Results

Total Results: 1,077 records

Showing results for "phase".

141. CER 218 Disposition of Comments: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-disposition-comments.pdf
     April 23, 2019 - How ever, this statement is based on data from a small phase 2 study that w as not designed or pow … bone mass after long-term continued, discontinued, and restarting of therapy: a randomized blinded phase … In re-evaluating the evidence from this phase 2 trial on long-term fracture prevention for denosumab … bone mass after long-term continued, discontinued, and restarting of therapy: a randomized blinded phase … In re-evaluating the evidence from this phase 2 denosumab trial on long-term fracture prevention for

142. Topic 0554 Breastfeeding and Ankyloglossia NSD FINAL SJ (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0653-131114.pdf
     June 14, 2013 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

143. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
     December 01, 2011 - antidepressants differ in their efficacy or effectiveness for preventing relapse (i.e., continuation phase … ) or recurrence (i.e., maintenance phase) when a patient: • continues the drug they initially responded … ) or recurred (maintenance phase), do alternative second- generation antidepressants differ in their … of the 78 possible drug comparisons of second-generation antidepressants for the treatment of acute-phase … For example, for acute-phase MDD we found only 3 effectiveness studies out of 92 head-to-head RCTs.

144. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0263_12-28-2007.pdf
     January 01, 2007 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

145. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0107_05-19-2009.pdf
     January 01, 2009 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

146. Nitrous Oxide for the Management of Labor Pain | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/labor-nitrous-oxide/research-protocol
     December 01, 2019 - Additional discussions with the TEP following the public comment phase were also critical in shaping … The majority of comments received during the public comment phase were judgments regarding the effectiveness … Analytic Framework Several comments were received during the public comment phase and TEP discussions … criteria developed based on our understanding of the literature developed during the topic refinement phase … Weekly during the review phase of the study, the Project Coordinator will report the number of abstracts

147. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/psoriasis-chronic_research-protocol.pdf
     January 10, 2012 - I (2): complete; Phase II: complete Certolizumabpego l (CDP870) Cimzia ® (injectable) … or metastatic pancreatic cancer, given in combination with gemcitabine Currently available; Phase … active ankylosing spondylitis in adults Currently available; Open-label study in recruitment phase … † Plaque psoriasis development stage is described by: Phase (number of studies): status (if applicable … † Plaque psoriasis development stage is described by: Phase (number of studies): status (if applicable

148. Diabetes Mellitus (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1312.pdf
     January 01, 2016 - Results The table below lists the eight topics for which (1) preliminary phase III data for drugs, at … least phase II or equivalent data for devices and procedures, or some human data for off-label uses … In March 2013, Intarcia began phase III trials of the ITCA 650/pump system. … This injectable drug competes with other drugs in phase III trials, such as fluocinolone acetonide … Intarcia presents positive ITCA 650 phase 2 study results for type 2 diabetes at EASD.

149. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - inclusion are those interventions expected to be within 0–3 years of potential diffusion (e.g., in phase … Results The table below lists the single topic for which (1) preliminary phase III data for drugs were … Phase III trials on which U.S. … Of the 595 subjects, 173 subjects were treated in Phase 3 SBS studies (134/173 [77%] at the dose of … Phase 3 Gattex (teduglutide) data highlight potential new treatment for adults with short bowel syndrome

150. Medical Tests - White Paper Series | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/medical-tests-series/overview
     August 01, 2019 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

151. Disposition of Comments for Evidence Report 221 Behavioral Programs for Diabetes Mellitus (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_disposition-comments.pdf
     September 28, 2015 - of intervention following the intensive intervention phase. … of these interventions on A1c is usually greater immediately following the intensive intervention phase … We have meant to use the word support only for the phase of a program extending the DSME (hence our … We did not include studies that were only evaluating the support phase of a program. … maintenance phase of interventions.

152. Diabetes Mellitus (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1412.pdf
     January 01, 2015 - Results The table below lists the four topics for which (1) preliminary phase III data for drugs, at … least phase II or equivalent data for devices and procedures, or some human data for off-label uses … The company reported in October 2014 that two phase III trials (FREEDOM 1 and FREEDOM 1 high baseline … Available: http://www.intarcia.com/media/press- releases/2014-oct-1-phase-3.html. 63. … Intarcia CEO to present company progress, interim phase 3 data, and key milestones at J.P.

153. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/01_-arthritis_potential_high_impact_june_2012.pdf
     January 01, 2012 - Results The table below lists the seven topics for which (1) preliminary phase III or later phase data … Expert comments led to designation of one RA therapy in phase III development as having high potential … In the most recent phase III trials, tofacitinib was administered twice daily in 5 and 10 mg doses. … In phase III trials, patients treated with tofacitinib demonstrated improvements in signs and symptoms … Pfizer's tofacitinib meets endpoints in final phase III trials.

154. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0161_09-01-2009.pdf
     January 01, 2009 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

155. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0288_03-10-2008.pdf
     January 01, 2008 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

156. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0136_07-21-2009.pdf
     January 01, 2009 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

157. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0456_07-27-2011.pdf
     January 01, 2011 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

158. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0064_11-23-2008.pdf
     January 01, 2008 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

159. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0119_06-17-2009.pdf
     January 01, 2009 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase

160. Topic 0548 Comparative Effectiveness of Treatments for MDD NSD FINAL SJ (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0647-13114.pdf
     June 21, 2013 - populations, interventions, comparators, and outcomes, will be further developed in the refinement phase