-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_disposition-comments.pdf
December 30, 2015 - We included patient-centered
outcomes which are not exclusive to patient-reported
outcomes. … Providers use history and patient report to
diagnose insomnia disorder and assess patient
opinion regarding … Snavely Kenneth Liu Christopher Lines Thomas
Roth and David Michelson
Safety and efficacy of suvorexant … Both enroll healthy patients. … Patient-centered outcomes include outcomes that are
noticeable to patients and do not include only patient
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_technical-brief.pdf
January 01, 2020 - Some platforms have safety features, such as a handrail for balance. … Patient Populations
The patient populations included in studies of whole-body vibration therapy for … A number of safety issues for consumers, including safety features available on the devices
and the … When should patient outcomes be measured (length of followup)? … Questions for clinicians, patients, and patient advocates.
a.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer78_procalcitonin_disposition_20121210.pdf
October 05, 2012 - This
also applies to studies of other patient populations. … Commentator
& Affiliation Section Comment Response
PR #1 General
Concerns
Our second main concern is safety … worse for certain
infections).We suggest concluding that although PCT
guidance appears safe, true safety … – I wonder if
this might add value and, of course, would lead to less
confident assessments about safety … To me,
the benefits seem pretty modest (even if real) and the
safety uncertain, even before taking
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypothyroidism-hyperthyroidism-screening-treatment_research-protocol.pdf
March 11, 2010 - over 35 years of
age every 5 years (more frequently if the patient is at increased risk), but has not … (safe OR safety OR side-effect$ OR undesirable effect$ OR treatment
emergent OR tolerability OR toxicity … (effect$ OR reaction$ OR event$ OR outcome$) [tiab]
10. 8 AND 9
11. 10 OR 7 OR 6
P Patient issues … False Positive Reactions [Mesh]
7. patient preference* [tiab]
8. consequence* [tiab]
9. cost [tiab … Committee on Patient S, Quality I, Committee on Professional L.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/glaucoma-screening_research-protocol.pdf
November 16, 2010 - First, glaucoma is an asymptomatic disease that
patients do not notice until their disease is advanced … New evidence regarding the safety and efficacy of screening for chronic open–angle glaucoma has
emerged … Objectives
The objective of this review is to summarize the evidence regarding the safety and efficacy … : November 16, 2010
for screening for glaucoma will consider and compare, where possible, whether patients … Patient satisfaction (Secondary outcome).
3.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_disposition-comments.pdf
May 20, 2013 - When the
capsule fails to pass and patients have symptoms, then a
patient may need x-rays to detect … When the capsule fails to pass and
patients have symptoms, then a patient may need x-rays
to detect … Public Comment:
SmartPill Corp
Executive Summary Safety profile and addressing comment that there … When the capsule fails to
pass and patients have symptoms, then a patient may
need x-rays to detect … When the capsule fails to pass and
patients have symptoms, then a patient may need x-rays
to detect
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive.pdf
October 01, 2006 - This report summarizes the evidence evaluating the
effect and safety of angioplasty with stent placements … What are the patient characteristics, including
etiology, predominant clinical presentation,
and severity … A
variety of indicators of the severity of ARAS and of
health problems, such as poorer kidney function … The
reviewed studies did not report any indicators that may
predict improved outcomes. … The other trial included patients with lower
grade stenosis (>50 percent) but did not exclude
patients
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotic-medicine-mortality-elderly_research.pdf
March 01, 2009 - about the outcomes, clinical effectiveness, safety, and appropriateness of health care items and … Potential Confounders
The patient characteristics were identified during the 6 months prior to each … The excess risk for non-cancer mortality was 25.7 per
1,000 patient-years (95% CI : 17.4 – 37.0). … The
efficacy, safety, and tolerability of
antipsychotics in the elderly. … The older patient: the ongoing
challenge of efficacy and tolerability.
