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Total Results: 334 records

Showing results for "phase".

  1. www.uspreventiveservicestaskforce.org/uspstf/methods-and-processes/uspstf-analytic-framework-child-and-adolescent-health-topics
    October 01, 2017 - In Phase I, USPSTF members consider whether the risk factor assessment is accurate and screening is effective … In Phase II, USPSTF members consider whether the intervention works to maintain or improve health.
  2. www.uspreventiveservicestaskforce.org/home/getfilebytoken/VKGPkVjto7K4yfUHBKEHBA
    January 01, 2025 - During the intervention phase of the WHI trial (median dura- tion, 5.6 years), women assigned to combined … risk of invasive breast cancer vs women assigned to placebo during the median 7.2-year intervention phase … tically significantly higher risk of stroke vs those who received pla- cebo during the intervention phase … In the WHI intervention phase, women who received combined estrogen and progestin vs placebo were less … and a posttrial observational phase, for an average of 12.6 years).
  3. www.uspreventiveservicestaskforce.org/uspstf/recommendation/menopausal-hormone-therapy-preventive-medication-december-2017
    December 12, 2017 - During the intervention phase of the WHI trial (median duration, 5.6 years), women assigned to combined … risk of invasive breast cancer vs women assigned to placebo during the median 7.2-year intervention phase … estrogen alone had an increased risk of deep vein thrombosis during the mean 7.1-year intervention phase … In the WHI intervention phase, women who received combined estrogen and progestin vs placebo were less … and a posttrial observational phase, for an average of 12.6 years).
  4. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary16/blood-pressure-in-children-and-adolescents-hypertension-screening-october-2013
    February 15, 2013 - A: 10-day run-in Phase B: 4-wk dose-ranging Phase C: 2-wk withdrawal versus placebo Phase D: 1-y open-label … safety phase 12.1 (2.6) 376 screened 255 eligible 253 randomized Fosinopril Overall study … placebo (33.9%) and combined fosinopril treatment groups (34.3%) Phase D: Specific AEs: Headache: 51 … 1 randomized to 3 different doses, phase 2 randomized washout; 43 clinical centers in North and South … and 2-wk placebo controlled washout phase Median 12 y 110 enrolled Enalapril Drug-related AEs
  5. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Aqm6uW6_HrTRVJ-EVCVaRV
    March 01, 2013 - 2 (included placebo SBP Group D: 22.1 (95% CI, 25.7 to 1.5) Phase 2 results (fair) comparison) … B (included placebo NR Group C: 20.4 6 11.0 (P = NS) Phase B results ,12 y) comparison) 43 sites … A: 10-day run-in 255 eligible Phase C: Incidence of AEs similar presenceofassociatedclinical between … B: 4-wk dose-ranging 253 randomized Phase D: Specific AEs: Phase C: 2-wk withdrawal versus Headache … : 51/253 (20%) placebo Phase D: 1-y open-label safety Nasopharyngitis: 24/253 (10%) phase Cough:
  6. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary28/menopausal-hormone-therapy-preventive-medication
    November 01, 2022 - 94 The risk reduction was statistically significant during cumulative (trial and postintervention phase … During the WHI intervention phase, persons using combination therapy had statistically significantly … statistically significantly fewer persons who had been randomized to hormone therapy during the trial phase … , precise for cumulative phase Fair quality; few events and short-term follow-up for mortality outcome … (intervention phase only) Low for benefit Diabetes 1 RCT; 16 , 53 during intervention period
  7. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary12/cervical-cancer-screening-2012
    October 18, 2011 - For primary HPV screening compared with cytology, we found 1 RCT (NTCC phase 2; 49,196 participants) … Phase 2 of NTCC referred many women for colposcopy who would instead have been retested in the United … The  Appendix Table  details other interpretation and quality issues with NTCC phase 2. … Four large, fair-quality RCTs 46 , 49 —NTCC phase 1, POBASCAM, Swedescreen, and ARTISTIC (comprising … * NTCC Phase I and NTCC Phase II, maximum follow-up after invitation to Round 2 reported.
  8. www.uspreventiveservicestaskforce.org/home/getfilebytoken/-BtXpm9NU6xbgHFntRvA76
    November 01, 2020 - during the first four years of the trial, with nearly 50,500 total palpations performed.1 A two phase
  9. www.uspreventiveservicestaskforce.org/uspstf/document/letter-to-the-editor-and-response-from-the-evidence-based-practice-center--human-papillomavirus-testing-to-screen-for-cervical-cancer/cervical-cancer-screening-2012
    February 15, 2012 - In addition, a pooled analysis of phase 1 (cotesting) and phase 2 (HPV alone) of the NTCC 6 trial also … complete data from two screening rounds was available from only two of four cotesting trials (NTCC Phase … I, ARTISTIC) and one primary HPV screening trial (NTCC Phase II).
  10. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/hepatitis-c-screening
    March 02, 2020 - Randomized phase 3 trial of ombitasvir/paritaprevir/ritonavir for hepatitis C virus genotype 1b-infected … Phase 2b trial of interferon-free therapy for hepatitis C virus genotype 1. … (12 and 8 weeks) in hepatitis C virus genotype 1-infected patients without cirrhosis: OPTIMIST-1, a phase … treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase … Efficacy and safety of elbasvir/grazoprevir and sofosbuvir/pegylated interferon/ribavirin: a phase III
  11. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Rn7dRezgMx5syB-erQKoKt
    November 01, 2022 - The risk reduc- tion was statistically significant during cumulative (trial and post- intervention phase … Dur- ing the WHI intervention phase, persons using combination therapy had statistically significantly … During the intervention phase of the WHI, participants assigned to estrogen plus progestin had a statis … , precise for cumulative phase Fair quality; few events and short-term follow-up for mortality outcome … (intervention phase only) Low for benefit Diabetes 1 RCT16,53; during intervention period, 976 events
  12. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/cervical-cancer-screening
    August 21, 2018 - Among women 35 years and older, only NTCC Phase I had a significantly higher RR for cotesting compared … In the NTCC Phase II protocol, all hrHPV-positive results were referred directly to colposcopy. 14 , … hrHPV Cotesting Colposcopy rates were reported in only 2 trials of cotesting (ARTISTIC and NTCC Phase … Only the NTCC Phase I trial reported age-stratified colposcopy and false-positive rates. … a One publication (Ronco 2010 14 ) includes 2 trials (NTCC Phase I and NTCC Phase II), so it is counted
  13. www.uspreventiveservicestaskforce.org/home/getfilebytoken/NZ_RQWxMMR8Vym-yJuqru-
    May 23, 2019 - Type 2 diabetes mellitus includes an asymptomatic preclinical phase; the length of this phase is un- … Screening tests can detect diabetes in its preclinical phase. … The magnitude of additional benefit of initiating tight glycemic control during the preclinical phase … Does Diabetes Have an Asymptomatic Preclinical Phase, and How Long Is It? … The natural history of diabetes includes an asymptom- atic preclinical phase.
  14. www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/cervical-cancer-screening
    August 21, 2018 - The NTCC Phase II trial found that hrHPV testing alone had a cumulative CIN 3+ detection rate twice that … Colposcopy rates were higher for hrHPV testing alone than for cytology alone in 1 of 3 trials (NTCC Phase … The NTCC Phase I, ARTISTIC, and POBASCAM trials reported 2 rounds of screening at 3- to 5-year intervals … I, Swedescreen, ARTISTIC, and POBASCAM), as well as a single trial of primary hrHPV testing (NTCC Phase … The long preclinical phase from infection to development of precancerous lesions and cervical cancer
  15. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/diabetes-mellitus-type-2-in-adults-screening-2003
    February 03, 2003 - Type 2 diabetes mellitus includes an asymptomatic preclinical phase; the length of this phase is unknown … Screening tests can detect diabetes in its preclinical phase. … The magnitude of additional benefit of initiating tight glycemic control during the preclinical phase … Does Diabetes Have an Asymptomatic Preclinical Phase, and How Long Is It? … The natural history of diabetes includes an asymptomatic preclinical phase.
  16. JAMA JATS (pdf file)

