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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/prevention-of-human-immunodeficiency-virus-hiv-infection-pre-exposure-prophylaxis
January 13, 2022 - What are the benefits of pre-exposure prophylaxis (PrEP) in persons … What is the diagnostic accuracy of provider or patient risk assessment tools in identifying persons at … What is the risk of infection with antiretroviral drug–resistant HIV in persons using PrEP, and what … of interest are defined by age, sex, gender identity, race and ethnicity, and HIV risk category
Persons … randomized, controlled trials are not available
* Including pregnant and breastfeeding persons
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/syphilis-infection-screening-2004
July 15, 2004 - at Increased Risk
The USPSTF strongly recommends that clinicians screen persons at increased risk … A
Asymptomatic Persons, Not at Increased Risk
The USPSTF recommends against routine screening … of asymptomatic persons who are not at increased risk for syphilis infection. … The USPSTF concludes that the benefits of screening persons at increased risk for syphilis infection … The optimal screening interval in average- and high-risk persons has not been determined.
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www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/vitamin-d-calcium-combined-supplementation-primary-prevention-falls-fractures-communitydwelling-adults
December 17, 2024 - This corresponds to an ARD of 2 fewer major osteoporotic fractures per 1,000 persons supplemented (95% … This corresponds to an ARD of 2 fewer nonvertebral fractures per 1,000 persons treated (95% CI, from … This corresponds to an ARD of 3 fewer fractures per 1,000 persons supplemented (95% CI, from 7 fewer … This corresponds to an ARD of 2 fewer deaths per 1,000 persons supplemented (95% CI, from 4 fewer to … Vitamin D supplementation and fracture incidence in elderly persons.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/uhtgkZVs_bpNJ4_G4fXUay
March 01, 2014 - Screening
should be discontinued once a person has not smoked for 15 years
or develops a health problem … Screening should be discontinued once a
person has not smoked for 15 years or develops a health
problem … The magnitude of benefit to the person depends
on that person’s risk for lung cancer because those who … Screening should be discontinued
once the person has not smoked for 15 years. … Harms were measured as the
number of total LDCT screenings per 100 000 persons
and per person, number
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www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-appendix-vii-criteria-assessing-external-validity-generalizability-individual-studies
July 01, 2017 - rate of outcomes in the study could be greater or less than what might be expected in asymptomatic persons … The harms observed in the study could be greater or less than what might be expected in asymptomatic persons … comorbid conditions in the study population does not represent the frequency likely to be encountered in persons … Stage or severity of disease: the selection of subjects for the study includes persons at a disease stage … that is earlier or later than would be found in persons who are candidates for the preventive service
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/asymptomatic-bacteriuria-in-adults-screening
December 28, 2017 - who have a compromised immune system
Persons who have a catheter, urinary stent, or nephrostomy tube … or other organ transplant; patients on kidney dialysis
Pregnant women with sickle cell disease
Persons … care for treatment or followup of conditions affecting the urinary tract (e.g., prostate cancer)
Persons … being tested in preparation for urological procedures
Persons with spinal cord injuries
Studies … conducted exclusively among persons who are institutionalized or hospitalized
Interventions
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions
July 12, 2018 - Print
Final Research Plan
Tobacco Smoking Cessation in Adults, Including Pregnant Persons … including pregnant women who currently smoke
Reviews limited to:
Children and adolescents
Persons
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/9UeCh-u72auj6MqBNNVJt9
May 01, 2020 - years), adolescents (aged 12 to 17 years), and young adults (aged 18 to 25
years), including pregnant persons … It does not apply to persons who have a history of regular or harmful illicit drug use or who have been … adolescents and adults
• Interventions for tobacco smoking cessation in adults, including pregnant persons
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/human-immunodeficiency-virus-hiv-infection-screening-1996
January 01, 1996 - against routine HIV screening in persons without identified risk factors. … A minority of seropositive persons abstain completely from sex or drug use after diagnosis. … persons—United States, 1992-1994. … Forecasts of the costs of medical care for persons with HIV:1992-1995. … The duration of zidovudine benefit in persons with asymptomatic HIV infection.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/diabetes-mellitus-type-2-in-adults-screening-2008
June 15, 2008 - Persons with these symptoms or conditions should be tested for diabetes. … Suggestions for Practice Regarding the I Statement: In persons with blood pressure of 135/80 mm Hg or … should be lower for persons who have type 2 diabetes mellitus than for those who do not. … The USPSTF recommends intensive interventions for obese persons who desire to lose weight. … persons.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/skin-cancer-counseling
March 20, 2018 - Persons with a compromised immune system (eg, persons living with HIV, persons who have received an organ … Implementation
