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effectivehealthcare.ahrq.gov/products/angina-heart-attack-treatments/research
November 04, 2013 - Structured Abstract
Objectives
For patients with unstable angina or non–ST elevation myocardial infarction … Patients undergoing an early invasive approach
Upstream (precatheterization) treatment using glycoprotein … Patients undergoing an initial conservative approach
In randomized trials, enoxaparin reduced composite … Further study is needed to determine the effectiveness and safety of newer agents in combination with … with diabetes, women, obese patients, and people with comorbid illness).
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effectivehealthcare.ahrq.gov/sites/default/files/cardiovascular-horizon-scan-high-impact-1412.pdf
December 01, 2014 - However, some noted insufficient information regarding long-term safety and
efficacy. … ; a long-term patient registry to determine long-
term safety; and an enhanced pharmacovigilance program … could affect physician
and patient acceptance. … Efficacy and safety of a microsomal triglyceride
transfer protein inhibitor in patients with
homozygous … Another trick to improve
the safety of transseptal puncture.
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effectivehealthcare.ahrq.gov/products/breast-cancer-imaging/research-protocol
December 17, 2013 - the accuracy, benefits and potential risks of each modality, including sensitivity and specificity, safety … What are the advantages (e.g., sensitivity and specificity) and disadvantages (e.g., safety issues, cost … Input from Key Informants will also be sought to determine safety issues that may be associated with … ; (b) health insurance policies; (c) patient preferences. … Patient Advocates
[n=3]
What factors are most important to patients regarding imaging following
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-cancer-imaging_research-protocol.pdf
December 17, 2013 - • What are the advantages (e.g., sensitivity and specificity) and disadvantages (e.g., safety
issues … patients with metastatic breast cancer. … Input from Key Informants will
also be sought to determine safety issues that may be associated with … ; (b) health insurance policies; (c)
patient preferences. … Patient Advocates
[n=3]
1.
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effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1312.pdf
December 01, 2013 - They
were especially concerned about patient motivation to use this system and thought the patients … Despite the safety and efficacy of emergency contraception (EC), its use
remains low. … Despite its safety and efficacy, EC use remains low.4 Barriers to use include lack of
knowledge or … Overall, experts concluded that
despite these obstacles, the potential for adoption by both patients … for this intervention to disrupt care processes and patient management.
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effectivehealthcare.ahrq.gov/sites/default/files/s116.pdf
October 01, 2007 - For the IV to be defined
for each patient, we excluded each physician’s first patient
from the cohort … These patients were treated by 6390
physicians. … Characteristics of Cohort
Patient Characteristics N %
Female patient 12,545 81.5
Age �80 10,750 70.0 … Indeed, in a comparative
safety study of APMs in a population of seniors in British
Columbia, Canada, … 0.78 �0.58, 1.02� 0.07
Patient of PCPs 0.98 �0.70, 1.39� 0.93
Long-acting benzodiazepines All patients
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effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_2012-12-10.pdf
January 01, 2012 - calibrating the CGM (where applicable) and
checking sensor performance as needed plus associated reagents … with T1DM, longer safety and efficacy studies are needed before they
can properly determine whether … moderately high potential for impact on the health care system, provided
additional efficacy and safety … In terms of
patient acceptance, this same expert conceded patients could be willing to accept the risk … Efficacy and
safety of exenatide once weekly versus liraglutide
in subjects with type 2 diabetes
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effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_2012-12-10.pdf
January 01, 2012 - calibrating the CGM (where applicable) and
checking sensor performance as needed plus associated reagents … with T1DM, longer safety and efficacy studies are needed before they
can properly determine whether … moderately high potential for impact on the health care system, provided
additional efficacy and safety … In terms of
patient acceptance, this same expert conceded patients could be willing to accept the risk … Efficacy and
safety of exenatide once weekly versus liraglutide
in subjects with type 2 diabetes
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-protocol-update-2023.pdf
January 01, 2023 - reporting; (4) serve as a source for clinicians seeking information on
effectiveness of interventions for patients … meditation or "mind body" or mindfulness or music or "prolonged exposure" or
relaxation or "seeking safety … meditation or "mind body" or mindfulness or music or "prolonged exposure" or
relaxation or "seeking safety … Allowed PTSD psychotherapy, other psychotherapy, and psychotropic medication indicators
12. … Patients with suicidality excluded indicator
13.
