December 01, 2014 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in
phase … Results
The table below lists the four topics for which (1) preliminary phase III data for drugs or … Liraglutide is
under investigation for obesity treatment in a four-part, phase III clinical trial ( … People with type 2 diabetes achieve 6% weight
loss with liraglutide 3 mg in phase 3a obesity
trial … Novo Nordisk reports 8% weight loss in phase 3a
obesity trial with liraglutide 3 mg.
November 01, 2020 - The next phase of this project will focus collection of the baseline and follow-up PHQ-9s, as
well as … useful to guide future
implementations of the harmonized measures.
12
Next Steps
The next phase
December 01, 2014 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in
phase … Results
The table below lists three topics for which (1) preliminary or published phase III data were … medication regimens tested in clinical
trials has been implicated as a significant reason that many phase … Failure to determine these thresholds
during Phase 2 is believed to be one of the main reasons for … Phase 3 failures.”30
One phase IV clinical trial is ongoing to evaluate the cost and perception of
December 01, 2014 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in
phase … Results
The table below lists the three topics for which (1) preliminary mid- or late-phase data for … topics in this priority area were eligible
for consideration for high-impact potential because no phase … indication, and Janssen plans to also apply for breakthrough
therapy status.38,39 Janssen has two new phase … that
all available scopolamine formulations had some degree of antidepressant efficacy.75
In the phase
August 01, 2020 - week stabilization, 2
week taper)
Retention: # of SMM
(standard medical
management) visits
Phase … 1: 4.4
(1.5) ODC vs
4.5 (1.5) SMM alone
(z=1.24, p=0.39)
Phase 2:
14.1 (4.4) ODC vs
13.9 … 1 (n=2)
or Phase 2 (n=3)
taper. … KQ3: A history of
ever using heroin was
associated with lower
Phase 2 success
rates while taking … buprenorphine-
naloxone
Chronic pain at
baseline was not
related to outcomes
either in Phase 1 or
June 01, 2015 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in
phase … Results
The table below lists the three topics for which (1) preliminary phase III data for drugs were … microbiota therapy for irritable bowel disease that are in clinical trials but have not yet reported
phase
August 01, 2018 - Conclusion
We found no high or moderate-strength evidence for any
intervention to effectively treat any phase … The efficacy and tolerability of
cariprazine in acute mania associated with bipolar I disorder: A
phase … Cariprazine in the
treatment of acute mania in bipolar I disorder: a double-blind,
placebo-controlled, phase
November 03, 2014 - The acute phase is self-limited and characterized by recurrent
attacks of synovitis (articular inflammation … 1ß-inhibitory anti-
inflammatory agents currently approved for treatment of rheumatoid arthritis and in
Phase
February 01, 2012 - also excluded
patients who did not meet minimum response criteria or
were nonadherent during a run-in phase … before the
double-blind treatment phase.
October 01, 2007 - ORIGINAL ARTICLE
Designed Delays Versus Rigorous Pragmatic Trials
Lower Carat Gold Standards Can Produce Relevant Drug Evaluations
Malcolm Maclure, ScD,* Bruce Carleton, PharmD,† and Sebastian Schneeweiss, MD, ScD‡§¶
Background: Centralized administrative databases enable low-cost
pragmatic randomized trials (PRTs) …
October 01, 2011 - Innovations in Stakeholder Engagement Conference Summary
Innovations in Stakeholder Engagement Conference Summary 2
AHRQ Community Forum
Overview of Types of Online Collaborative Platforms
Chris Haller, Founder and CEO, Urban Interactive Studios
Online collaborative platforms provide an avenue for individua…
May 01, 2017 - KQ4: What is the evidence that effects measured at the
end of the treatment phase predict long-term … investigative team also scanned the reference
lists of studies included after the full-text review phase … atomoxetine
No serious adverse events reported; most harms
attenuated over open label extension phase
June 24, 2022 - NICE_cancer Data Use data from a registry, from ongoing studies (for example, further follow-up of Phase … II and III trials, or Phase IV or pharmacovigilance studies), or set up new data collection. … NICE_cancer Data_source Use data from a registry, from ongoing studies (for example, further follow-up of Phase … II and III trials, or Phase IV or pharmacovigilance studies), or set up new data collection.
June 01, 2010 - While one Phase 2 trial and one Phase 3 trial were both able
to show a reduction in bleeding with the … A case in point is the recently published Novo Nordisk
sponsored Phase 2 cardiac trial (F7CARD-1610) … The pooling of dose-escalation studies with Phase 2 or
Phase 3 studies in the efficacy analyses is a … non-parallel
safety studies (Mayer 2005b31 and Mayer 200632) are inappropriately
combined with the Phase … Recombinant activated
factor VII for acute intracerebral hemorrhage: US phase IIA trial.
.Neurocrit
October 01, 2014 - A phase 2a randomized, parallel group, dose-ranging study of
molindone in children with attention-deficit … A phase 2a randomized, parallel group, dose-ranging
study of molindone in children with attention-deficit … We found one-long term (72 weeks) RCT
reporting on the maintenance phase (Findling,
2012). … One completed
suicide occurred during the OLE phase. … A phase 2a randomized, parallel group, dose-ranging study of molindone in children with attention-deficit