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effectivehealthcare-admin.ahrq.gov/products/single-group-studies/white-paper
November 01, 2017 - EHC
The Evidence-based Practice Centers
The Scientific Resource Center
Registry of Patient … Aug 05, 2024
Making Healthcare Safer IV: Programs for Responding to Harms Experienced by Patients … Protocol
Aug 02, 2024
Making Healthcare Safer IV: High Reliability Organization (HRO) as a Patient … Safety Practice
Page last reviewed November 2017
Page originally
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/phenylketonuria_research-protocol.pdf
March 29, 2011 - dopamine in
the brain.16,17 Despite potential benefits, there is uncertainty about the efficacy and safety … of the long-term use of LNAAs and the target patient population, including the
appropriateness of … with PKU that merit
further study.5 Like pregnant women, safety and efficacy of the use of sapropterin … Primary outcomes in patient
1. … Primary outcomes in patient
1. Decreasing Phe levels in the blood
2.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cancer-radiation_technical-brief.pdf
November 01, 2009 - Type of cancer and patient eligibility criteria
3.b. … For many patients in whom a whole region has to be irradiated (e.g., the
whole pelvis in some patients … For example, in patients with glial tumors it
ranged from 5 to 39 months, whereas in patients with … Types of cancer and patient eligibility criteria
3.b. … Adverse events, harms, and safety issues reported
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effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/what-is-the-comparative-renal-of-differnt-contrast-media-used-in-radiographic-imaging-what-is-the-comparative-efficacy-of-different-therapies-in-preventing-contrast-induced-nephropathy
November 01, 2017 - EHC
The Evidence-based Practice Centers
The Scientific Resource Center
Registry of Patient … the specific technologies, devices, drugs, or interventions you would like to see compared:
Renal safety … Patients undergoing coroanry angiography and interventions
Are there subgroups of patients that your … Patients with renal dysfunction Patients with diabetes
Describe the health-related benefits you … (For example, improvements in patient symptoms or problems from treatment or diagnosis.)
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effectivehealthcare-admin.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1506.pdf
June 01, 2015 - Experts cited the cost, need for daily injections, and unknown long-term safety
profile as potential … Patients were reported to have generally tolerated the balloon
well, with one early removal for patient … .”38 However, two experts anticipated lower patient acceptance.37,42 One
clinical expert stated, “Patients … Perioperative safety in the longitudinal
assessment of bariatric surgery. … Safety of antiobesity drugs. Ther Adv Drug Saf.
2013;4(4):171-81.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-217-infertility-evidence-summary.pdf
May 01, 2019 - Management of Infertility Evidence Summary
Purpose of Review
Evaluate the comparative effectiveness and safety … Different treatments also carry different safety
risks. … What are the comparative safety and
effectiveness of available treatment strategies for
women with … o Donor
• ART
o Patient
o Donor
Intermediate
Outcomes
• Time to
pregnancy
Adverse Effects-Patient … Clomiphene
Live birth (any/
patient)
2 RCTs44,85 (909)
1 SR (9 studies,
1783 patients)103
Improvement
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effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/impact-healthcare-algorithms-racial-ethnic-disparities-March-3.pdf
July 01, 2023 - function
Novel risk prediction algorithm for postpartum depression
Replaced race with biological indicators … Example: an algorithm to distinguish between malignant and benign
moles trained on light-skinned patients … around 6 core goals: accountability,
standard, v2: general transparency, fairness, reliability and safety … standardized health data and
AHRQ’s efforts to effectively use those data to improve the quality and
safety … of patient care
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/phenylketonuria_surveillance.pdf
January 15, 2013 - 2013
Key Findings:
• All conclusions for KQ1-7 are still considered
valid
• No new significant safety … Is the portion of the CER that is
probably or certainly out of date an issue of safety (a drug withdrawn … What is the Effectiveness of BH4 in Patients with PKU? … Efficacy and safety of BH4 before the age of
4 years in patients with mild
phenylketonuria. … What is the Effectiveness of BH4 in Patients with PKU?
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effectivehealthcare-admin.ahrq.gov/products/allergy-seasonal/research-protocol
December 01, 2020 - EHC
The Evidence-based Practice Centers
The Scientific Resource Center
Registry of Patient … symptoms. 2 However, the new scheme is not interchangeable with the traditional one, as different patient … Efficacy and safety beyond 3 weeks in patients with SAR have not been established. 32
Intranasal mast … The safety of intranasal decongestants during pregnancy has not been studied. … for patients with mild symptoms.
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effectivehealthcare-admin.ahrq.gov/products/methods-guidance-harms/methods
May 01, 2020 - Observational studies based on patient registries. … Completeness of safety reporting in randomized trials: an evaluation of 7 medical areas. … Registries for evaluating patient outcomes: a user's guide. AHRQ Publication NO. 07-EHC001-1. … Drug Safety 2004;27(6):411-420.
