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www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/075-antibiotic-prophylaxis-summary-table.pdf
April 01, 2025 - Antimicrobial Prophylaxis Recommendations
AHRQ Safety Program for MRSA Prevention:
Targeting SSI … loss
>1500 ml7
Significantly
increased risk of
acute kidney injury2,10
*From initiation of preoperative … Clinical practice guidelines for
antimicrobial prophylaxis in surgery. … Perioperative Antibiotic Prophylaxis:
Surgeons as Antimicrobial Stewards. … Therapy for Surgical Prophylaxis
Antimicrobial Prophylaxis Recommendations for Adults for the Surgeries
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www.ahrq.gov/hai/tools/mrsa-prevention/surgery/antimicrobial-prophylaxis.html
April 01, 2025 - MRSA Prevention Toolkit: Targeting SSI
Antimicrobial Prophylaxis
Previous Page Next Page … Prophylaxis Antimicrobial Prophylaxis is a proven strategy to reduce surgical site infections (SSIs) … Prophylaxis Part 1 – Slides (PPTX, 3 MB) Antimicrobial Prophylaxis Part 1 – Facilitator Guide (DOCX … the recommendations for the duration of preoperative antimicrobial prophylaxis. … antimicrobial prophylaxis.
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www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/076-antimicrobial-prophylaxis-duration-one-pager.docx
April 01, 2025 - Antimicrobial Prophylaxis Duration
Surgical Services … Clinical practice guidelines for antimicrobial prophylaxis in surgery. … Timing of Preoperative Antibiotic Prophylaxis and Surgical Site Infections: TAPAS, an observational cohort … Single- versus multiple-dose antimicrobial prophylaxis for major surgery: a systematic review. … Perioperative antibiotic prophylaxis: surgeons as antimicrobial stewards.
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www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/003-ss-antimicrobial-prophylaxis-part-2-fg.docx
April 01, 2025 - Prophylaxis: Part 2, Beyond the Basics
SAY:
This presentation builds off the Antimicrobial Prophylaxis … This presentation, along with Antimicrobial Prophylaxis Part 1, discusses the key strategy of antimicrobial … several important topics of antimicrobial prophylaxis. … With preoperative allergy evaluation, there was increased use of recommended prophylaxis, meaning cefazolin … In addition to patients receiving optimal antimicrobial prophylaxis, preoperative evaluation by an allergist
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www.ahrq.gov/hai/tools/mrsa-prevention/surgery/key-strategies.html
April 01, 2025 - MRSA and SSI Prevention Phases
The Evidence for MRSA Decolonization
Nasal Decolonization
Use of Preoperative … Chlorhexidine Antisepsis
Decolonization Resources
Antimicrobial Prophylaxis
Hand Hygiene in the … Section: Antimicrobial Prophylaxis Patients undergoing surgery need to have antimicrobial prophylaxis … The recommendations regarding antimicrobial prophylaxis are actually very similar for cardiac, hip and … Antimicrobial Prophylaxis Part 1 Antimicrobial Prophylaxis Part 2: Beyond the Basics Section: Evidence-Based
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www.ahrq.gov/hai/tools/mrsa-prevention/surgery/prevention-phases.html
April 01, 2025 - MRSA and SSI Prevention Phases
The Evidence for MRSA Decolonization
Nasal Decolonization
Use of Preoperative … Chlorhexidine Antisepsis
Decolonization Resources
Antimicrobial Prophylaxis
Hand Hygiene in the … Prophylaxis Hand Hygiene MRSA Surveillance Nasal Decolonization Use of Preoperative Chlorhexidine Antisepsis … Decolonization Resources * Pre-op Phase Antimicrobial Prophylaxis Contact Precautions Optimizing Environmental … Antisepsis Surgery Phase Antimicrobial Prophylaxis Optimizing Environmental Cleaning Glycemic Control
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www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/001-ss-antimicrobial-prophylaxis-1-fg.docx
April 01, 2025 - SAY:
The four key strategies to prevent MRSA and SSIs include the following: nasal decolonization, preoperative … in the presentation Antimicrobial Prophylaxis Part 2. … Antimicrobial Prophylaxis Part 2. … The CUSP team discovered that the patient completed preoperative decolonization with both chlorhexidine … the most appropriate antimicrobial prophylaxis.
