, and 
are responsible for over 50 pe… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_disposition-comments.pdf
January 27, 2014 - Disposition of Comments Report for Chronic Venous Ulcers: A Comparative Effectiveness Review of Treatment Modalities
  
 
 
Comparative Effectiveness Review Disposition of Comments Report 
 
Research Review Title: Chronic Venous Ulcers: A Comparative Effectiveness Review of 
Treatment Modalities 
 
Draft review av… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0004_03-11-2008.pdf
January 01, 2008 - Effective Health Care
Topic Numbers:     0060  
Document Completion Date:  1-12-10 
1 
 
 
 
Results of Topic Selection Process & Next Steps 
 
 Noninvasive positive pressure ventilation (NPPV) for acute respiratory failure will go forward for 
refinement as a systematic review.  The scope of this topic, includ… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
October 01, 2011 - Layout 1
Background
Osteoarthritis is a chronic condition
involving degeneration of cartilage within
the joints. It is the most common form of
arthritis and is associated with pain,
substantial disability, and reduced quality
of life.1 Surveys indicate that 5 to 17
percent of United States (U.S.) adults have
symptom… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nppv-respiratory-failure_research-protocol.pdf
April 21, 2011 - Evidence-based Practice Center Systematic Review Protocol
 
 
Source: www.effectivehealthcare.ahrq.gov 
Published Online: April 21, 2011  Page 1 
Evidence-based Practice Center Systematic Review Protocol 
 
Project Title: Noninvasive Positive-Pressure Ventilation (NPPV) for Acute Respiratory 
Failure  
 
I. B… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_executive.pdf
July 01, 2012 - 1
Comparative Effectiveness Review 
Number 68
Noninvasive Positive-Pressure 
Ventilation (NPPV) for Acute  
Respiratory Failure 
Executive Summary
Background
Acute respiratory failure is a life-
threatening condition characterized by 
an inability to maintain normal levels 
of oxygen and/or carbon dioxide gas 
exc… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_executive.pdf
January 01, 2006 - Layout 1
Background
Osteoarthritis is a chronic condition
involving degeneration of cartilage within
the joints.  It is the most common form of
arthritis and is associated with pain,
substantial disability, and reduced quality
of life.  About 6 percent of U.S. adults aged
30 years or older have symptomatic
osteoarthr… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-disposition-120516.pdf
October 01, 2011 - Comparative Effectiveness and Safety of Analgesics for Osteoarthritis—An Update of the 2006 Report.
 
Source: http://www.effectivehealthcare.ahrq.gov/index.cfm/search-for-guides-reviews-and-
reports/?productid=494&pageaction=displayproduct 
Published Online: August 2010 
 
 
 
Comparative Effectiveness Research Re… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/disabilities-quality-improvement-outcomes_research-protocol.pdf
August 03, 2011 - Preventive 
Services Task Force) 
o Urinary tract infections 
o Pressure ulcers 
o Uncontrolled diabetes … 14. 9 and 13 4943   
15. limit 14 to (english language and yr="1990 -Current") 3663   
 
KQ 1b Pressure … ulcer example search 
 
  1. exp Disabled Persons/ 39840   
  2. exp mental disorders diagnosed in … . intellectual disabilit$.mp. 3092   
  9. 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 214730   
10. exp Pressure … Ulcer/ 8794   
11. 9 and 10 120   
 
KQs 2 and 3 Coordinated care example search 
 
  1. exp Disabled
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/wheelchair-service_research-protocol.pdf
July 01, 2010 - Adverse events/harms/safety issues (i.e., pressure sores, injuries, need for repairs, 
need for replacement … , functional and physiologic outcomes, patient satisfaction, use), and 
harms (i.e., development of pressure … sores, deconditioning, weight gain). … a. tilt frame – tilts user backward in seated position to change pressure points and help 
prevent pressure … ulcers; also to improve seating balance 
b. reclining – reclining backrest opens hip angle; for pressure
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetic-neuropathy_research-protocol.pdf
May 09, 2016 - Effectiveness of Treatments for Diabetic Peripheral Neuropathy
 
 
 
 
 
       
 
 
   
  
  
  
  
 
 
  
 
 
 
   
  
 
   
 
 
 
  
    
 
    
      
  
  
Evidence-based Practice Center  Systematic Review Protocol
 
Project Title: Effectiveness of Treatments for  Diabetic Per ipheral Neuropa… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/wheelchair-users-amended-protocol.pdf
June 21, 2019 - ulcers; development of obesity; body mass 
index (BMI); weight; depression; quality of life; time to … Does physical activity reduce the harms of immobility, such as incidence of 
decubitus ulcer, urinary … ulcers; development of obesity; BMI; weight; depression; quality of life; time to 
wheelchair use; … ulcers 
Body composition 
• Weight, BMI, development of obesity, waist 
circumference, % body fat … ulcers None  
Body 
Composition 
Body mass index 
Development of obesity  
Weight  
• Percent (%)
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_consumer.pdf
June 01, 2016 - Treating Infantile Hemangiomas in Children
Treating Infantile 
Hemangiomas in Children
A Review of the Research for Parents and Caregivers
e
Archived: This report is greater than 3 years old. Findings may be used for research purposes, but should not be considered current.
Archived: This 
report is greater 
than 3… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_appendixes.pdf
January 01, 2006 - Comparative Effectiveness Review
118 
Appendix A. Pharmacokinetics, Indications and 
Dosing of Included Drugs 
 
 
 
Drug and Trade 
Name  
(Trade names 
provided only for 
drugs under 
patent.) 
Half-life or other 
relevant 
pharmacokinetic 
feature 
Labeled indications Dosing (oral 
doses) 
Dose adjustments fo… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-safety-practices_research-protocol.pdf
November 09, 2011 - safety problems 
 Preventing ventilator-associated pneumonia – coordinate with AHRQ HAI report 
 Pressure … ulcer prevention 
 Promoting a culture of safety 
 Universal protocol/preoperative checklist (surgical
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-update_research-protocol.pdf
January 15, 2015 - renal-update-2015-150115
 
  
   
 
 
  
 
  
 
 
  
 
 
 
 
 
 
 
  
 
   
 
 
 
   
 
 
   
 
  
Evidence-based Practice Center Systematic Review Protocol 
Project Title: Renal Artery Stenosis Update 
Initial publication date if applicable: 2006, with a 2007 update 
I.  Background and Objectives… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
January 31, 2013 - Source: www.effectivehealthcare.ahrq.gov 
Originally published online: January 31, 2012; Amended January 31, 2013 
Evidence-based Practice Center Systematic Review Protocol 
Project Title: Treatment Strategies for Patients With Peripheral Artery Disease (PAD) 
 
Amendment Date(s):  January 31, 2013 
(Amendment Detai… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/s16.pdf
October 01, 2007 - ORIGINAL ARTICLE
Creating and Synthesizing Evidence With Decision Makers
in Mind
Integrating Evidence From Clinical Trials and Other Study Designs
David Atkins, MD, MPH
Background: Randomized controlled trials (RCTs) remain the ac-
cepted “gold standard” for determining the efficacy of new drugs or
medical procedur…