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effectivehealthcare-admin.ahrq.gov/sites/default/files/s143.pdf
October 01, 2007 - Chief among them is the indication for the
drug—a patient must have the condition for which the drug … In addition, a collection of less explicit character-
istics of both the patient and prescriber influence … the choice of
a particular drug for a particular patient at a particular time. … complete (it in-
cludes all variables that actually went into the prescribing
From the *Ingenix i3 Drug Safety … Seeger, PharmD, DrPH, Ingenix i3 Drug Safety, 950
Winter Street, Suite 3800, Waltham, MA 02451.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
May 19, 2010 - Effectiveness of
Off-label Use of Atypical Antipsychotics reviewed the scientific evidence on the safety … risk of death
and antipsychotics drugs, and comparison of the development of adverse effects between patients … Studies that did not report any outcomes of efficacy, effectiveness, safety/adverse events, or
utilization … We will define loss to follow-up as the number of patients excluded from
efficacy analyses, expressed … as a proportion of the number of patients randomized.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/dementia_horizon-scan-high_impact-1306-revised.pdf
July 09, 2013 - On the other hand, some thought that knowing that a patient has AD could aid planning for
patients … in terms of patient safety and care … safety and care. … They
thought that the drug’s well-known safety profile and long history of use (in diabetes) would … AD
patients.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mental-health-mobile-apps-disposition-of-comments.pdf
May 20, 2022 - There is also
no informed consent process to ensure that the client on the other end of the
application … This isn't
just in Remote patient monitoring apps. … This can ultimately lead to harm of the patient. … vs. harm to patients. … of
application to the patient, the safety for phi privacy and safety away from hacking,
there is nothing
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
January 31, 2013 - with
aortoiliac disease, supervised exercise therapy improved peak walking time and patient-reported … Patient characteristics such as advanced age, concomitant coronary artery disease or heart
failure, … including patient characteristics, severity of symptoms, anatomic considerations, and
patient and physician … with CLI.38
Amputation-free survival is generally considered the best limb and patient outcome for … for determining outcomes
(intermediate outcomes, health outcomes, and safety outcomes).
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/copd-management_research.pdf
December 01, 2009 - about the outcomes, clinical effectiveness, safety, and appropriateness of health care items and
services … This finding is consistent
with other studies on the safety of ipratropium and suggests the need for … additional research on
anticholinergic safety.38-40 This finding was also consistent with a study … Future studies that capture medication use patterns, measures of
lung function, and patient-reported … The
multiple propensity score for analysis of
dose-response relationships in drug safety
studies.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/decide16final-mortality-risk-in-copd-pts-using-theophylline.pdf
December 01, 2009 - about the outcomes, clinical effectiveness, safety, and appropriateness of health care items and
services … This finding is consistent
with other studies on the safety of ipratropium and suggests the need for … additional research on
anticholinergic safety.38-40 This finding was also consistent with a study … Future studies that capture medication use patterns, measures of
lung function, and patient-reported … The
multiple propensity score for analysis of
dose-response relationships in drug safety
studies.
-
effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/the-roles-of-the-psychiatric-hospital-lengths-of-stay-and-transition-support-services-after-discharge
November 01, 2017 - addressed, whether the individual and involved family felt that the stay was sufficient to address safety … Compare the effectiveness of diverse models of
What patients or group(s) of patients does your … Patients with Serious Mental Illness (SMI)
Are there subgroups of patients that your question might … and future safety. … yes
If yes, please explain:
Managed care has confined hospital stays to acute crisis and safety
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effectivehealthcare-admin.ahrq.gov/products/cad-women-diagnosis-future/research
December 01, 2019 - EHC
The Evidence-based Practice Centers
The Scientific Resource Center
Registry of Patient … traditionally been defined and identified by coronary angiography, a procedure that is indicated in patients … For intermediate-risk patients, clinicians have a wide range of noninvasive technologies (NITs) to choose … The comparative safety and accuracy of these NITs in women was uncertain, although substantial data exists … radiation dose and attributable risk of cancer incidence in women compared with men; however, radiation safety
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rural-telehealth-amended-protocol.pdf
February 25, 2021 - • Population(s):
o Rural individual patients, patient families/care partners, and patient populations … behavior, and decisions such as choice of treatment
or antibiotic stewardship; Access measure and indicators … including but not limited to
time to diagnosis or time to treatment
o KQ2: Indicators and measures … KQ2:
a) Indicators and measures of uptake of telehealth
