Results

Total Results: 1,077 records

Showing results for "phase".

21. A Process for Robust and Transparent Rating of Study Quality: Phase 1 | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/quality-rating/research
    November 01, 2017 - Evidence Reports A Process for Robust and Transparent Rating of Study Quality: Phase … : A Process for Robust and Transparent Rating of Study Quality: Phase … Purpose To complete the first phase of a project to develop such a methodology, we aimed to examine … Project Timeline A Process for Robust and Transparent Rating of Study Quality: Phase 1 May 4, 2010 … Research Report: A Process for Robust and Transparent Rating of Study Quality: Phase

22. Future Research Needs for Strategies To Reduce Cesarean Birth in Low-Risk Women | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/cesarean-birth/research
    December 01, 2019 - Data sources In Phase 1, stakeholders participated in a teleconference and then a Web-based survey … In Phase 2, stakeholders participated in one conference call and completed three Web-based surveys to … In Phase 1, stakeholders generated a "snowballed" list of 47 research questions and 17 methodologic recommendations … In Phase 2, stakeholders worked from the snowballed list to prioritize research needs. … In Phase 3, the Evidence-based Practice Center investigators developed recommendations for optimal study

23. Medicare-Medication-Use Research (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/medicare-medication-use_research.pdf
    April 01, 2014 - .17 In addition, the existence of a Part D coverage gap before reaching the catastrophic coverage phase … coverage limit (pre-ICL), initial coverage limit (ICL), and catastrophic coverage phase us- ing the … Claims were submitted for the highest average number of unique medications during the pre-ICL phase … The pre- ICL phase showed similar trends to the deductible phase, with all categories having approximately … , meaning some people have no days in this phase before reaching the pre-ICL phase.29 Many plans also

24. Arthritis and Nontraumatic Joint Disease (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - Results The table below lists the three topics for which (1) preliminary phase III data for drugs were … Five phase III trials on secukinumab for treating AS are ongoing. … Five phase III trials on lesinurad have been completed, and two phase III extension trials are ongoing … Four phase III trials on secukinumab for treating PsA are ongoing. … In the phase III MEASURE 1 trial, patients (n=371) with active AS who were intolerant of or did not

25. Vaginal Birth After Cesarean: Developing and Prioritizing a Future Research Agenda (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cesarean-birth-future_research.pdf
    August 09, 2012 - We invited 11 stakeholders to participate in the phase 2 Delphi process. … Gaps Phase IIa Stakeholder identification of key topics for prioritization Phase Ilb Delphi … Of the 16 stakeholders interviewed in phase 1, 11 were invited to take part in phase 2 of our study. … Phase 2 Questions for the first round of the phase 2 prioritization were based on the categories and … themes (listed above) that were identified in phase 1.

26. Arthritis and Nontraumatic Joint Disease (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - Results The table below lists the single topic for which (1) at least preliminary phase III data were … In phase III clinical trials, significantly more patients treated with lesinurad in combination with … Four phase III trials on lesinurad have been completed, and two phase III extension trials are ongoing … In two replicate phase III trials, CLEAR 1 (n=603) and CLEAR 2 (n=610), patients received lesinurad … Ardea Biosciences announces positive top-line results from phase 2b combination study of RDEA594

27. Distributed Ambulatory Research in Therapeutics Network (DARTNet): Informing Practice and Improving Depression Care | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/depression-care-distributed-networks/abstract
    December 01, 2019 - This will be conducted in three phases: Phase 1: Claims Database Study Utilization - Conduct population-based … Phase 2: DARTNet EHR Database Study The second phase will compare the findings of the claims database … Phase 3: DARTNet Point-of-Care Data Collection and Practice Facilitation The third phase of the project

28. BLUEPRINT FOR A FUTURE DISTRIBUTED RESEARCH NETWORK (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/distributed-network-blueprint_research.pdf
    June 01, 2010 - Functionality (Phase 1) In phase 1, functionality should include the ability to securely distribute … Phase 2: Network Expansion The next phase, which should follow as soon as practicable, should expand … Functionality (Phase 2) In phase 2, the flexibility of the menu-driven interface should be expanded … Phase 3: Network Maturation The final phase of network development could be completed within four to … Phase 1: Network Initiation 2.3.2. Phase 2: Network Expansion 2.3.3.

29. Comparative Effectiveness of Second Generation Antidepressants in the Pharmacologic Treatment of Adult Depression – An Update to a 2007 Report | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/antidepressants-update/research-protocol
    December 01, 2019 - ) or recurrence (i.e., maintenance phase) when a patient continues the drug they initially responded … of depression using these second generation antidepressants – where KQ1 addresses the acute phase and … KQ2 the continuation or maintenance phase. … Definition of Terms Acute Phase: first phase of depression management, usually 6 to 12 weeks in length … Continuation Phase: second phase of depression management during which the treatment goal is continued

30. DARTNet Summary Report (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/distributed-network-ambulatory-therapeutics_research.pdf
    July 01, 2009 - We used the Ingenix/ICHIS Impact database for Phase 1. … Phase 2 was a replication of the same study using DARTNet data. … We used the Ingenix/ICHIS Impact database for Phase 1. … Phase 2 was a replication of the same study using DARTNet data. … Phase 2 results are summarized as follows.

