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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ahrq-healthcare-horizon-scan-protocol-operations-manual-151001.pdf
September 01, 2015 - Anticipated Cost Per Patient (if known)
11. … Potential Patient and Clinical Staff Safety Issues
14. … Patient Safety Issues (if applicable)
11. Required Resources
12. … as
• Additional, stronger, confirmatory data that could change perspectives on potential impact
• Safety … safety alert been issued that could signal a safety/efficacy change in perspectives
2.
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effectivehealthcare.ahrq.gov/sites/default/files/ahrq-healthcare-horizon-scan-protocol-operations-manual-151001.pdf
September 01, 2015 - Anticipated Cost Per Patient (if known)
11. … Potential Patient and Clinical Staff Safety Issues
14. … Patient Safety Issues (if applicable)
11. Required Resources
12. … as
• Additional, stronger, confirmatory data that could change perspectives on potential impact
• Safety … safety alert been issued that could signal a safety/efficacy change in perspectives
2.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-test_executive.pdf
April 01, 2013 - analyses to matched
studies that provide data on PCA3 and at least one other
comparator in the same patient … Utility of PCA3 in
patients undergoing repeat biopsy for prostate cancer. … Summary of Safety and
Effectiveness Data: PROGENSA PCA3 Assay, 2012. … cancer gene
3 urine assay cutoff in diagnosis of prostate cancer: a validation
study on an Italian patient … PCA3 as a diagnostic
marker for prostate cancer: a validation study on a Swedish patient
population
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_appendixes.pdf
January 01, 2009 - Use of lung transplantation survival
models to refine patient selection in cystic fibrosis. … growth hormone deficient hypopituitary adults: Demographic
and clinical characteristics, dosing and safety … The safety and effectiveness of human growth hormone
using pharmacological dosing. … D-3
Health Related Quality of Life (HRQoL): Assessment of the overall well-being of a patient. … with CF born before 1993 with at
least 4 annual lung function
measurements in the patient database
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1506.pdf
June 01, 2015 - Investigators observed no new safety concerns for the
implant. … Investigators observed no new
safety concerns beyond what is known for the GLP-1 receptor agonist class … Summary of safety and
effectiveness data (SSED) for MiniMed 530G
system. P120010. … Summary of safety and effectiveness data
(SSED). MiniMed 530G system. P120010. … A study of the safety and efficacy of a
new treatment for diabetic macular edema.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rotator-cuff-tears-future_research.pdf
February 01, 2013 - a sufficient number and variety of patients, such as patient
demographics and tear characteristics, … effects in patient subgroups. … 9/16/2009
Ongoing Studies that May Address
Knowledge Gaps
www.clinicaltrials.gov
NCT01122498: safety … What patient factors matter? … patient and chronic tears
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_disposition-comments.pdf
February 26, 2013 - ) with Figures 3
and 4 which for patient level data are shown for 6 RCT’s and 6
non-randomized studies … This is consistent with
patients included in the various FFR trials – all patients were
assessed by … Improved
patient-centered outcomes from FFR have been demonstrated
in a wide variety of patient subsets … of all cause death, documented MI, unplanned
hospitalization leading to urgent revascularization), safety … Enrollment in FAME II
was recently halted early by the DSMB (data safety and
monitoring board) due
-
effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1406.pdf
June 01, 2014 - Although propofol may be preferred for these
reasons, its use is complicated by safety concerns. … of the controversy among
clinical specialties (gastroenterology versus anesthesiology) about its safety … Patient
acceptance of the technology might be low, although one expert thought that elderly patients … Clinicians can access objective, accurate,
and timely data about patient adherence, to monitor patients … It may be
solely age-based (i.e., patients 65 years and older) or also based on patient complaint and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine_protocol-appendix_20111103.pdf
November 03, 2011 - exp patient care team/
3. exp delivery of health care, integrated/
4. integrated care.mp.
5. … exp Patient Education as Topic/
8. exp Health Education/
9. … surveillance.mp.
10. exp drug monitoring/
11. 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 or 9 or 10
12. exp patient … continued)
Source: www.effectivehealthcare.ahrq.gov
Published Online: November 3, 2011
A-8
13. exp patient … satisfaction/
14. exp patient care management/
15. 12 or 13 or 14
16. exp migraine disorders/dt
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effectivehealthcare.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-disposition-comments.pdf
June 09, 2021 - With
respect to subgroup analyses of
studies, patient level data was not
available. … cohort study included breast
cancer patient only. … accurate about including
cohort studies (I was confused whether cohort
studies were only considered for safety … outcomes
or both safety and efficacy outcomes). … Patient-level data was not
available.