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www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/004-ss-antimicrobial-prophylaxis-part-2.pptx
April 01, 2025 - Antimicrobial Prophylaxis Part 2
4
Access the Part 1 presentation on the Antimicrobial Prophylaxis … Timing of Preoperative Antibiotic Prophylaxis and Surgical Site Infections: TAPAS, an observational cohort … Preoperative penicillin allergy testing in patients undergoing cardiac surgery. … Timing of Preoperative Antibiotic Prophylaxis and Surgical Site Infections: TAPAS, an observational cohort … Preoperative penicillin allergy testing in patients undergoing cardiac surgery.
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www.ahrq.gov/es/hai/patient-safety-resources/advances-in-hai/hai-article3.html
June 01, 2014 - Antimicrobial Prophylaxis and Decrease Gram-Positive Surgical Site Infections for Cardiac and Orthopedic … Antimicrobial Prophylaxis and Decrease Gram-Positive Surgical Site Infections for Cardiac and Orthopedic … ASHP Therapeutic Guidelines on Antimicrobial Prophylaxis in Surgery. … Quality standard for antimicrobial prophylaxis in surgical procedures. … Antimicrobial prophylaxis for surgery. The Medical Letter 2009;7(82):47-99.
29.
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www.ahrq.gov/hai/patient-safety-resources/advances-in-hai/hai-article3.html
June 01, 2014 - Antimicrobial Prophylaxis and Decrease Gram-Positive Surgical Site Infections for Cardiac and Orthopedic … Antimicrobial Prophylaxis and Decrease Gram-Positive Surgical Site Infections for Cardiac and Orthopedic … ASHP Therapeutic Guidelines on Antimicrobial Prophylaxis in Surgery. … Quality standard for antimicrobial prophylaxis in surgical procedures. … Antimicrobial prophylaxis for surgery. The Medical Letter 2009;7(82):47-99.
29.
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www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/017-ss-importance-ssi-mrsa-prevention-fg.docx
April 01, 2025 - chlorhexidine gluconate (CHG) skin antisepsis, antimicrobial prophylaxis, and evidence-based infection … (if appropriate)
· Surgery: Hand hygiene, antimicrobial prophylaxis, skin preparation prior to incision … The four strategies are: nasal decolonization, preoperative CHG skin antisepsis, antimicrobial prophylaxis … Slide 22
Antimicrobial Prophylaxis
SAY:
Antimicrobial prophylaxis is important for the prevention … antisepsis, antimicrobial prophylaxis, and evidence-based infection prevention.
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www.ahrq.gov/hai/tools/mrsa-prevention/surgery/mrsa-surveillance.html
April 01, 2025 - MRSA and SSI Prevention Phases
The Evidence for MRSA Decolonization
Nasal Decolonization
Use of Preoperative … Chlorhexidine Antisepsis
Decolonization Resources
Antimicrobial Prophylaxis
Hand Hygiene in the … Contact Precautions
Optimizing Environmental Cleaning
Perioperative Infection Prevention Strategies
Preoperative … You are also able to tell which patients have a higher risk of a MRSA SSI and to use antimicrobial prophylaxis … prophylaxis selection Documents: MRSA Surveillance – Slides (PPTX, 2 MB) MRSA Surveillance – Facilitator
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psnet.ahrq.gov/node/49533/psn-pdf
March 01, 2007 - Timing and Clinical Decision-Making
Importantly, the patient in this case did not receive preoperative … Systematic efforts to improve the selection of empiric antibiotics, through antimicrobial stewardship … ASHP Therapeutic Guidelines on Antimicrobial Prophylaxis in Surgery. … Computerized antimicrobial decision
support: an offline evaluation of a database-driven empiric antimicrobial … cmd=retrieve&db=pubmed&dopt=abstract&list_uids=17082202
antimicrobial stewardship.
