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9161. Archived: Evidence Summary: Carotid Artery Stenosis: Screening | United States Preventive Services Taskforce
      www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/carotid-artery-stenosis-screening-july-2014
      July 08, 2014 - In the ACAS 33 , 1.2% of patients (5 of 414) who had angiography had strokes; 1 patient died subsequently … Safety of stenting and endarterectomy by symptomatic status in the Carotid Revascularization Endarterectomy … Protected carotid-artery stenting versus endarterectomy in high-risk patients. … Carotid endarterectomy in Oklahoma Medicare beneficiaries: patient characteristics and outcomes. … inferior in symptomatic patients.

9162. breast-biopsy-update-130920 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_research-protocol.pdf
      September 20, 2013 - However, the impact aspects of biopsy technique have on test performance and safety are not clear. … has been identified as a topic of interest for the updated review, is used mainly in this subset of patients … Retrospective case studies (“case series”12) and other studies sampling patients on the basis of outcomes … We will evaluate studies (or subgroups of studies) of elderly women (operationally defined as patients … Key Informants Key Informants are the end-users of research, including patients and caregivers, practicing

9163. Methods-Guidance-Topics Methods (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topics_methods.pdf
      January 01, 2010 - Regulatory agencies may be interested in questions of safety and effectiveness. … to improve health outcomes (morbidity, mortality) and quality of life, improve decisionmaking for patient … Whether the guidance would promote the best possible improvement in public health or well-being and/or patient … consumer/patient organizations Employers and business groups Federal and State partners Health care … What specific patient characteristics may affect outcomes?

9164. Research Protocol: Clostridium difficile Infection Update (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
      December 23, 2014 - CDI recurs in 15-35 percent of patients with one previous episode and 33-65 percent of patients who … In patients with relapse/recurrent CDI. … alone Patients not suspected to have CDI; healthy patients Intervention Diagnostic tests for toxin … rates CDI mortality rates Harms, such as increase in organism resistance, hospital cleaning staff safety … In addition, we are including studies that are conducted in patients at risk for CDI.

9165. Comparative Effectiveness of β-Adrenergic Antagonists on the Risk of Rehospitalization in Adults with Heart Failure (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-rehospitalization_research.pdf
      November 01, 2007 - about the outcomes, clinical effectiveness, safety, and appropriateness of health care items and services … β-blockers in the setting of heart failure is not clinically indicated,(25) if we observed that a patient … for a different β-blocker before the projected end date for an existing β-blocker prescription, the patient … membership gaps of 60 day or more in addition to an active pharmacy drug benefit (i.e., no missing monthly indicators … Any patient who dies during the index hospitalization was excluded.

9166. VitaminD, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults: Evidence Report and Systematic Review for the USPSTF (pdf file)
      www.uspreventiveservicestaskforce.org/home/getfilebytoken/Yc24U4wMLXGoqE5NjwRVA6
      April 17, 2018 - 15):1600-1612. doi:10.1001/jama.2017.21640 Editorial page 1552 Related article page 1592 and JAMA Patient … the key questions that the review will address to allow the USPSTF to evaluate the effectiveness and safety … Calcium, or Both With Placebo or Control Favors Supplement Favors Control Fracture Type No. of Patients … Comparing Calcium or Both Vitamin D and Calcium With Placebo Favors Supplement Favors Placebo No. of Patients

9167. Organisation (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-radiation_appendixes.pdf
      June 16, 2008 - Efficacy and safety of carbon ion radiotherapy in bone and soft tissue sarcomas. … Results in 67 patients. … Influence of patient age on biochemical freedom from disease in patients undergoing conformal proton … Patient tolerance of rectal balloons in conformal radiation treatment of prostate cancer. … Patient study of in vivo verification of beam delivery and range, using positron emission tomography

9168. Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force (pdf file)
      www.uspreventiveservicestaskforce.org/home/getfilebytoken/DYFdTVu-UY3h7CWGdA7Zkh
      July 20, 2021 - Editorial page 1943 Multimedia Related articles pages 1965 and 1998 and JAMA Patient Page page 2026 … Summary of Safety and Effectiveness Data for Cologuard. US Food and Drug Administration. … Colorectal Cancer Screening Programme in Spain: results of key performance indicators after five rounds … Patient-reported adverse events after colonoscopy in Norway. … Quality and safety of screening colonoscopies Clinical Review & Education US Preventive Services Task

9169. Layout 1 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_executive.pdf
      October 01, 2010 - Key Question 6: In patients with CF, how are efficacy, effectiveness, safety, or adverse events impacted … Key Question 7: In patients with CF, how do the efficacy, effectiveness, safety, or adverse events of … Subgroup analyses were conducted to assess the effect of treatment duration and patient pubertal status … In an analysis of trials with individual patient data merged, both prepubertal and adolescent patients … Future Research Individual Patient Data Meta-Analysis • We believe that an individual patient data

9170. Archived: Evidence Summary: Osteoporosis to Prevent Fractures: Screening | United States Preventive Services Taskforce
      www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary1/osteoporosis-screening-june-2018
      June 26, 2018 - statistical significance because of a small number of fractures and early termination of the study for safety … variables in common (eg, age, weight, hormone therapy use), there was considerable heterogeneity in the patient … interventions that might reduce the risk of osteoporotic fractures, such as functional assessment, safety … that rely on BMD measurement wholly or in part may not be the most accurate approaches for identifying patients … the key questions that the review will address to allow the USPSTF to evaluate the effectiveness and safety

