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Showing results for "phase".

  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0024_06-09-2008.pdf
    January 01, 2008 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase
  2. effectivehealthcare.ahrq.gov/products/copd/research
    October 11, 2019 - ), early pulmonary rehabilitation commenced before hospital discharge during the initial most acute phase … ), early pulmonary rehabilitation commenced before hospital discharge during the initial most acute phase
  3. effectivehealthcare.ahrq.gov/sites/default/files/ebc-challenge-case-130621.pdf
    June 01, 2013 - Summary of Challenge Activities and Key Considerations Phase of Challenge Activity Examples of Relevant … Although it is not necessary to finalize the judging panel in the pre-challenge phase, hosts should … The first is the during launch phase, which is an occasion to introduce external stakeholders to the … The second opportunity is during the operations phase, or while the challenge is under way. … To maintain interest and generate buzz during the operations phase, AcademyHealth produced hard-copy
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/primary-research-design_research.pdf
    January 01, 2012 - Phase 1 involved a focused literature search to identify existing frameworks and processes that have … In phase 2, we convened a multidisciplinary group with varied expertise to develop a stepwise framework … In phase 3, we identified two systematic reviews and applied this framework to their results. … Phase 4 invited external opinions from additional experts to further refine the framework. … Phase 4 In a final phase, we invited external opinions from four additional experts with experience
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-future_research.pdf
    April 01, 2013 - Table 4 and Appendix D: Three pending phase 2 trials have been removed from the report. … The scope is limited to phase 3 and 4 trials. … NCT01497366: A phase 3, multicenter, randomized, active-controlled study to investigate the safety … NCT01497834: A phase 3 Japanese study of BMS-790052 plus BMS-650032 combination therapy in chronic … II/III Simeprevir Study, or Who Received DAA Treatment in a Tibotec- Sponsored Phase I Study.
  6. effectivehealthcare.ahrq.gov/sites/default/files/dementia_horizon-scan-high_impact-1306-revised.pdf
    July 09, 2013 - Results The table below lists the three topics for which (1) preliminary phase III data for drugs were … The Horizon Scanning System is tracking several drugs in late-phase development. … Flutemetamol has completed a U.S.- based phase III trial, while another phase III trial is ongoing. … -based phase III trial is ongoing for flutemetamol while another phase III trial has been completed … Phase 1 study of the Pittsburgh compound B derivative 18F-flutemetamol in healthy volunteers and
  7. effectivehealthcare.ahrq.gov/sites/default/files/06_devdelays_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - inclusion are those interventions expected to be within 0–4 years of potential diffusion (e.g., in phase … priority area (among the 13 topics being tracked as of October 26, 2012), for which (1) preliminary phase … III data for drugs, phase II or III data for devices and procedures, or some human data for off-label … Several drugs in phase I and II development are aimed at targeting social symptoms of ASD and are being … ineligible for consideration in the High Impact report at this time because they have not yet produced phase
  8. effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in phase … Biogen (Cambridge, MA) has advanced this candidate drug to phase III testing, despite initial analysis … of intermediate doses used in phase I testing showing no clinical efficacy. … early probable AD and may also delay disease progression; the developers have initiated a pivotal phase … The developer is conducting phase III trials with AVP-786 and AVP-923 for this indication, and we continue
  9. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1412.pdf
    October 01, 2015 - Results The table below lists the four topics for which (1) preliminary phase III data on drugs, phase … Three phase III trials on lumacaftor have been completed, and one phase III extension trial is ongoing … In the phase III ASCEND trial, patients (n=555) with IPF treated with pirfenidone had a significant … In two replicate phase III trials (INPULSIS-1 and INPULSIS-2), patients (n=1,066) with IPF who were … A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis.
  10. effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1506.pdf
    December 01, 2015 - Results The table below lists the five topics for which (1) preliminary phase III data for drugs were … Clinicians based their off-label decisions on results from a phase II trial demonstrating high SVR12 … A number of other manufacturers also have all-oral HCV DAA regimens in phase II or phase III development … In the phase III, randomized controlled VALENCE trial, patients (n=419) with chronic HCV genotype 2 … In the phase III, open-label, randomized controlled ION-3 trial, patients (n=647) with chronic HCV
  11. effectivehealthcare.ahrq.gov/sites/default/files/dementia_hi_impact.pdf
    January 01, 2012 - III trials for pharmaceuticals or biotechnologies or in phase II or a trial with some preliminary … -based phase III trial is ongoing for flutemetamol. … Two agents in late-phase development for this purpose are discussed here. … -based phase III trial is ongoing for flutemetamol. … Results from a phase II trial were released in 2009 and were updated in 2010.
