Results

Total Results: 839 records

Showing results for "phase".

261. First- and Second-Generation Antipsychotics in Children and Young Adults: Systematic Review Update--Executive Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update_executive.pdf
     January 01, 2018 - with respect to patient characteristics, such as age, sex, race/ethnicity, medical comorbidities, phase … to any meaningful extent; results were similar when applying sensitivity analysis for the prodrome phase … One trial had a controlled extension phase of 30 weeks, one trial had a placebo-controlled maintenance … b Dowgraded for imprecision. c Downgraded for ROB. d When two studies examining the depressive phase … Most RCTs were examining acute phase treatment in patients either naïve to or not taking antipsychotics

262. Disposition of Comments: Comparative Effectiveness Review No. 239: Acute Treatments for Episodic Migraine (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-239-episodic-migraine-comments.pdf
     December 29, 2020 - Celecoxib Oral Solution, 25 Mg/ml) in the Acute Treatment of Episodic Migraine: Efficacy Results from Two Phase

263. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/11_pepticulcer_potential_high_impact_june_2012.pdf
     January 01, 2012 - inclusion are those interventions expected to be within 0–4 years of potential diffusion (e.g., in phase … Results The table below lists the four topics for which (1) preliminary phase III data for drugs and … biologics and phase II data for devices and procedures were available; (2) information was compiled … Phase III trials reported that patients with SBS treated with teduglutide can significantly reduce … Phase 3 Gattex (teduglutide) data highlight potential new treatment for adults with short bowel syndrome

264. Pharmacologic Management of Acute Pain by EMS in the Prehospital Setting Protocol Amendment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
     January 28, 2019 - . double blind method/ 66. single blind method/ 67. clinical trial/ 68. clinical trial, phase … i.pt. 69. clinical trial, phase ii.pt. 70. clinical trial, phase iii.pt. 71. clinical trial … , phase iv.pt. 72. controlled clinical trial.pt. 73. randomized controlled trial.pt. 74.

265. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_disposition-comments.pdf
     September 01, 2011 - also focused on the primary George, et al, 2010 – this studywas included during the update search phase … Arch Gen Psychiatry 2006, 63:1337-1344 Janicak, (2010) Included during the update search phase post … NIMH Another recent paper worth citing is the continuation phase of the large industry-sponsored rTMS … Janicak (2010) – We agree and the study was included during the update search phase post submission … in addition includes the adverse event experience observed during the 6 month long-term follow-up phase

266. Research White Paper Managing Missing Data in Patient Registries Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
     February 01, 2018 - equally important to implement strategies to minimize missing data during the registry’s operational phase … set at the study outset, with comparisons made to actual rates of missing data during the analysis phase … considered as part of the registry protocol and analysis plan development, and during the analytic phase

267. Back (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/back.pdf
     January 01, 2011 - • Audio recording interview studies of consent conversations for phase 1 o Important  information

268. Topic 0613 Tympanostomy Tubes NSD FINAL (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0765-150129.pdf
     November 03, 2014 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

269. Topic 0494 Tacrolimus Monitoring and Treatment Renal Transplantation NSD FINAL (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0583-131115.pdf
     March 13, 2013 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

270. Crosscutting-Horizon-Scan-High-Impact-1512 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1512.pdf
     December 01, 2015 - Results The table below lists four topics for which (1) preliminary phase III data for drugs were … available; (2) phase II data for devices were available; (3) any type of outcomes data were available … A phase IV trial is ongoing for patients with tuberculosis. … Failure to determine these thresholds during Phase 2 is believed to be one of the main reasons for … Phase 3 failures.”9 One phase IV clinical trial (NCT01960257) is ongoing to evaluate the cost and perception

271. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/phenylketonuria_research-protocol.pdf
     March 29, 2011 - /exclusion criteria we selected based on our understanding of the literature, the topic refinement phase … predetermined inclusion/exclusion criteria or for which we have insufficient information at the abstract phase … During the review phase of the study, the Project Coordinator will report to the Methods and Content … predetermined inclusion/exclusion criteria or for which we have insufficient information at the abstract phase … During the review phase of the study, the Project Coordinator will report to the Methods and Content

272. CERs Report cover (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/future05-breastcancer-10-5-2010final.pdf
     September 01, 2010 - Study design Phase I: Identification & Recruitment of Stakeholders Phase … to Reduce the Risk of Primary Breast Cancer in Women” Question and answer discussion Phase IV … : Questionnaire Administration Phase IV: Questionnaire Administration Web-based Writable PDF … Genetic polymorphisms in phase I and phase II enzymes and breast cancer risk associated with menopausal … Phase II Trial—Breast Cancer Chemoprevention by Lovastatin. 52. NCT00080756.