-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1412.pdf
October 01, 2015 - According to the Cystic Fibrosis Foundation’s patient registry, almost 47% of CF
patients in the United … Data revealed patient survival on day 30 in patients treated with OCS (n=59) or
cold storage (n=77) … Patient survival at 6 months for patients with
OCS-treated lungs (n=36) and cold storage treated lungs … Efficacy and
safety of pirfenidone for idiopathic pulmonary
fibrosis. … Efficacy
and safety of nintedanib in idiopathic pulmonary
fibrosis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_surveillance.pdf
April 01, 2012 - Is the portion of the CER that is
probably or certainly out of date an issue of safety (a drug withdrawn … A patient experienced failure
of a new air supply hose and
woke up gasping for air; a
patient reported … In OSA patients prescribed nonsurgical treatments, what are the associations of pretreatment patient-level … Prospective trial of efficacy and safety of
ondansetron and fluoxetine in patients with
obstructive … Do Not Know
patient education), cognitive behavioral
therapy (given to patients and their
partners
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
February 01, 2013 - However, the overall strength
of evidence evaluation was based on patient-centered
clinical outcomes … Patient-Centered Outcomes
Short-term (≤ 30 days after the procedure), patient-
centered outcomes in … Of 83 patients in the FFR
group, 28 received stents (34%), while 86 of 94 patients
in the IVUS group … Both studies used IVUS in patients during PCI or
immediately after PCI, and compared them with patients … trials; and
third, hybrid and novel techniques need to be evaluated for
comparative efficacy and safety
-
effectivehealthcare.ahrq.gov/sites/default/files/adhd_executive.pdf
October 01, 2011 - Global
ratings of impairment also indicate continued benefit
throughout the extension studies for patients … Placebocontrolled
discontinuation trials, where patients receiving
treatment are allocated to continue … community, dependent on provider type and availability, provider
remuneration, and insurance status of patient … Safety and
tolerability of methylphenidate in preschool children
with ADHD. … Relapse prevention in pediatric patients with ADHD
treated with atomoxetine: a randomized, doubleblind
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hemorrhage-postpartum_disposition-comments.pdf
April 28, 2015 - Commentator &
Affiliation
Section Comment Response
In a normal pregnant patient … definitions that are clinically not significant and then
compare different treatments in managing a patient … Public Reviewer
#3
Mark Turrentine,
MD
General There will soon be published a national patient … safety
bundle on obstetrical hemorrhage (National Partnership
for Maternal Safety: Consensus Bundle … that was brought to this issue with the relatively recent
Potential Signals of Serious Risks/New Safety
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
February 01, 2013 - group; whether nonvertebral fractures were split out into fractures of the hip or wrist; or whether
patient … Patients in residential treatment
programs may be patients with more
severe symptoms or other
comorbidities … Outcomes
Regardless of the topic, SRs should focus on assessing a range of patient-centered outcomes … should identify the expected time
period of study that would be needed to identify effectiveness on patient-important … screened/eligible/enrolled/lost to withdrawn/follow-
up/analyzed, and effectiveness/efficacy and safety
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cerebral-palsy-feeding_research-protocol.pdf
June 12, 2012 - Some patients with oropharyngeal dysphagia and GER, particularly
those with severe CP, are also at risk … Indeed, chronic pulmonary disease related to aspiration is
the leading cause of death among patients … difficulties, reflecting the range in specific problems associated with feeding and nutrition in
patients … those that address
nutrition and growth.31 Despite a range of potential feeding interventions for patients … with CP,
synthesis is lacking on the efficacy, safety, and applicability of these interventions.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb_surveillance.pdf
July 06, 2015 - patient data from the BEAUTIFUL
and SHIFT trials. … Safety and efficacy of low blood pressures among patients with diabetes: subgroup analyses from the … /Surveillance/AdverseDrugEffects/ucm085916.htm
β http://www.fda.gov/Safety/MedWatch/SafetyInformation … We assessed the efficacy and safety of LCZ696, a first-in-class angiotensin receptor neprilysin inhibitor … (ARNI), in patients with this
D"13$
$
http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
August 01, 2012 - CER #40:
Effectiveness and Safety of Antiepileptic Medications
in Patients with Epilepsy
Original … of the report, patients are being asked to
fail first on carbamazepine regardless of patient history … However, our
data do not allow us to determine if an individual
patient or subset of patients would … Effectiveness and Safety of Antiepileptic
Medications in Patients with Epilepsy. … Efficacy and safety of innovator versus
generic drugs in patients with epilepsy: a
systematic review
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
August 01, 2012 - CER #40:
Effectiveness and Safety of Antiepileptic Medications
in Patients with Epilepsy
Original … of the report, patients are being asked to
fail first on carbamazepine regardless of patient history … However, our
data do not allow us to determine if an individual
patient or subset of patients would … Effectiveness and Safety of Antiepileptic
Medications in Patients with Epilepsy. … Efficacy and safety of innovator versus
generic drugs in patients with epilepsy: a
systematic review
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-web-interactive-presentation.pdf
September 01, 2019 - Associate Chief Medical Officer for Patient Safety and Clinical Quality
Assistant Professor of Medicine … with urinary incontinence, as
well as health system decisions related to improving patient safety and … We engaged the Associate Chief Medical Officer (CMO)
for Patient Safety and Clinical Quality and the … The Associate Chief CMO for Patient Safety and Clinical Quality is tasked with setting
Duke’s quality … agenda and coordinating patient safety and clinical quality activities across the
Duke Health System
-
effectivehealthcare.ahrq.gov/sites/default/files/functional-limitations-horizon-scan-high-impact-1306.pdf
June 01, 2013 - Using the
system would represent a way to purportedly enhance patient mobility and allow patients to … fumarate because of the efficacy and safety profile reported in patients with RRMS, the
experts thought … Regarding acceptance by both patients and clinicians, one clinical expert commented, “The safety
profile … Experts generally agreed that potential patient adoption would be high because of patients’ desire to … One research expert opined that elderly patients may have more reservations than a younger patient