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Showing results for "populations".

1721. AHRQ Slide Template 2009 (ppt file)
      effectivehealthcare.ahrq.gov/sites/default/files/presentation.ppt
      August 01, 2009 - PICOTS Population: primary populations of interest are followed by subpopulations Intervention: hierarchy … metabolism of warfarin) that have been studied for associations with a variety of outcomes in different populations … The “minor allele” is the less frequent of the two alleles in the population. … considering as a “variant allele” the allele with the lowest frequency (i.e., the minor allele) in populations … The least-biased studies may not be applicable to the population of interest.

1722. Despite steadily increasing health care expenditures in the United States, improved health outcomes and quality remain elusive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-interventions-comparing_methods.pdf
      November 01, 2008 - , health care expenditures in the United States are increasing much faster than the health of the population … clear understanding of the clinical context to ensure that the review focuses on the appropriate population … review compares the tradeoffs of multiple alternatives, each of which may vary with the underlying population … abilities of different oral diabetes drugs to control blood glucose may depend in important ways on the populations … check on whether results observed in trials appear to hold up under more representative settings and populations

1723. Despite steadily increasing health care expenditures in the United States, improved health outcomes and quality remain elusive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_slutsky_comparing_medical_interventions.pdf
      November 01, 2008 - , health care expenditures in the United States are increasing much faster than the health of the population … clear understanding of the clinical context to ensure that the review focuses on the appropriate population … review compares the tradeoffs of multiple alternatives, each of which may vary with the underlying population … abilities of different oral diabetes drugs to control blood glucose may depend in important ways on the populations … check on whether results observed in trials appear to hold up under more representative settings and populations

1724. Topic 0586 LUTS Secondary to BPH NSD FINAL (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0713-140625.pdf
      January 07, 2014 - The scope of this topic, including populations, interventions, comparators, and outcomes, will be further … Staff-Generated PICO (1 of 2) Population(s): Adult males, aged 45 or older, showing lower urinary tract … optimal pharmacotherapy treatment options for patients with LUTS/BPH Staff-Generated PICO (2 of 2) Population

1725. Calcineurin_Inhibitors_Protocol_FINAL_10-07-2014 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
      October 08, 2014 - PICOTS The population for all key questions includes adult kidney transplant recipients treated with … With regard to alternative regimens (KQ3), population will include patients switched from standard dosing … Analytic Framework for Calcineurin Inhibitors for Kidney Transplant Intermediate-Term Population Interventions … Data for these patient populations will be analyzed separately through subgroup analyses. … Potential covariates include population descriptors, including baseline immunological risk factors for

1726. Evidence Report on the (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-nitrous-oxide_research-protocol.pdf
      August 24, 2011 - PICOTS Population(s) Pregnant women in first and second stages of labor (up to birth), other attendees … will also focus the review on studies published in English; included studies may include non–U.S. populations … Table 1: Inclusion/Exclusion Criteria Category Criteria Study population Pregnant women in first … methods and results to enable use and adjustment of the data and results Studies with mixed patient populations … August 24, 2011 13 for any factors limiting the ability to apply the intervention to other populations

1727. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay_research-protocol.pdf
      May 02, 2011 - Plasma cell dyscrasias (PCDs) are a spectrum of disorders characterized by the expansion of a population … Eligibility Criteria  Population(s) Adults (≥18 years of age) o KQ 1: Patients who have … Figure 1 depicts the key questions described in the previous section within the context of the PICOTS (Populations … Criteria for Inclusion/Exclusion of Studies in the Review We will use the eligibility criteria for populations … summarized in narrative form and in summary tables that tabulate the important features of the study populations

1728. Evidence Report on the (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-centered-medical-home_research-protocol.pdf
      February 23, 2012 - The PCMH is a cross-cutting topic, relevant to broad areas of health care and patient populations. … Population(s): 1. … In this particular instance, we are focused on application to primary care populations. … respect to applicability is whether the outcomes are different across studies that recruit different populations … multi-disciplinary group of clinical, content, and methodologic experts who provide input in defining populations

1729. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/atrial-fibrillation_research-protocol.pdf
      May 22, 2012 - PICOTS (Populations, Interventions, Comparators, Outcomes, Timing, Settings) • Populations: o Adults … Inclusion and exclusion criteria PICOTS Element Inclusion Criteria Exclusion Criteria Populations … to the commonly held concepts of high quality, including the following: a clear description of the population … practice, paying special attention to study eligibility criteria, demographic features of the enrolled population … in comparison to the target population, characteristics of the intervention used in comparison with