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_disposition-comments.pdf
January 01, 2015 - We removed the word safety from
the title for Table D. … We
have discussed patient preference as well as
cost briefly as potential drivers. … Efficacy and
safety of the once-weekly GLP-1 receptor agonist
albiglutide versus sitagliptin in patients … varies with patient
characteristics. … 16 patients 0.2 in the placebo group P 0.42
definite acute pancreatitis in 17 patients 0.2 and 9
patients
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_disposition-comments.pdf
April 25, 2013 - It may or may not be of
interest, but there are recent studies showing safety of contrast-
enhanced … Safety of echocardiographic contrast in hospitalized
patients with pulmonary hypertension: a multi-center … We did not identify
any studies in PH looking at the perflutren lipid
microsphere for either safety … the effect of Definity on improving
the diagnostic accuracy of echo, hence, isolated data on
its safety … The question aims to determine the efficacy and safety
of echocardiography and biomarkers in “screening
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_disposition-comments.pdf
May 08, 2013 - (younger,
spinal cord patient and older, frail
nursing home or hospitalized
patients). … However, I think that
the outcome measures other than
complete wound healing that were
used as indicators … appropriately and
explicitly stated: To summarize the
available evidence comparing the
effectiveness and safety … We did not find studies on patient position/off-
loading. … While the reviewed studies
did not indicate harms with NPWT,
the FDA has issued warnings about
the safety
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-update_disposition-comments.pdf
August 16, 2016 - Examples might be the
demonstrated safety of ACEis/ARBs in ARAS, and
consistently similar long-term … Safety and efficacy of renal artery stenting
following suboptimal renal angioplasty for de
novo and … not the patient who
gets randomized. … Clearly future
clinical trials are needed in this patient population. … TEP Reviewer
#4
Miscellaneous Specific comment: p.12: “patient factors” 1 RCT found
that patients
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effectivehealthcare.ahrq.gov/system/files/docs/headaches-pregnancy-topic-brief.pdf
January 01, 2019 - Evaluation and management of headaches in pregnancy
A-2
Background
When a pregnant patient … None of these reported on
effectiveness, all outcomes were maternal and fetal safety and harms. … Imaging of Neurologic Conditions in Pregnant Patients. … Triptan safety during pregnancy: a
Norwegian population registry study. … Safety of diclofenac use during early
pregnancy: A prospective observational cohort study.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_executive.pdf
April 01, 2012 - between the drugs in younger patients. … Research based on
patient-centered outcomes provides patients and clinicians
the necessary information … safety was rarely available in RCTs, despite high
discontinuation rates suggesting that there were … • Evidence is insufficient for the long-term safety of
pharmacological treatments. … Self reported receipt of care
consistent with 32 quality indicators: national population survey of
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-centered-medical-home_research-protocol.pdf
February 23, 2012 - as a way of improving patient experiences,
outcomes, safety, and system efficiency.10-12 It is based … Intermediate patient outcomes (e.g., change in HbA1c for diabetic patients).
b. … A systems-based approach to quality, safety, and delivery of evidence-based care. … Intermediate patient outcomes (e.g., change in HbA1c for diabetic
patients).
ii. … care, superb access to care, and a systems-
based approach to quality and safety.
-
effectivehealthcare.ahrq.gov/sites/default/files/01_arthritis_potential_high_impact_2012-12-10.pdf
January 01, 2012 - The
investigators reported that patients treated with MSC therapy had improvements in patient pain … stated MSC therapy is
investigational because of insufficient evidence or insufficient long-term safety … Both groups had
similar safety profiles.
29
In a study of patients with knee OA (Outerbridge grades … Because PRP is theorized to be more effective in younger patients, the
treatment could alter patient … These safety concerns could present significant barriers to diffusion.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_surveillance.pdf
October 01, 2012 - Is the portion of the CER that is
probably or certainly out of date an issue of safety (a drug withdrawn … that
adds to this a comparison
of monitoring urinary
albumin and urinary total
protein to predict patient … Comparison of urinary albumin and
urinary total protein as predictors of patient
outcomes in CKD. … The primary composite end point
occurred in 26 patients in the sulodexide group
and 30 patients in … Retrospective
longitudinal cohort
study of urinary
albumin and
urinary total
protein to predict
patient
-
effectivehealthcare.ahrq.gov/sites/default/files/11_peptic_ulcer_potential_high_impact_2012-12-111.pdf
January 01, 2012 - POEM is performed with the patient under general anesthesia. … Additional scrutiny of teduglutide’s safety and its
impact on cost of care is likely going forward … TSO’s impact is perceived to be dependent on
further demonstration of safety and efficacy and the extent … During the followup period (up to 25 months) no
patient reported dysphagia recurrence, but some patients … These malignancies were reviewed by an independent safety review
board that requested no changes to