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  1. effectivehealthcare-admin.ahrq.gov/health-topics/dietary-proteins?page=4
    March 09, 2010 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … Agents Systematic Review Archived September 15, 2008 Comparative Effectiveness, Safety … in Adults Systematic Review Archived July 16, 2007 Comparative Effectiveness and Safety … Archived May 23, 2006 Comparative Effectiveness of Epoetin and Darbepoetin for Managing Anemia in Patients … Study to Assess Association of Variations in OCT Genes with Effectiveness of Metformin in Diabetic Patients
  2. effectivehealthcare-admin.ahrq.gov/products/pediatric-ehr/technical-brief
    December 01, 2019 - support the work of child health care providers and assure the delivery of quality care to pediatric patients … medication dosing, pediatric disease management, pediatric norms, and the relationship between pediatric patients … that if these functionalities are implemented well, the EHR will also better support the care of all patients … medical home; (2) a desire to support and maintain patient safety; and (3) the increasing presence of … Safety Practices and Ratings by a Technical Expert Panel, 2023-2024 Technical Brief May
  3. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/lysosomal-storage-diseases-therapies_research-protocol.pdf
    November 15, 2012 - every other week, for the life of the patient. … What are the potential safety issues and harms with ERT? 2. … What published and unpublished studies have reported on the use and safety of this intervention? … Adverse events/harms/safety issues reported 4. … patient and one parent of a child patient will be consulted.
  4. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_executive.pdf
    November 01, 2012 - In patients with chronic plaque psoriasis, what is the comparative safety of systemic biologic agents … To be included, the patient population evaluated in the study must have been adult patients (≥18 years … In an RCT that compared the efficacy and safety of adalimumab with placebo in patients with moderate … Study Evaluating the Efficacy and Safety of Etanercept and Acitretin in Korean Patient With Moderate … Safety and efficacy study on etanercept in patients with plaque psoriasis.
  5. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
    February 01, 2018 - The workgroup suggests that EPC reviews focus on indicators of more severe harms (e.g., “serious” adverse … 9) How should input from technical and clinical experts and patients or patient advocacy groups be used … How should input from technical and clinical experts and patients or patient advocacy groups be used … Had to report data from groups of in which at least 85% of the patients were from one of the patient … What are the harms of therapeutic interventions for patients with ME/CFS and how do they vary by patient
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_executive.pdf
    May 01, 2013 - The burden of VTE is higher among some patient populations, including patients who have experienced … and safety of pharmacologic strategies for VTE prevention in patients with liver disease. … effectiveness and safety of pharmacologic strategies among patients with liver disease. … in the patient populations. … RCTs should evaluate the comparative effectiveness and safety of LMWHs in obese patients.
  7. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-selection-harms-systematic-reviews.pdf
    February 01, 2018 - 2016. http://www.fda.gov/Safety/MedWatch/HowToReport/ucm053087.htm (accessed October 2, 2017) 1. … Eliciting patient perspective in patient-centered outcomes research: a meta narrative systematic review … Eliciting patient perspective in patient-centered outcomes research: a meta narrative systematic review … EPC reviews should focus on indicators of more severe harms as it is more difficult to interpret the … Eliciting patient perspective in patient-centered outcomes research: a meta narrative systematic review
  8. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment-future_research.pdf
    January 01, 2014 - with patient dropouts. … retention Patients Standardized characterization and reporting of patient and wound characteristics … It is also extremely painful to the patient. … Population Standards for Describing Participating Patients and Their Ulcers Reporting of patient characteristics … , patient-reported and other secondary outcomes.
  9. effectivehealthcare-admin.ahrq.gov/health-topics/carbohydrates?page=1
    May 21, 2013 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … Mellitus Research Protocol Archived June 2, 2011 Comparative Effectiveness and Safety … Abstract Archived December 15, 2009 Anticoagulation for Venous Thromboembolic Events in Patients … Diabetes Systematic Review Archived July 16, 2007 Comparative Effectiveness and Safety … 2005 Addressing Knowledge Gaps in Type 2 Diabetes Therapeutics: Comparative Effectiveness and Safety
  10. S131 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/s131.pdf
    October 01, 2007 - Presented at the Agency for Healthcare Research and Quality meeting on “Comparative Effectiveness and Safety … competitors within a class are often marketed for better efficacy, slightly expanded indications, or better safety … Baseline patient characteristics are presented in Table 1. … the effectiveness and safety of a particular drug that I am about to start and continue to use, compared … , we identified a set of restrictions that analysts should consider in epidemiologic studies of the safety
  11. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ems-911-workforce-disposition-comments.pdf
    November 01, 2022 - Background and Purpose, I disagree saying the 911 workers have contact with the public and multiple patients … of the background section to indicate that public-facing EMS clinicians have contact with multiple patients … o acknowledge that exposures may result from activities not involving direct contact with patients … ) evaluation of strategies implemented by 911 call centers that aid in the detection of infectious patients … The Needlestick Safety & Prevention Act of 2000 was passed by the U.S.
