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Showing results for "patient safety indicators".
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241. #05 DEPRESSION (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - Adoption could be limited by ketamine’s cost, inconsistent clinical trial data, and safety risks, multiple … But one expert with a research 5 background, citing ketamine’s safety risk and lack of long-term … be limited; these experts cited ketamine’s safety risks and lack of robust clinical trial data as … In contrast, scopolamine’s known safety profile and possible oral and patch delivery options, bolstered … A study to evaluate the safety and efficacy of intranasal esketamine in treatment-resistant depression

242. Enzyme Replacement Therapy for Lysosomal Storage Disorders | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/lysosomal-storage-diseases-therapies/research-protocol
     December 01, 2020 - every other week, for the life of the patient. … What are the potential safety issues and harms with ERT? … What published and unpublished studies have reported on the use and safety of this intervention? … studies Concurrent/prior treatments Length of follow up Outcomes measured Adverse events/harms/safety … patient and one parent of a child patient will be consulted.

243. Neurologic Diseases | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/neurologic-diseases?page=4
     January 24, 2011 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … Crohn’s Disease Research Protocol Archived August 5, 2010 Technical Brief: Use and Safety … Archived August 5, 2010 Comparative Effectiveness and Safety of Analgesics for Osteoarthritis … Delivery Research Protocol Archived July 1, 2010 Evaluation of Effectiveness and Safety … of Antiepileptic Medications in Patients with Epilepsy Research Report Archived May

244. Pulmonary Arterial Hypertension: Screening, Management, and Treatment | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/hypertension-pulmonary-arterial/research-protocol
     December 01, 2019 - Question 2 For patients with PAH, what is the comparative effectiveness and safety of a) echocardiography … outcomes (patient outcome efficacy)? … Question 3 For patients with PAH, what is the comparative effectiveness and safety of monotherapy or … PICOTS Criteria Population(s): KQ 1: Patients with suspected PAH and asymptomatic patients at high … disorder such as scleroderma) KQs 2 and 3: Patients with PAH KQ 1: Patients have neither 1

245. Technical Brief 13: Gene Expression Profiling for Predicting Outcomes in Stage II Colon Cancer (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_technical-brief.pdf
     December 01, 2012 - Patient-oriented and patient-advocacy Web sites for colon cancer were searched. … These GEP assays are all prognostic indicators. Table 1. … The FDA addresses the safety and effectiveness of diagnostic tests and the quality of the design and … Historically, the FDA has subjected test kits to premarket review of safety and effectiveness, but not … result from both preanalytic factors (e.g., sample preparation) as well as analytic factors (such as reagents

246. Asthma-Immunotherapy-2010 Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2010_research-protocol.pdf
     January 01, 2010 - KQ 2 What is the evidence for safety of SIT in patients with allergic rhinoconjunctivitis and/or … products, based on AgE content, but this was never implemented. 4.CBER provides two US standard reagents … only "change in skin test reactivity" (in-vivo) and "change in antibody" (in-vitro) are accepted indicators … Not all patients with asthma are allergic. … The activity domain contains 5 ‘patient-specific’ questions.

247. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
     August 22, 2008 - the most recent data in 2006 (37 year survival).2 The estimated annual direct medical costs per CF patient … KQ 6: In patients with CF, how is efficacy, effectiveness, safety or adverse events impacted by rhGH … KQ 7: In patients with CF, how do the efficacy, effectiveness, safety or adverse events of treatment … followup, and disease state (CF, idiopathic short stature, or growth hormone deficiency)], patient … Patient Registry Annual Report 2006. Bethesda, MD: Cystic Fibrosis Foundation; 2008. 3.

248. Disposition of Comments for Venous Thromboembolism Prophylaxis in Orthopedic Surgery (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_disposition-comments.pdf
     March 01, 2012 - Despite recent advances in patient care, fatal pulmonary embolism occurs in 0.1 - 0.5% of these patients … A separate question is whether there are patient risk factors associated with VTE events in patients … We propose the following rubric: 1, Efficacy; 2, Safety; 3, Cost. … 2) Improved Efficacy; No improvement in Safety 3) No improvement in Efficacy; Improved Safety 4) No … Furthermore, in the clinical trials, highly selected patient groups were used (excluding patients felt

249. uterine-fibroids-protocol-160301 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
     March 01, 2016 - including MRgFUS systems and power morcellators (see Table A-2 in Appendix), though it has issued safety … and tumor characteristics that may predict success or adverse events in patients considered for morcellation … Examples include: baseline characteristics of the patients (e.g., age, menopausal status; symptom status … Laparoscopic Uterine Power Morcellation in Hysterectomy and Myomectomy: FDA Safety Communication, Updated … Available at http://www.fda.gov/MedicalDevices/Safety/AlertsandNotices/ucm424443.htm. 19.

250. Psoriasis-Chronic Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_executive.pdf
     November 01, 2012 - In patients with chronic plaque psoriasis, what is the comparative safety of systemic biologic agents … To be included, the patient population evaluated in the study must have been adult patients (≥18 years … In an RCT that compared the efficacy and safety of adalimumab with placebo in patients with moderate … Study Evaluating the Efficacy and Safety of Etanercept and Acitretin in Korean Patient With Moderate … Safety and efficacy study on etanercept in patients with plaque psoriasis.

