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  1. S143 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/s143.pdf
    October 01, 2007 - Chief among them is the indication for the drug—a patient must have the condition for which the drug … In addition, a collection of less explicit character- istics of both the patient and prescriber influence … the choice of a particular drug for a particular patient at a particular time. … complete (it in- cludes all variables that actually went into the prescribing From the *Ingenix i3 Drug Safety … Seeger, PharmD, DrPH, Ingenix i3 Drug Safety, 950 Winter Street, Suite 3800, Waltham, MA 02451.
  2. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
    May 19, 2010 - Effectiveness of Off-label Use of Atypical Antipsychotics reviewed the scientific evidence on the safety … risk of death and antipsychotics drugs, and comparison of the development of adverse effects between patients … Studies that did not report any outcomes of efficacy, effectiveness, safety/adverse events, or utilization … We will define loss to follow-up as the number of patients excluded from efficacy analyses, expressed … as a proportion of the number of patients randomized.
  3. effectivehealthcare-admin.ahrq.gov/sites/default/files/dementia_horizon-scan-high_impact-1306-revised.pdf
    July 09, 2013 - On the other hand, some thought that knowing that a patient has AD could aid planning for patients … in terms of patient safety and care … safety and care. … They thought that the drug’s well-known safety profile and long history of use (in diabetes) would … AD patients.
  4. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mental-health-mobile-apps-disposition-of-comments.pdf
    May 20, 2022 - There is also no informed consent process to ensure that the client on the other end of the application … This isn't just in Remote patient monitoring apps. … This can ultimately lead to harm of the patient. … vs. harm to patients. … of application to the patient, the safety for phi privacy and safety away from hacking, there is nothing
  5. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
    January 31, 2013 - with aortoiliac disease, supervised exercise therapy improved peak walking time and patient-reported … Patient characteristics such as advanced age, concomitant coronary artery disease or heart failure, … including patient characteristics, severity of symptoms, anatomic considerations, and patient and physician … with CLI.38 Amputation-free survival is generally considered the best limb and patient outcome for … for determining outcomes (intermediate outcomes, health outcomes, and safety outcomes).
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/copd-management_research.pdf
    December 01, 2009 - about the outcomes, clinical effectiveness, safety, and appropriateness of health care items and services … This finding is consistent with other studies on the safety of ipratropium and suggests the need for … additional research on anticholinergic safety.38-40 This finding was also consistent with a study … Future studies that capture medication use patterns, measures of lung function, and patient-reported … The multiple propensity score for analysis of dose-response relationships in drug safety studies.
  7. effectivehealthcare-admin.ahrq.gov/sites/default/files/decide16final-mortality-risk-in-copd-pts-using-theophylline.pdf
    December 01, 2009 - about the outcomes, clinical effectiveness, safety, and appropriateness of health care items and services … This finding is consistent with other studies on the safety of ipratropium and suggests the need for … additional research on anticholinergic safety.38-40 This finding was also consistent with a study … Future studies that capture medication use patterns, measures of lung function, and patient-reported … The multiple propensity score for analysis of dose-response relationships in drug safety studies.
  8. effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/the-roles-of-the-psychiatric-hospital-lengths-of-stay-and-transition-support-services-after-discharge
    November 01, 2017 - addressed, whether the individual and involved family felt that the stay was sufficient to address safety … Compare the effectiveness of diverse models of What patients or group(s) of patients does your … Patients with Serious Mental Illness (SMI) Are there subgroups of patients that your question might … and future safety. … yes If yes, please explain: Managed care has confined hospital stays to acute crisis and safety
  9. effectivehealthcare-admin.ahrq.gov/products/cad-women-diagnosis-future/research
    December 01, 2019 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … traditionally been defined and identified by coronary angiography, a procedure that is indicated in patients … For intermediate-risk patients, clinicians have a wide range of noninvasive technologies (NITs) to choose … The comparative safety and accuracy of these NITs in women was uncertain, although substantial data exists … radiation dose and attributable risk of cancer incidence in women compared with men; however, radiation safety
  10. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rural-telehealth-amended-protocol.pdf
    February 25, 2021 - • Population(s): o Rural individual patients, patient families/care partners, and patient populations … behavior, and decisions such as choice of treatment or antibiotic stewardship; Access measure and indicators … including but not limited to time to diagnosis or time to treatment o KQ2: Indicators and measures … KQ2: a) Indicators and measures of uptake of telehealth (e.g., rates of use, timing to implementation … The Rural Health Safety Net Under Pressure: Rural Hospital Vulnerability. 2020.
