-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-13121.pdf
December 05, 2013 - A patient may choose to receive more than one injection over time. … its approval, without following good manufacturing practice,
and without proving the treatment’s safety … stating that MSC therapy is investigational
because of insufficient evidence or insufficient long-term safety … such as a hospital blood bank or blood processing laboratory)
according to standard blood-processing safety … Health care delivery infrastructure and patient management: Because patients with OA
already have the
-
effectivehealthcare.ahrq.gov/sites/default/files/08_functional_limitations_potential_high_impact_2012-12-10.pdf
January 01, 2012 - Use of the system would
represent a way to purportedly enhance patient mobility and allow patients … of dimethyl fumarate because of the efficacy and safety profile reported in patients with
RRMS. … Experts remained divided on per-patient costs with OBI-1 therapy, but thought clinicians and
patients … Regarding potential
acceptance by patients and clinicians, one clinical expert commented, “The safety … One research expert opined that elderly
patients may have more reservations than a younger patient
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-topic-refinement.pdf
November 01, 2022 - FDA)
makes decisions about the approval for marketing of products based on demonstrations
of their safety … Patient-
important outcomes may or may
not be patient-reported (e.g.,
death).
I. … For
studies that involve researching
the safety and effectiveness of
new drugs and biological
products … For studies that involve researching the safety and
effectiveness of new drugs and biological products … "patient access schemes"[All Fields]
8.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
August 01, 2013 - The number of patients included in studies ranged
from fewer than 100 to 170,291, with overlap in patient … The number of patients included in studies ranged
from fewer than 600 to 170,291, with overlap in patient … Warfarin
Ischemic stroke 1 (707) SOE = Low
9 LAA patients (1.3 events per 100 patient-years) and 6 … warfarin patients (1.6 events per 100 patient-years) had
ischemic stroke, demonstrating no difference … Given
variability in patient populations, concomitant therapies,
and underlying patient care, cross-trial
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/white-paper-roadmap-interventions.pdf
November 01, 2020 - The information in this report is intended to help healthcare decision makers—patients and
clinicians … information, i.e., in the context of available resources
and circumstances presented by individual patients … Direction of effect
Serious adverse events
Rate Ratio: 1.10 (95% CI,
0.70 to 1.71)
Low SOE
In patients … Pharmacologic and Nonpharmacologic Therapies
in Adult Patients With Exacerbation of COPD: A
Systematic … Comparative
effectiveness and safety of cognitive behavioral
therapy and pharmacotherapy for childhood
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/emt-naloxon_research-protocol.pdf
November 29, 2016 - the comparative benefit and harms of titration of naloxone
administered by EMS personnel until the patient … resumes sufficient spontaneous
respiratory effort versus until the patient regains consciousness? … arrest, function, quality of life,
other clinical sequelae of opioid overdose; healthcare utilization indicators … Review of naloxone safety for opioid overdose: practical
considerations for new technology and expanded … National Highway Traffic Safety Administration. The National EMS Scope of
Practice Model.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia_research.pdf
January 01, 2013 - A New Taxonomy for Stakeholder
Engagement in Patient-Centered Outcomes
Research. … • No study performed analyses by patient subgroups. … We
contacted the National Kidney Foundation Patient and Family Council to invite CKD
patient/patient … In addition to diagnostic accuracy and safety, stakeholder discussion of the
topic included additional … A new taxonomy for stakeholder
engagement in patient-centered outcomes
research.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research.pdf
March 01, 2013 - Efficacy and cardiac safety of
propiverine in elderly patients - a double-
blind, placebo-controlled … Efficacy and safety of tolterodine in patients
with detrusor instability: a dose-ranging
study. … Efficacy
and safety of solifenacin succinate in Korean
patients with overactive bladder: a
randomised … Efficacy and cardiac safety of
propiverine in elderly patients - a double-
blind, placebo-controlled … Efficacy and safety of tolterodine in patients
with detrusor instability: a dose-ranging
study.