  12. effectivehealthcare.ahrq.gov/products/bipolar-disorder-treatment/research-protocol
    June 23, 2014 - responses to treatment by bipolar type (type I or type II), polar episode (depression or mania), and phase … for people with bipolar disorder, including disease-specific characteristics such as bipolar type, phase … Results will be organized by bipolar type, phase, and patient characteristics. … Some columns or cells may be exploded into their own matrix, for example phase severity, again depending … clinical trial, phase ii.pt. clinical trial, phase iii.pt. clinical trial, phase iv.pt.
  13. effectivehealthcare.ahrq.gov/sites/default/files/04_dementia_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - inclusion are those interventions expected to be within 0–4 years of potential diffusion (e.g., in phase … Results The table below lists the three topics for which (1) preliminary phase III data for drugs were … -based phase III trials are ongoing for flutemetamol, and the manufacturer anticipates a premarket … binding to beta-amyloid aggregates and did not bind to tau, synuclein, or other targets. 12,13 PhasePhase 1 study of the Pittsburgh compound B derivative 18F-flutemetamol in healthy volunteers and
  14. effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1506.pdf
    December 01, 2015 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in phase … In late 2014, investigators reported top-line results from a phase III study examining metadoxine for … second tracked topic covers dasotraline, an investigational triple-reuptake inhibitor currently in a phase … II/III trial for treating pediatric ADHD and a phase III trial for treating adult ADHD; each of these
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/phenylketonuria_surveillance.pdf
    January 15, 2013 - A small Phase 2 trial of PEGylated phenylalanine ammonium lyase (PAL), an enzyme that breaks down Phe … , was completed in September 2012; the Phase 3 trial is expected to begin in the 2nd quarter of 2013 … BioMarin Announces Decision to Start Phase 3 Program for PEG-PAL in 2Q 2013. … Preliminary Phase 2 Results Indicate Convenient and Accelerated Dosing Regimen Identified. … 1: baseline Phase 2: (2 weeks) doubling of natural protein intake Phase 3: (4 weeks) daily BH4
  16. effectivehealthcare.ahrq.gov/sites/default/files/ahrq-healthcare-horizon-scan-protocol-operations-manual_130826.pdf
    August 01, 2013 - Is this being called an innovation AND is it in late phase development? … Is this being called an innovation AND is it in late phase clinical development? If so, select. 8. … Is the intervention in late-phase development for the U.S. health care system? … The “track-only” designation means that the intervention is in late-phase trials, but late-phase data … 1 and phase 2 clinical cancer trials X X X X X X A-9 Table 1.
  17. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - phase II data for devices and procedures, or some human data for off-label uses or programs were … Investigators in two phase III trials (RISE and RIDE trials) tested ranibizumab in patients with DME … This drug will compete with other drugs in phase III trials, such as Iluvien and aflibercept (Eylea … (Durham, NC) in September 2011 to begin a phase III program of six trials. 62,63 In the completed … Intarcia presents positive ITCA 650 phase 2 study results for type 2 diabetes at EASD.
  18. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - phase II data for devices and procedures, or some human data for off-label uses or programs were … Investigators in two phase III trials (RISE and RIDE trials) tested ranibizumab in patients with DME … This drug will compete with other drugs in phase III trials, such as Iluvien and aflibercept (Eylea … (Durham, NC) in September 2011 to begin a phase III program of six trials. 62,63 In the completed … Intarcia presents positive ITCA 650 phase 2 study results for type 2 diabetes at EASD.
  19. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/14_substance_abuse_potential_high_impact_2012-12-11.pdf
    January 01, 2012 - inclusion are those interventions expected to be within 0–4 years of potential diffusion (e.g., in phase … Results The table below lists two topics for which (1) preliminary phase III data were available for … The buprenorphine implant is in two phase III trials, one of which is funded by the National Institute … Titan Pharmaceuticals presents phase 3 probuphine data at Society for Neuroscience annual meeting … Titan Pharmaceuticals announces positive top line results in confirmatory phase 3 trial of probuphine
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
    June 23, 2014 - responses to treatment by bipolar type (type I or type II), polar episode (depression or mania), and phase … for people with bipolar disorder, including disease-specific characteristics such as bipolar type, phase … rates will be excluded at the abstraction phase … Results will be organized by bipolar type, phase, and patient characteristics. … i.pt. 40 clinical trial, phase ii.pt. 41 clinical trial,  phase iii.pt. 42 clinical trial, phase

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