Interventions included tailored mailings, print materials, and in-person … Health professionals providing in-person counseling included primary care clinicians and health educators … One trial used a 1-day, in-person parent education session with a children's video, print materials, … An in-person counseling intervention targeting adolescents and involving clinicians and health educators
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/mggnaKHr496c8QCgHe9-tm
May 01, 2021 - The evi-
dence review did not include populations at very high risk for COPD
such as persons with α-1 … less than 0.70
confirms the presence of persistent airway obstruction and a diag-
nosis of COPD in persons … • It does not apply to populations at very high risk for COPD, such as persons with α-1 antitrypsin … One large randomized clinical trial (SUMMIT; n = 16 590) in
persons with or at risk for cardiovascular … • The harms of screening in and treatment of persons with asymp-
tomatic or minimally symptomatic COPD
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/skin-cancer-counseling
March 20, 2018 - Persons with a compromised immune system (eg, persons living with HIV, persons who have received an organ … Implementation
Interventions included tailored mailings, print materials, and in-person … Health professionals providing in-person counseling included primary care clinicians and health educators … One trial used a 1-day, in-person parent education session with a children's video, print materials, … An in-person counseling intervention targeting adolescents and involving clinicians and health educators
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/genital-herpes-screening-november-2016
December 20, 2016 - Among persons who have a symptomatic first outbreak, 70% to 90% will have at least 1 more symptomatic … Although the risk of transmission is higher during a symptomatic outbreak, persons with genital herpes … There is currently no cure for genital herpes; once infection has occurred, the virus remains in a person … Serologic HSV tests may be clinically useful for persons with persistent undiagnosed genital symptoms … Diagnostic testing, however, in persons with recurrent atypical genital symptoms may be helpful.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/carotid-artery-stenosis-screening-1996
January 01, 1996 - Asymptomatic adults
There is insufficient evidence to recommend for or against screening asymptomatic persons … Population-based cohort studies have established that persons with carotid artery stenosis are at increased … subsequent stroke, myocardial infarction (MI), and death. 9 , 10 The risk of stroke is greatest for persons … No study has specifically compared a strategy of screening and early intervention in asymptomatic persons … A number of studies have examined whether interventions in asymptomatic persons can reduce the subsequent
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/chronic-kidney-disease-screening
July 13, 2023 - What is the effectiveness of interventions aimed at reducing disparities in persons with CKD? … diabetes mellitus or hypertension
KQs 1–3:
Patients with known CKD or symptoms of CKD
Pregnant persons … KQs 4–8:
Patients with non-screen-detected CKD stages 4 to 5
Pregnant persons
Interventions … Guidelines on evaluation of kidney disease in persons with diabetes mellitus and hypertension already … Some comments suggested expansion of the treatment population to persons with later-stage CKD (CKD stages
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/prevention-of-human-immunodeficiency-virus-hiv-infection-pre-exposure-prophylaxis
August 22, 2023 - No trial enrolled pregnant persons or persons younger than 18 years. … , P = .01) and those who took more than 15 pills per month (0 vs 8.1 per 100 person-years, P = .004 … which 100% of patients had completed 48 weeks and 50% had completed 96 weeks): 0.16 vs 0.34 per 100 person-years … 95% CI, 0.19-1.14) c HIV infection at 96 wk (all patients had completed 96 wk): 0.16 vs 0.30 per 100 person-years … and 1.6 vs 2.0 per 100 person-years
Consistent; precise No reporting bias detected
Good
Trial
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/statin-use-in-adults-preventive-medication
November 05, 2020 - initiating statins for primary prevention at different cardiovascular risk thresholds on the number of persons … In persons with similar assessed cardiovascular risk, how does use of statins for primary prevention … e.g., myocardial infarction, angina, revascularization, CVA, or transient ischemic attack), including persons … as a factor defining subgroups of interest and added a contextual question on how use of statins in persons
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/hepatitis-b-virus-infection-screening
March 14, 2019 - What is the accuracy of tools for identifying persons with chronic HBV infection? … In persons with serologic evidence of HBV infection (positive test results for the antibody to hepatitis … living with HIV or hepatitis C virus infection, persons who have been previously treated for HBV infection … , and other special populations (e.g., persons undergoing hemodialysis or an organ transplant) … who inject drugs, men who have sex with men, or persons with sexually transmitted diseases)
KQs
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/healthy-lifestyle-and-physical-activity-for-cvd-prevention-adults-without-known-risk-factors-behavioral-counseling
July 26, 2022 - reclining while watching television or using a computer. 1
Primary care clinicians can deliver in-person … ; in 17 trials, Asian persons, Black persons, Hispanic/Latino persons, or Native American/American Indian … Delivery mode varied widely; 52.9% of trials included at least 1 in-person counseling session, whereas … research into effective primary care–community connections and clinical training to support delivering in-person … Future research should identify best practices to improve clinician skills in delivering in-person behavioral