-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_surveillance.pdf
June 01, 2012 - the
majority of conclusions for KQ1-KQ2 were not still valid
• No FDA, Health Canada, and MHRA safety … magnitude/direction of
changes in estimates, potential changes in practice or therapy preference, safety … evidence does
not support statements on whether
other clinical features (such as
demographics or indicators … NR;
(n=76)
Two years Primary:
20% or
greater
decrease in
creatinine
clearance;
Secondary:
safety … evidence does not support statements on
whether other clinical features (such as demographics or
indicators
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effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/the-roles-of-the-psychiatric-hospital-lengths-of-stay-and-transition-support-services-after-discharge
November 01, 2017 - addressed, whether the individual and involved family felt that the stay was sufficient to address safety … Compare the effectiveness of diverse models of
What patients or group(s) of patients does your … Patients with Serious Mental Illness (SMI)
Are there subgroups of patients that your question might … and future safety. … yes
If yes, please explain:
Managed care has confined hospital stays to acute crisis and safety
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effectivehealthcare-admin.ahrq.gov/products/acs-pci-adjunctive-devices/research
December 01, 2019 - EHC
The Evidence-based Practice Centers
The Scientific Resource Center
Registry of Patient … The data comparing adjunctive devices with standard PCI (control) are predominantly in patients with … In RCTs conducted in STEMI patients, catheter aspiration devices decreased the risk of a major adverse … Due to insufficient data, the safety of these devices is unclear. … Project Timeline
Adjunctive Devices for Patients With Acute Coronary Syndrome Undergoing Percutaneous
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/musculoskeletal-disorders-imaging_disposition-comments.pdf
November 01, 2011 - Safety: The ramfiicaitons regarding potential need for alternative
imaging methods (pg 16, lines 10- … 13) to rule out specific pathologies
is to some extent a safety issue (e.g. ? … safety/outcomes. … vs. an adverse event related to the
safety of the device or procedure? … frequency of
positive MRI exams on clinically asymptomatic
patients.
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effectivehealthcare-admin.ahrq.gov/products/antibiotics-respiratory-infection/research
December 01, 2019 - EHC
The Evidence-based Practice Centers
The Scientific Resource Center
Registry of Patient … of antibiotics for acute RTIs and not causing adverse consequences such as medical complications or patient … Conclusions
The best evidence supports the use of specific education interventions for patients/parents … Safety Practices and Ratings by a Technical Expert Panel, 2023-2024
Rapid Evidence Product … Safety Practices for a New Rapid Review or Rapid Response
Page last
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
January 01, 2007 - All the
same issues noted for RA of short- and long-term risks
and safety, as well as performance in … to reduce patient-reported
symptoms, to slow or limit progression of
radiographic joint damage, or … and
observational studies is insufficient to draw conclusions
about the comparative tolerability and safety … Safety and efficacy of
adalimumab in treatment of patients with psoriatic
arthritis who had failed disease … : patient-reported outcomes of the
Adalimumab Effectiveness in Psoriatic Arthritis Trial.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol.pdf
September 24, 2024 - Which component combinations result in the best patient outcomes
for which types of patients? … free days
o ICU free days
Intermediate Outcomes in the prehospital or ED setting
• Physiological indicators … hemorrhagic shock characteristics (e.g., mechanism of
injury/condition, severity, blood pressure, other indicators … = Mixed Methods Appraisal Tool;
NA = not applicable; NHTSA = National Highway and Transportation Safety … Role of the Funder
This project was funded by the National Highway and Transportation Safety Administration
-
effectivehealthcare-admin.ahrq.gov/products/antipsychotics-adults/research-protocol
December 01, 2019 - Patient insight into illness.
Health-related quality of life.
Patient satisfaction. … Patient insight into illness.
Health-related quality of life. … Patient satisfaction.
Patient-reported outcomes. … Haloperidol
Approved 1986
Schizophrenia
Tourette’s Disorder
Adults
Safety and … Adults
Pediatric use: safety & effectiveness not established in patients <18 yrs
1. agranulocytosis
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-2007_research-2007-1.pdf
January 01, 2007 - For adult patients with essential hypertension, how do ACEIs
and ARBs differ in safety, adverse events … For adult patients with essential hypertension, how do ACEIs and ARBs differ
in safety,d adverse events … For adult patients
with essential hypertension, how do
ACEIs and ARBs differ in safety,
adverse events … For adult patients with essential hypertension, how do ACEIs and ARBs differ
in safety,d adverse events … Many of the studies
reported limited data on patient characteristics, and black patients appeared to
-
effectivehealthcare-admin.ahrq.gov/products/phenylketonuria/research-protocol
December 01, 2019 - EHC
The Evidence-based Practice Centers
The Scientific Resource Center
Registry of Patient … of the long-term use of LNAAs and about the target patient population, including the appropriateness … , the safety and efficacy of using sapropterin dihydrochloride in children under the age of 8, including … long-term effects of pharmacological treatment or the desired Phe concentration ranges for various patient … Primary outcomes in a patient:
Decreasing Phe levels in the blood
Improved nutritional status
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
January 31, 2013 - with
aortoiliac disease, supervised exercise therapy improved peak walking time and patient-reported … Patient characteristics such as advanced age, concomitant coronary artery disease or heart
failure, … including patient characteristics, severity of symptoms, anatomic considerations, and
patient and physician … with CLI.38
Amputation-free survival is generally considered the best limb and patient outcome for … for determining outcomes
(intermediate outcomes, health outcomes, and safety outcomes).
