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Total Results: 839 records

Showing results for "phase".

81. Acute Treatments for Episodic Migraine: Surveillance Report 3 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-3.pdf
    August 01, 2022 - Lasmiditan is an effective acute treatment for migraine: a phase 3 randomized study. … Ubrogepant for the acute treatment of migraine: pooled efficacy from ACHIEVE I and ACHIEVE II phase … Rimegepant for the acute treatment of migraine: subgroup analyses from 3 phase 3 clinical trials by … STOP 301: A Phase 3, open-label study of safety, tolerability, and exploratory efficacy of INP104, … Evaluation of injection-site-related adverse events with galcanezumab: a post hoc analysis of phase

82. Systematic Review on Nonopioid Pharmacologic Treatments for Chronic Pain: Surveillance Report 2 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-2-nonopioid-pharm-chronic-pain.pdf
    April 01, 2022 - Efficacy and safety of fasinumab in patients with chronic low back pain: a phase II/III randomised … in patients with knee pain due to osteoarthritis: an exploratory post hoc analysis of a Japanese phase … or chronic low back pain with early pain reduction: an exploratory post- hoc analysis of Japanese phase … Open- label phase 3 study of diclofenac conjugated to hyaluronate (diclofenac etalhyaluronate: ONO- … ][TM]s effect in Chinese patients with chronic pain due to osteoarthritis: post hoc analyses of a phase

83. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0274_03-10-2008.pdf
    January 01, 2008 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

84. Draft - Primary Hypofractionated Radiation Therapy for Localized Prostate Cancer: Appendix D2 Tables (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-draft-appendix-d2.xlsx
    January 01, 2024 - , the pelvic node CTV and primary CTV were treated to 46 Gy in 23 fractions, and in the second phase, … The initial phase targeted the entire pelvis, including the prostate and 1 cm of the seminal vesicles … The second phase consisted of a 30 Gy boost in 15 Fx to the prostate and the proximal 1 cm of the SVs … In phase I, the low-dose PTV received 46 Gy in 23 fractions. … In phase II the high-dose PTV received an additional 32 Gy in 16 fractions, bringing the total dose to

85. Untitled (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/suicide-prevention_research-protocol.pdf
    December 23, 2015 - The results of this phase will inform KQs 1, 2 and 3. … This phase will further inform KQ 1. … The primary data abstraction processes are described in detail for each phase of the review. … The final coding schema will be similar to the schema used for the systematic review phase. … in the data synthesis phase of KQ 1.

86. The Refinement of Topics for Systematic Reviews: Lessons and Recommendations From the Effective Health Care Program (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-refinement_methods.pdf
    January 01, 2013 - We use the term “provisional” to refer to the elements of the initial topic refinement phase. … previous phase (e.g., Key Questions developed in the initial topic refinement). … to the systematic review phase. … Initial Topic Refinement Phase During the initial topic refinement phase, the topic refinement team … • Input about issues not adequately addressed in the initial topic refinement phase.

87. Research Protocol: Improving Cultural Competence To Reduce Health Disparities for Priority Populations (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/cultural-competence_research-protocol.pdf
    July 09, 2014 - The literature set identified at this phase will be examined from a content analysis perspective for …  ii.pt.   41   clinical  trial,  phase  iii.pt.   42   clinical  trial,  phase …  i.pt.   40   clinical  trial,  phase  ii.pt.   41   clinical  trial,  phase   … iii.pt.   42   clinical  trial,  phase  iv.pt.   43   controlled  clinical  trial.pt …  i.pt.   40   clinical  trial,  phase  ii.pt.   41   clinical  trial,  phase  

88. Functional-Limitations-Horizon-Scan-High-Impact-1306 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/functional-limitations-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - Results The table below lists the 17 topics for which (1) preliminary phase III data were available … In phase III trials, icatibant provided significant symptom relief within about 2 hours and initial … Placebo- controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis. … Placebo- controlled phase 3 study of oral BG-12 or glatiramer in multiple sclerosis. … ThromboGenics' microplasmin phase III program progressing according to schedule. [internet].

89. #05 DEPRESSION (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1312.pdf
    October 01, 2014 - Results The table below lists the five topics for which (1) preliminary phase III data for drugs were … Completed phase III trials did not demonstrate statistical superiority of mifepristone over placebo … Paul, MN) are in phase III development for DBS for treating BPD and MDD. … Reclaim/Activa trials for MDD have an anticipated completion date of October 2014; phase III trials … III clinical trial.9 Three completed phase III trials did not demonstrate superiority of mifepristone

90. #05 DEPRESSION (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - inclusion are those interventions expected to be within 0–4 years of potential diffusion (e.g., in phase … Results The table below lists the seven topics for which (1) preliminary phase III data on drugs or … Mifepristone for treating PMD is being investigated in one phase III clinical trial. … Three phase III trials did not individually demonstrate statistical superiority of mifepristone over … Paul, MN) are both in phase III development for DBS for MDD.

91. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0007_03-17-2008.pdf
    January 01, 2008 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

92. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0260_07-16-2010.pdf
    January 01, 2010 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

93. #05 DEPRESSION (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_june_2012.pdf
    January 01, 2012 - Results The table below lists the 12 topics for which (1) preliminary phase III data on drugs or phase … Mifepristone for treating PMD is being investigated in one phase III clinical trial. … Reclaim is in phase III trials for MDD with an anticipated completion date of October 2014; Libra is … also in phase III trials. … Jude Medical is evaluating its Libra ® DBS system for treatment-resistant depression in the phase

94. Evidence-based Practice Center Systematic Review Protocol: Therapies for Clinically Localized Prostate Cancer (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-protocol_amended110619.pdf
    November 02, 2019 - versus active surveillance in men with low-risk prostate cancer (CLIN1001 PCM301): an open-label, phase … Patients With Low- Risk Prostate Cancer Treated With Hypofractionated vs Conventional Radiotherapy: A Phase … 26 (763246) 29 27 and 28 (43063) 30 limit 29 to (clinical trial, all or clinical trial, phase … i or clinical trial, phase ii or clinical trial, phase iii or clinical trial, phase iv or clinical

95. PULMONARY with "Discussions" in Exec Summary (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - inclusion are those interventions expected to be within 0–4 years of potential diffusion (e.g., in phase … Results The table below lists three topics in the system for which (1) preliminary phase III or later … Several phase III trials have been cosponsored by the Cystic Fibrosis Foundation, of Bethesda, MD. … In a randomized, double-blind, placebo-controlled, phase III trial, cosponsored by the Cystic Fibrosis … Vertex Pharmaceuticals initiates phase 3 registration program for VX-770, an oral CFTR potentiator

96. PULMONARY with "Discussions" in Exec Summary (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pulmonary_hi_impact.pdf
    April 01, 2012 - III trials for pharmaceuticals or biotechnologies or in phase II or a trial with some preliminary … The table below lists the three topics for which (1) preliminary phase III were available for drugs … , or phase II, III or later data were available for devices; (2) information was compiled by November … The drug is in several phase III clinical trials cosponsored by the Cystic Fibrosis Foundation. … Vertex Pharmaceuticals initiates phase 3 registration program for VX-770, an oral CFTR potentiator

97. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/tethered-spinal-cord-protocol.pdf
    July 19, 2023 - Lipomyelomeningocele" OR "tight filum syndrome" Recruitment: Completed studies Study Results: All studies Phase … : Phase 2, Phase 3, Phase 4 ICTRP No limits “tethered cord syndrome” OR “tethered spinal cord … lying spinal cord” OR “filum terminale syndrome OR Lipomyelomeningocele” OR “tight filum syndrome” Phase … : Phase 2, Phase 3, Phase 4 Cochrane Database of Systematic Reviews tethered cord syndrome OR tethered

98. Treatment Resistant Depression Surveillance FINAL (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_surveillance.pdf
    April 01, 2016 - therapy [CBT or interpersonal therapy [IPT]]) differ in efficacy or effectiveness in treating acute phase … treatments compare with pharmacological treatments in efficacy or effectiveness in treating acute-phase … Current Literature Analysis: • We identified a small phase II RCT examining individuals with MDD who … Tier 3: A small phase II RCT (n=60) examined individuals with MDD who had responded to ECT and … RESULTS: Of 90 MDD patients starting the acute phase, 70% responded and 47% remitted to acute ECT.

99. Disposition of Comments: Comparative Effectiveness Review 235_Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: An Update of the PTSD-Repository Evidence Base (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-comments.pdf
    November 04, 2020 - Since the Phase 1 work and report, we have worked closely with the National Center for PTSD to obtain … Since the Phase 1 work and report, we have worked closely with the National Center for PTSD to obtain … For this phase of development, as recommended by the TEP and NCPTSD, treatments were categorized according … of the PTSD-Repository and updated in this next phase of work. … in a subsequent article highlighting the updates to the PTSD- Repository completed in this second phase

100. Protocol Amendment - Safety of Vaccines 030413 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccines-safety-protocol-130325.pdf
     September 18, 2012 - The clinical evaluation of a vaccine typically consists of three phases.8 Phase I studies—which typically … Phase II studies evaluate the immunogenicity of the vaccine and provide preliminary estimates on the … Phase III trials provide the information on a vaccine’s safety and effectiveness that is required to