273. Restless-Legs Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs_research-protocol.pdf
     December 16, 2011 - 6 double blind method/ (112853) 7 single blind method/ (15532) 8 clinical trial, phase … i.pt. (11643) 9 clinical trial, phase ii.pt. (18390) 10 clinical trial, phase iii.pt. (6549 … ) 11 clinical trial, phase iv.pt. (642) 12 controlled clinical trial.pt. (83518) 13

274. #06 Developmental Delays ADHD, and Autism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in phase … Results The table below lists two topics for which preliminary phase II (for off-label uses of approved … interventions) or phase III data were available for an intervention. … using the company’s “bi-directional” nasal drug delivery technology; OptiNose recently completed a phase

275. Research White Paper Multinational Registries Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/multinational-registries-guide-3rd-ed-addendum-white-paper.pdf
     February 01, 2018 - The terms “phase IV,” “noninterventional,” prospective observational study,” “postmarketing study,” … epidemiological methods shall be used for the analysis of collected data.”30 Other countries use the term “Phase … For example, in Canada, “Phase IV” refers to any postmarketing study of products that have received … “Phase IV” is also commonly used in India and China.

276. Future Research Needs Document (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-cancer-risk-reduction_research.pdf
     October 25, 2010 - Study design Phase I: Identification & Recruitment of Stakeholders Phase I: Stakeholders … to Reduce the Risk of Primary Breast Cancer in Women” • Question and answer discussion Phase IV … : Questionnaire Administration Phase IV: Questionnaire Administration • Web-based • Writable … Genetic polymorphisms in phase I and phase II enzymes and breast cancer risk associated with menopausal … Phase II Trial—Breast Cancer Chemoprevention by Lovastatin. 52. NCT00080756.

277. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/11_peptic_ulcer_potential_high_impact_2012-12-111.pdf
     January 01, 2012 - inclusion are those interventions expected to be within 0–4 years of potential diffusion (e.g., in phase … Results The table below lists the five topics for which (1) preliminary phase III data for drugs and … biologics or phase II data for devices and procedures were available; (2) information was compiled … Phase III trials reported that patients with SBS treated with teduglutide can significantly reduce … Phase 3 Gattex (teduglutide) data highlight potential new treatment for adults with short bowel syndrome

278. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-2007_executive.pdf
     January 01, 2007 - adults receiving antidepressant treatment for a depressive syndrome that either has not responded (acute phase … ) or has relapsed (continuation phase) or recurred (maintenance phase), do alternative antidepressants … the strength of evidence is moderate for the comparative efficacy for treating MDD during the acute phase … Additionally, although most trials maintained the dose used in acute- phase treatment throughout continuation … addressing sequential treatment steps among patients who did not obtain remission with initial acute-phase

279. Disposition of Comments for CER 208 Treatment for Bipolar Disorder in Adults A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-adults-disposition-comments.pdf
     August 07, 2018 - In relative terms, the evidence in maintenance phase for lithium is stronger than for other drugs, … Third, differences in current bipolar phase criteria across studies, ranging from any current phase … recurrence of a mood episode during double‐blind treatment. 303 patients entered the 24‐month DB phase … In the DB phase the modal dose was 25 mg in 44 patients, 37.5 mg in 18 patients, and 50 mg in 3 patients … treatment, maintenance phase treatment, or secondary prevention (when people are first enrolled during

280. Infectious Disease Including HIV/AIDS #09 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/09_infectiousdisease_potential_high_impact_june_2012.pdf
     January 01, 2012 - inclusion are those interventions expected to be within 0–4 years of potential diffusion (e.g., in phase … Results The table below lists the 11 topics for which (1) preliminary phase III data on drugs, phase … In the control arm, 44% of patients achieved an SVR after 48 weeks of IFN/RBV. 4 In a second phase … A phase 2b, safety and efficacy study of Boceprevir in patients coinfected with HIV and Hepatitis … Vertex announces 12-week on-treatment data and SVR4 from phase 2 study of interferon-free (all-oral