-
effectivehealthcare-admin.ahrq.gov/products/antipsychotics-children-update/research-protocol
April 01, 2020 - Within each KQ, we will assess outcomes for subgroups of patients or studies based on patient and clinical … Broadened use of atypical antipsychotics: safety, effectiveness, and policy challenges. … Efficacy and safety of second-generation antipsychotics in children and adolescents with psychotic and … Drug Safety. 2011 Aug 1;34(8):651-68. PMID: 21751826.
Correll CU, Penzner JB, Parikh UH, et al. … Limited evidence in children <12 years
Use and safety have not been evaluated in other childhood
-
effectivehealthcare-admin.ahrq.gov/products/migraine-emergency/research-protocol
December 01, 2019 - Question 5
Does the effectiveness and safety of the parenteral pharmacological interventions vary in … Safety: RCTs, NRCTs, and prospective cohort studies. … Exclusion of patients with comorbidities. … Dodick D, Lipton RB, Martin V, et al, for the Triptan Cardiovascular Safety Expert Panel. … Consensus statement: cardiovascular safety profile of triptans (5-HT agonists) in the acute treatment
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_research-protocol.pdf
December 09, 2009 - It may be patient defined or proxy reported. … For the questions on safety and adverse effects, in addition to the above databases, we
will search … Does functional recovery in elderly hip
fracture patients differ between patients admitted from long-term … Pain management after total joint replacement and its impact on
patient outcomes. … Evidence for
safety of
pharmacologic and
nonpharmacologic
pain management
interventions
K3:
-
effectivehealthcare-admin.ahrq.gov/products/hip-fracture-pain/research-protocol
December 01, 2019 - It may be patient defined or proxy reported. … For the questions on safety and adverse effects, in addition to the above databases, we will search the … Does functional recovery in elderly hip fracture patients differ between patients admitted from long-term … Pain management after total joint replacement and its impact on patient outcomes. … Evidence for safety of pharmacologic and nonpharmacologic pain management interventions
K3: In
-
effectivehealthcare-admin.ahrq.gov/products/atypical-antipsychotics-off-label-update/research-protocol
March 01, 2020 - EHC
The Evidence-based Practice Centers
The Scientific Resource Center
Registry of Patient … Comparative Effectiveness of Off-label Use of Atypical Antipsychotics reviewed the scientific evidence on the safety … Studies that did not report any outcomes of efficacy, effectiveness, safety/adverse events, or utilization … We will define loss to follow-up as the number of patients excluded from efficacy analyses, expressed … as a proportion of the number of patients randomized.
-
effectivehealthcare-admin.ahrq.gov/products/cad-women-diagnosis-future/research
December 01, 2019 - EHC
The Evidence-based Practice Centers
The Scientific Resource Center
Registry of Patient … traditionally been defined and identified by coronary angiography, a procedure that is indicated in patients … For intermediate-risk patients, clinicians have a wide range of noninvasive technologies (NITs) to choose … The comparative safety and accuracy of these NITs in women was uncertain, although substantial data exists … radiation dose and attributable risk of cancer incidence in women compared with men; however, radiation safety
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/migraine_protocol-appendix_20111103.pdf
November 03, 2011 - exp patient care team/
3. exp delivery of health care, integrated/
4. integrated care.mp.
5. … exp Patient Education as Topic/
8. exp Health Education/
9. … surveillance.mp.
10. exp drug monitoring/
11. 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 or 9 or 10
12. exp patient … continued)
Source: www.effectivehealthcare.ahrq.gov
Published Online: November 3, 2011
A-8
13. exp patient … satisfaction/
14. exp patient care management/
15. 12 or 13 or 14
16. exp migraine disorders/dt
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/dementia_horizon-scan-high_impact-1306-revised.pdf
July 09, 2013 - On the other hand, some thought that knowing that a patient has AD could aid planning for
patients … in terms of patient safety and care … safety and care. … They
thought that the drug’s well-known safety profile and long history of use (in diabetes) would … AD
patients.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1512.pdf
December 01, 2015 - Many of newly added topics
use this integrated approach, and we look forward to the generation of safety … options, experts expressed concerns about the drug’s safety profile and
best administration method … Although intravenous ketamine has
known safety risks and might require increased infrastructure or … Optimism for this
intervention’s potential was tempered by available efficacy and safety data; several … Several experts were concerned about ketamine’s adverse event profile and noted that
safety risks could