-
effectivehealthcare.ahrq.gov/sites/default/files/tnd-0855-170515.pdf
April 28, 2017 - A recent study found that patient ratings of mobile
health applications are poor indications of those … and are
available on patients’ mobile devices. … A recent study found that patient ratings of mobile health applications are poor
indicators of those … Telehealth: Mapping the Evidence for Patient
Outcomes From Systematic Reviews. … Developing a Framework for Evaluating the
Patient Engagement, Quality, and Safety of Mobile Health Applications
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0855-170515.pdf
April 28, 2017 - A recent study found that patient ratings of mobile
health applications are poor indications of those … and are
available on patients’ mobile devices. … A recent study found that patient ratings of mobile health applications are poor
indicators of those … Telehealth: Mapping the Evidence for Patient
Outcomes From Systematic Reviews. … Developing a Framework for Evaluating the
Patient Engagement, Quality, and Safety of Mobile Health Applications
-
effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-37-opiod-use-adults-comments.pdf
November 03, 2020 - , an educational pamphlet for patients,
provision of patient information and pain
management training … This alarm
system can create a true safety net for elderly
patients, with will decrease anxiety and … General
Comments
Research Is Needed to Increase Safety and
Provide Effective Pain Management in Older … COPD)
o cardiac disease
o neurological disease
We agree that more research is needed to
increase safety … Masimo stands ready to work
with you as you address these important patient
safety issues for older
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/outcomes-testing-evaluation_research.pdf
January 01, 2009 - Additional patient
outcomes and pathways in evaluations of testing. … No differences in health indicators were found at 1 year among patients who
self-monitored compared … One of the most obvious pathways between testing and patients’ health runs
through patient adherence … Prenatal screening and diagnosis of
congenital toxoplasmosis: a review of
safety issues and psychological … Full range of effects of testing on patient outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/whitepaper4-bossuyt02262010-2.pdf
January 01, 2009 - Additional patient
outcomes and pathways in evaluations of testing. … No differences in health indicators were found at 1 year among patients who
self-monitored compared … One of the most obvious pathways between testing and patients’ health runs
through patient adherence … Prenatal screening and diagnosis of
congenital toxoplasmosis: a review of
safety issues and psychological … Full range of effects of testing on patient outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-gain-prevention_executive.pdf
January 01, 2020 - inclusive enrollment criteria.19,20
Scope and Key Questions
We aimed to compare the effectiveness, safety … For the intermediate outcomes,
safety, clinical, and quality of life outcomes, we only
abstracted data … Studies of overweight and obese patients were included if the study did not describe the goal of the … Health Indicators Warehouse. … Healthy Weight in Adults. www.
healthindicators.gov/Indicators/ Healthyweightinadults_1207/
Profile/Data
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-dystocia_research-protocol.pdf
July 28, 2016 - balance between harms and benefits for both mother and baby that is
considered acceptable to most patients … We will link studies to avoid duplication of patient cohorts. … The safety outcomes will be framed to help identify adverse events, including
those from drug therapies … methodological quality of individual studies, study type, the
characteristics of the comparator, and patients … Key Informants
Key Informants are the end users of research, including patients and caregivers,
practicing
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
April 01, 2012 - Finally,
very little is known about the benefits or risks of these
drugs in different patient subgroups … KQ 2: For patients with PsA, do drug therapies differ
in their ability to improve patient-reported symptoms … KQ 3: For patients with PsA, do drug therapies differ in
harms, tolerability, patient adherence, or … eligibility (inclusion and exclusion) criteria were
designed with respect to study design or duration, patient … Safety and efficacy
of adalimumab in treatment of patients with psoriatic arthritis who
had failed
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
February 15, 2017 - an acute ACS event
• Settings:
o Primary, specialty, inpatient
KQ 2: What are the comparative safety … The safety outcomes will be framed to help identify adverse events, including those
from drug therapies … Cardiology Patient Page. … Aripiprazole5 Yes, as an
adjunct with an
antidepressant
FDA safety alert: uncontrollable urges to … care"[mesh] OR "Delivery of Health Care, Integrated"[Mesh] OR
"Patient Care Team"[Mesh] OR "Patient
-
effectivehealthcare.ahrq.gov/sites/default/files/01_-arthritis_potential_high_impact_june_2012.pdf
January 01, 2012 - These safety concerns may present barriers to
approval or barriers to diffusion if approved. … determinations stated MSC therapy is investigational because of insufficient evidence or long-term
safety … Both groups had similar safety
profiles.
29
In a study of patients with knee OA (Outerbridge grades … as a hospital
blood bank or blood processing laboratory) according to standard blood processing safety … These safety concerns may
present significant barriers to approval and diffusion if approved.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-disposition-comments-inhaled-corticosteroids.pdf
March 19, 2018 - What if they
didn’t result in patient receiving systemic
corticosteroids? … The combination of
BUD/Form is not approved for children under 12
but efficacy and safety studies discussed … Ensure homogeneity of patient populations
included in meta-analyses. … However, there is
heterogeneity in the patient populations enrolled
in these trials, in relation to … Tonya
Winders,
Asthma &
Allergy Network
We are not sure of this report's potential impact
in patient
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
September 01, 2014 - on test performance and safety is not clear. … provide additional information allowing the exploration of
heterogeneity for test performance and safety … Of note, studies often do not provide information on the
risk of cancer among included patients. … patients were biopsied with vacuum-assistance and others
were not) but the study did not report the … selection criteria, patient or lesion characteristics,
adverse events, or patient-relevant outcomes