-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1312.pdf
January 01, 2016 - for calibrating the
CGM (as applicable) and checking sensor performance as needed plus associated
reagents … Patients and their diabetes care
team work to adjust patient insulin dosages using feedback from a … complications would lower long-term, per-patient costs for both patients and third-
party payers. … Genentech has a patient-assistance program to help defray costs for qualified patients.175
Several … Efficacy,
safety, and tolerability of exenatide once weekly
in patients with type 2 diabetes mellitus
-
effectivehealthcare.ahrq.gov/products/vte-prophyalaxis/research
May 29, 2013 - Patients hospitalized with trauma, traumatic brain injury, burns, or liver disease; patients on antiplatelet … therapy; obese or underweight patients; those having obesity surgery; or with acute or chronic renal … Objectives
To systematically review the comparative effectiveness and safety of pharmacological and … with traumatic brain injury when compared with patients without anticoagulation. … care are associated with increased mortality and do not decrease the risk of pulmonary embolism in patients
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hip-fracture-pain.ppt
May 01, 2011 - effectiveness and safety? … Evidence about the patient subpopulation characteristics that influence effectiveness and safety was … It is important to note that no studies examined the effectiveness or safety of the most commonly used … The evidence may support continued research to test effectiveness and safety. … Influence of Subpopulation Characteristics on Effectiveness and Safety (2)
Abou-Setta AM, Beaupre LA,
-
effectivehealthcare.ahrq.gov/sites/default/files/hip-fracture-pain.ppt
May 01, 2011 - effectiveness and safety? … Evidence about the patient subpopulation characteristics that influence effectiveness and safety was … It is important to note that no studies examined the effectiveness or safety of the most commonly used … The evidence may support continued research to test effectiveness and safety. … Influence of Subpopulation Characteristics on Effectiveness and Safety (2)
Abou-Setta AM, Beaupre LA,
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/registry-of-patient-registries_research-2014_0.pdf
January 01, 2014 - clinical practice, effectiveness, safety, and quality. … Serves as a recruitment tool for researchers and patients interested in participating in
patient registries … Safety
and efficacy of rituximab in systemic lupus
erythematosus: results from 136 patients
from the … Safety and
efficacy of rituximab in systemic lupus
erythematosus: results from 136 patients
from the … Inpatient Quality Indicators #16.
Technical Specifications.
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/registry-of-patient-registries_research-2014.pdf
January 01, 2014 - clinical practice, effectiveness, safety, and quality. … Serves as a recruitment tool for researchers and patients interested in participating in
patient registries … Safety
and efficacy of rituximab in systemic lupus
erythematosus: results from 136 patients
from the … Safety and
efficacy of rituximab in systemic lupus
erythematosus: results from 136 patients
from the … Inpatient Quality Indicators #16.
Technical Specifications.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypertension-pulmonary-arterial_research-protocol.pdf
January 30, 2013 - For patients with suspected pulmonary arterial hypertension (PAH) and asymptomatic
patients at high … For patients with PAH, what is the comparative effectiveness and safety of (a)
echocardiography plus … outcomes (patient outcome efficacy)? … For patients with PAH, what is the comparative effectiveness and safety of monotherapy
or combination … Safety of biomarkers and echocardiography (bleeding, bruising, infection)
o KQ 2
1.
-
effectivehealthcare.ahrq.gov/products/diabetes-update-2015/research-protocol
January 22, 2015 - patients who cannot initiate or who cannot tolerate metformin remains unclear. … outcomes will be especially useful to clinicians, patients, investigators, guideline developers, and … Patients and patient advocates also will find the information valuable when making decisions about treatment … using a co-morbidity scale or index; by including other medical conditions or medications used by the patient … Risk of bladder cancer among patients with diabetes treated with a 15 mg pioglitazone dose in Korea:
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/vaccine-safety_research-protocol.pdf
September 18, 2012 - System
(VAERS),11 the Vaccine Safety Datalink,12 and the Clinical Immunization Safety Assessment
Network … Both
patient factors (i.e., age and race) and vaccine factors (i.e., formulation, dosage, and timing … AEs) or passive (participants are not specifically asked about or tested for the
occurrence of AEs; patient … Multiple publications are defined by the investigated patients.
