-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antidepressants-2007_executive.pdf
January 01, 2007 - adults receiving antidepressant treatment for a
depressive syndrome that either has not responded
(acute phase … ) or has relapsed (continuation phase)
or recurred (maintenance phase), do alternative
antidepressants … the strength of evidence is moderate for the
comparative efficacy for treating MDD during the acute
phase … Additionally,
although most trials maintained the dose used in acute-
phase treatment throughout continuation … addressing sequential treatment steps among patients
who did not obtain remission with initial acute-phase
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/distributed-network-proof_research.pdf
June 01, 2010 - The first phase included development of a high-level architecture
(Figure 1) and a series of “wire-frame … keeping the Data
Marts simple
Clear and efficient decision-making process during the development phase … polling,
would obviate many of the security concerns that limited the implementation of the
second phase
-
effectivehealthcare-admin.ahrq.gov/products/distributed-network-proof/research
November 01, 2017 - The first phase included development of a high-level architecture ( Figure 1 ) and a series of "wire-frame … Clear and efficient decision-making process during the development phase. … polling, would obviate many of the security concerns that limited the implementation of the second phase
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/registry-of-patient-registries-development_research_0.pdf
February 01, 2012 - trials that must be listed in the registry to include any controlled clinical investigation, other
than Phase … New registries
could post basic information during the launch phase and add more information on data … help a patient decide
whether to consider a
particular trial:
Description of study design
Phase … PDQ Cancer Trials Registry data elements
Category Data Elements
Basic trial information
Phase … New registries would post basic information during the
launch phase and add more information on data
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/09_infectiousdisease_potential_high_impact_june_2012.pdf
January 01, 2012 - inclusion are those interventions expected to be within 0–4 years of potential diffusion (e.g., in
phase … Results
The table below lists the 11 topics for which (1) preliminary phase III data on drugs, phase … In the control arm, 44%
of patients achieved an SVR after 48 weeks of IFN/RBV.
4
In a second phase … A phase 2b, safety and
efficacy study of Boceprevir in patients
coinfected with HIV and Hepatitis … Vertex announces 12-week on-treatment data
and SVR4 from phase 2 study of interferon-free
(all-oral
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/lifecycle-assessment-protocol.pdf
August 23, 2023 - with ISO 14044.10 The method explores the energy, water,
environmental impacts associated with each phase … Cradle is defined as the raw material extraction phase of the product
manufacturing. … Grave describes the end-of-
life phase of a product.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/crohns-disease_disposition-comments.pdf
February 25, 2014 - Literature is for the Phase II trials and perhaps
the rationale is that this is an agent available off … In this review, three clinical trials were used to evaluate
certolizumab pegol (CZP) – two phase II … dose-response studies, and one phase III efficacy
trial. … This dose was evaluated in the phase III efficacy trial for Crohn’s
disease. … Finally, we request
consideration that the review limit its evaluation to only the phase III efficacy
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/restless-legs-future_research.pdf
February 01, 2013 - / (75103)
6 double blind method/ (115894)
7 single blind method/ (16375)
8 clinical trial, phase … i.pt. (12356)
9 clinical trial, phase ii.pt. (19723)
10 clinical trial, phase iii.pt. (7155) … 11 clinical trial, phase iv.pt. (723)
12 controlled clinical trial.pt. (84651)
13 randomized … Patients With RLS Drug: ASP8825|Drug: Placebo
NCT01562743 A Long-Term Extension Trial From Late
Phase … Study of Pramipexole (Sifrol)
in Patients With Idiopathic RLS
Drug: Pramipexole
NCT00349531 A Phase
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1406.pdf
June 01, 2014 - Results
The table below lists the five topics for which (1) preliminary phase III data for drugs were … Although Shire has reported some positive results from phase III clinical
trials, experts commenting … trials for these indications and has two new phase II trials registered.36,37
Diffusion and costs: … In 2012, researchers reported data from a phase II/III trial (n=40) showing that patients receiving … Clinical trials: Preliminary and late-phase clinical trials use Child Depression Rating Scale
