Results

Total Results: 1,112 records

Showing results for "phase".

421. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
     February 01, 2012 - also excluded patients who did not meet minimum response criteria or were nonadherent during a run-in phase … before the double-blind treatment phase.

422. Innovations in Stakeholder Engagement Conference Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/innovations_in_stakeholder_engagement_conference_summary2.pdf
     October 01, 2011 - Innovations in Stakeholder Engagement Conference Summary Innovations in Stakeholder Engagement Conference Summary 2 AHRQ Community Forum Overview of Types of Online Collaborative Platforms Chris Haller, Founder and CEO, Urban Interactive Studios Online collaborative platforms provide an avenue for individua…

423. S44 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s44.pdf
     October 01, 2007 - ORIGINAL ARTICLE Designed Delays Versus Rigorous Pragmatic Trials Lower Carat Gold Standards Can Produce Relevant Drug Evaluations Malcolm Maclure, ScD,* Bruce Carleton, PharmD,† and Sebastian Schneeweiss, MD, ScD‡§¶ Background: Centralized administrative databases enable low-cost pragmatic randomized trials (PRTs) …

424. Medical Therapies for Children With Autism Spectrum Disorder—An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-medical-executive-170505.pdf
     May 01, 2017 - KQ4: What is the evidence that effects measured at the end of the treatment phase predict long-term … investigative team also scanned the reference lists of studies included after the full-text review phase … atomoxetine No serious adverse events reported; most harms attenuated over open label extension phase

425. First and Second Generation Antipsychotics for Children and Young Adults-Comparative Effectiveness Review Update | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/antipsychotics-children-update/research-protocol
     December 07, 2015 - The subgroups have been modified slightly to include phase and features of disorder (e.g., acute mania … schizophrenia, schizoaffective disorder, substance/medication-induced psychotic disorder, or prodromal phase … vary with respect to patient characteristics, such as age, sex, race/ethnicity, medical comorbidities, phase … When the study design changes during the process of a research program, for example from an RCT phase … to a controlled, observational phase, we will consider these two different studies.

426. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in phase … Results The table below lists the four topics for which (1) preliminary phase III data for drugs or … Liraglutide is under investigation for obesity treatment in a four-part, phase III clinical trial ( … People with type 2 diabetes achieve 6% weight loss with liraglutide 3 mg in phase 3a obesity trial … Novo Nordisk reports 8% weight loss in phase 3a obesity trial with liraglutide 3 mg.

427. Multidisciplinary Postacute Rehabilitation for Moderate to Severe Traumatic Brain Injury in AdultsBrain Injury in Adults Surveillance Report 08082016 CCKK CC final clean (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation-surveillance-160902.pdf
     September 02, 2016 - $$$randomized$controlled$trial/$(416302)$ 11$$$$$clinical$trial/$(500056)$ 12$$$$$clinical$trial,$phase … $i.pt.$(16112)$ 13$$$$$clinical$trial,$phase$ii.pt.$(26010)$ 14$$$$$clinical$trial,$phase$iii.pt.$( … 11141)$ 15$$$$$clinical$trial,$phase$iv.pt.$(1169)$ 16$$$$$controlled$clinical$trial.pt.$(90707)$ … $Electromyogram"lengthening$velocity$relation$in$ plantar$flexors$during$stance$phase$of$gait$in$patients … $The$Relationship$of$Health$Locus$ of$Control$and$Health"Related$Quality$of$Life$in$the$Chronic$Phase

428. Ced-Appendix-3 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
     June 24, 2022 - NICE_cancer Data Use data from a registry, from ongoing studies (for example, further follow-up of Phase … II and III trials, or Phase IV or pharmacovigilance studies), or set up new data collection. … NICE_cancer Data_source Use data from a registry, from ongoing studies (for example, further follow-up of Phase … II and III trials, or Phase IV or pharmacovigilance studies), or set up new data collection.

429. Crosscutting-Horizon-Scan-High-Impact-1412 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in phase … Results The table below lists three topics for which (1) preliminary or published phase III data were … medication regimens tested in clinical trials has been implicated as a significant reason that many phase … Failure to determine these thresholds during Phase 2 is believed to be one of the main reasons for … Phase 3 failures.”30 One phase IV clinical trial is ongoing to evaluate the cost and perception of

430. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_disposition-comments.pdf
     June 01, 2010 - While one Phase 2 trial and one Phase 3 trial were both able to show a reduction in bleeding with the … A case in point is the recently published Novo Nordisk sponsored Phase 2 cardiac trial (F7CARD-1610) … The pooling of dose-escalation studies with Phase 2 or Phase 3 studies in the efficacy analyses is a … non-parallel safety studies (Mayer 2005b31 and Mayer 200632) are inappropriately combined with the Phase … Recombinant activated factor VII for acute intracerebral hemorrhage: US phase IIA trial. .Neurocrit

