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281. Carbohydrates | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/carbohydrates?page=1
     May 29, 2013 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … Mellitus Research Protocol Archived June 2, 2011 Comparative Effectiveness and Safety … Abstract Archived December 15, 2009 Anticoagulation for Venous Thromboembolic Events in Patients … Diabetes Systematic Review Archived September 15, 2008 Comparative Effectiveness, Safety … Diabetes Systematic Review Archived July 16, 2007 Comparative Effectiveness and Safety

282. #05 DEPRESSION (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1312.pdf
     October 01, 2014 - DBS to the subcallosal cingulate white matter supported the long-term safety and antidepressant efficacy … The safety of ECT in patients with an implanted DBS system has not been established. … ketamine would have a minimal impact on health outcomes in the absence of data on long-term effects, safety … Efficacy and safety of mifepristone for the treatment of psychotic depression. … Neuropsychological safety of nucleus accumbens deep brain stimulation for major depression: effects

283. Project Title: Evaluation of Suspicious Skin Lesions Using Non-Invasive Diagnostic Techniques, a Technical Brief (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/skin-lesions-evaluation_research-protocol.pdf
     August 23, 2010 - What are the potential safety issues and harms associated with the use of non-invasive diagnostic techniques … Guiding question 3: What published and unpublished studies have reported on the use and safety of these … Provide a synthesis of the following information: i Indication/patient inclusion criteria ii Type … of techniques/modalities iii Study design and size iv Role of the test in patient management v … Strategies for early melanoma detection: Approaches to the patient with nevi.

284. Since their introduction in 20xx, DES have been shown in clinical trials to decrease TLR (… (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/coronary-stents-outcomes_research.pdf
     January 01, 2010 - about the outcomes, clinical effectiveness, safety, and appropriateness of health care items and services … Effectiveness and Safety of Drug- Eluting Stents in Ontario. … Balancing Efficacy and Safety of Drug-Eluting Stents in Patients Undergoing Percutaneous Coronary … Safety and Efficacy of Sirolimus- and Paclitaxel-Eluting Coronary Stents. … Unadjusted baseline characteristics of patients in study population Patient Characteristics Study

285. Untitled (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antipsychotics-children-update_research-protocol.pdf
     December 04, 2015 - Within each KQ, we will assess outcomes for subgroups of patients or studies based on patient and clinical … (patientsafety, effectiveness, and policy challenges. … Efficacy and safety of second-generation antipsychotics in children and adolescents with psychotic and … Drug Safety. 2011 Aug 1;34(8):651-68. PMID: 21751826. 17.

286. Obesity (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
     January 01, 2012 - significantly increased the regulatory bar for gaining approval—specifically regarding preapproval safety … data and postmarket safety evaluation—set forth by the U.S. … Kushner and colleagues announced results from a phase III clinical trial (SEQUEL) evaluating the safety … However, potential increase in per- patient costs might serve as barriers to acceptance by some patients … Safety and efficacy study of EndoBarrier in subjects with type II diabetes and obesity.

287. FRN 35 - Preventive Pharmacological Treatments for Migraine in Adults: Future Research Needs (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
     April 01, 2013 - KQ 3: Which patient characteristics predict the effectiveness and safety of pharmacologic treatments … by selected patient characteristics: • Onabotulinumtoxin A was more effective in patients with a … 2 Key Question 3 Which patient characteristics predict the effectiveness and safety of pharmacologic … KQ 3: Which patient characteristics predict the effectiveness and safety of pharmacologic treatments … Designed to Test the Effectiveness and Safety of Treating Patients With Lacosamide for Migraine Prophylaxis

288. Microsoft Word - 3-DKE274__ACEI-ARB-DRI__Comments_Disposition_Table-21_Jan_2011 cyk _2_.docx (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_disposition-comments.pdf
     October 07, 2011 - daily, which is achieved by doubling the dose at approximately 2-week intervals, as tolerated by the patient … For Results Key Question 2, safety information, please note that ACE inhibitors pose unique, albeit … congestive heart failure, or nephropathy); however all have examined an overlapping set of efficacy and safety … of “class effects”, specifically related to ACEIs and ARBs, discussing that mechanism of action, safety … We underscore the importance of updating any corollary materials (e.g., patient guides) in order to

289. Making Healthcare Safer IV Rapid Review: Patient Monitoring Systems To Prevent Failure To Rescue (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/patient-monitoring-systems-rapid-review.pdf
     December 01, 2024 - patient safety studies. … Director, General Patient Safety Program Center for Quality Improvement and Patient Safety Agency for … Standard Patient safety/harm search string for all PSPs topics “patient safety”[mh] OR “patient … Standard Patient safety/harm search string for all PSPs topics [mh “patient safety”] OR “patient … patient safety?

290. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1506.pdf
     November 01, 2016 - acceptance is likely to be high because of the ease of administration and good 4 safety profile … A clinical study to evaluate the safety and efficacy of elagolix in subjects with moderate to severe … Study to evaluate the long-term safety and efficacy of elagolix in subjects with moderate to severe … A global phase 3 study to evaluate the safety and efficacy of elagolix in subjects with moderate … Global study to evaluate the long-term safety and efficacy of elagolix in subjects with moderate

291. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1512.pdf
     November 01, 2016 - acceptance is likely to be high because of the ease of administration and good safety profile, most … Study to evaluate the long-term safety and efficacy of elagolix in subjects with moderate to severe … A global phase 3 study to evaluate the safety and efficacy of elagolix in subjects with moderate … Global study to evaluate the long-term safety and efficacy of elagolix in subjects with moderate … A clinical study to evaluate the safety and efficacy of elagolix in subjects with moderate to severe

292. Technical Brief: Evaluation of Suspicious Skin Lesions Using Non-Invasive Diagnostic Techniques | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/skin-lesions-evaluation/research-protocol
     December 01, 2019 - whether or not patients have a history of other malignancies. … What are the potential safety issues and harms associated with the use of non-invasive diagnostic techniques … Guiding question 3: What published and unpublished studies have reported on the use and safety of these … the technique/modality was used Outcomes assessed Adverse events, harms and safety issues reported … Strategies for early melanoma detection: Approaches to the patient with nevi.

293. Diagnostic Errors in the Emergency Department: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/diagnostic-errors-emergency-updated/research
     August 01, 2023 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … Diagnostic errors are a known patient safety concern across all clinical settings, including the emergency … to facilitate the rapid development and deployment of solutions to address this critically important patient … safety concern. … Meta-analysis White Paper May 31, 2024 Making Healthcare Safer IV: Summary of Findings on Patient

294. Disposition of Comments Technical Brief 41: Evaluation of Mental Health Mobile Applications (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mental-health-mobile-apps-disposition-of-comments.pdf
     May 20, 2022 - There is also no informed consent process to ensure that the client on the other end of the application … This isn't just in Remote patient monitoring apps. … This can ultimately lead to harm of the patient. … vs. harm to patients. … of application to the patient, the safety for phi privacy and safety away from hacking, there is nothing

295. Disposition of Comments for Migraine in Adults: Preventive Pharmacologic Treatments (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/migraine-prevention_disposition-comments.pdf
     April 18, 2013 - safety but no efficacy report. to what purpose? … A large scale, longitudinal study of specific subgroups of migraineurs including quality of life indicators … designed, including longitudinal study of specific subgroups of migraineurs including quality of life indicators … Data from a pooled safety analysis of topiramate showed that out of 1,135 patients who received topiramate … Analysis of safety and tolerability data obtained from over 1,500 patients receiving topiramate for

296. Hyperglycemia | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/hyperglycemia
     June 05, 2013 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … Mellitus Research Protocol Archived June 2, 2011 Comparative Effectiveness and Safety … Mellitus Systematic Review Archived September 15, 2008 Comparative Effectiveness, Safety

297. Urinary-Incontinence-Treatment Surveillance (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
     October 29, 2012 - • There are no safety concerns Summary Decision: This CER’s priority for updating is Low … UUI in 40% patients on 150 U; p=0.022 • >75% improvement versus baseline in UUI in 40% patients on 100 … UUI in 40% patients on 150 U; p=0.022 >75% improvement versus baseline in UUI in 40% patients on … The  efficacy  and  safety  of  solifenacin   in  patients  with  overactive  bladder … in 40% patients on 150 U; p=0.022 >75% improvement versus baseline in UUI in 40% patients on 100

298. Disposition of Comments Report for CER 203 ADHD (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-203-adhd-disposition-comments.pdf
     January 01, 2018 - In my assessment, post-marketing surveillance studies of effectiveness and safety are badly missing … These outcomes were seen as being both patient-centered and most critical for decisionmaking across … Effectiveness, safety, and tolerability of lisdexamfetamine dimesylate in children with attention- … A long-term o pen-label safety and effectiveness trial of lisdexamfetamine dimesylate in adolescents … Atomoxetine improves patient and family coping in attention deficit/hyperactivity disorder: a randomized

299. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/arthritis_hi_impact.pdf
     January 01, 2014 - IL-1 may be a problematic target with respect to safety in the gout patient population, however, and … and tolerability due to safety concerns over infections reported in trials thus far. … These safety concerns may present barriers to approval or barriers to diffusion if approved. … These safety concerns may present significant barriers to approval and diffusion if approved. … SLE: belimumab safety, efficacy sustained over 6 years. [internet].

300. Nephropathy-Contrast-Induced Executive-2016 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive-2016.pdf
     January 01, 2016 - How do benefits or harms of contrast media differ by patient characteristics (known risk factors such … definitive evidence of a difference in CIN incidence between IOCM and LOCM that varied according to patient … A prospective, double-blind, randomized, controlled trial on the efficacy and cardiorenal safety of … The relative renal safety of iodixanol compared with low-osmolar contrast media: a meta- analysis of … Effect of administration route on the renal safety of contrast agents: a meta-analysis of randomized