61. Martin RCG, Brennan MF, Jacques DP. … Safety
Substantive evidence of an absence of harm.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ehc-research-gaps-telehealth.pdf
April 01, 2023 - • Some patients perceive telehealth as a barrier to
improved health outcomes owing to the absence … • P-P telehealth to support direct patient care may
provide benefits for in patient care, for neonates … Interventions
• Studies to determine the optimal structure and
safety for routine and alternative … , and
are cost-effective for the health system, patients,
and their caregivers. … depression, fear of partner, coercive control,
self-efficacy, post-traumatic stress disorder, and
safety
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/medicine-safety-call-center_research.pdf
September 01, 2007 - safety system.
4. … with the patients consent. … For patients who are not already
in the system, a basic patient information questionnaire is used to … For example, CVS required
the patients to give their categorical affirmative response before patient … Menachemi N, Burke D, Brooks RG. (2004) "Adoption factors associated with patient
safety-related information
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effectivehealthcare-admin.ahrq.gov/sites/default/files/it-architecture-for-post-marketing-surveillance-arizona-cert.pdf
September 01, 2007 - safety system.
4. … with the patients consent. … For patients who are not already
in the system, a basic patient information questionnaire is used to … For example, CVS required
the patients to give their categorical affirmative response before patient … Menachemi N, Burke D, Brooks RG. (2004) "Adoption factors associated with patient
safety-related information
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
November 01, 2008 - Observational studies based on patient registries. … Celecoxib Long-term Arthritis Safety Study
[see comment]. … http://www3.niaid.nih.gov/research/resource
s/DAIDSClinRsrch/Safety/. … Rather, adverse events are identified based on patient reports made on their
own initiative. … Safety Substantive evidence of an absence of harm.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
November 01, 2008 - Observational studies based on patient registries. … Celecoxib Long-term Arthritis Safety Study
[see comment]. … http://www3.niaid.nih.gov/research/resource
s/DAIDSClinRsrch/Safety/. … Rather, adverse events are identified based on patient reports made on their
own initiative. … Safety Substantive evidence of an absence of harm.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/congestive-heart-failure-medicines_research.pdf
March 01, 2010 - about the outcomes, clinical effectiveness, safety, and appropriateness of health care items and
services … Patient Population
We used the set of ICD-9 codes proposed for use in performance measures for HF10 … , we added indicators of the time of initiation of H-ISDN following HF
diagnosis. … Effective Health Care Research Report Number 19
3
Results
Baseline Patient Characteristics … Selection of patient population
EXCLUDE PATIENTS WITH
PREVALENT
HEART FAILURE4
PREVALENT
HEART FAILURE
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_disposition-comments.pdf
January 01, 2011 - uptake of the former two tests will result
in any significant improvement in intermediate outcomes,
safety … Safety has not been shown in the studies
comparing these biomarkers. … biomarkers in diagnosing iron deficiency, I do not
believe that necessarily predicts response to iron, safety … We agree with safety concerns, and problems of our draft
conclusion. … Since most CKD
patients (and nearly all ESRD) patients don’t respond to
oral iron focus would be mostly
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effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
March 01, 2022 - https://effectivehealthcare.ahrq.gov/products/safety-vaccines/research
7
Automated-Entry Patient-Generated … for patients, implementation of an opioid
safety initiative, provision of patient information
and … adaptations
of the ACCESS model) may improve system-level
markers, including guideline-based quality
indicators … Direct patient care strategies are
those that directly inform the patients’ own treatment
decisions … Evidence Gaps
Study Populations
• With the exception of critically ill patients, studies
of patient
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effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/for-low-risk-women-delivering-a-full-term-baby-vaginally-what-is-the-comparative-effectiveness-of-the-use-of-nitrous-oxide-for-pain-management-versus-an-epidural-or-other-pain-management-strategies-what-are-the-effects-on-th
November 01, 2017 - EHC
The Evidence-based Practice Centers
The Scientific Resource Center
Registry of Patient … What patients or group(s) of patients does your question apply to? … Are there subgroups of patients that your question might apply to? … (For example, improvements in patient symptoms or problems from treatment or diagnosis.) … There is currently controversy in the US over the effectiveness and safety of nitrous oxide in delivery
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/c-diff-infections-surveillance-140925.pdf
January 01, 2014 - • There are no new significant safety concerns. … .4,6,8,10,13,15,17,18,20,21,24,26,29,34,38,42,44,45,49
Health Canada recalled
the Xpert C. difficile assay
in 2012 because some
reagents … Notably, 21% of
EIA-negative patients presented with severe CDI,
including one patient who died of … Weiss et 2012 Safety analysis A total of 728 adults 116 healthy N/A; tolerability, In this safety analysis … , with a safety profile
comparable with oral vancomycin.