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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
November 01, 2017 - arrest, function, quality of life,
other clinical sequelae of opioid overdose; health care
utilization indicators … National Highway Traffic Safety Administration. The national
EMS scope of practice model. … Joint meeting of the anesthetic and analgesic
drug products and the drug safety and risk management … Joint meeting
of anesthetic and analgesic drug products advisory
committee and drug safety and risk … Randomized controlled
trial comparing the effectiveness and safety of intranasal and
intramuscular
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
May 19, 2010 - Effectiveness of
Off-label Use of Atypical Antipsychotics reviewed the scientific evidence on the safety … risk of death
and antipsychotics drugs, and comparison of the development of adverse effects between patients … Studies that did not report any outcomes of efficacy, effectiveness, safety/adverse events, or
utilization … We will define loss to follow-up as the number of patients excluded from
efficacy analyses, expressed … as a proportion of the number of patients randomized.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hip-fracture-pain.ppt
May 01, 2011 - effectiveness and safety? … Evidence about the patient subpopulation characteristics that influence effectiveness and safety was … It is important to note that no studies examined the effectiveness or safety of the most commonly used … The evidence may support continued research to test effectiveness and safety. … Influence of Subpopulation Characteristics on Effectiveness and Safety (2)
Abou-Setta AM, Beaupre LA,
-
effectivehealthcare.ahrq.gov/sites/default/files/hip-fracture-pain.ppt
May 01, 2011 - effectiveness and safety? … Evidence about the patient subpopulation characteristics that influence effectiveness and safety was … It is important to note that no studies examined the effectiveness or safety of the most commonly used … The evidence may support continued research to test effectiveness and safety. … Influence of Subpopulation Characteristics on Effectiveness and Safety (2)
Abou-Setta AM, Beaupre LA,
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1412.pdf
December 01, 2014 - were uncertain regarding long-term safety and efficacy. … The yearly cost per patient would be about $13,000 at current pricing. … , which has yet to be established in this
patient population. … declining because of
safety concerns. … for similar reasons, but mentioned long-term safety as a concern.
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1412.pdf
December 01, 2014 - Adoption could be limited by ketamine’s
cost, inconsistent clinical trial data, and safety risks, multiple … But one expert with a research
5
background, citing ketamine’s safety risk and lack of long-term … be limited; these experts cited ketamine’s safety risks and lack of robust clinical
trial data as … In
contrast, scopolamine’s known safety profile and possible oral and patch delivery options, bolstered … A
study to evaluate the safety and efficacy of
intranasal esketamine in treatment-resistant
depression
-
effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1512.pdf
December 01, 2015 - at increased risk of
esophageal cancer and that its potential safety relative to endoscopy would be … reprocessing
of endoscopes have been recognized for several years, and FDA has published several safety … Treatments are aimed at symptomatic relief, but questions of safety and efficacy
remain. … However, other experts thought the
availability of a new IBS therapy with a seemingly good safety profile … Persistent contamination on colonoscopes and
gastroscopes detected by biologic cultures and
rapid indicators
-
effectivehealthcare.ahrq.gov/sites/default/files/s16.pdf
October 01, 2007 - evidence is centered on the protocol-driven ran-
domized trials, which the FDA requires to establish safety … information from
industry-funded trials may remain unpublished, limiting the
ability to examine potential safety … carefully studied in trials (especially rare or
slow emerging harms); explore sources of heterogeneity in
safety … may depend on severity of
strokes, patient preferences. … patients; audits could examine the rates at which
women and patients over age 80 are undergoing surgery
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ischemic-stroke-treatment_executive.pdf
January 01, 2011 - report: author identification,
year of publication, study design characteristics, study
population, patient … different types of
neurothrombectomy devices, what are the
type(s) of devices, study designs and sizes,
patient … patient discharge. … We did not draw conclusions
regarding their effectiveness or safety. … the topic, including randomized
controlled trials to determine the optimal device(s) to
use, and the patient
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_6-user-guide-to-ocer_130129.pdf
October 30, 2012 - alternatives
Clinical Outcomes:
Medical events that occur as a
result of disease or treatment
Clinical Indicators … thrombosis (ST)], and two relating to both safety
and effectiveness [composite of death, MI, ST, … The safety-only definition of MACE
yielded a hazard ratio of 1.75 (p<0.05), indicating
that patients … This construct
comprises outcomes from the patient perspective
and are measured by asking the patient … using clozapine may appear to have a worse safety
profile with respect to this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/study-design-considerations-chapter-2.pptx
January 01, 2013 - Cohort design has the potential to increase efficiency
Well suited for rare adverse events in vaccine safety … The design was originally proposed for rare adverse events in vaccine safety studies for which it seems … Regardless of the design chosen, selection of appropriate data source(s), the patient population, inclusion … Regardless of the design chosen, selection of appropriate data source(s), the patient population, inclusion … Regardless of the design chosen, selection of appropriate data source(s), the patient population, inclusion
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-203-adhd-disposition-comments.pdf
January 01, 2018 - In my assessment, post-marketing
surveillance studies of effectiveness and safety are badly
missing … These outcomes were seen as
being both patient-centered and most
critical for decisionmaking across … Effectiveness,
safety, and tolerability of
lisdexamfetamine dimesylate in children with attention- … A long-term o pen-label
safety and effectiveness trial of lisdexamfetamine dimesylate in
adolescents … Atomoxetine
improves patient and family coping in attention
deficit/hyperactivity disorder: a randomized
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1412.pdf
January 01, 2015 - for calibrating the
CGM (as applicable) and checking sensor performance as needed plus associated
reagents … Summary of safety and effectiveness data
(SSED). MiniMed 530G system. P120010. … Important safety information: Animas Vibe
insulin pump and CCGM system. [internet]. … Available:
http://www.animas.com/safety.
