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  1. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Jz4WcZ2Wy3-nV6jNUrwUzX
    June 20, 2017 - and Drug Administration reviews for generics are focused on bioequivalence rather than efficacy and safety … the key questions that the reviewwill address to allow the USPSTF to evaluate the effectiveness and safety … Efficacy of Interventions by Patient Subgroups Key Question 4c. … Safety and efficacy of Xenical in children and adolescents with obesity-related diseases [NCT00001723 … controlled trial to evaluate a behavioral “stepped-down” weight loss intervention for adolescent patients
  2. www.uspreventiveservicestaskforce.org/home/getfilebytoken/abTWXPvJyAMcqN9KcEt-vt
    September 06, 2016 - the key questions that the review will address to allow the USPSTF to evaluate the effectiveness and safety … Most (71%) had a close contact with a patient with active TB within 2 years; 25% were included solely … Possible hypersensitivity was re- ported in 0.5% of patients receiving isoniazid and 4.1% of patients … Comparable specificity of 2 commercial tuberculin reagents in persons at low risk for tuberculous infection … Safety of an ofloxacin-based antitubercular regimen for the treatment of tuberculosis in patients with
  3. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/healthy-lifestyle-and-physical-activity-for-cvd-prevention-adults-without-known-risk-factors-behavioral-counseling
    July 26, 2022 - A randomized intervention of physical activity promotion and patient self-monitoring in primary health … Physical activity counseling in overweight and obese primary care patients: outcomes of the VA-STRIDE … Patient Educ Couns . 2011;85(1):122-126. doi:10.1093/her/cyr046 85. Jeffery RW, French SA. … Randomized controlled trial of physical activity counseling for older primary care patients.  … the key questions that the review will address to allow the USPSTF to evaluate the effectiveness and safety
  4. www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-children-and-adolescents-screening-june-2017
    June 20, 2017 - Clinicians should understand the evidence but individualize decision making to the specific patient or … Clinical Considerations Patient … Individual-patient meta-analysis could be beneficial in helping understand the differences between patients … Efficacy and safety trials of weight loss medications for pediatric populations with obesity are needed … Predicting weight loss and maintenance in overweight/obese pediatric patients.
  5. www.uspreventiveservicestaskforce.org/home/getfilebytoken/4TToeya43r5Qc5A6TjFGWS
    August 01, 2023 - :10.1001/jama.2023.9864 Editorial pages 417 and 419 Multimedia Related article page 454 and JAMA Patient … the key questions that the review will address to allow the USPSTF to evaluate the effectiveness and safety
  6. www.uspreventiveservicestaskforce.org/home/getfilebytoken/U4Vu9hcmHtD7snox6qbPja
    June 21, 2022 - 2347. doi:10.1001/jama.2021.15650 Editorial page 2294 Multimedia Related article page 2326 and JAMA Patient … the key questions that the review will address to allow the USPSTF to evaluate the effectiveness and safety … Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin: a randomized
  7. www.uspreventiveservicestaskforce.org/home/getfilebytoken/NZ_RQWxMMR8Vym-yJuqru-
    May 23, 2019 - Drug effects that vary by patient group make it more difficult to identify the effects of a single drug … One Antihypertensive Drug with Another* Study, Year (Reference) Quality Population Length of Study Patient … of 1000 patient-years in each group; prespecified outcomes 8 Pahor et al., 2000 (73) Good PatientsSafety of treatment, changes in risk factors, and incidence of coronary heart disease. … Expanded Clinical Evaluation of Lovastatin (EXCEL) study results: two-year efficacy and safety follow-up
  8. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/vitamin-supplementation-to-prevent-cvd-and-cancer-preventive-medication
    June 21, 2022 - Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin: a randomized … the key questions that the review will address to allow the USPSTF to evaluate the effectiveness and safety
  9. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/diabetes-mellitus-type-2-in-adults-screening-2003
    February 03, 2003 - Drug effects that vary by patient group make it more difficult to identify the effects of a single drug … Safety of treatment, changes in risk factors, and incidence of coronary heart disease. … Expanded Clinical Evaluation of Lovastatin (EXCEL) study results: two-year efficacy and safety follow-up … 0.002) 7.4% vs. 7.2% ( P > 0.2) 6.5% vs. 12.9% for all-cause mortality ( P = 0.034) NR One patient … of 1000 patient-years in each group; prespecified outcomes 8 RR vs. diuretics or β-blockers †
  10. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary23/diabetes-mellitus-type-2-in-adults-screening-2008
    June 15, 2008 - in treating type 2 diabetes and prediabetes 111-136 reveal some important new data related to the safety … Further work is also needed to examine the effect of screening and diagnosis on patient self-efficacy … Patient Educ Couns 2004;53:269-75. … Systematic review: comparative effectiveness and safety of oral medications for type 2 diabetes mellitus … Statin safety: a systematic review. Am J Cardiol 2006;97:52C-60C.