  12. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_executive.pdf
    April 01, 2013 - KQ 2: For patients with PAH, what are the comparative effectiveness and safety of (a) echocardiography … KQ 3: For patients with PAH, what are the comparative effectiveness and safety of monotherapy or combination … We found no studies describing the safety (or harms) of echocardiography or biomarker testing. … Twenty-eight RCTs involving 3,613 patients evaluated the comparative effectiveness and safety of monotherapy … The mean patient ages ranged from 28 to 50 years old.
  13. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/treatment-resistant-depression_research-protocol.pdf
    December 09, 2009 - when the patient is treatment resistant. … For adults with treatment-resistant depression, do non-pharmacologic interventions differ in safety, … Comparators: ECT, rTMS, VNS, demonstrated effective psychotherapy • Outcomes for each question • Safety … KQ4 focuses on safety issues (adverse effects, adherence) with each of the interventions. … While the patient is ultimately the one to make the decision about whether to receive the non- pharmacologic
  14. #05 DEPRESSION (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1312.pdf
    October 01, 2014 - DBS to the subcallosal cingulate white matter supported the long-term safety and antidepressant efficacy … The safety of ECT in patients with an implanted DBS system has not been established. … ketamine would have a minimal impact on health outcomes in the absence of data on long-term effects, safety … Efficacy and safety of mifepristone for the treatment of psychotic depression. … Neuropsychological safety of nucleus accumbens deep brain stimulation for major depression: effects
  15. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol.pdf
    September 24, 2024 - Which component combinations result in the best patient outcomes for which types of patients? … free days o ICU free days Intermediate Outcomes in the prehospital or ED setting • Physiological indicators … hemorrhagic shock characteristics (e.g., mechanism of injury/condition, severity, blood pressure, other indicators … = Mixed Methods Appraisal Tool; NA = not applicable; NHTSA = National Highway and Transportation Safety … Role of the Funder This project was funded by the National Highway and Transportation Safety Administration
  16. Untitled (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antipsychotics-children-update_research-protocol.pdf
    December 04, 2015 - Within each KQ, we will assess outcomes for subgroups of patients or studies based on patient and clinical … (patientsafety, effectiveness, and policy challenges. … Efficacy and safety of second-generation antipsychotics in children and adolescents with psychotic and … Drug Safety. 2011 Aug 1;34(8):651-68. PMID: 21751826. 17.
  17. effectivehealthcare-admin.ahrq.gov/health-topics/hypoglycemia
    April 19, 2016 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … Effectiveness Research Protocol Archived June 2, 2011 Comparative Effectiveness and Safety … An Update Research Protocol Archived April 5, 2010 Comparative Effectiveness and Safety … Report Systematic Review Archived September 15, 2008 Comparative Effectiveness, Safety
  18. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-203-adhd-disposition-comments.pdf
    January 01, 2018 - In my assessment, post-marketing surveillance studies of effectiveness and safety are badly missing … These outcomes were seen as being both patient-centered and most critical for decisionmaking across … Effectiveness, safety, and tolerability of lisdexamfetamine dimesylate in children with attention- … A long-term o pen-label safety and effectiveness trial of lisdexamfetamine dimesylate in adolescents … Atomoxetine improves patient and family coping in attention deficit/hyperactivity disorder: a randomized
  19. effectivehealthcare-admin.ahrq.gov/products/patient-centered-medical-home/research-protocol
    December 01, 2019 - as a way of improving patient experiences, outcomes, safety, and system efficiency. 10-12 It is based … Clinical outcomes: Intermediate patient outcomes (e.g., change in HbA1c for diabetic patients). … A systems-based approach to quality, safety, and delivery of evidence-based care. … Clinical outcomes: Intermediate patient outcomes (e.g., change in HbA1c for diabetic patients). … care, superb access to care, and a systems-based approach to quality and safety.
  20. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_disposition-comments.pdf
    October 07, 2011 - daily, which is achieved by doubling the dose at approximately 2-week intervals, as tolerated by the patient … For Results Key Question 2, safety information, please note that ACE inhibitors pose unique, albeit … congestive heart failure, or nephropathy); however all have examined an overlapping set of efficacy and safety … of “class effects”, specifically related to ACEIs and ARBs, discussing that mechanism of action, safety … We underscore the importance of updating any corollary materials (e.g., patient guides) in order to

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