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effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1512.pdf
December 01, 2015 - Many of newly added topics
use this integrated approach, and we look forward to the generation of safety … options, experts expressed concerns about the drug’s safety profile and
best administration method … Although intravenous ketamine has
known safety risks and might require increased infrastructure or … Optimism for this
intervention’s potential was tempered by available efficacy and safety data; several … Several experts were concerned about ketamine’s adverse event profile and noted that
safety risks could
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effectivehealthcare.ahrq.gov/sites/default/files/dementia_horizon-scan-high_impact-1306-revised.pdf
July 09, 2013 - On the other hand, some thought that knowing that a patient has AD could aid planning for
patients … in terms of patient safety and care … safety and care. … They
thought that the drug’s well-known safety profile and long history of use (in diabetes) would … AD
patients.
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effectivehealthcare.ahrq.gov/sites/default/files/s143.pdf
October 01, 2007 - Chief among them is the indication for the
drug—a patient must have the condition for which the drug … In addition, a collection of less explicit character-
istics of both the patient and prescriber influence … the choice of
a particular drug for a particular patient at a particular time. … complete (it in-
cludes all variables that actually went into the prescribing
From the *Ingenix i3 Drug Safety … Seeger, PharmD, DrPH, Ingenix i3 Drug Safety, 950
Winter Street, Suite 3800, Waltham, MA 02451.
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effectivehealthcare.ahrq.gov/sites/default/files/decide16final-mortality-risk-in-copd-pts-using-theophylline.pdf
December 01, 2009 - about the outcomes, clinical effectiveness, safety, and appropriateness of health care items and
services … This finding is consistent
with other studies on the safety of ipratropium and suggests the need for … additional research on
anticholinergic safety.38-40 This finding was also consistent with a study … Future studies that capture medication use patterns, measures of
lung function, and patient-reported … The
multiple propensity score for analysis of
dose-response relationships in drug safety
studies.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-management_research.pdf
December 01, 2009 - about the outcomes, clinical effectiveness, safety, and appropriateness of health care items and
services … This finding is consistent
with other studies on the safety of ipratropium and suggests the need for … additional research on
anticholinergic safety.38-40 This finding was also consistent with a study … Future studies that capture medication use patterns, measures of
lung function, and patient-reported … The
multiple propensity score for analysis of
dose-response relationships in drug safety
studies.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
May 19, 2010 - Effectiveness of
Off-label Use of Atypical Antipsychotics reviewed the scientific evidence on the safety … risk of death
and antipsychotics drugs, and comparison of the development of adverse effects between patients … Studies that did not report any outcomes of efficacy, effectiveness, safety/adverse events, or
utilization … We will define loss to follow-up as the number of patients excluded from
efficacy analyses, expressed … as a proportion of the number of patients randomized.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/vitamin-d-calcium_research-protocol.pdf
September 13, 2013 - ) and
physicians’ increasing use of laboratory tests to assess vitamin D and calcium status among
patients … Arrow 4 indicates the association between exposure and indicators of exposure. … Arrow 3 indicates the association of indicators of exposure to clinical outcomes. … Efficacy and safety data will
be abstracted by the statistical analyst and confirmed by the co-project … Key Informants
Key Informants are the end-users of research, including patients and caregivers, practicing
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/rural-telehealth-amended-protocol.pdf
February 25, 2021 - • Population(s):
o Rural individual patients, patient families/care partners, and patient populations … behavior, and decisions such as choice of treatment
or antibiotic stewardship; Access measure and indicators … including but not limited to
time to diagnosis or time to treatment
o KQ2: Indicators and measures … KQ2:
a) Indicators and measures of uptake of telehealth
(e.g., rates of use, timing to implementation … The Rural Health Safety Net Under Pressure: Rural Hospital
Vulnerability. 2020.
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effectivehealthcare.ahrq.gov/products/preoperative-testing/research-protocol
May 14, 2013 - prior to any operative procedure under the assumption that a larger amount of information would enhance safety … complications than patients with normal ECG results. … than patients who did not. … quality of life
Patient satisfaction
Patient resources, including time and lost work
Unplanned … Effective strategy to guide pathology test ordering in surgical patients.
