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effectivehealthcare.ahrq.gov/products/coronary-stents-outcomes/research
February 10, 2010 - Thus we are unable to directly address some important questions which have been raised regarding the safety … Effectiveness and Safety of Drug-Eluting Stents in Ontario. N Engl J Med 2007;357:1393-1402. … Balancing Efficacy and Safety of Drug-Eluting Stents in Patients Undergoing Percutaneous Coronary Intervention … Safety and Efficacy of Sirolimus- and Paclitaxel-Eluting Coronary Stents. … Unadjusted baseline characteristics of patients in study population
Patient Characteristics
Study
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_disposition-comments.pdf
March 01, 2012 - Despite recent advances in
patient care, fatal pulmonary embolism occurs in 0.1 -
0.5% of these patients … A separate question is
whether there are patient risk factors associated with
VTE events in patients … We
propose the following rubric: 1, Efficacy; 2, Safety; 3,
Cost. … 2) Improved
Efficacy; No improvement in Safety 3) No improvement
in Efficacy; Improved Safety 4) No … Furthermore, in
the clinical trials, highly selected patient groups were
used (excluding patients felt
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effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1512.pdf
December 01, 2015 - balloon removal from
other teams’ patients (3 patients, 0.11%), and at 1 patient (0.03%) each, Wernick … Patients were
reported to have generally tolerated the balloon well, with one early removal for patient … greatly and limit patient
acceptance, although patient interest in the procedure would likely remain … Perioperative safety in the longitudinal
assessment of bariatric surgery. … Safety of antiobesity drugs. Ther Adv Drug Saf.
2013;4(4):171-81.
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-is-the-comparative-renal-of-differnt-contrast-media-used-in-radiographic-imaging-what-is-the-comparative-efficacy-of-different-therapies-in-preventing-contrast-induced-nephropathy
December 30, 2011 - the specific technologies, devices, drugs, or interventions you would like to see compared:
Renal safety … or group(s) of patients does your question apply to? … Patients undergoing coroanry angiography and interventions
Are there subgroups of patients that your … Patients with renal dysfunction Patients with diabetes
Describe the health-related benefits you … (For example, improvements in patient symptoms or problems from treatment or diagnosis.)
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
October 18, 2010 - Terbutaline sulfate is commonly used in selected patients as a maintenance
therapy to inhibit uterine … Further, as the level of
care offered to patients and the level of activity of patients on continuous … subcutaneous
terbutaline might differ from that of patients on comparative treatments, we will explore … Therefore, in addition to conducting heterogeneity analyses by other indicators of true
preterm labour … to ensure only one event is recorded per patient, in the case the
same patient experiences multiple
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/epc-making-sure-evidence-understood.pdf
July 01, 2020 - Department of Health and Human
Services that is charged with improving the quality, safety, efficiency … What information is needed to make better
recommendations to patients? … Consumers, patients,
caregivers, and patient
advocacy organizations
It is vital that research answer … with accurate, independent, scientifically rigorous information for
comparing the effectiveness and safety … Patient, Population or Problem:
◆ The “P” in PICO(TS) is a description of the patient(s) of interest
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/lysosomal-storage-diseases-therapies_research-protocol.pdf
November 15, 2012 - every other week, for the
life of the patient. … What are the potential safety issues and harms with ERT?
2. … What published and unpublished studies have reported on the use and safety of
this intervention? … Adverse events/harms/safety issues reported
4. … patient and one parent
of a child patient will be consulted.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_executive.pdf
November 01, 2012 - In patients with chronic plaque psoriasis,
what is the comparative safety of systemic biologic
agents … To be included, the patient population evaluated in the
study must have been adult patients (≥18 years … In an RCT that compared the efficacy and
safety of adalimumab with placebo in patients with
moderate … Study Evaluating the Efficacy and Safety of Etanercept and
Acitretin in Korean Patient With Moderate … Safety and
efficacy study on etanercept in patients with plaque psoriasis.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
February 01, 2018 - The workgroup suggests that EPC reviews focus on indicators of more
severe harms (e.g., “serious” adverse … 9) How should input from technical and clinical experts and patients or patient advocacy groups be
used … How should input from technical and clinical experts and patients or patient advocacy groups be
used … Had to report data from
groups of in which at least
85% of the patients were
from one of the patient … What are the
harms of therapeutic interventions
for patients with ME/CFS and how
do they vary by patient
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-selection-harms-systematic-reviews.pdf
February 01, 2018 - 2016. http://www.fda.gov/Safety/MedWatch/HowToReport/ucm053087.htm (accessed October 2, 2017)
1. … Eliciting patient perspective in patient-centered outcomes research: a meta narrative systematic review … Eliciting patient perspective in patient-centered outcomes research: a meta narrative systematic review … EPC reviews should focus on indicators of more severe harms as it is more difficult to interpret the … Eliciting patient perspective
in patient-centered outcomes research: a meta narrative systematic
review
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effectivehealthcare.ahrq.gov/products/vitamin-d-calcium/research-protocol
June 10, 2013 - states) and physicians’ increasing use of laboratory tests to assess vitamin D and calcium status among patients … Arrow 4 indicates the association between exposure and indicators of exposure. … that might include some people with diseases of concern—for example, some hypertensive and diabetic patients—will … Efficacy and safety data will be abstracted by the statistical analyst and confirmed by the co-project … Key Informants
Key Informants are the end-users of research, including patients and caregivers, practicing
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_executive.pdf
May 01, 2013 - The burden of VTE is higher among some patient
populations, including patients who have experienced … and safety of pharmacologic
strategies for VTE prevention in patients with liver disease. … effectiveness and safety of pharmacologic strategies among
patients with liver disease. … in the patient populations. … RCTs should evaluate the comparative effectiveness
and safety of LMWHs in obese patients.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment-future_research.pdf
January 01, 2014 - with patient dropouts. … retention
Patients Standardized characterization and reporting of patient and wound characteristics … It is also extremely painful to the patient. … Population
Standards for Describing Participating Patients and Their Ulcers
Reporting of patient characteristics … ,
patient-reported and other secondary outcomes.
