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  1. effectivehealthcare-admin.ahrq.gov/products/uterine-fibroids/research-protocol
    May 01, 2019 - uterine fibroids including MRgFUS systems and power morcellators (see Table A-2 ), though it has issued safety … and tumor characteristics that may predict success or adverse events in patients considered for morcellation … Examples include: baseline characteristics of the patients (e.g., age, menopausal status; symptom status … Laparoscopic Uterine Power Morcellation in Hysterectomy and Myomectomy: FDA Safety Communication, Updated … Available at http://www.fda.gov/MedicalDevices/Safety/AlertsandNotices/ucm424443.htm .
  2. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/lysosomal-storage-diseases-therapies_research-protocol.pdf
    November 15, 2012 - every other week, for the life of the patient. … What are the potential safety issues and harms with ERT? 2. … What published and unpublished studies have reported on the use and safety of this intervention? … Adverse events/harms/safety issues reported 4. … patient and one parent of a child patient will be consulted.
  3. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
    October 18, 2010 - Terbutaline sulfate is commonly used in selected patients as a maintenance therapy to inhibit uterine … Further, as the level of care offered to patients and the level of activity of patients on continuous … subcutaneous terbutaline might differ from that of patients on comparative treatments, we will explore … Therefore, in addition to conducting heterogeneity analyses by other indicators of true preterm labour … to ensure only one event is recorded per patient, in the case the same patient experiences multiple
  4. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment-future_research.pdf
    January 01, 2014 - with patient dropouts. … retention Patients Standardized characterization and reporting of patient and wound characteristics … It is also extremely painful to the patient. … Population Standards for Describing Participating Patients and Their Ulcers Reporting of patient characteristics … , patient-reported and other secondary outcomes.
  5. effectivehealthcare-admin.ahrq.gov/products/ems-blood-transfusion/protocol
    February 01, 2025 - Which component combinations result in the best patient outcomes for which types of patients? … Hospital free days ICU free days Intermediate Outcomes in the prehospital or ED setting Physiological indicators … hemorrhagic shock characteristics (e.g., mechanism of injury/condition, severity, blood pressure, other indicators … MMAT = Mixed Methods Appraisal Tool; NA = not applicable;  NHTSA = National Highway and Transportation Safety … the Funder This project was funded by the National Highway and Transportation Safety
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ems-911-workforce-disposition-comments.pdf
    November 01, 2022 - Background and Purpose, I disagree saying the 911 workers have contact with the public and multiple patients … of the background section to indicate that public-facing EMS clinicians have contact with multiple patients … o acknowledge that exposures may result from activities not involving direct contact with patients … ) evaluation of strategies implemented by 911 call centers that aid in the detection of infectious patients … The Needlestick Safety & Prevention Act of 2000 was passed by the U.S.
  7. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-selection-harms-systematic-reviews.pdf
    February 01, 2018 - 2016. http://www.fda.gov/Safety/MedWatch/HowToReport/ucm053087.htm (accessed October 2, 2017) 1. … Eliciting patient perspective in patient-centered outcomes research: a meta narrative systematic review … Eliciting patient perspective in patient-centered outcomes research: a meta narrative systematic review … EPC reviews should focus on indicators of more severe harms as it is more difficult to interpret the … Eliciting patient perspective in patient-centered outcomes research: a meta narrative systematic review
  8. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_executive.pdf
    April 01, 2013 - KQ 2: For patients with PAH, what are the comparative effectiveness and safety of (a) echocardiography … KQ 3: For patients with PAH, what are the comparative effectiveness and safety of monotherapy or combination … We found no studies describing the safety (or harms) of echocardiography or biomarker testing. … Twenty-eight RCTs involving 3,613 patients evaluated the comparative effectiveness and safety of monotherapy … The mean patient ages ranged from 28 to 50 years old.
