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Showing results for "patient safety indicators".
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401. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pulmonary_hi_impact.pdf
     April 01, 2012 - In a clinical trial, the effectiveness and safety of BT versus a sham procedure in patients (n = 288) … Thermoplasty System for treatment-resistant asthma studies to investigate the system’s long-term safety … Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: a multicenter … PMA P080032: FDA summary of safety and effectiveness data (SSED) for the Alair bronchial thermoplasty … Safety of bronchial thermoplasty out to 5 years in patients with severe refractory asthma: research

402. DEcIDE 32: The Incident User Design in Comparative Effectiveness Research (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/incident-user-design_research.pdf
     May 01, 2012 - about the outcomes, clinical effectiveness, safety, and appropriateness of health care items and services … When investigators know that a patient has used the intervention before the window chosen to define … Pharmacoepidemiol Drug Safety 2007;16:329-36. 4. Ray WA. … Pharmacoepidemiol Drug Safety 2006;15:81-92. 15. UKPDS Group. … Pharmacoepidemiol Drug Safety 2004;13:695-702. 19. Hippisley-Cox J, Coupland C.

403. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/progestogens-preterm-birth_research-protocol.pdf
     June 01, 2010 - associated with preterm birth represent untold distress for families, as well as significant costs to patients … 17-OHP treatment regimen is relatively modest; one study estimates it to be about $400 per treated patient … Adherence is influenced by the timing, dose, route, and interval of the progestogen given, patient factors … Adverse events may occur at any point after the treatment is received, and are affected by patient factors … factors such as specialty, and health care system factors such as cost and availability, as well as patient

404. Disposition of Comments for Psychological Treatments and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder (PTSD) (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_disposition-comments.pdf
     April 03, 2013 - Or do some patients have major benefit on outcome X, and other patients on outcome Y? … …" a) Seeking Safety (SS) was designed for both genders. … The relevant paragraph was (and still is) in the Seeking Safety results section titled Prevention … We agree that this study has some limitations that limit what we can conclude about seeking safety … We also changed it to “seeking safety” rather than “safety seeking” to be consistent with wording

405. Pain | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/pain?page=2
     August 23, 2012 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … Disease Research Protocol Archived August 5, 2010 Comparative Effectiveness and Safety … 2006 Report Research Protocol Archived August 5, 2010 Technical Brief: Use and Safety … of Positional MRI in the Management of Patients with Musculoskeletal Pain Research Protocol

406. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
     September 01, 2011 - How do the efficacy, effectiveness, safety, and adverse effects of treatment with DMARDs differ among … How do the efficacy, effectiveness, Insufficient Only one study—an RCT of methotrexate versus safety, … In addition, patient-level meta-analysis may help address this challenge. … • The need for study populations who are representative of typical patients with JIA. … Randomized discontinuation trials have helped to define the risk of flare in patients who respond to

407. Anxiety in Children (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/anxiety-children_research-protocol.pdf
     September 12, 2016 - There is a great deal of uncertainty regarding comparative effectiveness and safety of all treatments … that are widely available and validated; which are:(patients/parent reported and clinician assessed … What are the treatment burdens (for patients, providers, and health systems) and contextual factors … specific phobias, generalized • Animals • Adults (age >= 18 years) • Infants (age < 3 years) • Patients … Evidence-Based Treatments for Children and Adolescents: An Updated Review of Indicators of Efficacy

408. Research Protocol: Radiation Therapy for Brain Metastases (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/radiation-therapy-brain-metases-protocol.pdf
     October 10, 2019 - Do adverse effects vary by important patient characteristics (i.e., age, performance status, patient … The draft protocol is informed by key informants representing patients, care givers, patient advocates … Safety of cranial radiotherapy concurrent with tyrosine kinase inhibitors in non-small cell lung cancer … Effectiveness and safety of "real" concurrent stereotactic radiotherapy and immunotherapy in metastatic … https://www.fda.gov/safety/reporting-serious-problems-fda/what-serious-adverse-event.

409. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1506.pdf
     June 01, 2015 - Novartis Pharmaceuticals. 16 week efficacy and 2 year long term safety and efficacy of secukinumab … Novartis Pharmaceuticals. 16 week efficacy and 5 year long term efficacy, safety and tolerability … anti-interleukin-17a monoclonal antibody, improves active psoriatic arthritis: 24-week efficacy and safety … antibody, improves active psoriatic arthritis and inhibits radiographic progression: efficacy and safety … 17a-monoclonal-antibody-improves-active-psoriatic-arthritis-and-inhibits-radiographic-progression-efficacy-and-safety-data-from-a-phase

410. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis_research-protocol.pdf
     June 06, 2011 - From the MCG machine, five ECG wires with electrodes are attached to the patient at the four standard … KQ 4: Are there significant safety concerns/risks (i.e., radiation exposure, access site complications … relief, and quality of life in the population of interest) (KQ 3); and whether there are significant safety … collect demographics and data needed to determine outcomes (intermediate outcomes, health outcomes, and safety … The safety outcomes will be framed to help identify radiation exposure, contrast agent-induced nephropathy

411. FRN 41 - Noninvasive Technologies for the Diagnosis of Coronary Artery Disease in Women: Future Research Needs (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis-future_research_1.pdf
     February 01, 2013 - Recommended study design: an observational study of patients with varying patient risk profiles. … Safety concerns Insufficient 13 studies (9 good quality, 4 fair) reported data pertinent to safety … Patient Advocate We identified a patient advocate to represent the research priorities and issues from … Recommended study design: an observational study of patients with varying patient risk profiles. 7 … Artery Disease, NCT01368770, RCT of 500 patients.

