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Showing results for "patient safety indicators".
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301. Adjunctive Devices for Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/acs-pci-adjunctive-devices/research
     December 01, 2019 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … The data comparing adjunctive devices with standard PCI (control) are predominantly in patients with … In RCTs conducted in STEMI patients, catheter aspiration devices decreased the risk of a major adverse … Due to insufficient data, the safety of these devices is unclear. … Project Timeline Adjunctive Devices for Patients With Acute Coronary Syndrome Undergoing Percutaneous

302. First and Second Generation Antipsychotics for Children and Young Adults-Comparative Effectiveness Review Update | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/antipsychotics-children-update/research-protocol
     April 01, 2020 - Within each KQ, we will assess outcomes for subgroups of patients or studies based on patient and clinical … Broadened use of atypical antipsychotics: safety, effectiveness, and policy challenges. … Efficacy and safety of second-generation antipsychotics in children and adolescents with psychotic and … Drug Safety. 2011 Aug 1;34(8):651-68. PMID: 21751826. Correll CU, Penzner JB, Parikh UH, et al. … Limited evidence in children <12 years Use and safety have not been evaluated in other childhood

303. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1512.pdf
     November 01, 2016 - acceptance is likely to be high because of the ease of administration and good safety profile, most … Study to evaluate the long-term safety and efficacy of elagolix in subjects with moderate to severe … A global phase 3 study to evaluate the safety and efficacy of elagolix in subjects with moderate … Global study to evaluate the long-term safety and efficacy of elagolix in subjects with moderate … A clinical study to evaluate the safety and efficacy of elagolix in subjects with moderate to severe

304. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1506.pdf
     November 01, 2016 - acceptance is likely to be high because of the ease of administration and good 4 safety profile … A clinical study to evaluate the safety and efficacy of elagolix in subjects with moderate to severe … Study to evaluate the long-term safety and efficacy of elagolix in subjects with moderate to severe … A global phase 3 study to evaluate the safety and efficacy of elagolix in subjects with moderate … Global study to evaluate the long-term safety and efficacy of elagolix in subjects with moderate

305. FRN 35 - Preventive Pharmacological Treatments for Migraine in Adults: Future Research Needs (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
     April 01, 2013 - KQ 3: Which patient characteristics predict the effectiveness and safety of pharmacologic treatments … by selected patient characteristics: • Onabotulinumtoxin A was more effective in patients with a … 2 Key Question 3 Which patient characteristics predict the effectiveness and safety of pharmacologic … KQ 3: Which patient characteristics predict the effectiveness and safety of pharmacologic treatments … Designed to Test the Effectiveness and Safety of Treating Patients With Lacosamide for Migraine Prophylaxis

306. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/arthritis_hi_impact.pdf
     January 01, 2014 - IL-1 may be a problematic target with respect to safety in the gout patient population, however, and … and tolerability due to safety concerns over infections reported in trials thus far. … These safety concerns may present barriers to approval or barriers to diffusion if approved. … These safety concerns may present significant barriers to approval and diffusion if approved. … SLE: belimumab safety, efficacy sustained over 6 years. [internet].

307. Disposition of Comments for Migraine in Adults: Preventive Pharmacologic Treatments (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/migraine-prevention_disposition-comments.pdf
     April 18, 2013 - safety but no efficacy report. to what purpose? … A large scale, longitudinal study of specific subgroups of migraineurs including quality of life indicators … designed, including longitudinal study of specific subgroups of migraineurs including quality of life indicators … Data from a pooled safety analysis of topiramate showed that out of 1,135 patients who received topiramate … Analysis of safety and tolerability data obtained from over 1,500 patients receiving topiramate for

308. Prehospital EMS Blood Transfusion and Fluid Interventions for Hemorrhagic Shock (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol-amendment.pdf
     February 04, 2025 - Which component combinations result in the best patient outcomes for which types of patients? … free days o ICU free days Intermediate Outcomes in the prehospital or ED setting • Physiological indicators … hemorrhagic shock characteristics (e.g., mechanism of injury/condition, severity, blood pressure, other indicators … = Mixed Methods Appraisal Tool; NA = not applicable; NHTSA = National Highway and Transportation Safety … Role of the Funder This project was funded by the National Highway and Transportation Safety Administration

309. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
     January 01, 2007 - All the same issues noted for RA of short- and long-term risks and safety, as well as performance in … to reduce patient-reported symptoms, to slow or limit progression of radiographic joint damage, or … and observational studies is insufficient to draw conclusions about the comparative tolerability and safety … Safety and efficacy of adalimumab in treatment of patients with psoriatic arthritis who had failed disease … : patient-reported outcomes of the Adalimumab Effectiveness in Psoriatic Arthritis Trial.