  9. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/treatment-resistant-depression_research-protocol.pdf
    December 09, 2009 - when the patient is treatment resistant. … For adults with treatment-resistant depression, do non-pharmacologic interventions differ in safety, … Comparators: ECT, rTMS, VNS, demonstrated effective psychotherapy • Outcomes for each question • Safety … KQ4 focuses on safety issues (adverse effects, adherence) with each of the interventions. … While the patient is ultimately the one to make the decision about whether to receive the non- pharmacologic
  10. S131 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/s131.pdf
    October 01, 2007 - Presented at the Agency for Healthcare Research and Quality meeting on “Comparative Effectiveness and Safety … competitors within a class are often marketed for better efficacy, slightly expanded indications, or better safety … Baseline patient characteristics are presented in Table 1. … the effectiveness and safety of a particular drug that I am about to start and continue to use, compared … , we identified a set of restrictions that analysts should consider in epidemiologic studies of the safety
  11. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update-surveillance-160328.pdf
    March 28, 2016 - $Comparative$efficacy$and$safety$of$aliskiren$and$ irbesartan$in$patients$with$hypertension$and$metabolic … $Antihypertensive$efficacy$and$ safety$of$olmesartan$medoxomil$and$ramipril$in$elderly$patients$with … $ rather$than$hypertensive$ patients),$it$highlights$the$safety$ concerns$associated$with$ combining … $Antihypertensive$efficacy$and$safety$of$olmesartan$medoxomil$and$ ramipril$in$elderly$patients$with … $Comparative$efficacy$and$safety$of$aliskiren$and$irbesartan$in$patients$with$ hypertension$and$metabolic
  12. Layout 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/type-2-diabetes-insulin_executive.pdf
    September 01, 2008 - However, the addition of insulin to treatment Comparative Effectiveness, Safety, and Indications of … A number of patient-related factors have been identified that may help physicians to select patients … Insulin lispro 75/25 was associated with a higher rate of overall hypoglycemia measured as episode/patient … Key Question 4: Effect of premixed insulin analogues based on patient characteristics Comparison of … injection patterns and glucose testing depending on the type of medication regimen prescribed, evaluating patient
  13. effectivehealthcare-admin.ahrq.gov/health-topics/hypoglycemia
    April 19, 2016 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … Effectiveness Research Protocol Archived June 2, 2011 Comparative Effectiveness and Safety … An Update Research Protocol Archived April 5, 2010 Comparative Effectiveness and Safety … Report Systematic Review Archived September 15, 2008 Comparative Effectiveness, Safety
  14. effectivehealthcare-admin.ahrq.gov/products/mental-illness-outcomes/technical-brief
    December 01, 2019 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … implementation; and robust assessments of whether use of such measures improves medical, psychiatric, and patient-centered … practical importance, no studies have assessed whether the use of QMs improves health outcomes for patients … Models White Paper May 31, 2024 Making Healthcare Safer IV: Summary of Findings on PatientSafety Practices and Ratings by a Technical Expert Panel, 2023-2024 Systematic Review
  15. effectivehealthcare-admin.ahrq.gov/products/health-careassociated-infections/research-protocol
    December 01, 2019 - Improving patient safety through infection control: a new healthcare imperative. … Michigan Health and Hospital Association Keystone Center for Patient Safety and Quality. … Shekelle PG, Pronovost PJ, Wachter RM, et al, and the Patient Safety Practices Technical Expert Panel … Assessing the Evidence for Context-Sensitive Effectiveness and Safety of Patient Safety Practices: Developing … Recommended Elements for Reporting on Patient Safety Practices (Source: Shekelle et al. 2010) The
  16. effectivehealthcare-admin.ahrq.gov/products/antipsychotics-children/research-protocol
    December 01, 2019 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … , patient insight into illness. … followup), patient baseline characteristics (diagnosis and age at diagnosis, age, sex, race, weight, … in each group, and the number of patients affected. … Adults Pediatric use: safety & effectiveness not established in patients <18 yr 1. agranulocytosis
  17. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
    September 01, 2011 - As a clinician, I want to know how best to treat an individual patient with a defined subtype of JIA … One patient experiences a hematoma occurring on day 108 which was deemed unrelated to the study drug … Acute infusional adverse events were reported in one (2%) patient in the abatacept group and two (3% … All studies of safety were addressed in KQ3. … Of the 14 patients enrolled in the infliximab arm, 5 patients failed to complete 12 months – 4 because
  18. effectivehealthcare-admin.ahrq.gov/health-topics/digestive-diseases?page=1
    March 14, 2012 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … Research Protocol Archived March 13, 2012 Gene Expression Profiling for Predicting Outcomes in Patients … October 4, 2010 Effectiveness of Recombinant Human Growth Hormone (rhGH) in the Treatment of Patients … Disease Research Protocol Archived August 5, 2010 Comparative Effectiveness and Safety … Agents for Metastatic Colorectal Cancer Research Report December 2, 2009 Comparative Safety
  19. effectivehealthcare-admin.ahrq.gov/products/patient-centered-medical-home/research-protocol
    December 01, 2019 - as a way of improving patient experiences, outcomes, safety, and system efficiency. 10-12 It is based … Clinical outcomes: Intermediate patient outcomes (e.g., change in HbA1c for diabetic patients). … A systems-based approach to quality, safety, and delivery of evidence-based care. … Clinical outcomes: Intermediate patient outcomes (e.g., change in HbA1c for diabetic patients). … care, superb access to care, and a systems-based approach to quality and safety.
  20. effectivehealthcare-admin.ahrq.gov/health-topics/diabetes-medicines
    November 29, 2016 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … Mellitus Research Protocol Archived June 2, 2011 Comparative Effectiveness and Safety … Therapy Research Protocol Archived April 5, 2010 Comparative Effectiveness and Safety … Report Systematic Review Archived September 15, 2008 Comparative Effectiveness, Safety … Study to Assess Association of Variations in OCT Genes with Effectiveness of Metformin in Diabetic Patients

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