251. Obesity (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1512.pdf
     December 01, 2015 - balloon removal from other teams’ patients (3 patients, 0.11%), and at 1 patient (0.03%) each, Wernick … Patients were reported to have generally tolerated the balloon well, with one early removal for patient … greatly and limit patient acceptance, although patient interest in the procedure would likely remain … Perioperative safety in the longitudinal assessment of bariatric surgery. … Safety of antiobesity drugs. Ther Adv Drug Saf. 2013;4(4):171-81.

252. Dietary Proteins | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/dietary-proteins?page=4
     March 09, 2010 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … Agents Systematic Review Archived September 15, 2008 Comparative Effectiveness, Safety … in Adults Systematic Review Archived July 16, 2007 Comparative Effectiveness and Safety … Archived May 23, 2006 Comparative Effectiveness of Epoetin and Darbepoetin for Managing Anemia in Patients … Study to Assess Association of Variations in OCT Genes with Effectiveness of Metformin in Diabetic Patients

253. Core Functionality in Pediatric Electronic Health Records | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/pediatric-ehr/technical-brief
     December 01, 2019 - support the work of child health care providers and assure the delivery of quality care to pediatric patients … medication dosing, pediatric disease management, pediatric norms, and the relationship between pediatric patients … that if these functionalities are implemented well, the EHR will also better support the care of all patients … medical home; (2) a desire to support and maintain patient safety; and (3) the increasing presence of … Safety Practices and Ratings by a Technical Expert Panel, 2023-2024 Technical Brief May

254. Topic Brief: Interventions to Decrease Hospital Length of Stay (pdf file)
     effectivehealthcare-admin.ahrq.gov/system/files/docs/topic-brief-hospital-length-of-stay.pdf
     November 01, 2019 - at a safety net hospital. … in the Safety Net: Results of a Randomized Controlled Trial. … Shift-to-Shift Handoff Effects on Patient Safety and Outcomes. … Effect of Telehealth Interventions on Hospitalization Indicators: A Systematic Review. … Hospitals and health systems, including CEOs, will use this information to improve patient safety and

255. Vte-Prophyalaxis Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_executive.pdf
     May 01, 2013 - The burden of VTE is higher among some patient populations, including patients who have experienced … and safety of pharmacologic strategies for VTE prevention in patients with liver disease. … effectiveness and safety of pharmacologic strategies among patients with liver disease. … in the patient populations. … RCTs should evaluate the comparative effectiveness and safety of LMWHs in obese patients.

256. Clinical Effectiveness of Coronary Stents in the Elderly: Results From 262,700 Patients in the American College of Cardiology-National Cardiovascular Data Registry | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/coronary-stents-outcomes/research
     January 01, 2020 - Thus we are unable to directly address some important questions which have been raised regarding the safety … Effectiveness and Safety of Drug-Eluting Stents in Ontario. N Engl J Med 2007;357:1393-1402. … Balancing Efficacy and Safety of Drug-Eluting Stents in Patients Undergoing Percutaneous Coronary Intervention … Safety and Efficacy of Sirolimus- and Paclitaxel-Eluting Coronary Stents. … Unadjusted baseline characteristics of patients in study population Patient Characteristics

257. Making Sure That Evidence Is Understood and Used (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/epc-making-sure-evidence-understood.pdf
     July 01, 2020 - Department of Health and Human Services that is charged with improving the quality, safety, efficiency … What information is needed to make better recommendations to patients? … Consumers, patients, caregivers, and patient advocacy organizations It is vital that research answer … with accurate, independent, scientifically rigorous information for comparing the effectiveness and safety … Patient, Population or Problem: ◆ The “P” in PICO(TS) is a description of the patient(s) of interest

258. Methods-Guide-Chapter-Prioritization-And-Selection-Of-Harms-For-Inclusion-In-Systematic-Reviews (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
     February 01, 2018 - The workgroup suggests that EPC reviews focus on indicators of more severe harms (e.g., “serious” adverse … 9) How should input from technical and clinical experts and patients or patient advocacy groups be used … How should input from technical and clinical experts and patients or patient advocacy groups be used … Had to report data from groups of in which at least 85% of the patients were from one of the patient … What are the harms of therapeutic interventions for patients with ME/CFS and how do they vary by patient

259. Untitled (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/field-triage-glascow_research-protocol.pdf
     February 25, 2016 - severity score ≥16, head AIS score >2 or >3, presence of intracranial hemorrhage, and utilization indicators … •   KQ1: Predictive utility for mortality, morbidity, injury severity score ≥16,25 or utilization indicators … score  of  Glasgow   Coma  Scale Intermediate   outcomes Over-­  or  under-­ triage   Utilization  indicators … National Highway Traffic Safety Administration. Washington, DC. … patients.

260. Allergy-Seasonal Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/allergy-seasonal_executive.pdf
     July 01, 2013 - effective during pregnancy, but their use may be restricted because of concerns about maternal and fetal safety … treatment for mild SAR • The comparative effectiveness and safety of SAR treatments used in combination … all outcomes of interest were patient reported. … SAR/PAR results (N = 4) ● Unable to obtain article (N = 2) ● Incomplete data (N = 1) ● Efficacy/safety … magnitude and direction of change in drug disposition may facilitate application of effectiveness and safety