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effectivehealthcare.ahrq.gov/sites/default/files/pulmonary_hi_impact.pdf
April 01, 2012 - In a clinical trial, the effectiveness and safety of BT versus a sham procedure in patients (n = 288) … Thermoplasty System for treatment-resistant asthma
studies to investigate the system’s long-term safety … Effectiveness and safety of bronchial
thermoplasty in the treatment of severe asthma: a
multicenter … PMA P080032: FDA summary of
safety and effectiveness data (SSED) for the
Alair bronchial thermoplasty … Safety
of bronchial thermoplasty out to 5 years in
patients with severe refractory asthma: research
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effectivehealthcare.ahrq.gov/sites/default/files/ch_2-user-guide-to-ocer_130129.pdf
January 01, 2011 - Selecting the appropriate data source, patient population,
inclusion/exclusion criteria, and comparators … deemed plausible
only for unintended (usually adverse) effects
of medical interventions, that is, for safety … The design was originally
proposed for rare adverse events in vaccine safety
studies for which it seems … Comparing different treatment options for a given
patient (i.e., the same indication) is at the very … Control without separate controls:
evaluation of vaccine safety using case-only
methods.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/incident-user-design_research.pdf
May 01, 2012 - about the outcomes, clinical effectiveness, safety, and appropriateness of health care items and
services … When investigators know that a patient has used the intervention before the window chosen
to define … Pharmacoepidemiol Drug Safety
2007;16:329-36.
4. Ray WA. … Pharmacoepidemiol Drug
Safety 2006;15:81-92.
15. UKPDS Group. … Pharmacoepidemiol
Drug Safety 2004;13:695-702.
19. Hippisley-Cox J, Coupland C.
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effectivehealthcare.ahrq.gov/products/progestogens-preterm-birth/research-protocol
April 15, 2010 - associated with preterm birth represent untold distress for families, as well as significant costs to patients … 17-OHP treatment regimen is relatively modest; one study estimates it to be about $400 per treated patient … Adherence is influenced by the timing, dose, route, and interval of the progestogen given, patient factors … Adverse events may occur at any point after the treatment is received, and are affected by patient factors … factors such as specialty, and health care system factors such as cost and availability, as well as patient
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/progestogens-preterm-birth_research-protocol.pdf
June 01, 2010 - associated with preterm birth represent untold distress for
families, as well as significant costs to patients … 17-OHP
treatment regimen is relatively modest; one study estimates it to be about $400 per treated
patient … Adherence is influenced by the timing, dose, route, and interval of the progestogen
given, patient factors … Adverse events may occur at any point after the treatment is received, and are
affected by patient factors … factors such as specialty, and health care system factors such as cost and availability, as
well as patient
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_disposition-comments.pdf
April 03, 2013 - Or do some patients have
major benefit on outcome X, and other patients on outcome Y? … …"
a) Seeking Safety (SS) was designed for both genders. … The
relevant paragraph was (and
still is) in the Seeking Safety
results section titled
Prevention … We agree that this study has
some limitations that limit what
we can conclude about
seeking safety … We also changed it to “seeking
safety” rather than “safety
seeking” to be consistent with
wording
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effectivehealthcare.ahrq.gov/products/anxiety-children/research-protocol
September 13, 2016 - There is a great deal of uncertainty regarding comparative effectiveness and safety of all treatments … that are widely available and validated; which are:(patients/parent reported and clinician assessed), … What are the treatment burdens (for patients, providers, and health systems) and contextual factors ( … disorder, or separation anxiety
Animals
Adults (age ≥ 18 years)
Infants (age < 3 years)
Patients … Evidence-Based Treatments for Children and Adolescents: An Updated Review of Indicators of Efficacy and
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/mental-health-app-draft-technical-brief.pdf
June 21, 2021 - engagement in services, therapeutic relationships between
clients and providers, and treatment retention … personalized
medicine approach to mental health apps (i.e., will a specific app work for my specific client … receive an
alert about their patient's health, or they may be able to access the patient’s health indicators … personalized medicine
approach to mental health apps (i.e., will a specific app work for a specific client … Key substance use and
mental health indicators in the United States: Results from the 2019 National
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/anxiety-children_research-protocol.pdf
September 12, 2016 - There is a great deal of uncertainty regarding comparative effectiveness and safety of all
treatments … that are widely
available and validated; which are:(patients/parent reported and clinician assessed … What are the treatment burdens (for patients, providers, and health systems) and
contextual factors … specific phobias, generalized
• Animals
• Adults (age >= 18 years)
• Infants (age < 3 years)
• Patients … Evidence-Based Treatments for
Children and Adolescents: An Updated Review of Indicators of Efficacy
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
September 01, 2011 - How do the efficacy, effectiveness,
safety, and adverse effects of treatment with DMARDs
differ among … How do the efficacy, effectiveness, Insufficient Only one study—an RCT of methotrexate versus
safety, … In addition, patient-level
meta-analysis may help address this challenge. … • The need for study populations who are
representative of typical patients with JIA. … Randomized discontinuation trials
have helped to define the risk of flare in patients who
respond to
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiation-therapy-brain-metases-protocol.pdf
October 10, 2019 - Do adverse effects vary by important patient characteristics (i.e., age,
performance status, patient … The draft protocol is informed by key
informants representing patients, care givers, patient advocates … Safety of cranial radiotherapy
concurrent with tyrosine kinase inhibitors in non-small cell lung cancer … Effectiveness and safety of "real"
concurrent stereotactic radiotherapy and immunotherapy in metastatic … https://www.fda.gov/safety/reporting-serious-problems-fda/what-serious-adverse-event.