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effectivehealthcare.ahrq.gov/products/attention-deficit-hyperactivity-disorder/draft-comments
August 17, 2021 - Background
The Patient-Centered Outcomes Research Institute (PCORI) is partnering with AHRQ to update … What are the comparative safety and effectiveness of pharmacologic and/or nonpharmacologic treatments … What are the comparative safety and effectiveness of different monitoring strategies to evaluate the … pharmacologic agents approved by the FDA for the treatment of ADHD that have enrollment of fewer than 100 patients … studies with comparator; for diagnostic accuracy, cross-sectional studies are acceptable if they include patients
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effectivehealthcare.ahrq.gov/sites/default/files/obesity_hi_impact.pdf
April 17, 2012 - data and postmarket safety
evaluation, set forth by the U.S. … FDA expressed concerns about the long-term cardiovascular safety profile in the overweight
and obese … Experts also opined that
further studies evaluating efficacy and safety are needed. … quality of life, thus impacting patient health outcomes. … Safety and efficacy study of
EndoBarrier in subjects with type II diabetes and
obesity.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_disposition-comments.pdf
January 01, 2014 - Peer Reviewer 2 Methods The authors should consistently report separately efficacy and
safety. … This
section should be renamed “impact of clopidogrel loading on
efficacy and safety of bivalirudin … Unfortunately, we do not have individual patient-level
data available for analysis. … prospective randomized PLATelet inhibition
and patient Outcomes (PLATO) trial. … PLATelet inhibition
and patient Outcomes (PLATO) trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/04_dementia_potential_high_impact_2012-12-10.pdf
January 01, 2012 - patient safety and care … safety and care. … A diagnosis could, however, help patients and families plan for the patient’s care and safety. … Furthermore, experts thought that the drug’s well-known safety profile
and long history of use (in … AD
patients.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/insulin-analogues-disposition-081229.pdf
September 01, 2008 - Comparative Effectiveness, Safety, and Indications of Insulin Analogues in Premixed Formulations for … Comparative
Effectiveness, Safety, and Indicuations of Insulin Analogues in Premixed Formulations for … information redacted] is pleased to submit comments on the Draft Report on Comparative
Effectiveness, Safety … thank the AHRQ for the opportunity to comment on the draft report entitled Comparative
Effectiveness, Safety … 6) Page 5 and in the Executive Summary consider adding item f to key question 1: Effectiveness and safety
-
effectivehealthcare.ahrq.gov/sites/default/files/04_dementia_potential_high_impact_june_2012.pdf
January 01, 2012 - On the other
hand, some thought that knowing that a patient has AD could aid planning in terms of safety … and care of the patient … and care of the patient. … A diagnosis could, however, aid patients and families in planning for the patient’s care and safety. … AD
patients.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
March 01, 2011 - In addition to having an increased number of
medication choices, patients with type 2 diabetes often … organized these deficiencies and
recommendations using the PICOTS format for
specifying research questions: patient … Populations
Studies often employed narrow inclusion criteria,
enrolling patients at lowest risk for … complications, and
they commonly used run-in periods to avoid enrolling
patients with adverse effects … We identified the following research gaps
related to target patient populations:
1.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-256-telehealth-women-preventive-services-executive-summary.pdf
June 01, 2022 - depression, fear of partner, coercive control, self-
efficacy, post-traumatic stress disorder, and safety … For IPV interventions,
patients were slightly older (mean age of 33 years). … of
Evidence
Harms Interactive online tool Noninteractive online tool 1 RCT (231) No difference in patient … reported anxiety
using a tailored, online safety tool vs. a
static version. … marker for
publication bias) due to small numbers of trials and heterogeneity in study design
methods, patient
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
December 01, 2010 - • Patient insight into illness.
• Health-related quality of life. … • Patient satisfaction.
• Patient-reported outcomes. … psychosis
Loxapine Approved 1975 Schizophrenia
Adults
Safety and effectiveness in pediatric … Perphenazine Approved 1965 Schizophrenia
Adults
Safety and effectiveness in pediatric
patients … Adults
Pediatric use: safety & effectiveness not
established in patients <18 yrs
1. agranulocytosis
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_disposition-comments.pdf
November 20, 2014 - We are also aware that funnel plots are
poor indicators of publication bias. … Aside from the liver lesions, all of the “units”
are patients (i.e., patients being correctly
staged … Adoption of these standards benefits patient dose. … MITA’s
approach builds upon existing manufacturer safety measures –
including equipment safety standards … , protocol development,
quality and safety checks, provider education programs and
physician-developed
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/telehealth-women-draft-report.pdf
December 10, 2021 - from a
patient perspective.59 Patients who received contraceptive services via telehealth (n=86) at … Safety Behaviors
Three trials evaluated efforts to adapt safety behaviors as outcome measures.13,62,64 … safety. … safety given the ongoing pandemic. … Social distancing doesn’t mean
safety distancing. 2020.