Results

Total Results: 1,077 records

Showing results for "phase".

161. Safety of Vaccines Used for Routine Immunization in the United States | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/safety-vaccines/protocol
     January 01, 2021 - 4 or 5 or 6 or 7 or 8 or 9 or 10 or 11 or 12 or 13 (152174) ("clinical trial" or "clinical trial, phase … i" or "clinical trial, phase ii" or clinical trial, phase iii or clinical trial, phase iv or controlled … randomized controlled trial").pt. or double-blind method/ or clinical trials as topic/ or clinical trials, phase … i as topic/ or clinical trials, phase ii as topic/ or clinical trials, phase iii as topic/ or clinical … trials, phase iv as topic/ or controlled clinical trials as topic/ or randomized controlled trials as

162. Horizon-Scan Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/horizon-scan_research-protocol.pdf
     December 01, 2011 - Is it transitioning from one phase to another? If so, select. b. … Is it transitioning from one phase to another? If so, select. b. … Is it transitioning from one phase to another? If so, select. b. … for track-only; interventions with some preliminary phase III or later phase efficacy data are considered … Phase of Development and Comment 9.

163. Enzyme Replacement Therapy for Lysosomal Storage Disorders | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/lysosomal-storage-diseases-therapies/research-protocol
     December 01, 2020 - We also sought prospective phase I or II nonrandomized studies that included patient subgroups with specific … If higher-level studies (RCTs, prospective phase I and II) were not available, case series (single-arm … not assess study quality or the overall strength of the evidence” During the Topic Refinement phase … There also were a number of prospective phase I and II clinical studies that complemented the RCTs. … validity, we made a decision to compile the RCTs in the evidence map, supplementing them with prospective phase

164. Therapies for Children with Autism Spectrum Disorders—Research Protocol Document | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/autism/research-protocol
     December 01, 2019 - we revised the key questions to clarify the emphasis on examining the correlation of early treatment phase … KQ3: Are there any identifiable changes early in the treatment phase that predict treatment outcomes … KQ4: What is the evidence that effects measured at the end of the treatment phase predict long term … criteria developed based on our understanding of the literature developed during the topic refinement phase … Weekly during the review phase of the study, the Project Coordinator will report the number of abstracts

165. Newer Medications for Lower Urinary Tract Symptoms (LUTS) Associated with Benign Prostatic Hyperplasia (BPH) | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/prostatic-hyperplasia-medications/research-protocol
     December 01, 2019 - adrenergic agonist Increases bladder capacity by relaxing the bladdersmooth muscle during the storage phase … random allocation/ double blind method/ single blind method/ clinical trial/ clinical trial, phase … clinical trial, phase ii.pt. clinical trial, phase iii.pt. clinical trial, phase iv.pt. … Effects and Adverse Reactions"/ exp Adverse Drug Reaction Reporting Systems/ exp Clinical Trials, Phase … Effects and Adverse Reactions"/ exp Adverse Drug Reaction Reporting Systems/ exp Clinical Trials, Phase

166. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in phase … Results The table below lists the one topic for which (1) preliminary phase III data were available; … These topics were ineligible for consideration in this report because no phase III data were available

167. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - inclusion are those interventions expected to be within 0–4 years of potential diffusion (e.g., in phase … priority area this time (among the 11 topics being tracked as of May 18, 2013) for which (1) preliminary phase … The 6-month buprenorphine implant completed phase III trials, one of which was funded by the National

168. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0416_02-18-2011.pdf
     January 01, 2011 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

169. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0264_01-14-2008.pdf
     January 01, 2008 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

170. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0477_11-01-2011.pdf
     January 01, 2011 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

171. TND-0543_05-24-2013 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0543_05-24-2013.pdf
     January 01, 2013 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

172. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0407_01-20-2011.pdf
     January 01, 2011 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

173. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0496_12-30-2011.pdf
     January 01, 2011 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

174. Topic 0523 Muscle Invasive Bladder Cancer NSD FINAL_SJ (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0620_131115.pdf
     March 13, 2013 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

175. Statistical Design and Analytic Considerations for N-of-1 Trials (Chapter 4) | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/n-1-trials/research-2014-1
     August 01, 2019 - After establishing a predictable baseline pattern of data, one examines the data within each phase to … assess the performance and potentially to extrapolate to the next phase. … Assessment involves: (1) level, the mean for the data in a phase; (2) trend, the slope of the line of … best fit in a phase; (3) variability of the data around this line; (4) immediacy of the effect, the … had an effect by changing the outcome from phase to phase.

176. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1412.pdf
     February 01, 2015 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in phase … Results The table below lists the two topics for which (1) preliminary phase III data for drugs were … this period, primarily due to failure to meet stated endpoints or demonstrate treatment efficacy in phase … and two beta-amyloid precursor protein site–cleaving enzyme (BACE) inhibitors, currently in late-phase … The latter cooperative sponsors the largest ongoing trial, a phase II/III trial investigating intranasal

177. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in phase … Results The table below lists the one topic for which (1) preliminary phase III data for drugs were … Phase III trials conducted to obtain FDA approval reported that patients with SBS treated with teduglutide … Of the 566 subjects, 173 subjects were treated in Phase 3 SBS studies (134/173 [77%] at the dose of … Phase 3 Gattex (teduglutide) data highlight potential new treatment for adults with short bowel syndrome

178. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1512.pdf
     December 01, 2015 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in phase … Results The table below lists the four topics for which (1) preliminary phase III data for drugs or … Recently completed unphased, phase II, and phase IV clinical studies reported that daily oral zonisamide … In a phase III trial sponsored by the University of Pittsburgh (Pittsburgh, PA) and its affiliated … , a University of Pittsburgh (Pittsburgh, PA)-based research group reported results from a larger phase

179. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/head-neck-cancer_disposition-comments.pdf
     May 27, 2010 - The reference is: First results of a phase III multicenter randomized controlled trial of intensity … All three randomized studies, as well as all phase II-like and retrospective comparisons, report improved … Besides careful phase I-II studies of dose escalation, a policy of delivering higher doses using IMRT … In addition, two phase III RTOG trials (0522 and 0234) have 3DRT and IMRT treatment populations which … Besides careful phase I-II studies of dose escalation, a policy of delivering higher doses using

180. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0129_07-13-2009.pdf
     January 01, 2009 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase