-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
January 01, 2015 - patients who cannot initiate or who cannot tolerate
metformin remains unclear. … outcomes will be especially
useful to clinicians, patients, investigators, guideline developers, and … Patients and patient advocates also will find the information valuable when making decisions
about treatment … • We will exclude studies of patients with
type 1 diabetes, impaired glucose
tolerance, metabolic … using a co-morbidity scale or index; by including other medical
conditions or medications used by the patient
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hro-rapid-research.pdf
May 01, 2025 - of their care,
including communication with doctors and nurses, responsiveness of staff,
and other indicators … Toolkit To Improve Safety for Mechanically
Ventilated Patients. … Toolkit for Engaging Patients To Improve
Diagnostic Safety. … https://www.ahrq.gov/diagnostic-
safety/tools/engaging-patients-improve.html. … /diagnostic-safety/tools/engaging-patients-improve.html
https://www.ahrq.gov/diagnostic-safety/tools/
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd_executive.pdf
September 01, 2011 - are made in
the report, its conclusions should have clinical
applicability because they laid out the safety … Objective outcomes addressed include
esophagitis healing, ambulatory pH, other indicators of
reflux, … placebo
in improving asthma symptoms, nocturnal asthma, or
use of asthma medications, or in objective indicators … Administrative databases can
provide additional data for addressing long-term
safety issues. … Objective outcomes addressed include
esophagitis healing, ambulatory pH, other indicators of reflux,
-
effectivehealthcare.ahrq.gov/sites/default/files/s131.pdf
October 01, 2007 - Presented at the Agency for Healthcare Research and Quality meeting on
“Comparative Effectiveness and Safety … competitors within a
class are often marketed for better efficacy, slightly expanded
indications, or better safety … Baseline patient characteristics are presented in Table 1. … the
effectiveness and safety of a particular drug that I am about to
start and continue to use, compared … , we identified a set of restrictions that
analysts should consider in epidemiologic studies of the
safety
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_disposition-comments.pdf
August 23, 2013 - Similarly in studies that did not have access to
patient medical charts or patient interviews, how was … Similarly, a recent FDA
Drug Safety Communication that addressed
bleeding events in patients taking … In addition,
apixaban in particular showed safety and efficacy
when compared to aspirin in patients … 75) and younger patients for both
efficacy and safety. … Efficacy and
safety of rivaroxaban compared with warfarin among
elderly patients with nonvalvular atrial
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-214-afib-disposition-comments.pdf
October 30, 2019 - Efficacy and safety of dabigatran
compared to warfarin in patients with paroxysmal,
persistent, and … Recommendation: Based on the evidence, all
DOACS have shown safety and efficacy in patients
who are … The safety population is used, which is the same
population used in other DOAC trials to assess
safety … Efficacy and safety
of rivaroxaban compared with warfarin in patients
with peripheral artery disease … Efficacy and safety of
rivaroxaban compared with warfarin in patients with
carotid artery disease and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_disposition-comments.pdf
November 27, 2012 - For this reason, it is also
important to capture long-term safety to
obtain a global aspect of how … these
therapies impact patient care, both benefits
and harms. … For KQ 1, what does this patient population look like? … Efficacy and safety of infliximab vs. … One patient was reported to have hypertension in patients who
switched from methotrexate to infliximab
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
October 18, 2010 - Terbutaline sulfate is commonly used in selected patients as a maintenance
therapy to inhibit uterine … Further, as the level of
care offered to patients and the level of activity of patients on continuous … subcutaneous
terbutaline might differ from that of patients on comparative treatments, we will explore … Therefore, in addition to conducting heterogeneity analyses by other indicators of true
preterm labour … to ensure only one event is recorded per patient, in the case the
same patient experiences multiple
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1312.pdf
October 01, 2014 - DBS to the
subcallosal cingulate white matter supported the long-term safety and antidepressant efficacy … The safety of
ECT in patients with an implanted DBS system has not been established. … ketamine would have a minimal
impact on health outcomes in the absence of data on long-term effects, safety … Efficacy and safety of mifepristone for the
treatment of psychotic depression. … Neuropsychological safety of nucleus accumbens
deep brain stimulation for major depression:
effects
-
effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_2012-12-11.pdf
January 01, 2012 - data and postmarket safety evaluation—set
forth by the U.S. … Kushner and colleagues announced results from a phase III clinical trial (SEQUEL)
evaluating the safety … However, a
potential increase in per-patient cost might serve as a barrier to acceptance by some patients … While
preliminary results are promising, further studies evaluating efficacy and safety are needed, … Safety and efficacy study of
EndoBarrier in subjects with type II diabetes and
obesity.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-seniors-death_research.pdf
August 01, 2007 - Microsoft Word - ehcrr#2toCSI.doc
Effective Health Care
Number 2
Research Reports
Comparative Safety … Patients. … Older Patients. … The older patient: the ongoing challenge of
efficacy and tolerability. … The efficacy,
safety, and tolerability of antipsychotics in the
elderly.
