-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_surveillance.pdf
September 01, 2012 - Is the portion of the CER that is
probably or certainly out of date an issue of safety (a drug withdrawn … , blinding of the
diagnostic test reader to patient
history/other clinical
information, and use of … evaluated
only patients with non-palpable
breast masses,
63
and one study
evaluated only patients … Are there other factors and considerations (e.g., safety, care setting, patient preferences, ease of … Are there other factors and considerations (e.g., safety, care setting, patient preferences, ease of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
January 01, 2017 - goal of
improving patient care. … patients. … patients with multiple comorbidities. … Efficacy and safety
of individual second-generation vs. first generation antipsychotics
in first-episode … Efficacy and safety
of second-generation long-acting injections in schizophrenia:
a meta-analysis of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-treatment_surveillance.pdf
January 01, 2013 - KQ 2: Does treatment of open-angle glaucoma improve patient-reported outcomes? … It will still be
possible to compare the
effectiveness of different treatments
on patient-reported … Safety:
Both demonstrated comparable safety
and tolerability
Digiuni 201214
Double-blind RCT
184 … Safety: no major complications were
observed. … to 12 months postop
Efficacy:
SLT and ALT were equally effective
Safety:
15 patients excluded for
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-cancer-risk-reduction_research.pdf
October 25, 2010 - attention on the strength and limits of evidence from research studies about the effectiveness and
safety … Questionnaires of patients
Decision aids and decision modeling
Patient navigators
Observational … Patient - understanding why more patients
do not use SERMs
b. … A Phase I, open
label, oral, single-dose, escalating,
randomized, parallel study to evaluate
safety … Tamoxifen-associated
vasculitis in a breast cancer patient.
-
effectivehealthcare.ahrq.gov/sites/default/files/renal-cancer_disposition-comments.pdf
February 24, 2016 - If
the emphasis is on preventing harm, then conversion to open surgery
for the sake of safety from … may
influence patient perception of the treatment they
received. … Even a patient without CKD-Stage I or II, if young enough will
experience renal functional decline over … In the
case of the latter, such as a patient with limited life expectancy due to
coexisting medical … If we had a patient with a
2 cm enhancing real mass that we thought had a 60% pretest
probability,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout-management-disposition-160721.pdf
March 15, 2016 - If a patient
progresses to ‘chronic gout’, it simply indicates that the patient has been inadequately … Regarding the safety
outcomes, were only these specific outcomes selected? … self reports showed that of the 30 patients only 1
patient in weight reduction group reported making … see general comments, particularly with regard to inclusion of comparative
efficacy and comparative safety … Clinical efficacy
and safety of successful longterm urate lowering with febuxostat of Allopurinol in
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1512.pdf
December 01, 2015 - Investigators observed no new safety concerns for the implant. … Investigators observed no new safety concerns
beyond what is known for the GLP-1 receptor agonist class … , two patients underwent
operations for band or port complications, and one patient underwent band … The FAME Study consisted of 2 phase III pivotal trials
that assessed the product’s safety and efficacy … A study of the safety and efficacy of a
new treatment for diabetic macular edema.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_executive.pdf
June 01, 2013 - Do the comparative safety and
effectiveness of these therapies differ among specific
patient subgroups … Do the comparative safety and
effectiveness of these therapies differ among specific
patient subgroups … Do the comparative safety and
effectiveness of these therapies differ among specific
patient subgroups … Do the comparative safety
and effectiveness of these therapies differ among
specific patient subgroups … Do the comparative safety and effectiveness of these
therapies differ among specific patient subgroups
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_executive.pdf
January 01, 2010 - large proportion of variation is not
explained by some facilities having much higher or lower
risk patients … is
variation of the magnitude we see in use of cesarean after
taking into account differences in patient … characteristics,
the conclusion is that provider preferences, and to a
lesser extent patient preferences … In another study, injection of
hyaluronidase into the cervix in the outpatient clinic
for patients … Modifications
and safety evaluation would be a prerequisite to future
trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_disposition-comments.pdf
January 01, 2010 - Perhaps