F. … The Vaccine Safety Datalink: a model for monitoring
immunization safety.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_disposition-comments.pdf
August 23, 2013 - Similarly in studies that did not have access to
patient medical charts or patient interviews, how was … Similarly, a recent FDA
Drug Safety Communication that addressed
bleeding events in patients taking … In addition,
apixaban in particular showed safety and efficacy
when compared to aspirin in patients … 75) and younger patients for both
efficacy and safety. … Efficacy and
safety of rivaroxaban compared with warfarin among
elderly patients with nonvalvular atrial
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-214-afib-disposition-comments.pdf
October 30, 2019 - Efficacy and safety of dabigatran
compared to warfarin in patients with paroxysmal,
persistent, and … Recommendation: Based on the evidence, all
DOACS have shown safety and efficacy in patients
who are … The safety population is used, which is the same
population used in other DOAC trials to assess
safety … Efficacy and safety
of rivaroxaban compared with warfarin in patients
with peripheral artery disease … Efficacy and safety of
rivaroxaban compared with warfarin in patients with
carotid artery disease and
-
effectivehealthcare.ahrq.gov/products/acs-pci-adjunctive-devices/research
December 29, 2011 - . 2, 2012 Disposition of Comments Report Jun. 25, 2013 Surveillance Report Adjunctive Devices for Patients … The data comparing adjunctive devices with standard PCI (control) are predominantly in patients with … In RCTs conducted in STEMI patients, catheter aspiration devices decreased the risk of a major adverse … Due to insufficient data, the safety of these devices is unclear. … Systematic review: comparative effectiveness of adjunctive devices in patients with ST-segment elevation
-
effectivehealthcare.ahrq.gov/products/cystic-fibrosis-hgh/research-protocol
January 22, 2010 - in secondary costs per year per patient [6 ]. … However, issues arise in its clinical interpretation because of its basis on height; a CF patient with … KQ 6: In patients with CF, how is efficacy, effectiveness, safety or adverse events impacted by rhGH … KQ 7: In patients with CF, how do the efficacy, effectiveness, safety or adverse events of treatment … Patient Registry Annual Report 2006 . Bethesda, Maryland; 2008.
-
effectivehealthcare.ahrq.gov/products/weight-gain-prevention/research-protocol
October 25, 2011 - help provide an evidence base for future practice guidelines to influence individual decision making, patient … Objectives
We aim to compare the effectiveness, safety and impact on quality of life of individual … 27
Safety and effectiveness beyond 4 years have not been determined (FDA label 12/17/2010)
B. … Health Indicators Warehouse. Healthy Weight in Adults. … http://www.healthindicators.gov/Indicators/Healthyweightinadults_1207/Profile/Data .
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-205-predictors-trauma-care-disposition-comments.pdf
April 01, 2018 - These sites also need some type of triage scheme to
determine if a patient needs to go to a higher level … We have expanded the
explanation that we used several
indicators for serious injury in this
review … Very different from triage of daily occurring injuries where focus is on
a single patient. … We agree that using different
indicators of serious injury effects
the performance and we included … Doing so increases costs and risks
to personal safety.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0411_02-10-2011.pdf
January 01, 2011 - preoperative testing or alternative testing
Outcome(s): Surgical complications, morbidity, mortality, patient … experience, improved patient safety,
cost savings
Key Questions
from Nominator:
1. … (e.g., potassium in patients on diuretics, pregnancy test in
women of child-bearing age)
4. … Do routine preoperative tests change patient management decisions? … preoperative testing has been part of the screening process for appropriate preoperative
care and patient
-
effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1512.pdf
December 01, 2015 - at increased risk of
esophageal cancer and that its potential safety relative to endoscopy would be … reprocessing
of endoscopes have been recognized for several years, and FDA has published several safety … Treatments are aimed at symptomatic relief, but questions of safety and efficacy
remain. … However, other experts thought the
availability of a new IBS therapy with a seemingly good safety profile … Persistent contamination on colonoscopes and
gastroscopes detected by biologic cultures and
rapid indicators
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-loss-surgery_research-protocol.pdf
December 14, 2010 - The benefits/risks ratio in the long term is also a concern:
effectiveness and safety data are very … studies will be excluded: 1) studies that did not report any
outcomes of efficacy, effectiveness, or safety … Provisional analytic framework for evaluating the effectiveness and safety of
alternative approaches … to treatment of metabolic conditions in the patient population with BMI
below 35. … Provisional analytic framework for evaluating the effectiveness and safety of
alternative approaches
-
effectivehealthcare.ahrq.gov/products/weight-loss-surgery/research-protocol
December 14, 2010 - The benefits-to-risks ratio in the long term is also a concern: effectiveness and safety data are very … What other patient factors (social support, counseling, preoperative weight loss, compliance with recommended … Benefits and harms for specific subpopulations (by gender, age, and race/ethnicity) and other patient … studies will be excluded: 1) studies that did not report any outcomes of efficacy, effectiveness, or safety … Provisional analytic framework for evaluating the effectiveness and safety of alternative approaches
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
May 01, 2013 - The treatment
options offered to PAD patients depend
on whether the patient is asymptomatic or
symptomatic … Safety concerns
SOE=Insufficient
2 RCTs, 3,986 patients
Inconclusive evidence due to
heterogeneous … 1 patient
who underwent amputation in the 2 RCTs.
20
Table B. … 1 patient
who underwent amputation. … Safety concerns
SOE=Insufficient
5 RCTs, 282 patients
Inconclusive evidence due to heterogeneity of