  11. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-dyslipidemia/statin-use-in-adults-preventive-medication
    November 13, 2016 - Studies enrolling older adults were also eligible if the results were reported separately for patients … Quality Rating We planned for 1 investigator to abstract details about each article's study design, patient … Although 4 trials of statins for primary prevention enrolled patients younger than 40 years, results … Two-year statin therapy does not alter the progression of intimamedia thickness in patients with type … Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056
  12. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-dyslipidemia/statin-use-in-adults-preventive-medication-november-2016
    November 13, 2016 - Studies enrolling older adults were also eligible if the results were reported separately for patients … Quality Rating We planned for 1 investigator to abstract details about each article's study design, patient … Although 4 trials of statins for primary prevention enrolled patients younger than 40 years, results … Two-year statin therapy does not alter the progression of intimamedia thickness in patients with type … Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056
  13. www.uspreventiveservicestaskforce.org/uspstf/recommendation/osteoporosis-screening
    January 14, 2025 - Clinicians should understand the evidence but individualize decision-making to the specific patient or … In the absence of evidence, clinicians and their patients should decide together whether to be screened … Racial disparities and inequalities in the management of patients with osteoporosis. … Racial disparities, FRAX, and the care of patients with osteoporosis. … Cardiovascular and skeletal safety of zoledronic acid in osteoporosis observational, matched cohort study
  14. www.uspreventiveservicestaskforce.org/home/getfilebytoken/XCAMvXugbjnYnGmeF5GtUS
    April 13, 2021 - 2 of the 3 studies Low for no benefit Both RCTs included men and women Findings not applicable to patients … Clinical and laboratory safety of one year’s use of a combination calcium + vitamin D tablet in ambulatory … Muscle strength and mobility in vitamin D–insufficient female geriatric patients: a randomized controlled … The necessity and safety of calcium and vitamin D in the elderly. … Effects of vitamin D supplementation on glycated haemoglobin and fasting glucose levels in hypertensive patients
  15. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/falls-prevention-community-dwelling-older-adults-interventions
    June 04, 2024 - multiple components such as medical history, medication review, clinical and laboratory tests, and patient … The exercise interventions included in the multifactorial trials are similar to what US patients receive … Patients with recurrent falls attending Accident & Emergency benefit from multifactorial intervention—a … The efficacy and safety of exercise for prevention of fall-related injuries in older people with different … the key questions that the review will address to allow the USPSTF to evaluate the effectiveness and safety
  16. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cancer/aspirin-to-prevent-cardiovascular-disease-and-cancer
    April 11, 2016 - For total cancer, we based our review on 2 individual-patient data (IPD) meta-analyses of randomized, … Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data … Efficacy and safety data. J Neurol Sci . 1997;151(Suppl):S1-77. [PMID: 9276859] 60. … A Study to Assess the Efficacy and Safety of Enteric-Coated Acetylsalicylic Acid in Patients at Moderate … We used data from the individual-patient data meta-analysis (if data were not reported in the study or
  17. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cancer/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
    April 11, 2016 - For total cancer, we based our review on 2 individual-patient data (IPD) meta-analyses of randomized, … Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data … Efficacy and safety data. J Neurol Sci . 1997;151(Suppl):S1-77. [PMID: 9276859] 60. … A Study to Assess the Efficacy and Safety of Enteric-Coated Acetylsalicylic Acid in Patients at Moderate … We used data from the individual-patient data meta-analysis (if data were not reported in the study or
  18. www.uspreventiveservicestaskforce.org/home/getfilebytoken/HhFR4LyVtxMcwmafRH6Ehp
    June 04, 2024 - Editorial Multimedia Related article and JAMA Patient Page Supplemental content CME at jamacmelookup.com … the key questions that the review will address to allow the USPSTF to evaluate the effectiveness and safety … multiple compo- nents such as medical history, medication review, clinical and labo- ratory tests, and patientPatients with recurrent falls attending Accident & Emergency benefit from multifactorial intervention–a … The efficacy and safety of exercise for prevention of fall-related injuries in older people with different
  19. www.uspreventiveservicestaskforce.org/home/getfilebytoken/8dzfZ_s3tZueoEh5Xzh-3A
    July 26, 2016 - the key questions that the review will address to allow the USPSTF to evaluate the effectiveness and safetyPatients were examined every 3-6 mo for 10 y. … All patients included had follow-up time of >3 mo and >10 y. … diagnostic accuracy were conducted in Australia, where knowledge of skin protection habits and sun safetyPatient-reported data on cosmetic harms is important.
  20. www.uspreventiveservicestaskforce.org/uspstf/recommendation/healthy-diet-promotion-behavioral-counseling-1996
    January 01, 1996 - Such interventions are not easily reproduced in the typical physician-patient clinical encounter. … , by emphasizing to the patient the health benefits of good nutrition, and by referring those requiring … Safety of treatment, changes in risk factors, and incidence of coronary heart disease. … Efficacy and safety of lowering dietary intake of fat and cholesterol in children with elevated low-density … Nutrition education for risk factor reduction and patient education: a review.

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