(CDRS
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_disposition-comments.pdf
January 15, 2016 - say this, based on knowledge
of basic science and VEGF, steroids only helpful during
proliferative phase … TEP reviewer #5 Introduction 1/25- Recent literature no longer recognizes a plateau
phase. … growth”, would state
that they may have more prolonged growth (or could say
that the proliferative phase … would reword the sentence
that states that “ulceration typically occurs later in the
proliferation phase … . . . “
Ulceration may occur throughout the proliferative phase and
often occurs early.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/alcohol-misuse_research-protocol.pdf
April 28, 2010 - Limits Humans
Clinical Trial; Meta-Analysis; Randomized Controlled Trial; Review; Clinical Trial,
Phase … I; Clinical Trial, Phase II; Clinical Trial, Phase III; Clinical Trial, Phase IV;
Comparative Study … We will retrieve and review the full text of all titles included during the title/abstract review
phase
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/s3.pdf
October 01, 2007 - against Duke.3 However, my
first and most impressive interactions with Harry were during the early phase
-
effectivehealthcare-admin.ahrq.gov/products/survival-quality/research
November 01, 2017 - Menopause: A Systematic Review
Abstract
Jun 05, 2024
Underperformance of Contemporary Phase
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-260-improved-cancer-outcomes-executive-summary_0.pdf
May 01, 2023 - Geriatric
analysis from PRODIGE 20 randomized
phase II trial evaluating bevacizumab +
chemotherapy … combined
with postoperative early oral intake in
elderly patients undergoing hepatectomy
with acute-phase … Oral
nutritional supplements versus a regular diet
alone for body weight loss after
gastrectomy: a phase
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/it-architecture-for-post-marketing-surveillance-arizona-cert.pdf
September 01, 2007 - early on during clinical trials, serious adverse drug effects can still go
undetected during this phase … The FDA monitors for adverse drug events in the
post-marketing phase through the MedWatch program ( … focus is on the
detection of adverse drug events in an outpatient setting and in the post marketing phase … Information flows in the post approval phase
While the FDA and drug companies are able to use broadcast
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/medicine-safety-call-center_research.pdf
September 01, 2007 - early on during clinical trials, serious adverse drug effects can still go
undetected during this phase … The FDA monitors for adverse drug events in the
post-marketing phase through the MedWatch program ( … focus is on the
detection of adverse drug events in an outpatient setting and in the post marketing phase … Information flows in the post approval phase
While the FDA and drug companies are able to use broadcast
-
effectivehealthcare-admin.ahrq.gov/products/COVID-19-pharmaceutical-treatments/rapid-research
March 01, 2024 - Phase 2/3 Trial of Molnupiravir for Treatment of Covid-19 in Nonhospitalized Adults. … A phase 2a clinical trial of molnupiravir in patients with COVID-19 shows accelerated SARS-CoV-2 RNA … Pfizer Announces Additional Phase 2/3 Study Results Confirming Robust Efficacy of Novel COVID-19 Oral … Phase 2 dose-ranging study of the virologic efficacy and safety of the combination COVID-19 antibodies
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2022-update-executive-summ.pdf
January 01, 2022 - since we will not complete updated RoB assessment for all 389
studies from the previous report in this phase
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
April 01, 2015 - For
example, a patient newly diagnosed with MS in the novice
phase of learning about MS would likely … After excluding articles at the title
and abstract phase, full texts of 198 articles were reviewed … Furthermore, some patients with
RRMS never transition to a clear secondary progressive
phase. … a first clinical event
suggestive of multiple sclerosis: 5-year active treatment extension
of the phase … Long-term follow-
up of a phase 2 study of oral teriflunomide in relapsing multiple
sclerosis: safety
-
effectivehealthcare-admin.ahrq.gov/products/deliberative-methods/research-2013
January 01, 2019 - The process includes educational and discussion-based components (i.e., the “information phase” and the … “deliberation phase,” Goodin, 2008). … In the information phase, participants are given accurate, balanced information about relevant positions … In the deliberation phase, participants engage in dialogue and the active exchange of reasons and justifications