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  1. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_executive.pdf
    April 01, 2011 - KQ3: Are there any identifiable changes early in the treatment phase that predict treatment outcomes? … KQ4: What is the evidence that effects measured at the end of the treatment phase predict long-term functional … Early Results in the Treatment Phase That Predict Outcomes The literature offers almost no information … The effects of PECS teaching to Phase III on the communicative interactions between children with autism
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children-future_research.pdf
    February 01, 2012 - In the final phase, a combined Key Informant group was formed, comprised of seven members from the original … shared with the combined Key Informant panel for consideration during the Key Question generation phase … Randomized phase III trial 281 patients (.4 – 49 years) 1999 – 2005 FU: median 3.8 years … Phase II treatment study 60 (ages 6 to 59 years) 9/1994 - End date not provided United States … Phase II/III Treatment Study 530 6/2006 – 4/2024 United States FU: 10 years HDCT with ASCR
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout-management-disposition-160721.pdf
    March 15, 2016 - The term “Dietary” is used in the key questions as they were finalized during the topic refinement phase … Then, we can talk about phases as this is (usually) a second phase after intercritical gout. … with oral ULT, indeed as cited by the AHRQ draft review, are not long enough in the non-extension phase … Moreover, remodeling of tissue urate crystal deposits, particularly in the early phase of ULT, is clearly … FACT trial with both allopurinol and febuxostat, and also in the pegloticase program trials early phase
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-value-of-information_research.pdf
    June 01, 2011 - Recently, a Phase III trial documented a statistically significant improvement in survival with a combination … Outcomes, Approach to VOI Calculations, and Data We used the published overall survival curves from the Phase … We estimated a distribution of mean costs arising out of a sample size similar to that of the Phase … Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase … Comparative effectiveness study [41) - Drug price: Drug Topics Red Book (42) - Survival curves: Phase
  5. effectivehealthcare.ahrq.gov/sites/default/files/adhd_disposition-comments.pdf
    October 01, 2011 - later version ES-4 Peer Reviewer #7 Executive Summary Of the 54% of children entering the rx phase … Sentences added to document that 60% entered open label titration and 46 % entered open label extension phase … statement on the preceding page that 165 “entered …the preliminary open label medication safety lead-in phase … possible explanation for the difference between clinician and parent ratings in the parallel study phase … Same page, 3rd paragraph, 4th line: need to change “theparallel phase” to “the parallel phase.”
  6. CARDIOVASCULAR (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/cardiovascular-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in phase … Results The table below lists the five topics for which (1) preliminary phase III data for drugs, phase … lower-than-anticipated U.S. growth rates.66 The company had previously announced that it had initiated a phase … inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase … Aegerion Pharmaceuticals presents data from phase 3 extension study of Juxtapid (lomitapide) capsules
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_disposition-comments.pdf
    November 27, 2012 - However, the AHRQ report gives equal importance to data from telaprevir’s Phase II (PROVE1 and PROVE2 … ) trials and the Phase III (ADVANCE and ILLUMINATE) trials. … Additionally, the telaprevir Phase III trials also used an FDA labeled regimen outlined in the product … AHRQ found the Phase III trial that compared the telaprevir dosing that was ultimately approved by
  8. effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-32-pharm-non-pharm-ptsd.pdf
    May 14, 2019 - This is an item of note and will be considered for possible expansion for the next phase of database … sponsors in case this table is translated into a functioning database during the future development phase … other recommendations for future expansion to our funding partners as they look forward to the next phase
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19-appendix-table-B-1.xlsx
    January 24, 2022 - Prospective cohort 6 Hematology-oncology Patients with hematologic malignancy (HM) during the acute phase … multiple myeloma (MM), myelodysplastic/ myeloproliferative syndromes (MDS/MPN) who survived the acute phase … Controls: 54 (33-66) NR Total: 33 (52.4) HM patients: 26 (58) Controls: 7 (39) NR N and S proteins, fluid-phase
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-treatment_research-protocol.pdf
    February 10, 2010 - our understanding of the literature and discussions with key informants during the topic-refinement phase … www.effectivehealthcare.ahrq.gov Published Online: April 25, 2011 Page 11 of 18 results at each phase
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/musculoskeletal-complaints-tests-children_disposition-comments.pdf
    March 07, 2012 - Inter-rater agreement is calculated during the pilot phase of the selection process as part of our procedure … The need for third party adjudication was rare once the pilot phase of level 2 screening was completed … Many of the national laboratories screen for ANAs using solid phase assays.