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_1-user-guide-to-ocer_130129.pdf
August 13, 2012 - end-users and facilitates appropriate
translation of the results into health care practice
and use by patient … If the FDA
approves, human testing for safety and efficacy
can begin. … These endpoints may be
categorized as clinical endpoints, patient-reported
outcomes and quality of … On the other hand, a patient who has
a health condition where there are few treatments
may be willing … Likewise, some patient groups were
reported to be concerned by the decision since it
presumably would
-
effectivehealthcare.ahrq.gov/sites/default/files/s116.pdf
October 01, 2007 - pharmacoepidemiology, prescribing
(Med Care 2007;45: S116–S122)
Observational studies are necessary to evaluate the safety … For the IV to be defined
for each patient, we excluded each physician’s first patient
from the cohort … Characteristics of Cohort
Patient Characteristics N %
Female patient 12,545 81.5
Age �80 10,750 70.0 … Indeed, in a comparative
safety study of APMs in a population of seniors in British
Columbia, Canada, … 0.78 �0.58, 1.02� 0.07
Patient of PCPs 0.98 �0.70, 1.39� 0.93
Long-acting benzodiazepines All patients
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/lysosomal-storage-diseases-therapies_research-protocol.pdf
November 15, 2012 - every other week, for the
life of the patient. … What are the potential safety issues and harms with ERT?
2. … What published and unpublished studies have reported on the use and safety of
this intervention? … Adverse events/harms/safety issues reported
4. … patient and one parent
of a child patient will be consulted.
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1306.pdf
January 01, 2016 - for calibrating the
CGM (as applicable) and checking sensor performance as needed plus associated
reagents … But the experts called for
longer safety and efficacy studies to determine whether this system would … Genentech has a patient assistance program to help defray costs for
qualified patients.135
Several … Efficacy and safety of exenatide once weekly
versus sitagliptin or pioglitazone as an adjunct to … Efficacy,
safety, and tolerability of exenatide once weekly
in patients with type 2 diabetes mellitus
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-update_research-protocol.pdf
December 04, 2015 - Within each KQ, we will
assess outcomes for subgroups of patients or studies based on patient and clinical … (patientsafety,
effectiveness, and policy challenges. … Efficacy and safety of second-generation
antipsychotics in children and adolescents with psychotic and … Drug Safety. 2011 Aug 1;34(8):651-68. PMID: 21751826.
17.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_disposition-comments.pdf
May 01, 2013 - Disposition of Comments for Efficacy and Safety of Screening for Postpartum Depression
Comparative … Effectiveness Research Review Disposition of Comments Report
Research Review Title: Efficacy and Safety … Efficacy
and Safety of Screening for Postpartum Depression. Comparative Effectiveness Review 106. … What are community patients? … It can be considered unethical to screen
women without a safety net and protocol in place.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-executive-sum.pdf
January 01, 2024 - prescribed
cannabis (2)
Whole-plant
cannabis,
“certified 12.5%
THC” (CBD NR)
route determined
by patient … final
mean dose 16.6/15.4
mg THC/CBD/day vs.
17.2 mg THC/day
None specified; based
on individual patient … a Patients could choose any medicinal product they preferred in these studies. … Pharmacokinetics and pharmacodynamics of
cannabis-based medicine in a patient
population included in … Cannabis for chronic pain: cardiovascular
safety in a nationwide Danish study.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hro-protocol.pdf
January 01, 2023 - stakeholders, clinical specialists, experts in patient
safety issues, and a patient/consumer perspective … groups
6
Study Parameter Inclusion criteria Exclusion criteria
• Patients receiving
care … /products/prioritization-patient-safety-practices
https://effectivehealthcare.ahrq.gov/products/prioritization-patient-safety-practices … The TEP included 15 experts in patient safety with representa... … To accomplish that task, we will review AHRQ’s Patient Safety Networ...
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
June 04, 2010 - • The following outcomes were added: patient or parent/caregiver preferences, work-related
functional … outcomes, patient insight into illness. … followup), patient baseline characteristics (diagnosis and age at diagnosis, age, sex, race,
weight … in each group, and the number of patients affected. … Adults
Pediatric use: safety & effectiveness not
established in patients <18 yr
1. agranulocytosis