this could be reworded as “provider preferences, and to a
lesser extent patient preferences … Perhaps this could be reworded as “provider
preferences, and to a lesser extent patient preferences… … However, when they suggest consideration of innovative
means of masking patients, they might have been … TEP #2 Discussion &
Conclusion
Summary for KQ1 should reiterate the issues around the
safety of the … There was
no attempt in this study to look at VBACs rated to outcomes,
safety or guideline evidence
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/major-depressive-disorder-disposition-160504.pdf
December 08, 2015 - During followup, patients
initially treated with psychotherapy
received no further treatment; patients … of psychotherapy because you blind the provider of a
psychological treatment and the patient is an … Since
these are non-psychotic patients I would think it is not so much a matter
of allowing patients … of the physician’s
supervision or monitoring (although the patient may elect to keep the
physician … here given
the implications for patient safety.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/atrial-fibrillation_research-protocol.pdf
May 22, 2012 - Do the comparative safety and
effectiveness of these therapies differ among specific patient subgroups … Do the
comparative safety and effectiveness of these therapies differ among specific patient
subgroups … Do the comparative safety
and effectiveness of these therapies differ among specific patient subgroups … Do the comparative safety and effectiveness of these therapies
differ among specific patient subgroups … Does the comparative
safety and effectiveness of these therapies differ among specific patient subgroups
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_disposition-comments.pdf
September 10, 2014 - Various stakeholders – including patients and
patient advocates, frontline clinicians, clinical
researchers … As stated in the preceding row of this table,
various stakeholders – including patients and
patient … work-up than patients with nonpalpable lesions. … , patients on aspirin,
Plavix, etc. … Will safety- net institutions take a bigger
economic hit than private offices?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_executive.pdf
January 01, 2014 - had extensive premarket evaluation and
study protocol evaluation; however, premarketing testing
for safety … Key Questions
Our objective was to systematically review the literature on
the effectiveness and safety … by other patients. … had major problems
that limited our ability to make firm conclusions about
the effectiveness and safety … Efficacy and safety of the
freeze-dried cultured human keratinocyte lysate, LyphoDerm 0.9%,
in the
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-e-2.xlsx
January 01, 2017 - 18% (9/50) vs. 10% (5/50)
RR 1.80 (95% CI 0.65 to 4.99) NR Placental abruption: none reported
(No patient … CR per se; Patient comparison groups from 2 diff hospitals/geographic locations; Excluded co-morbidities … Cundiff reports on 1179 patients, with a stated focus of “neonatal safety" and appears to only include … IP based on patient preference? Fewer OP vs. … , respectively. [7 patients in each group had forcep delivery.]
-
effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1412.pdf
December 01, 2014 - Experts were optimistic that reductions in PN use could potentially improve patient
health outcomes … Experts expected to see additional scrutiny of teduglutide’s safety and its
impact on cost of care … PN reduction might significantly
improve patient outcomes and quality of life. … Safety
and efficacy of teduglutide after 52 weeks of
treatment in patients with short bowel intestinal … Making 'every patient counts' a
business imperative. [internet].
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
March 01, 2012 - Process
In 1979, the FDA published its first Guidance Document
for the clinical evaluation of the safety … Patient inclusion criteria for FDA
clinical trials consisted of objective evidence of disease
(i.e. … (Cramer, 2008) Adherence (or
compliance) is defined as “the extent to which a patient acts in
accordance … In March 2010, the
FDA issued a followup to its 2007 safety review,
noting the inconsistency in the … And what patient factors are important
(such as the aforementioned low BMD at baseline)
in terms of
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/musculoskeletal-complaints-tests-children_research-protocol.pdf
September 29, 2010 - Rheumatology (ILAR)15 have developed classification criteria that are frequently used to classify
patients … search strategies designed to identify evidence relevant to questions of efficacy,
effectiveness and safety … As noted in the background section, patients with JIA can have symptoms of MSK pain and
joint swelling … Prevalence of autoantibodies to cyclic citrullinated
peptide in patients with rheumatic diseases other … A patient with undiagnosed
limb pain and/or joint swelling is considered to be a patient who presents