412. Anxiety in Children | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/anxiety-children/research-protocol
     June 01, 2021 - There is a great deal of uncertainty regarding comparative effectiveness and safety of all treatments … that are widely available and validated; which are:(patients/parent reported and clinician assessed), … What are the treatment burdens (for patients, providers, and health systems) and contextual factors ( … KQ 2: Safety outcomes: Pediatric Adverse Event Rating Scale and other scales, incidence of any … Evidence-Based Treatments for Children and Adolescents: An Updated Review of Indicators of Efficacy and

413. Comparative Effectiveness of Angiotensin Converting Enzyme Inhibitors (ACEIs), Angiotensin II Receptor Antagonists (ARBs), and Direct Renin Inhibitors for Treating Essential Hypertension – An Update of the 2007 Report | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/ace-inhibitor-arb-update/research-protocol
     December 01, 2019 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … differ in safety, adverse events, tolerability, persistence, and adherence? … Specific patient subgroups evaluated will be stratified by sex, comorbidities, concurrent medication … demographics and data needed for determining outcomes (intermediate outcomes, health outcomes, and safety … The safety outcomes will be framed to help identify angioedema and hyperkalemia, which are both adverse

414. Microsoft Word - finbody.doc (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/renal-artery-stenosis_research-2007.pdf
     January 01, 2007 - attention on the strength and limits of evidence from research studies about the effectiveness and safety … Analytic framework for evaluating the effectiveness and safety of treatments for renal artery stenosis … A variety of indicators of the severity of ARAS and of health problems, such as poorer kidney function … The reviewed studies did not report any indicators that may predict improved outcomes. … The reviewed studies did not report any indicators that may predict improved outcomes.

415. Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/antiplatelet-treatment/research-protocol
     December 01, 2019 - whether a patient will have a bad outcome on standard clopidogrel therapy? … Which test (or combination of tests or no test) provides the best guide for whether a patient should … and over multiple measurements on the same patient), with some patients showing no platelet response … Efficacy and safety of clopidogrel pretreatment before percutaneous coronary intervention with and without … Meta-analysis of the efficacy and safety of clopidogrel plus aspirin as compared to antiplatelet monotherapy

416. Executive Summary - Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2023 Update (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-executive-summary-2023-update.pdf
     January 01, 2023 - In patients with chronic (mainly neuropathic) pain with short-term treatment (4 weeks to <6 months): … prescribed cannabis (1) Whole-plant cannabis, “certified 12.5% THC” (CBD NR) route determined by patient … final mean dose 16.6/15.4 mg THC/CBD/day vs. 17.2 mg THC/day None specified; based on individual patient … a Patients could choose any medicinal product they preferred in these studies. … Effectiveness, Safety, and Tolerability of Nabiximols Oromucosal Spray vs Typical Oral Long-Acting

417. The Incident User Design in Comparative Effectiveness Research | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/incident-user-design/research
     August 01, 2019 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … Pharmacoepidemiol Drug Safety 2007;16:329-36. 4. Ray WA. … Pharmacoepidemiol Drug Safety 2006;15:81-92. 15. UKPDS Group. … Pharmacoepidemiol Drug Safety 2004;13:695-702. 19. Hippisley-Cox J, Coupland C. … Registries for Evaluating Patient Outcomes: A User’s Guide. AHRQ Publication No. 07-EHC001-1.

418. Topic Coming Back CER 28 DMARDs in Children with JIA NSD _SJ Clean (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_overview.pdf
     March 27, 2014 - How do the efficacy, effectiveness, safety, and adverse effects of treatment with DMARDs differ among … Antirheumatic Drugs (DMARDs) in Children with Juvenile Idiopathic Arthritis (JIA) indicated there were new safety … activity: Active joint count (AJC) Physician global assessment of disease activity (PGA) Parent/patient

419. Evidence Summary: CER 231 Care Interventions for People Living With Dementia and Their Caregivers (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-231-dementia-interventions-evidence-summary_0.pdf
     August 01, 2020 - adaptations of the ACCESS model) may improve system-level markers, including guideline-based quality indicators … Consolidated Standards of Reporting Trials 4 statement), pre-registration of trials, data safety … [Summary for patients in Ann Intern Med. 2006 Nov 21;145(10):I39; PMID: 17116914]. … [Summary for patients in Ann Intern Med. 2006 Nov 21;145(10):I31; PMID: 17116913]. … Effectiveness and Safety of Dementia Care Management in Primary Care: A Randomized Clinical Trial.

420. Treatment of Hepatitis C Virus Infection in Adults: Future Research Needs (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-future_research.pdf
     April 01, 2013 - Do these harms differ according to patient subgroup characteristics, including but not limited to HCV … Do these harms differ according to patient subgroup characteristics, including but not limited to HCV … Do these harms differ according to patient subgroup characteristics? … treated with pegylated interferons in Georgia Long-term SVR according to patient characteristics … , Efficacy and Pharmacokinetics of BI 201335 NA in Patient With Genotype 1 Chronic Hepatitis C