Results

Total Results: 1,112 records

Showing results for "phase".

141. Acute Treatments for Episodic Migraine: Surveillance Report 3 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/surveillance-report-3-noninvasive-nonpharma.pdf
     August 01, 2022 - Phase 3 randomized, placebo-controlled, double-blind study of lasmiditan for acute treatment of migraine … Lasmiditan is an effective acute treatment for migraine: a phase 3 randomized study. … Rimegepant for the acute treatment of migraine: subgroup analyses from 3 phase 3 clinical trials by … STOP 301: A Phase 3, open-label study of safety, tolerability, and exploratory efficacy of INP104, … Evaluation of injection-site-related adverse events with galcanezumab: a post hoc analysis of phase

142. Acute Treatments for Episodic Migraine: Surveillance Report 3 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/episodic-migraine-surveillance-report-3.pdf
     August 01, 2022 - Lasmiditan is an effective acute treatment for migraine: a phase 3 randomized study. … Ubrogepant for the acute treatment of migraine: pooled efficacy from ACHIEVE I and ACHIEVE II phase … Rimegepant for the acute treatment of migraine: subgroup analyses from 3 phase 3 clinical trials by … STOP 301: A Phase 3, open-label study of safety, tolerability, and exploratory efficacy of INP104, … Evaluation of injection-site-related adverse events with galcanezumab: a post hoc analysis of phase

143. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tethered-spinal-cord-protocol.pdf
     July 19, 2023 - Lipomyelomeningocele" OR "tight filum syndrome" Recruitment: Completed studies Study Results: All studies Phase … : Phase 2, Phase 3, Phase 4 ICTRP No limits “tethered cord syndrome” OR “tethered spinal cord … lying spinal cord” OR “filum terminale syndrome OR Lipomyelomeningocele” OR “tight filum syndrome” Phase … : Phase 2, Phase 3, Phase 4 Cochrane Database of Systematic Reviews tethered cord syndrome OR tethered

144. Chronic Urinary Retention (CUR) Treatment | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/chronic-urinary-retention/research-protocol
     June 14, 2013 - During the Topic Refinement phase of this project, Key Informants suggested that a review focused on … Key Questions The draft Key Questions (KQs) developed during the Topic Refinement phase were posted … Blind Method/ (118498) Single Blind Method/ (17086) clinical trial/ (476450) clinical trial, phase … i.pt. (12809) clinical trial, phase ii.pt. (20505) clinical trial, phase iii.pt. (7571) clinical … trial, phase iv.pt. (759) controlled clinical trial.pt. (85694) randomized controlled trial.pt.

145. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - inclusion are those interventions expected to be within 0–4 years of potential diffusion (e.g., in phase … Results The table below lists three topics in the system for which (1) preliminary phase III or later … Several phase III trials have been cosponsored by the Cystic Fibrosis Foundation, of Bethesda, MD. … In a randomized, double-blind, placebo-controlled, phase III trial, cosponsored by the Cystic Fibrosis … Vertex Pharmaceuticals initiates phase 3 registration program for VX-770, an oral CFTR potentiator

146. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pulmonary_hi_impact.pdf
     April 01, 2012 - III trials for pharmaceuticals or biotechnologies or in phase II or a trial with some preliminary … The table below lists the three topics for which (1) preliminary phase III were available for drugs … , or phase II, III or later data were available for devices; (2) information was compiled by November … The drug is in several phase III clinical trials cosponsored by the Cystic Fibrosis Foundation. … Vertex Pharmaceuticals initiates phase 3 registration program for VX-770, an oral CFTR potentiator

147. Treatment Resistant Depression Surveillance FINAL (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_surveillance.pdf
     April 01, 2016 - therapy [CBT or interpersonal therapy [IPT]]) differ in efficacy or effectiveness in treating acute phase … treatments compare with pharmacological treatments in efficacy or effectiveness in treating acute-phase … Current Literature Analysis: • We identified a small phase II RCT examining individuals with MDD who … Tier 3: A small phase II RCT (n=60) examined individuals with MDD who had responded to ECT and … RESULTS: Of 90 MDD patients starting the acute phase, 70% responded and 47% remitted to acute ECT.