  11. effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-244-safety-of-vaccines.pdf
    May 25, 2021 - The level of certainty is not there to support strength of association based on SoE for the patient … Neonatal Nurses (AWHONN) Discussion We would suggest addressing including the process of how patient … and for those whose patients are demonstrating vaccine hesitancy. … The handout should provide relevant links for clinician use and for patient use— maybe two handouts … and a forecast for immunizations due for use by a vaccination provider in determining appropriate client
  12. effectivehealthcare-admin.ahrq.gov/products/treatment-resistant-depression/research-protocol
    March 01, 2020 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … when the patient is treatment resistant. … For adults with treatment-resistant depression, do non-pharmacologic interventions differ in safety, … KQ4 focuses on safety issues (adverse effects, adherence) with each of the interventions. … While the patient is ultimately the one to make the decision about whether to receive the non-pharmacologic
  13. effectivehealthcare-admin.ahrq.gov/products/rural-telehealth/protocol
    January 01, 2023 - Population(s): Rural individual patients, patient families/care partners, and patient populations … , behavior, and decisions such as choice of treatment or antibiotic stewardship; Access measure and indicators … including but not limited to time to diagnosis or time to treatment KQ2: Indicators and measures … KQ2: Indicators and measures of uptake of telehealth (e.g., rates of use, timing to implementation … The Rural Health Safety Net Under Pressure: Rural Hospital Vulnerability . 2020.
  14. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_disposition-comments.pdf
    January 01, 2014 - Peer Reviewer 2 Methods The authors should consistently report separately efficacy and safety. … This section should be renamed “impact of clopidogrel loading on efficacy and safety of bivalirudin … Unfortunately, we do not have individual patient-level data available for analysis. … prospective randomized PLATelet inhibition and patient Outcomes (PLATO) trial. … PLATelet inhibition and patient Outcomes (PLATO) trial.
  15. Obesity (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/obesity_hi_impact.pdf
    April 17, 2012 - data and postmarket safety evaluation, set forth by the U.S. … FDA expressed concerns about the long-term cardiovascular safety profile in the overweight and obese … Experts also opined that further studies evaluating efficacy and safety are needed. … quality of life, thus impacting patient health outcomes. … Safety and efficacy study of EndoBarrier in subjects with type II diabetes and obesity.
  16. effectivehealthcare-admin.ahrq.gov/sites/default/files/04_dementia_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - patient safety and care … safety and care. … A diagnosis could, however, help patients and families plan for the patient’s care and safety. … Furthermore, experts thought that the drug’s well-known safety profile and long history of use (in … AD patients.
  17. effectivehealthcare-admin.ahrq.gov/products/preoperative-testing/research-protocol
    December 01, 2019 - prior to any operative procedure under the assumption that a larger amount of information would enhance safety … complications than patients with normal ECG results. … than patients who did not. … quality of life Patient satisfaction Patient resources, including time and lost work Unplanned … Effective strategy to guide pathology test ordering in surgical patients.
  18. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/insulin-analogues-disposition-081229.pdf
    September 01, 2008 - Comparative Effectiveness, Safety, and Indications of Insulin Analogues in Premixed Formulations for  … Comparative  Effectiveness, Safety, and Indicuations of Insulin Analogues in Premixed Formulations for … information redacted] is pleased to submit comments on the Draft Report on Comparative Effectiveness, Safety … thank the AHRQ for the opportunity to comment on the draft report entitled Comparative Effectiveness, Safety … 6) Page 5 and in the Executive Summary consider adding item f to key question 1: Effectiveness and safety
  19. effectivehealthcare-admin.ahrq.gov/products/n-1-trials/research-2014-2
    August 01, 2019 - With growing concern about the overall safety and risk-benefit profile of many medications, n-of-1 trials … The Patient-Centered Outcomes Research Institute 20 is developing Patient Powered Research Networks … Plan for variable per-patient or per-trial costs Variable costs include recruiting patients, managing … Drug safety on trial. … year's withdrawal of the anti-arthritis drug Vioxx triggered a debate about how to better monitor drug safety
  20. effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/for-adult-patients-with-bipolar-disorder-including-bipolar-i-and-bipolar-ii-disorder-what-is-the-comparative-effectiveness-of-available-treatments-including-psychotherapy-other-psychosocial-treatments-medications-and-other-s
    November 01, 2017 - What are the safety risks and adverse effects of available treatments for bipolar disorder, compared … Yes: Patients with inadequate response Patients with co-occurring substance use disorders Patients … (For example, improvements in patient symptoms or problems from treatment or diagnosis.) … Adverse effects and safety risks of treatments for bipolar disorder, including to the fetus of women … Effectiveness is influenced by patient factors including general medical and psychiatric comorbidities

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