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effectivehealthcare.ahrq.gov/products/preterm-birth-terbutaline-pump/research-protocol
August 05, 2010 - Terbutaline sulfate is commonly used in selected patients as a maintenance therapy to inhibit uterine … Further, as the level of care offered to patients and the level of activity of patients on continuous … subcutaneous terbutaline might differ from that of patients on comparative treatments, we will explore … Therefore, in addition to conducting heterogeneity analyses by other indicators of true preterm labour … to ensure only one event is recorded per patient, in the case the same patient experiences multiple events
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effectivehealthcare.ahrq.gov/sites/default/files/s96.pdf
October 01, 2007 - Findings
from NEISS-CADES can help design and prioritize patient safety
interventions for outpatient … Commission before dissemination of
results to patients, clinicians, and public health practitioners. … In
February and March 2006, 2 FDA Drug Safety Advisory
Panels addressed the safety of stimulant drugs … Con-
sumer Product Safety Commission; March 2000.
10. … Adverse drug events
in emergency department patients. Ann Emerg Med. 2002;39:258–267.
28.
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
June 01, 2014 - surgery, but choose to decline due to safety concerns. … for similar reasons, but mentioned long-term safety to be a concern. … health, many expressed concerns regarding long-term safety and efficacy. … data and postmarket safety evaluation—set
forth by FDA. … potential impact on patient health.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-256-telehealth-women-disposition-comments.pdf
June 16, 2022 - reported outcomes, patient satisfaction in care and patient adherence
to visits via telehealth approaches … decision aid rather than
safety planning? … Both qualitative and
patient reported outcomes are
included. … The outcomes is increased use of helpful safety
behaviors, not simply increase use of safety behaviors … Patients boycotted.
-
effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1406.pdf
January 01, 2020 - Experts wanted to see additional clinical trial data assessing
baclofen’s long-term safety and efficacy … Additionally, safety reporting from a bioavailability study in healthy volunteers
noted similar adverse … All adult volunteers, and 15 of 19 adolescent
volunteers were able to successfully remove the safety … The devices are not intended for laypersons and do not appear to have the audible
instructions, LED indicators … or increased risk of opioid
overdose.45 Overall, experts noted that because of Evzio’s extensive safety
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/vte-prophyalaxis_research-protocol.pdf
March 01, 2011 - There is clinical uncertainty about the
optimal choice of VTE prophylaxis in this patient population … This CER will evaluate the comparative effectiveness and safety of
pharmacologic prophylaxis among patients … What is the comparative effectiveness and safety of IVC filters to prevent PE in hospitalized
patients … and individual patient risk factors. … Deep-vein thrombosis: advancing awareness to protect patient lives.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-health-app-protocol-updated.pdf
January 01, 2018 - researchers, health care providers,
informaticians and technologists, app developers, as well as patient … We plan to have a separate call for patient/caregiver KI at the start of the
project, with questions … /clients and health care providers;
security and privacy features such as data usage and sharing of … Key substance
use and mental health indicators in the United States: Results from the 2019 National … how it works, how it is currently
used or might be used, and which features may be important from a patient
-
effectivehealthcare.ahrq.gov/products/crohns-disease/research-protocol
September 01, 2010 - Our proposal will address these aims, as well as the safety and patient-reported outcomes representing … We aim to compare the effectiveness, safety and patient-reported outcomes representing quality of life … The patient-reported outcomes will also help patients and caregivers to take into consideration the implications … Objectives
We aim to compare the effectiveness, safety and patient-reported measures of individual … Because safety is an important issue and safety information may not always be reported by disease severity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-assessment-research-updates_research.pdf
September 15, 2008 - In doing so, CERs more closely parallel the decisions facing clinicians, patients and
policymakers, … • Has there been a change in scope (e.g., new patient populations, new outcomes)? … Comparative Effectiveness of Epoetin and Darbepoetin for Managing Anemia in
Patients Undergoing Cancer … of medical, surgical, and
endoscopic treatments for improving objective and subjective outcomes in patients … Yes/No Yes/No Yes/No
7
10 percent to 65 percent of surgical
patients still require medications
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
September 01, 2012 - associated
with preterm birth represent untold
distress for families, as well as significant
costs to patients … However, these groups also note interest
in assessing long-term safety because the
Effective
Health … How do the effectiveness, adverse effects, and safety
of progestogen treatment differ based on the maternal … How do the effectiveness, acceptability, adherence,
adverse effects, and safety of progestogen treatment … One survey
addressed patient demand; 63 percent reported that patients
“never request”; 35 percent,
-
effectivehealthcare.ahrq.gov/products/mental-health-apps/protocol
May 03, 2021 - health researchers, health care providers, informaticians and technologists, app developers, as well as patient … We plan to have a separate call for patient/caregiver KI at the start of the project, with questions … /clients and health care providers; security and privacy features such as data usage and sharing of data … Key substance use and mental health indicators in the United States: Results from the 2019 National Survey … how it works, how it is currently used or might be used, and which features may be important from a patient
-
effectivehealthcare.ahrq.gov/products/observational-research-scores/research
May 15, 2012 - In observational studies assessing beneficial (effectiveness) or adverse (safety) outcomes, confounding … medications, 10 diagnostic groups for hospital discharges, 10 diagnostic groups for outpatient visits, and 10 indicators … A common question in pharmacoepidemiologic studies of drug safety is whether the risk conferred by a … Pharmacoepidemiology and Drug Safety 2008;17:546-555. … Pharmacoepidemiol Drug Safety 2005;14(7):465-76.