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_clinician.pdf
    June 01, 2016 - Management of Infantile Hemangioma Management of Infantile Hemangioma Background Infantile hemangioma (IH) is the most common tumor of childhood and is estimated to affect about 4 to 5 percent of children, with higher prevalence in premature infants and in whites. IH tends to go through growth and involution ph…
  13. PATIENTSLIKEME (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/clifford.pdf
    May 29, 2025 - amount of mouse work in retesting every available therapeutic that was -- that has gone through a phase
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections-surveillance-140925.pdf
    January 01, 2014 - Cycle 1 (October 2012) One meta-analysis of two recently completed phase three trials55 showed that … Babady et 2010 Evaluation of Phase 1: 44 positive glutamate N/A sensitivity and GDH-CYT and Xpert PCR … infection and typing of the NAP1 strain at a cancer hospital stool samples from 39 patients Phase … 2012 Safety analysis A total of 728 adults 116 healthy N/A; tolerability, In this safety analysis of phase … Crook8 2012 Meta-analysis of 2 phase three RCCT n = 1164 -Fiadxomicin 200 mg twice daily for 10
  15. effectivehealthcare.ahrq.gov/sites/default/files/osteoarthritis-knee-update-executive-170505.pdf
    May 01, 2017 - growth factor and designed to be injected intraarticularly), which to date, have been tested only in Phase … These include the need to determine in Phase 1 trials whether high-intensity strength training, aimed … Tissuegene-C (InvossaTM) in patients with osteoarthritis: A phase II trials. … Tissuegene-C (Invossa™) in patients with osteoarthritis: A phase II trials. … TG-C), TGF-β1 transduced chondrocyte, improved clinical scores in patients with osteoarthritis: A phase
  16. effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1406.pdf
    June 01, 2014 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in phase … Results The table below lists five topics for which (1) preliminary or published phase III data were … medication regimens tested in clinical trials has been implicated as a significant reason that many phase … Failure to determine these thresholds during Phase 2 is believed to be one of the main reasons for … Phase 3 failures.”30 Manufacturer and regulatory status: Proteus Digital Health, Inc., (Redwood City
  17. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in phase … Results The table below lists the three topics for which (1) preliminary phase III data for drugs and … phase II (or equivalent) data for devices and procedures were available; (2) information was compiled … more than 80 countries worldwide.17 Another competitor, the Obalon intragastric balloon, is in late-phase … July 2015, Pi-Sunyer and colleagues reported on comparative weight loss in 3,731 patients in the phase
  18. S50 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s50.pdf
    October 01, 2007 - ORIGINAL ARTICLE Practice-Based Evidence Study Design for Comparative Effectiveness Research Susan D. Horn, PhD, and Julie Gassaway, RN, MS Objectives: To describe a new, rigorous, comprehensive practice- based evidence for clinical practice improvement (PBE-CPI) study methodology, and compare its features, advantag…
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_disposition-comments.pdf
    April 03, 2013 - During the Assessment phase, the patient is initially asked to identify image, negative cognition, emotion … restrictions, the following is an accurate description of the treatment: EMDR therapy is an eight phase … The first phase (initial report) has been completed and is described in the report. … In phase 1, the Committee task was to collect data from the DoD and the VA on programs and methods … The second phase (not yet completed) will focus on Source: http://effectivehealthcare.ahrq.gov/search-for-guides-reviews-and-reports
  20. effectivehealthcare.ahrq.gov/sites/default/files/deliberative-methods-facilitation-transcript.pdf
    May 29, 2025 - When we get to the consultation phase of the model typically what’s happening is we’re asking participants … So what are we actually trying to do at the consultation phase? … on your participants’ energy level, or comfort, or understanding of where you’re going in the next phase

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