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effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth-disposition-121205.pdf
September 07, 2012 - The safety signal
uncovered by the FDA was an excess of fetal death in patients
exposed to 17P. … , of note each of these is mediated
by the care provider as part of the process of
care; none are patient … A it must work for
patient B" clearly does not apply for 17OH. … Given that this document could be
used to provide guidelines for patient care and change
reimbursement … Physicians need to inform patients that there is a potential safety
signal with the administration of
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effectivehealthcare.ahrq.gov/sites/default/files/devdelays_adhd_autism_hi_impact.pdf
January 01, 2012 - for the patient and caregiver. … caregiver, researcher, or clinician who is monitoring the
readouts of those signals on a computer about indicators … safety.”
15
Several other experts were not as convinced about the intervention’s mechanism of
action … The expert indicated the intervention may pose safety issues in patients
with otitis media and asthma … Safety concerns, the closed environment of the HBOT chamber
(which could cause claustrophobia), and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-centered-medical-home_executive.pdf
July 01, 2012 - the variety of health care needs
of patients and to improve patient and staff
experiences, outcomes … A systems-based approach to improving quality
and safety
3. … Coordination of care (as perceived by patients)
c. Patient-provider interaction
2. … Effects on quality indicators for
chronic illness care and on clinical outcomes are uncertain. … safety risks (e.g., patients using email
for emergent medical issues), are possible and should be
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
September 01, 2012 - associated
with preterm birth represent untold
distress for families, as well as significant
costs to patients … However, these groups also note interest
in assessing long-term safety because the
Effective
Health … How do the effectiveness, adverse effects, and safety
of progestogen treatment differ based on the maternal … How do the effectiveness, acceptability, adherence,
adverse effects, and safety of progestogen treatment … One survey
addressed patient demand; 63 percent reported that patients
“never request”; 35 percent,
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effectivehealthcare.ahrq.gov/sites/default/files/toc.pdf
January 01, 2007 - The Comparative Effectiveness and Safety Emerging Methods
Symposium: A Tribue to Harry A. … Methodologic Challenges to Studying Patient Safety and Comparative
Effectiveness. … Assessment of Adherence to and
Persistence on Disease-Modifying Anti-Rheumatic Drugs (DMARDs) in Patients … Developing Indicators of Inpatient Adverse Drug
Events Through Non-Linear Analysis Using Administrative … Real-Time Vaccine Safety Surveillance for the
Early Detection of Adverse Events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccine-safety_disposition-comments.pdf
January 01, 2020 - statistical
significance, unless they can state with certainty that
the vaccine alone truly protects the patient … In addition, nothing is known
about the patient factors which may influence the effect
of the vaccine … 1 Research
Gaps—Page
129 line 43
Please change to: “Large scale studies may help to
determine patient … other AEs reported
(regardless of whether they were pre-specified
or mentioned spontaneously by the patient … Patients
received either a single dose of Zostavax or placebo.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
December 01, 2011 - If a patient has responded to one agent in the past,
is that agent better than current alternatives at … For adults with a depressive syndrome, do
commonly used antidepressants differ in safety,
adverse events … No evidence addressed how second-generation
antidepressants compare when a patient responds to one
agent … Furthermore, studies need to explore patient
preferences about dosing regimens and the level of
acceptance … Finally, no evidence addressed how second-generation
antidepressants compare when a patient responds
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-205-predictors-trauma-care-evidence-summary.pdf
April 01, 2018 - and
Quality in conjunction with the sponsoring partner
agency, the National Highway Transportation Safety … If the indicators of high-risk patients were
consistent, cleaner comparisons could be made both across … Washington, DC:
National Highway Traffic Safety Administration; February 2013. … Prehospital triage in
the injured pediatric patient. … Decision tool for the
early diagnosis of trauma patient hypovolemia.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/type-2-diabetes-medications-update_research-protocol.pdf
April 06, 2010 - Timing
We will include studies if patients have been on the medications for at least 3 months. … control with sulphonylureas or insulin compared with conventional
treatment and risk of complications in patients … Pioglitazone and risk of cardiovascular events in
patients with type 2 diabetes mellitus: A meta-analysis … Inclusion and exclusion criteria
Population and condition
of interest
□ All studies included patients … We excluded
studies that evaluated only patients with type I diabetes, impaired glucose tolerance, metabolic
-
effectivehealthcare.ahrq.gov/sites/default/files/s5.pdf
October 01, 2007 - Lohr, PhD
Background: Interest in new methods for comparative effective-
ness, drug and patient safety … Key Words: comparative effectiveness, drug safety, health care,
methods, patient safety, pharmaceuticals … For decades, researchers have used Medicaid data for
research on the initiation, continuation, and patient … Methodologic challenges to studying patient safety and
comparative effectiveness. … Developing indicators of
inpatient adverse drug events through nonlinear analysis using admin-