(e.g., rates of use, timing to implementation … The Rural Health Safety Net Under Pressure: Rural Hospital
Vulnerability. 2020.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-244-safety-of-vaccines.pdf
May 25, 2021 - The level of
certainty is not there to support
strength of association based on SoE
for the patient … Neonatal
Nurses
(AWHONN)
Discussion We would suggest addressing
including the process of how
patient … and for those whose patients
are demonstrating vaccine hesitancy. … The
handout should provide relevant links
for clinician use and for patient use—
maybe two handouts … and a forecast for immunizations due
for use by a vaccination provider in
determining appropriate client
-
effectivehealthcare-admin.ahrq.gov/products/treatment-resistant-depression/research-protocol
March 01, 2020 - EHC
The Evidence-based Practice Centers
The Scientific Resource Center
Registry of Patient … when the patient is treatment resistant. … For adults with treatment-resistant depression, do non-pharmacologic interventions differ in safety, … KQ4 focuses on safety issues (adverse effects, adherence) with each of the interventions. … While the patient is ultimately the one to make the decision about whether to receive the non-pharmacologic
-
effectivehealthcare-admin.ahrq.gov/products/rural-telehealth/protocol
January 01, 2023 - Population(s):
Rural individual patients, patient families/care partners, and patient populations … , behavior, and decisions such as choice of treatment or antibiotic stewardship; Access measure and indicators … including but not limited to time to diagnosis or time to treatment
KQ2: Indicators and measures … KQ2:
Indicators and measures of uptake of telehealth (e.g., rates of use, timing to implementation … The Rural Health Safety Net Under Pressure: Rural Hospital Vulnerability . 2020.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_disposition-comments.pdf
January 01, 2014 - Peer Reviewer 2 Methods The authors should consistently report separately efficacy and
safety. … This
section should be renamed “impact of clopidogrel loading on
efficacy and safety of bivalirudin … Unfortunately, we do not have individual patient-level
data available for analysis. … prospective randomized PLATelet inhibition
and patient Outcomes (PLATO) trial. … PLATelet inhibition
and patient Outcomes (PLATO) trial.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/obesity_hi_impact.pdf
April 17, 2012 - data and postmarket safety
evaluation, set forth by the U.S. … FDA expressed concerns about the long-term cardiovascular safety profile in the overweight
and obese … Experts also opined that
further studies evaluating efficacy and safety are needed. … quality of life, thus impacting patient health outcomes. … Safety and efficacy study of
EndoBarrier in subjects with type II diabetes and
obesity.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/04_dementia_potential_high_impact_2012-12-10.pdf
January 01, 2012 - patient safety and care … safety and care. … A diagnosis could, however, help patients and families plan for the patient’s care and safety. … Furthermore, experts thought that the drug’s well-known safety profile
and long history of use (in … AD
patients.
-
effectivehealthcare-admin.ahrq.gov/products/preoperative-testing/research-protocol
December 01, 2019 - prior to any operative procedure under the assumption that a larger amount of information would enhance safety … complications than patients with normal ECG results. … than patients who did not. … quality of life
Patient satisfaction
Patient resources, including time and lost work
Unplanned … Effective strategy to guide pathology test ordering in surgical patients.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/insulin-analogues-disposition-081229.pdf
September 01, 2008 - Comparative Effectiveness, Safety, and Indications of Insulin Analogues in Premixed Formulations for … Comparative
Effectiveness, Safety, and Indicuations of Insulin Analogues in Premixed Formulations for … information redacted] is pleased to submit comments on the Draft Report on Comparative
Effectiveness, Safety … thank the AHRQ for the opportunity to comment on the draft report entitled Comparative
Effectiveness, Safety … 6) Page 5 and in the Executive Summary consider adding item f to key question 1: Effectiveness and safety
-
effectivehealthcare-admin.ahrq.gov/products/n-1-trials/research-2014-2
August 01, 2019 - With growing concern about the overall safety and risk-benefit profile of many medications, n-of-1 trials … The Patient-Centered Outcomes Research Institute 20 is developing Patient Powered Research Networks … Plan for variable per-patient or per-trial costs
Variable costs include recruiting patients, managing … Drug safety on trial. … year's withdrawal of the anti-arthritis drug Vioxx triggered a debate about how to better monitor drug safety
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effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/for-adult-patients-with-bipolar-disorder-including-bipolar-i-and-bipolar-ii-disorder-what-is-the-comparative-effectiveness-of-available-treatments-including-psychotherapy-other-psychosocial-treatments-medications-and-other-s
November 01, 2017 - What are the safety risks and adverse effects of available treatments for bipolar disorder, compared … Yes:
Patients with inadequate response
Patients with co-occurring substance use disorders
Patients … (For example, improvements in patient symptoms or problems from treatment or diagnosis.) … Adverse effects and safety risks of treatments for bipolar disorder, including to the fetus of women … Effectiveness is influenced by patient factors including general medical and psychiatric comorbidities