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effectivehealthcare.ahrq.gov/sites/default/files/manges.pdf
May 29, 2025 - ENVIRONMENTAL PROTECTION AGENCY
INNOVATIONS CONFERENCE -- ENVIRONMENTAL PROTECTION AGENCY
SPEAKER: ELLEN MANGES,
SENIOR ADVISOR, OFFICE OF SOLID WASTE AND EMERGENCY RESPONSE (OSWER)
ENVIRONMENTAL PROTECTION AGENCY (EPA)
MANGES: My name is Ellen Manges. I'm a senior advisor. I…
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effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1412.pdf
December 01, 2014 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in
phase … Results
The table below lists the three topics for which (1) preliminary phase III or bioequivalence … Two late-phase multicenter trials are ongoing, and we continue to track this
topic.
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effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1312.pdf
December 01, 2013 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in
phase … Results
The table below lists the three topics for which (1) preliminary phase III data for drugs were … The Horizon Scanning System is tracking several
drugs in late-phase development.
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effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1312.pdf
December 01, 2013 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in
phase … Results
The table below lists two topics for which preliminary phase III data were available for a drug … The 6-month buprenorphine implant completed phase III trials, one of
which was funded by the National
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effectivehealthcare.ahrq.gov/sites/default/files/12_pregnancy_potential_high_impact_2012-12-11.pdf
January 01, 2012 - inclusion are those interventions expected to be within 0–4 years of potential diffusion (e.g., in
phase … Results
The table below lists the three topics for which (1) preliminary phase III data were available … for
drugs, phase II or III data were available for devices and procedures, or some human data were
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/prevent-hai-protocol.pdf
April 16, 2024 - ,ab)
#15 RCTs ('random sample'/de OR 'randomization'/de OR 'randomized
controlled trial'/exp OR 'phase … 3':ti,ab OR 'phase iii':ti,ab
OR random*:ti,ab OR RCT:ti,ab)
#16 Observational/
Cohort Studies/
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ocr-protocol-final_1.pdf
December 18, 2019 - dilation for fetal
distress
• Cervical assessment at
time of admission (e.g.,
latent vs. active phase … dilation for fetal
distress
• Cervical assessment
at time of admission
(e.g., latent vs. active
phase … dilation for fetal
distress
• Cervical assessment
at time of admission
(e.g., latent vs. active
phase … dilation for fetal
distress
• Cervical assessment at
time of admission (e.g.,
latent vs. active phase
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research.pdf
March 01, 2013 - Trospium chloride improves overactive
bladder symptoms: a multicenter phase III
trial. … Efficacy and
safety of solifenacin succinate 10 mg once
Daily: A multicenter, phase III, randomized … Multicenter phase III trial studying trospium
chloride in patients with overactive bladder. … A
pooled analysis of three phase III studies to
investigate the efficacy, tolerability and
safety … Trospium chloride improves overactive
bladder symptoms: a multicenter phase III
trial.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation-surveillance-160902.pdf
May 29, 2025 - $$$randomized$controlled$trial/$(416302)$
11$$$$$clinical$trial/$(500056)$
12$$$$$clinical$trial,$phase … $i.pt.$(16112)$
13$$$$$clinical$trial,$phase$ii.pt.$(26010)$
14$$$$$clinical$trial,$phase$iii.pt.$( … 11141)$
15$$$$$clinical$trial,$phase$iv.pt.$(1169)$
16$$$$$controlled$clinical$trial.pt.$(90707)$ … $Electromyogram"lengthening$velocity$relation$in$
plantar$flexors$during$stance$phase$of$gait$in$patients … $The$Relationship$of$Health$Locus$
of$Control$and$Health"Related$Quality$of$Life$in$the$Chronic$Phase
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_surveillance.pdf
April 01, 2012 - AHRQ Comparative Effectiveness Review
Surveillance Program
CER #32:
Diagnosis and Treatment of Obstructive Sleep Apnea
in Adults
Original release date:
August 8, 2011
Surveillance Report:
July, 2012
Key Findings:
- The conclusions for KQ2 (phased testing), KQ3
(preoperative screening), KQ6 (compliance…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_executive.pdf
December 01, 2011 - (i.e., dye is strongly
persistent after three cardiac cycles of the washout
phase and either does not … that clears normally and is either gone or only
mildly/moderately persistent at the end of the
washout phase … (i.e., dye is gone or is
mildly/moderately persistent after three cardiac
cycles of the washout phase … and noticeably
diminishes in intensity during the washout phase),
similar to that in an uninvolved artery … Blush that
is of only mild intensity throughout the washout
phase but fades minimally is also classified
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effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1312.pdf
December 01, 2013 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in
phase … Results
The table below lists the four topics for which (1) preliminary phase III data for drugs and … biologics or phase II data for devices and procedures were available; (2) information was compiled … Phase III
trials reported that patients with SBS treated with teduglutide can significantly reduce … day), once daily.65
Clinical trials: In results of a randomized, double-blind, placebo-controlled, phase
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effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1312.pdf
December 01, 2013 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in
phase … Results
The table below lists a single topic for which (1) preliminary phase III data were available … study of oxytocin for treating ASDs
using the company’s OptiNose nasal drug delivery technology; a phase
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effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1406.pdf
February 01, 2015 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in
phase … Results
The table below lists the one topic for which (1) preliminary late-phase clinical trial data … The latter group is lead sponsor on the largest ongoing trial, a phase II/III trial investigating
intranasal
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-221-copd-comments_0.pdf
October 11, 2019 - interventions, such as community care after hospital
discharge, and we focused on the most acute phase … systematic review did not include health services
interventions, and we focused on the initial most acute
phase … rehabilitation commenced before hospital
discharge and that during ECOPD refers to the initial
most acute phase … body vibration
commenced before hospital discharge and that during
ECOPD refers to the most acute phase
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effectivehealthcare.ahrq.gov/sites/default/files/study-eligibility-criteria.ppt
January 01, 2000 - beginning abstract review
Selecting Criteria
Broader criteria are often set at the abstract review phase … and refined to be more specific for the full-text review phase, so this process is likely to occur twice
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effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1506.pdf
June 01, 2015 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in
phase … Results
The table below lists the three topics for which (1) preliminary phase III data for drugs (or … preliminary late-phase clinical trial data for off-label drug indications) was available; (2)
information … A phase II/III trial enrolling
patients with MDD (n=40) found that intravenous scopolamine, administered
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/telehealth-during-COVID-19-amendments.pdf
April 28, 2022 - Each of these considerations had been discussed with the stakeholders during the topic
refinement phase … : the era of COVID-19 (March 2020-present)
KQ1d: During the first 4 months or beyond the initial
phase … the era of COVID-19
(March 2020-present)
KQ1d: During the first 4 months
or beyond the initial phase … 20
Appendix A: Cost Outcomes
Infrastructure
Cost of implementation and sustaining phase
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/anal-cancer-protocol.pdf
September 26, 2023 - The Key Questions (KQs)
The KQs were posted online for public comments during the pre-award phase and … chemotherapy is superior to radiotherapy alone in the treatment of locally
advanced anal cancer: results of a phase … maintenance chemotherapy for treatment of
squamous-cell carcinoma of the anus (ACT II): a randomised, phase
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer_research-protocol.pdf
July 24, 2013 - The diagnosis phase involves the
use of additional tests (radiological and/or histopathological) to … technology is currently in use or not, and the technical aspects of
each technology (such as row number, phase