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www.ahrq.gov/hai/tools/mrsa-prevention/surgery/index-clinical-topics.html
April 01, 2025 - Chlorhexidine Antisepsis
Decolonization Resources
Antimicrobial Prophylaxis
Hand Hygiene in the … Use of Preoperative Chlorhexidine Antisepsis In surgery, skin antisepsis is an important practice to … Antimicrobial Prophylaxis All patients who undergo cardiac, hip and knee joint replacement, and spinal … fusion surgical procedures must take some form of antimicrobial prophylaxis. … Preoperative Hair Removal This section discusses recommendations for hair removal prior to surgery.
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psnet.ahrq.gov/web-mm/staggered-sensitivity-results
May 01, 2013 - is a "low priority," is inconvenient, and does not fit into the usual preoperative workflow. … teams and clear roles and responsibility for timing of the preoperative dose. … Systematic efforts to improve the selection of empiric antibiotics, through antimicrobial stewardship … ASHP Therapeutic Guidelines on Antimicrobial Prophylaxis in Surgery. … Computerized antimicrobial decision support: an offline evaluation of a database-driven empiric antimicrobial
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www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/065-ssi-prevention-periop-roadmap-checklist.docx
April 01, 2025 - Yes No N/A
Antimicrobial Prophylaxis Choices (recommended per local standard)
Is patient known to … the pre-op area)
Questions
Answers
Hand Hygiene maintained throughout pre-op setting
Yes No
Antimicrobial … Prophylaxis
(started in pre-op if has a long infusion time, i.e., Vancomycin)
Yes No N/A
If yes, … room)
Questions
Answers
Hand hygiene prior to and throughout procedure
Yes No
Appropriate antimicrobial … prophylaxis for procedure per local agreement
Yes No
Antibiotic administered prior to incision
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www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/093-universal-targeted-decolonization-one-pager.docx
April 01, 2025 - · Proven effective in several large studies and across several surgery types.2,3,5
· Can inform antimicrobial … prophylaxis selection and need for contact precautions. … who might be colonized with methicillin-resistant Staphylococcus aureus (MRSA).
· Unable to inform antimicrobial … prophylaxis selection or need for contact precautions … Effectiveness of a bundled intervention of decolonization and prophylaxis to decrease Gram positive surgical
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www.ahrq.gov/hai/tools/mrsa-prevention/surgery/preoperative-hair-removal.html
April 01, 2025 - MRSA Prevention Toolkit: Targeting SSI
Preoperative Hair Removal
Previous Page Next Page … MRSA and SSI Prevention Phases
The Evidence for MRSA Decolonization
Nasal Decolonization
Use of Preoperative … Chlorhexidine Antisepsis
Decolonization Resources
Antimicrobial Prophylaxis
Hand Hygiene in the … Contact Precautions
Optimizing Environmental Cleaning
Perioperative Infection Prevention Strategies
Preoperative … Perioperative Infection Prevention Strategies – Facilitator Guide (DOCX, 7 MB) One-Pagers One-Pager: Preoperative
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www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/022-ss-mrsa-surveillance.pptx
April 01, 2025 - prophylaxis selection
| 2
AHRQ Safety Program for MRSA Prevention | Surgical Services
MRSA Surveillance … prophylaxis to prevent SSIs, access the Antimicrobial Prophylaxis section of the toolkit website … prophylaxis
Tissue oxygenation
Normothermia
| 24
Access the Perioperative Roadmap Tool. … Preoperative MRSA surveillance approaches contain pros and cons. … prophylaxis selection, and guide and evaluate intervention and prevention strategies
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www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/011-ss-decolonization-strategies-fg.docx
April 01, 2025 - These include nasal decolonization, preoperative skin antisepsis with chlorhexidine (CHG), antimicrobial … Antimicrobial prophylaxis was also informed by carrier status. … Antimicrobial prophylaxis is covered in more detail in the presentations “Antimicrobial Prophylaxis” … and “Antimicrobial Prophylaxis: Beyond the Basics.” … colonized with MRSA, and this can be used to inform antimicrobial prophylaxis selection and contact isolation