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effectivehealthcare.ahrq.gov/sites/default/files/s131.pdf
October 01, 2007 - Presented at the Agency for Healthcare Research and Quality meeting on
“Comparative Effectiveness and Safety … competitors within a
class are often marketed for better efficacy, slightly expanded
indications, or better safety … Baseline patient characteristics are presented in Table 1. … the
effectiveness and safety of a particular drug that I am about to
start and continue to use, compared … , we identified a set of restrictions that
analysts should consider in epidemiologic studies of the
safety
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-disposition-comments.pdf
November 01, 2022 - Background
and Purpose, I disagree saying the 911 workers have contact
with the public and multiple patients … of the background section to
indicate that public-facing EMS clinicians
have contact with multiple patients … o acknowledge that exposures may result from activities
not involving direct contact with patients … ) evaluation of strategies implemented by 911 call
centers that aid in the detection of infectious patients … The
Needlestick Safety & Prevention Act of 2000 was passed by the
U.S.
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effectivehealthcare.ahrq.gov/products/patient-centered-medical-home/research-protocol
February 23, 2012 - as a way of improving patient experiences, outcomes, safety, and system efficiency. 10-12 It is based … Clinical outcomes: Intermediate patient outcomes (e.g., change in HbA1c for diabetic patients). … A systems-based approach to quality, safety, and delivery of evidence-based care. … Clinical outcomes: Intermediate patient outcomes (e.g., change in HbA1c for diabetic patients). … care, superb access to care, and a systems-based approach to quality and safety.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_executive.pdf
April 01, 2013 - KQ 2: For patients with PAH, what are the comparative
effectiveness and safety of (a) echocardiography … KQ 3: For patients with PAH, what are the comparative
effectiveness and safety of monotherapy or combination … We found no studies describing the safety (or harms) of
echocardiography or biomarker testing. … Twenty-eight RCTs involving 3,613 patients evaluated the
comparative effectiveness and safety of monotherapy … The mean patient ages ranged from 28 to 50 years old.
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effectivehealthcare.ahrq.gov/products/treatment-resistant-depression/research-protocol
December 09, 2009 - when the patient is treatment resistant. … For adults with treatment-resistant depression, do non-pharmacologic interventions differ in safety, … Comparators: ECT, rTMS, VNS, demonstrated effective psychotherapy
Outcomes for each question
Safety … KQ4 focuses on safety issues (adverse effects, adherence) with each of the interventions. … While the patient is ultimately the one to make the decision about whether to receive the non-pharmacologic
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/treatment-resistant-depression_research-protocol.pdf
December 09, 2009 - when the patient is treatment resistant. … For adults with treatment-resistant depression, do non-pharmacologic interventions differ in
safety, … Comparators: ECT, rTMS, VNS, demonstrated effective psychotherapy
• Outcomes for each question
• Safety … KQ4 focuses on safety issues (adverse effects, adherence) with
each of the interventions. … While the patient is ultimately the one to make the decision about whether to receive the non-
pharmacologic
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_8-user-guide-to-ocer_130129.pdf
October 01, 2013 - ablation for
hepatocellular carcinoma compared to resection
or no treatment5 and a comparison of the safety … Diagnoses or procedures coded for payment No Yes
Behavioral risk factors Yes* No
Diet Sometimes* No
Indicators … missing biochemistry lab data
compared to early-stage patients (6-9% incomplete in early-stage patients … Assessing
accuracy of diagnosis-type indicators for flagging
complications in administrative data. … Study
design for a comprehensive assessment of
biologic safety using multiple healthcare data
systems