148. SAMHSA (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/goldstrom.pdf
     January 06, 2017 - process and inclusive of many stakeholders, there needs to be sufficient time for feedback at each phase

149. Protocol Amendment - Safety of Vaccines 030413 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccines-safety-protocol-130325.pdf
     September 18, 2012 - The clinical evaluation of a vaccine typically consists of three phases.8 Phase I studies—which typically … Phase II studies evaluate the immunogenicity of the vaccine and provide preliminary estimates on the … Phase III trials provide the information on a vaccine’s safety and effectiveness that is required to

150. CER 218 Disposition of Comments: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-218-osteoporosis-disposition-comments.pdf
     April 23, 2019 - How ever, this statement is based on data from a small phase 2 study that w as not designed or pow … bone mass after long-term continued, discontinued, and restarting of therapy: a randomized blinded phase … In re-evaluating the evidence from this phase 2 trial on long-term fracture prevention for denosumab … bone mass after long-term continued, discontinued, and restarting of therapy: a randomized blinded phase … In re-evaluating the evidence from this phase 2 denosumab trial on long-term fracture prevention for

151. CER 218 Disposition of Comments: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-disposition-comments.pdf
     April 23, 2019 - How ever, this statement is based on data from a small phase 2 study that w as not designed or pow … bone mass after long-term continued, discontinued, and restarting of therapy: a randomized blinded phase … In re-evaluating the evidence from this phase 2 trial on long-term fracture prevention for denosumab … bone mass after long-term continued, discontinued, and restarting of therapy: a randomized blinded phase … In re-evaluating the evidence from this phase 2 denosumab trial on long-term fracture prevention for

152. Topic 0554 Breastfeeding and Ankyloglossia NSD FINAL SJ (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0653-131114.pdf
     June 14, 2013 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

153. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
     December 01, 2011 - antidepressants differ in their efficacy or effectiveness for preventing relapse (i.e., continuation phase … ) or recurrence (i.e., maintenance phase) when a patient: • continues the drug they initially responded … ) or recurred (maintenance phase), do alternative second- generation antidepressants differ in their … of the 78 possible drug comparisons of second-generation antidepressants for the treatment of acute-phase … For example, for acute-phase MDD we found only 3 effectiveness studies out of 92 head-to-head RCTs.

154. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0107_05-19-2009.pdf
     January 01, 2009 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

155. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0263_12-28-2007.pdf
     January 01, 2007 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

156. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/psoriasis-chronic_research-protocol.pdf
     January 10, 2012 - I (2): complete; Phase II: complete Certolizumabpego l (CDP870) Cimzia ® (injectable) … or metastatic pancreatic cancer, given in combination with gemcitabine Currently available; Phase … active ankylosing spondylitis in adults Currently available; Open-label study in recruitment phase … † Plaque psoriasis development stage is described by: Phase (number of studies): status (if applicable … † Plaque psoriasis development stage is described by: Phase (number of studies): status (if applicable

157. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1312.pdf
     January 01, 2016 - Results The table below lists the eight topics for which (1) preliminary phase III data for drugs, at … least phase II or equivalent data for devices and procedures, or some human data for off-label uses … In March 2013, Intarcia began phase III trials of the ITCA 650/pump system. … This injectable drug competes with other drugs in phase III trials, such as fluocinolone acetonide … Intarcia presents positive ITCA 650 phase 2 study results for type 2 diabetes at EASD.

158. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in phase … Results The table below lists the single topic for which (1) preliminary phase III data for drugs were … Phase III trials on which U.S. … Of the 595 subjects, 173 subjects were treated in Phase 3 SBS studies (134/173 [77%] at the dose of … Phase 3 Gattex (teduglutide) data highlight potential new treatment for adults with short bowel syndrome

159. Disposition of Comments for Evidence Report 221 Behavioral Programs for Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_disposition-comments.pdf
     September 28, 2015 - of intervention following the intensive intervention phase. … of these interventions on A1c is usually greater immediately following the intensive intervention phase … We have meant to use the word support only for the phase of a program extending the DSME (hence our … We did not include studies that were only evaluating the support phase of a program. … maintenance phase of interventions.

160. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1412.pdf
     January 01, 2015 - Results The table below lists the four topics for which (1) preliminary phase III data for drugs, at … least phase II or equivalent data for devices and procedures, or some human data for off-label uses … The company reported in October 2014 that two phase III trials (FREEDOM 1 and FREEDOM 1 high baseline … Available: http://www.intarcia.com/media/press- releases/2014-oct-1-phase-3.html. 63. … Intarcia CEO to present company progress, interim phase 3 data, and key milestones at J.P.