-
effectivehealthcare.ahrq.gov/products/psoriasis-chronic/research-protocol
September 27, 2011 - the main research gaps identified in this meta-analysis was the lack of comparative effectiveness and safety … To date, no comparative effectiveness review comparing the effectiveness and safety of FDA-approved biologic … Question 2
In patients with chronic plaque psoriasis, what is the comparative safety of systemic biologic … followup), patient baseline characteristics (including whether the patient is naïve to biologic therapy … We will also conduct subgroup analyses based on the patient population evaluated, including patients
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1406.pdf
June 01, 2014 - Preliminary data for these interventions
are promising, and ongoing trials are clarifying the safety … Results and Discussion of Comments
Seven experts, with clinical, research, patient safety, and health … widespread, if data support its efficacy and safety, the experts thought. … Investigators reported high
patient adherence (81% and 94%; adherence defined as patients completing … that SPARX could positively affect patient health outcomes
by providing an alternative for patients
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/multinational-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - This, in turn, may affect the perceived effectiveness or
safety of the product if the registry does … Drug Safety. 2015 January
1;38(1):13-5.
4. Elger B, Biller-Andorno N, Mauron A, et al. … http://www.fda.gov/downloads/Drugs/Drug
Safety/ucm089809.pdf. Accessed January
10, 2017.
21. … Direct-to-patient research: piloting a new
approach to understanding drug safety
during pregnancy. … Balancing the Interests of Patient Data
Protection and Medication Safety
Monitoring in a Public-Private
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/multinational-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - This, in turn, may affect the perceived effectiveness or
safety of the product if the registry does … Drug Safety. 2015 January
1;38(1):13-5.
4. Elger B, Biller-Andorno N, Mauron A, et al. … http://www.fda.gov/downloads/Drugs/Drug
Safety/ucm089809.pdf. Accessed January
10, 2017.
21. … Direct-to-patient research: piloting a new
approach to understanding drug safety
during pregnancy. … Balancing the Interests of Patient Data
Protection and Medication Safety
Monitoring in a Public-Private
-
effectivehealthcare.ahrq.gov/products/type-2-diabetes-medications-update/research-protocol
April 05, 2010 - Protocol Mar. 15, 2011 Systematic Review May. 27, 2014 Surveillance Report Comparative Effectiveness and Safety … Timing
We will include studies if patients have been on the medications for at least 3 months. … Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: A meta-analysis … controlled trial; TG = triglycerides
Population and condition of interest
All studies included patients … We excluded studies that evaluated only patients with type I diabetes, impaired glucose tolerance, metabolic
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children-future_research.pdf
February 01, 2012 - A disadvantage
of this over individual patient
randomization is that outcomes
for patients from a … A
disadvantage of this over
individual patient
randomization is that
outcomes for patients from a … post-ASCR
EFS 1 patient died of toxicity
at 3 months follow up. 5
patients were DOD at 5-
21 months … (70%),
partial remission in 1
patient (2%) and stable
disease in 13 patients
(28%). … with high-risk solid
tumors
Safety/Efficacy
study
30 patients (up
to 30 years of
age)
6/2006
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/type-2-diabetes-medications-update_research-protocol.pdf
April 06, 2010 - Timing
We will include studies if patients have been on the medications for at least 3 months. … control with sulphonylureas or insulin compared with conventional
treatment and risk of complications in patients … Pioglitazone and risk of cardiovascular events in
patients with type 2 diabetes mellitus: A meta-analysis … Inclusion and exclusion criteria
Population and condition
of interest
□ All studies included patients … We excluded
studies that evaluated only patients with type I diabetes, impaired glucose tolerance, metabolic
-
effectivehealthcare.ahrq.gov/products/insulin-blood-sugar-2010/research-protocol
June 02, 2011 - 2013 Disposition of Comments Report Feb. 16, 2016 Surveillance Report Comparative Effectiveness and Safety … However, the relative contribution of each of these factors to the disease course varies by patient. … rt-CGM differs from retrospective CGM in that it provides blood glucose feedback data to the patient … In addition, several other factors appear to be especially relevant, including the age of the patient … information about device use (e.g., analyses based on adherence to wearing the device, training of patient