27. … A study of the safety and efficacy of a
new treatment for diabetic macular edema.
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1312.pdf
January 01, 2016 - for calibrating the
CGM (as applicable) and checking sensor performance as needed plus associated
reagents … Patients and their diabetes care
team work to adjust patient insulin dosages using feedback from a … complications would lower long-term, per-patient costs for both patients and third-
party payers. … Genentech has a patient-assistance program to help defray costs for qualified patients.175
Several … Efficacy,
safety, and tolerability of exenatide once weekly
in patients with type 2 diabetes mellitus
-
effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1412.pdf
December 01, 2014 - Experts wanted to see additional clinical trial data assessing
baclofen’s long-term safety and efficacy … solution to a reference
product; a user experience study with adult and juvenile volunteers; and a safety … All adult volunteers, and 15 of 19 adolescent volunteers,
successfully used Evzio, removing the safety … to patients’ families that it be available for emergency use at home. … ,
and patients’ families, the experts concluded.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypertension-pulmonary-arterial_research-protocol.pdf
January 30, 2013 - For patients with suspected pulmonary arterial hypertension (PAH) and asymptomatic
patients at high … For patients with PAH, what is the comparative effectiveness and safety of (a)
echocardiography plus … outcomes (patient outcome efficacy)? … For patients with PAH, what is the comparative effectiveness and safety of monotherapy
or combination … Safety of biomarkers and echocardiography (bleeding, bruising, infection)
o KQ 2
1.
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-child-adolesc-mental-health-grand-rounds.pptx
May 22, 2025 - ; that all scientific research used in support or justification of a patient care recommendation will … The Patient-Centered Outcomes Research Institute® (PCORI®) funded the report. … The Patient-Centered Outcomes Research Institute® (PCORI®) funded the report. … family-expressed emotion or family criticism, familial hostility, or familial overinvolvement directed towards the patient … latency age and young adults, externalizing disorders, neurodiversity, diverse populations
Collect patient
-
effectivehealthcare.ahrq.gov/sites/default/files/s131.pdf
October 01, 2007 - Presented at the Agency for Healthcare Research and Quality meeting on
“Comparative Effectiveness and Safety … competitors within a
class are often marketed for better efficacy, slightly expanded
indications, or better safety … Baseline patient characteristics are presented in Table 1. … the
effectiveness and safety of a particular drug that I am about to
start and continue to use, compared … , we identified a set of restrictions that
analysts should consider in epidemiologic studies of the
safety
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/registry-of-patient-registries_research-2014.pdf
January 01, 2014 - clinical practice, effectiveness, safety, and quality. … Serves as a recruitment tool for researchers and patients interested in participating in
patient registries … Safety
and efficacy of rituximab in systemic lupus
erythematosus: results from 136 patients
from the … Safety and
efficacy of rituximab in systemic lupus
erythematosus: results from 136 patients
from the … Inpatient Quality Indicators #16.
Technical Specifications.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
January 01, 2015 - patients who cannot initiate or who cannot tolerate
metformin remains unclear. … outcomes will be especially
useful to clinicians, patients, investigators, guideline developers, and … Patients and patient advocates also will find the information valuable when making decisions
about treatment … • We will exclude studies of patients with
type 1 diabetes, impaired glucose
tolerance, metabolic … using a co-morbidity scale or index; by including other medical
conditions or medications used by the patient