31. A Framework To Facilitate the Use of Systematic Reviews and Meta-analyses in the Design of Primary Research Studies | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/primary-research-design/research
    January 01, 2019 - Phase 1 involved a focused literature search to identify existing frameworks and processes that have … In phase 2, we convened a multidisciplinary group with varied expertise to develop a stepwise framework … In phase 3, we identified two systematic reviews and applied this framework to their results. … Phase 4 invited external opinions from additional experts to further refine the framework.

32. Evidence Report on the (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
    July 13, 2011 - antidepressants differ in their efficacy or effectiveness for preventing relapse (i.e., continuation phase … of depression using these second generation antidepressants – where KQ1 addresses the acute phase … and KQ2 the continuation or maintenance phase. … Definition of Terms Acute Phase: first phase of depression management, usually 6 to 12 weeks in length … Continuation Phase: second phase of depression management during which the treatment goal is continued

33. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1512.pdf
    November 01, 2016 - Results The table below lists the single topic for which (1) preliminary phase III data for drugs were … Three phase III trials are ongoing. … from a completed phase III trial, M12-665.10 That trial (n=872) is evaluating the change in pain, … A global phase 3 study to evaluate the safety and efficacy of elagolix in subjects with moderate … Elagolix treatment for endometriosis-associated pain: Results from a phase 2, randomized, double-

34. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1506.pdf
    November 01, 2016 - Results The table below lists the single topic for which (1) preliminary phase III data for drugs were … Four phase III trials are ongoing. … According to a manufacturer press release, positive preliminary results reported from one phase III … A global phase 3 study to evaluate the safety and efficacy of elagolix in subjects with moderate … Elagolix treatment for endometriosis-associated pain: Results from a phase 2, randomized, double-

35. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - Results The table below lists the single topic for which (1) preliminary phase III data for drugs (or … II/III or phase III clinical trials. … The manufacturer considers the phase I data encouraging enough that it plans to advance directly to … a phase III trial later this year. … U.S. and European investigators are leading phase II and II/III clinical trials studying intranasal

36. Testing the Predictive Validity of Strength of Evidence Grades | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/grades-predictive-values/abstract
    December 01, 2019 - The project consisted of two main phases: Phase 1: Comparison of Effects as Evidence Evolves From … Phase 2: Assessing the Predictive Validity of Strength of Evidence Grades: A Meta-Epidemiological Study … The goal of this phase is to address the three objectives of this methods project. … To address the first objective, we used data gathered through Phase 1 to calculate the proportion of

37. Infectious Disease Including HIV/AIDS #09 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1512.pdf
    January 28, 2016 - A number of other manufacturers also have all-oral HCV DAA regimens in phase II or phase III development … Grazoprevir/elbasvir is being evaluated in several phase II and III trials for treating chronic HCV … Four additional phase III trials on grazoprevir/elbasvir are ongoing. … In a phase III study, patients with HCV genotype 1 infection achieved an average SVR12 rate of 92%. … In the phase III ION studies, patients achieved SVR12 rates of 94% to 99%.

38. Hypofractionated Radiation Therapy for Localized Prostate Cancer (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-key-question.pdf
    December 19, 2023 - Cruickshank C, Hassan S, Pugh J, Dearnaley DP, Hall E; 10-Year efficacy and co-morbidity outcomes of a phase … radiotherapy for prostate cancer (PACE-B): 2-year toxicity results from an open-label, randomised, phase … Patient-Reported Outcomes in the Acute Phase of the Randomized Hypofractionated Irradiation for Prostate … Analysis of the Prostate Cancer Study-5, a Groupe de Radio-Oncologie Génito-Urinaire de Quebec Led Phase … for High-Risk Prostate Cancer Patients (CHIRP): 24-Month Patient-Reported Outcomes of the Randomized Phase

39. Advancing Measurement of Patient-Centered Communication in Cancer Care | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/cancer-communication/research
    November 01, 2017 - Structured Abstract Background This is a second-phase project sponsored by AHRQ and the National … Phase 1 developed a framework for measuring patient- centered communication (PCC) in cancer care, including … Objectives The goal of Phase 2 was to refine the Phase 1 framework; identify, develop, and test PCC

40. Hypofractionated Radiation Therapy for Localized Prostate Cancer | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/hypofractionated-radiation-therapy
    June 01, 2024 - Cruickshank C, Hassan S, Pugh J, Dearnaley DP, Hall E; 10-Year efficacy and co-morbidity outcomes of a phase … radiotherapy for prostate cancer (PACE-B): 2-year toxicity results from an open-label, randomised, phase … Patient-Reported Outcomes in the Acute Phase of the Randomized Hypofractionated Irradiation for Prostate … Analysis of the Prostate Cancer Study-5, a Groupe de Radio-Oncologie Génito-Urinaire de Quebec Led Phase … for High-Risk Prostate Cancer Patients (CHIRP): 24-Month Patient-Reported Outcomes of the Randomized Phase