1730. Liver-Cancer-Therapy Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer-therapy_research-protocol.pdf
      November 28, 2012 - It is not known which patient populations with HCC will benefit the most from these therapies. … (RCTs) and nonrandomized comparative studies (observational, case-control, and cohort studies) of populations … noncomparative observational studies (case series) to assess comparative effectiveness and harms in populations … Such evidence will require extrapolation to the population of interest. … prognosis when compared with adults, these findings may not be applicable to the pediatric patient populations

1731. 8 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
      November 01, 2008 - CER authors should routinely search for and include well-designed and reported case-control and population-based … follow patients for an extended period of time, but they usually enroll a more highly selected population … reliable, all studies should be comparable in terms of quality, factors related to applicability (population … , women, or minority populations) Table 3. … quality, consistency of evidence, directness of evidence, other modifying factors Applicability Population

1732. 8 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
      November 01, 2008 - CER authors should routinely search for and include well-designed and reported case-control and population-based … follow patients for an extended period of time, but they usually enroll a more highly selected population … reliable, all studies should be comparable in terms of quality, factors related to applicability (population … , women, or minority populations) Table 3. … quality, consistency of evidence, directness of evidence, other modifying factors Applicability Population

1733. PowerPoint Presentation (ppt file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-applicability.ppt
      June 01, 2012 - Some studies will not reflect the specific populations, settings, or management strategies identified … These issues include patient populations, management strategies, time effects, and secular trends. … Populations and study designs of included studies heterogeneous with varied findings Data not stratified … Challenges include heterogeneous populations and study designs plus data that is not adjusted for key … If populations studied had different levels of disease severity, will it affect the performance of the

1734. PowerPoint Presentation (ppt file)
      effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-applicability.ppt
      June 01, 2012 - Some studies will not reflect the specific populations, settings, or management strategies identified … These issues include patient populations, management strategies, time effects, and secular trends. … Populations and study designs of included studies heterogeneous with varied findings Data not stratified … Challenges include heterogeneous populations and study designs plus data that is not adjusted for key … If populations studied had different levels of disease severity, will it affect the performance of the

1735. Hepatitis-C Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
      November 01, 2012 - The population was patients with chronic HCV infection who were receiving antiviral therapy. … Good-quality studies clearly describe the population, setting, interventions, and comparison groups; … understanding the applicability of studies, such as whether the publication adequately described the study population … versus no SVR after antiviral therapy and reduced mortality comes from a study performed in a VA population … Hepatitis C virus genotypes and viral concentration in participants of a general population survey

1736. Mrsa-Screening-2010 Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/mrsa-screening-2010_executive.pdf
      January 01, 2010 - patients in the absence of signs or symptoms of infection in an effort to identify the underlying population … By detecting the larger population of colonized individuals, conventional precautions, at the very … The patient population included all ambulatory patients (outpatients) and hospitalized patients (inpatients … PICOTS (Population Intervention, Comparator, Outcome, Timing, and Setting) for the Key Questions … Population All ambulatory patients (outpatients) and all hospitalized patients (inpatients).

1737. Effective Health Care (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0316_03-12-2009.pdf
      January 01, 2009 - The scope of this topic, including populations, interventions, comparators, and outcomes, will be further … Population(s): Patients diagnosed with hypertension (defined BP 140/90) Intervention(s): Self-measured

1738. Stroke Prevention in Atr ial Fibr illation Patients: A Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-afib-update_research-protocol-amended.pdf
      October 27, 2017 - The estimated prevalence of AF is 0.4 percent to 1 percent in the general population,3, 4 occurring … percent in patients with a CHADS2-VASc score of 9.15 A number of studies have examined the appropriate populations … help inform decision-making related to whether these medications are safe and effective in patient populations … in comparison to the target population, characteristics of the intervention used in comparison with … question LAA left atrial appendage MRI magnetic resonance imaging PE pulmonary embolism PICOTS Populations

1739. depression-pregnancy-postpartum-protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-pregnancy-postpartum_research-protocol.pdf
      March 29, 2013 - Evidence-based Practice Center (PNW EPC) revised the KQs and developed eligibility criteria to identify the populations … • Interventions: As a result of the change in population (above) the scope of interventions was … Studies in the Review The PNW EPC developed preliminary inclusion/exclusion criteria, identifying populations … inclusion/exclusion criteria reflect revisions made following the kickoff call: Inclusion Criteria Populations … multidisciplinary group of clinical, content, and methodological experts who provide input in defining populations

1740. Effective Health Care (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0332_07-29-2010.pdf
      January 01, 2010 - The scope of this topic, including populations, interventions, comparators, and outcomes, will be further … Nomination Summary: The nominator questions whether screening among the general adult male population … Staff-Generated PICO Population(s): Males over the age of 50 (or at age 40 if baseline is sought), males