istrative
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rfviia.pptx
May 01, 2010 - The talk will cover the current evidence on the effectiveness and safety of using recombinant activated … Safety and efficacy of recombinant activated factor VII: a randomized placebo-controlled trial in the … Efficacy and safety of repeated perioperative doses of recombinant factor VIIa in liver transplantation … Safety and efficacy of a single bolus administration of recombinant factor VIIa in liver transplantation … Safety is defined via thromboembolic events and mortality, but individual studies often lack the statistical
-
effectivehealthcare.ahrq.gov/sites/default/files/rfviia.pptx
May 01, 2010 - The talk will cover the current evidence on the effectiveness and safety of using recombinant activated … Safety and efficacy of recombinant activated factor VII: a randomized placebo-controlled trial in the … Efficacy and safety of repeated perioperative doses of recombinant factor VIIa in liver transplantation … Safety and efficacy of a single bolus administration of recombinant factor VIIa in liver transplantation … Safety is defined via thromboembolic events and mortality, but individual studies often lack the statistical
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy_research-protocol.pdf
September 14, 2016 - While the
severity of disease varies between patients and over time in the same patient, asthma can … there is clear evidence of a relationship
between symptoms and exposure to an allergen to which the patient … use of medications.32 However, many studies may not define clearly the
population or characterize indicators … The activity domain contains 5 ‘patient-specific’ questions. … c) Serious adverse events (SAE): The event is serious and should be reported when the patient
outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-deprescribing.pdf
February 01, 2024 - What patient safety measures or indicators have been used to examine the
harm associated with polypharmacy … We answered Review Questions 1 and 2 by focusing on the harms and patient
safety measures or indicators … safety measures, AHRQ’s
Patient Safety Indicators, or the National Committee for Quality Assurance … patient
safety–related measures. … What Patient Safety Measures or
Indicators Have Been Used To Examine the Harm
Associated With Polypharmacy
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-assessment-research-updates_research.pdf
September 15, 2008 - In doing so, CERs more closely parallel the decisions facing clinicians, patients and
policymakers, … • Has there been a change in scope (e.g., new patient populations, new outcomes)? … Comparative Effectiveness of Epoetin and Darbepoetin for Managing Anemia in
Patients Undergoing Cancer … of medical, surgical, and
endoscopic treatments for improving objective and subjective outcomes in patients … Yes/No Yes/No Yes/No
7
10 percent to 65 percent of surgical
patients still require medications
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1406.pdf
June 01, 2014 - Preliminary data for these interventions
are promising, and ongoing trials are clarifying the safety … Results and Discussion of Comments
Seven experts, with clinical, research, patient safety, and health … widespread, if data support its efficacy and safety, the experts thought. … Investigators reported high
patient adherence (81% and 94%; adherence defined as patients completing … that SPARX could positively affect patient health outcomes
by providing an alternative for patients
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-high-risk-drugs-rapid-response.pdf
January 01, 2024 - What patient safety measures or indicators have been used to examine the harm
associated with anticoagulant … safety measures or indicators. … Contextual information
• Rationale for PSPs
• Patient safety measures or indicators
• Toolkits and … What Patient Safety Measures or
Indicators Have Been Used To Examine the Harm
Associated With Anticoagulant … Director, General Patient Safety Program
Center for Quality Improvement and Patient Safety
Agency for
-
effectivehealthcare.ahrq.gov/sites/default/files/comparator-selection-in-observational-chapter-5.pptx
January 01, 2013 - with the underlying disease and its severity, general health status or frailty, quality of life, and patient … factor for adverse metabolic outcomes, but the magnitude of the confounding depends on the metabolic safety … Multiple data sources can be linked to enhance the validity of observational comparative effectiveness and safety … A direct relationship between the level of physician experience and better patient outcomes has been … A relationship between larger hospital volume and favorable patient outcomes is also well documented.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/unpublished-drug-trials-white-paper.pdf
December 01, 2024 - The information in this report is intended to help healthcare decision makers—patients and
clinicians … information, i.e., in the context of available resources
and circumstances presented by individual patients … Most AHRQ documents are publicly
available to use for noncommercial purposes (research, clinical or patient … Efficacy and safety of paroxetine treatment
for chronic PTSD: a fixed-dose, placebo-
controlled study … Efficacy
and safety of mifepristone in the treatment
of male US veterans with posttraumatic
stress
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_research-protocol.pdf
March 13, 2012 - The FDA
addresses the safety and effectiveness of diagnostic tests and the quality of the design
and … Historically, the FDA has subjected test kits to premarket
review of safety and effectiveness but not … Clinical utility should reflect patient outcomes such as
improved survival. … result from both preanalytic factors [e.g., sample
preparation] as well as analytic factors [such as reagents … Patient advocacy Web sites for colon cancer will be searched.