310. Acute Migraine Treatment in Emergency Settings | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/migraine-emergency/research-protocol
     December 01, 2019 - Question 5 Does the effectiveness and safety of the parenteral pharmacological interventions vary in … Safety: RCTs, NRCTs, and prospective cohort studies. … Exclusion of patients with comorbidities. … Dodick D, Lipton RB, Martin V, et al, for the Triptan Cardiovascular Safety Expert Panel. … Consensus statement: cardiovascular safety profile of triptans (5-HT agonists) in the acute treatment

311. Nephropathy-Contrast-Induced Executive-2016 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive-2016.pdf
     January 01, 2016 - How do benefits or harms of contrast media differ by patient characteristics (known risk factors such … definitive evidence of a difference in CIN incidence between IOCM and LOCM that varied according to patient … A prospective, double-blind, randomized, controlled trial on the efficacy and cardiorenal safety of … The relative renal safety of iodixanol compared with low-osmolar contrast media: a meta- analysis of … Effect of administration route on the renal safety of contrast agents: a meta-analysis of randomized

312. Microsoft Word - Comp Eff 10.doc (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-2007_research-2007-1.pdf
     January 01, 2007 - For adult patients with essential hypertension, how do ACEIs and ARBs differ in safety, adverse events … For adult patients with essential hypertension, how do ACEIs and ARBs differ in safety,d adverse events … For adult patients with essential hypertension, how do ACEIs and ARBs differ in safety, adverse events … For adult patients with essential hypertension, how do ACEIs and ARBs differ in safety,d adverse events … Many of the studies reported limited data on patient characteristics, and black patients appeared to

313. Diagnostic Errors in the Emergency Department: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/diagnostic-errors-emergency-updated/research
     August 01, 2023 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … Diagnostic errors are a known patient safety concern across all clinical settings, including the emergency … to facilitate the rapid development and deployment of solutions to address this critically important patient … safety concern. … Meta-analysis White Paper May 31, 2024 Making Healthcare Safer IV: Summary of Findings on Patient

314. Comparative Effectiveness of First and Second Generation Antipsychotics in the Adult Population | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/antipsychotics-adults/research-protocol
     December 01, 2019 - Patient insight into illness. Health-related quality of life. Patient satisfaction. … Patient insight into illness. Health-related quality of life. … Patient satisfaction. Patient-reported outcomes. … Haloperidol Approved 1986 Schizophrenia Tourette’s Disorder Adults Safety and … Adults Pediatric use: safety & effectiveness not established in patients <18 yrs 1. agranulocytosis

315. Improving Antibiotic Prescribing for Uncomplicated Acute Respiratory Tract Infections | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/antibiotics-respiratory-infection/research
     December 01, 2019 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … of antibiotics for acute RTIs and not causing adverse consequences such as medical complications or patient … Conclusions The best evidence supports the use of specific education interventions for patients/parents … Safety Practices and Ratings by a Technical Expert Panel, 2023-2024 Rapid Evidence Product … Safety Practices for a New Rapid Review or Rapid Response Page last

316. Comparative Effectiveness of Pain Management Interventions for Hip Fracture | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/hip-fracture-pain/research-protocol
     December 01, 2019 - It may be patient defined or proxy reported. … For the questions on safety and adverse effects, in addition to the above databases, we will search the … Does functional recovery in elderly hip fracture patients differ between patients admitted from long-term … Pain management after total joint replacement and its impact on patient outcomes. … Evidence for safety of pharmacologic and nonpharmacologic pain management interventions K3: In

317. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_research-protocol.pdf
     December 09, 2009 - It may be patient defined or proxy reported. … For the questions on safety and adverse effects, in addition to the above databases, we will search … Does functional recovery in elderly hip fracture patients differ between patients admitted from long-term … Pain management after total joint replacement and its impact on patient outcomes. … Evidence for safety of pharmacologic and nonpharmacologic pain management interventions K3:

318. Disposition of Comments Technical Brief 41: Evaluation of Mental Health Mobile Applications (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mental-health-mobile-apps-disposition-of-comments.pdf
     May 20, 2022 - There is also no informed consent process to ensure that the client on the other end of the application … This isn't just in Remote patient monitoring apps. … This can ultimately lead to harm of the patient. … vs. harm to patients. … of application to the patient, the safety for phi privacy and safety away from hacking, there is nothing

319. Peripheral-Artery-Disease-Treatment Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
     January 31, 2013 - with aortoiliac disease, supervised exercise therapy improved peak walking time and patient-reported … Patient characteristics such as advanced age, concomitant coronary artery disease or heart failure, … including patient characteristics, severity of symptoms, anatomic considerations, and patient and physician … with CLI.38 Amputation-free survival is generally considered the best limb and patient outcome for … for determining outcomes (intermediate outcomes, health outcomes, and safety outcomes).

320. Disposition of Comments Report for Chronic Venous Ulcers: A Comparative Effectiveness Review of Treatment Modalities (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_disposition-comments.pdf
     January 27, 2014 - The patient perspective is important to the EPC program, and we tried very hard to recruit patients … A wound care organization recommended this particular patient to us because the patient has had chronic … of 188 patients. … The data demonstrated safety and efficacy in healing patients with VLUs in ulcers greater than 1 … As stated previously, the Apligraf pivotal study was only designed to test safety and efficacy in