    www.uspreventiveservicestaskforce.org/home/getfilebytoken/dvDjnZzW9PDxzKBauB4QxA
    August 21, 2018 - I and NTCC Phase II), so it is counted as 2 publications instead of 1. … In the NTCC Phase II protocol, all hrHPV-positive results were referred directly to colposcopy.14,20 … The NTCC Phase II trials re- ported no CIN 3 or invasive cervical cancer cases among screen- negative … hrHPV Cotesting Colposcopy rates were reported in only 2 trials of cotesting (ARTISTIC and NTCC Phase … Only the NTCC Phase I trial reported age-stratified colpos- copy and false-positive rates.
  17. www.uspreventiveservicestaskforce.org/uspstf/recommendation/cervical-cancer-screening
    August 21, 2018 - The NTCC Phase II trial found that hrHPV testing alone had a cumulative CIN 3+ detection rate twice that … Colposcopy rates were higher for hrHPV testing alone than for cytology alone in 1 of 3 trials (NTCC Phase … The NTCC Phase I, ARTISTIC, and POBASCAM trials reported 2 rounds of screening at 3- to 5-year intervals … I, Swedescreen, ARTISTIC, and POBASCAM), as well as a single trial of primary hrHPV testing (NTCC Phase … The long preclinical phase from infection to development of precancerous lesions and cervical cancer
  18. www.uspreventiveservicestaskforce.org/home/getfilebytoken/k2QHcwuK4NkvxFXhvGrbwY
    May 01, 2004 - 2002 10 limit 9 to (human and English language) 11 limit 10 to (clinical trial or clinical trial, phase … i or clinical trial, phase ii or clinical trial, phase iii or clinical trial, phase iv or controlled
  19. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary36/menopausal-hormone-therapy-preventive-medication-2012
    May 29, 2012 - disease and osteoporotic fractures, we selected results reported at the end of the trial intervention phase … For conditions that were initiated during exposure but continued after the intervention phase, such as … cancer, we used results reported at the end of the trial's postintervention phase, if available. … The study closed during the recruitment phase, follow-up was short, the power of the study was greatly … diabetes; gallbladder disease; cognitive function; and urinary incontinence Postintervention phase
  20. www.uspreventiveservicestaskforce.org/home/getfilebytoken/WEqCV3NvnZAeLdC_pp6nVK
    October 01, 2018 - Randomized phase 3 trial of ombitasvir/ paritaprevir/ritonavir for hepatitis C virus genotype 1b-infected … Phase 2b trial of interferon-free therapy for hepatitis C virus genotype 1. … (12 and 8 weeks) in hepatitis C virus genotype 1-infected patients without cirrhosis: OPTIMIST-1, a phase … treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase … Efficacy and safety of elbasvir/grazoprevir and sofosbuvir/pegylated interferon/ribavirin: a phase III

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