9171. Interventions-Horizon-Scan-High-Impact-1306 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/interventions-horizon-scan-high-impact-1306.pdf
      June 01, 2013 - offering EDs designed to cater specifically to the special needs of the senior population to improve safety … unwilling to use it and technology-savvy patients. … 83 patients) at the UNM HCV clinic and 49.7% (73 of 147 patients) at ECHO sites (p=0.57). … Serious adverse events occurred in 13.7% of the patients at the UNM HCV clinic and in 6.9% of the patients … safety (structural changes), focusing care delivery (protocols), and improve follow-up (staff to assist

9172. Pediatric Medical Complexity Algorithm (pdf file)
      www.ahrq.gov/sites/default/files/wysiwyg/pqmp/measures/chronic/chipra-141-fullreport.pdf
      July 01, 2017 - , and society (unrelated to cost) • Fiscal burden of measure focus (e.g., clinical condition) on patients … Measure Topic – patient safety: No. k. Measure Topic – family experience with care: No. l. … priori to allow for stable estimates of PMCA’s sensitivity and specificity for correctly classifying patients

9173. Archived: Evidence Summary: Obesity in Adults: Screening and Counseling, 2003 | United States Preventive Services Taskforce
      www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obesity-in-adults-screening-and-counseling-2003
      December 15, 2003 - Pharmacotherapy appears safe in the short term; long-term safety is less established. … Safety concerns have eliminated several options. … Evaluation of the safety and efficacy of sibutramine, orlistat and metformin in the treatment of obesity … Efficacy and safety of sibutramine in obese white and African American patients with hypertension: a … Patient satisfaction and results of vertical banded gastroplasty and gastric bypass.

9174. Interventions to Prevent Falls in Older Adults: Updated Evidence Report and Systematic Review of the USPSTF (pdf file)
      www.uspreventiveservicestaskforce.org/home/getfilebytoken/nMb54adBfgajp8dG87kPcw
      April 17, 2018 - alone or in combination with or without intervention customization based on an initial comprehen- sive patient … the key questions that the review will address to allow the USPSTF to evaluate the effectiveness and safety … Seven trials recruited patients at average risk of falling, in which the only risk factor for falls was … High-Risk Definition Three trials recruited only patients at high risk (based on vary- ing definitions … The exercise interventions included in these multifactorial trials were similar to what patients receive

9175. Interventions in Primary Care to Promote Breastfeeding: An Evidence Review (pdf file)
      www.uspreventiveservicestaskforce.org/home/getfilebytoken/WYuzSoTB7frsav2gnsP7SR
      January 01, 2010 - Characteristics of Randomized, Controlled Trials Study, Year (Reference) Design Country Patients, n … United States 59 Low-income, minority Ed†††† Prenatal, peripartum Control education (baby care and safety … the effects of breastfeeding classes for expectant fathers to control group classes of baby care and safety … addition to proper randomization, the quality of the RCTs can be improved with clear and unbi- ased patient … Meta- analysis of continuous outcome data from individual patients. Stat Med. 2001; 20:2219-41.

9176. Effectiveness of Primary Care–Relevant Treatments for Obesity in Adults: A Systematic Evidence Review for the USPSTF (pdf file)
      www.uspreventiveservicestaskforce.org/home/getfilebytoken/hbSopN6uA9u-4EQuKtRGDP
      October 01, 2011 - whether the trial was conducted in primary care, setting (United States or not), quality, and selected patient … Safety profile of orlistat: results of a prescription-event monitoring study. … b) Are there differences in efficacy between patient subgroups (i.e., age 65 y or older, sex, race/ethnicity … c) Are there differences in efficacy between patient subgroups (i.e., age 65 y or older, sex, race/ethnicity … a) Are there differences in adverse effects between patient subgroups (i.e., age 65 y or older, sex,

9177. Tinnitus Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_executive.pdf
      August 01, 2013 - For adults with subjective idiopathic tinnitus, what prognostic factors, patient characteristics, and … for further evaluation or treatment Comparative e�ectiveness of treatment by prognostic factors, patient … For adults with subjective idiopathic tinnitus, what prognostic factors, patient characteristics, and … rTMS is limited, and also noted the lack of long-term monitoring within the studies with respect to safety … • Specify patient medical histories more clearly.

9178. Surveillance Report: CER 30: Comparative Effectiveness of Pain Management for Hip Fracture (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/hip-fracture-pain_surveillance.pdf
      July 08, 2015 - adults (≥50 years) admitted to the hospital following acute hip fracture, how do the effectiveness and safety … , as stated by the study investigators or evident from the study characteristics (e.g., mean/SD of patient … Versus Alendronate (VIVA) study: real-world adherence and persistence to medication, efficacy, and safety … Hip fracture management: tailoring care for the older patient. JAMA,307:20:2185-94. •! … Comparative safety of anesthetic type for hip fracture surgery in adults: retrospective cohort study

9179. Longitudinal Telephony & Multiple Disease Management System to Improve Ambulatory Care for Complex Patients - Final Report (pdf file)
      digital.ahrq.gov/sites/default/files/docs/publication/r18hs017855-friedman-final-report-2013.pdf
      January 01, 2013 - Patient-Subject Identification All patients admitted to two specified inpatient general medical services … to the patient. … Once the patient was enrolled, the next envelope was opened and the patient assigned to one of the two … In fact, he said that even though the patient population at BMC is “different,” still most patients … We could speculate that the existing safety net in Massachusetts has helped prevent the deleterious

9180. Appendix K Rapid Evidence Review Treatments for Clostridium difficile Colitis (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/clinical-pathway-methods-report-appendix-k.pdf
      February 01, 2018 - colon diversion, vancomycin therapy delivered via enema should be added to treatments above until the patient … to antibiotics and other treatments, use of FMT is adequately supported by the current evidence on safety … However, it may be helpful in patients with hypogammaglobulinemia. … This recommendation is based on very low- quality evidence but places a high value on patient preferences … Components Notes Costello 201619 Australia Includes flowchart for route of delivery of FMT, from patient