431. Antipsychotics-Children-Surveillance-150120 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-surveillance-150120.pdf
     October 01, 2014 - A phase 2a randomized, parallel group, dose-ranging study of molindone in children with attention-deficit … A phase 2a randomized, parallel group, dose-ranging study of molindone in children with attention-deficit … We found one-long term (72 weeks) RCT reporting on the maintenance phase (Findling, 2012). … One completed suicide occurred during the OLE phase. … A phase 2a randomized, parallel group, dose-ranging study of molindone in children with attention-deficit

432. #05 DEPRESSION (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in phase … Results The table below lists the three topics for which (1) preliminary mid- or late-phase data for … topics in this priority area were eligible for consideration for high-impact potential because no phase … indication, and Janssen plans to also apply for breakthrough therapy status.38,39 Janssen has two new phase … that all available scopolamine formulations had some degree of antidepressant efficacy.75 In the phase

433. Payer Perspectives on Improving Usability of Effective Health Care Products: Bridging the Gap Between Information Needs and Evidence Translation | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/payer-usability/white-paper
     February 03, 2014 - One possible approach is to present a summary of review findings to payers during the peer review phase

434. Rt-Bone-Metatases-Qa-Tables-Appendix-F (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/rt-bone-metatases-qa-tables-appendix-F.xlsx
     January 01, 2019 - Unclear No Yes (CROs) No (PROs) Yes No No Unclear Unclear Unclear Yes Poor Sprave, 2018 Randomized phase

435. Cer-265-Radiation-Bone-Disease-App-F (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-app-f.xlsx
     January 01, 2019 - Unclear No Yes (CROs) No (PROs) Yes No No Unclear Unclear Unclear Yes Poor Sprave, 2018 Randomized phase

436. Treatments for Seasonal Allergic Rhinitis | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/allergy-seasonal/research-protocol
     March 08, 2012 - An early phase allergic response follows: Mast cell degranulation releases preformed inflammatory mediators … Four to 12 hours after allergen exposure, a late-phase allergic response may occur. … The late-phase response consists primarily of nasal congestion and is mediated by the influx and activation … inflammatory T-cells and eosinophils. 2 , 21 , 22 Ongoing, prolonged allergen exposure and repeated late-phase … and abstraction A complete set of data to be extracted will be developed during the abstraction phase

437. PowerPoint Presentation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/krishnan_ahrq-mcda-presentation.pdf
     August 27, 2012 - PowerPoint Presentation Use of Analytic Hierarchy Process to elicit stakeholder preferences for prioritizing research August 27, 2012 Jerry A. Krishnan, MD, PhD (jakris@uic.edu) Professor of Medicine and Public Health Associate Vice President for Population Health Sciences on behalf of the CONCERT …

438. Maternal and Fetal Effects of Mental Health Treatments in Pregnant and Breastfeeding Women: A Systematic Review of Pharmacological Interventions | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/mental-health-pregnancy/protocol
     January 11, 2019 - interventions in women with any mental health condition during the preconception, pregnancy, or postpartum phase … We will retrieve and review the full text of all titles included during the title/abstract review phase

439. Retention Strategies for Medications for Addiction Treatment in Adults With Opioid Use Disorder: A Rapid Evidence Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/mat-retention-strategies-rapid-review-1.pdf
     August 01, 2020 - week stabilization, 2 week taper) Retention: # of SMM (standard medical management) visits Phase … 1: 4.4 (1.5) ODC vs 4.5 (1.5) SMM alone (z=1.24, p=0.39) Phase 2: 14.1 (4.4) ODC vs 13.9 … 1 (n=2) or Phase 2 (n=3) taper. … KQ3: A history of ever using heroin was associated with lower Phase 2 success rates while taking … buprenorphine- naloxone Chronic pain at baseline was not related to outcomes either in Phase 1 or

440. Long-Term Drug Therapy and Drug Holidays for Osteoporotic Fracture Prevention | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/osteoporosis-fracture-prevention/research-protocol
     April 12, 2018 - blind method/ (159463) single blind method/ (27137) clinical trial/ (553719) clinical trial, phase … i.pt. (20676) clinical trial, phase ii.pt. (33325) clinical trial, phase iii.pt. (15646) clinical … trial, phase iv.pt. (1673) controlled clinical trial.pt. (100423) randomized controlled trial.pt