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161. Key Questions 1. Does routine preoperative testing compared to no testing or alternative testing strategies improve outcomes (such as surgical complications, other morbidity, and mortality) among patients undergoing elective surgery? 2.… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/key-questions-1-does-routine-preoperative-testing-compared-to-no-testing-or-alternative-testing-strategies-improve-outcomes-such-as-surgical-complications-other-morbidity-and-mortality-among-patients-undergoing-elective-surg
     November 01, 2017 - tests change patient management decisions? … What patients or group(s) of patients does your question apply to? … safety,1 eliminate delays,15 limit harm from unnecessary follow-up of abnormal tests,7,14 improve system … safety,1 eliminate delays,15 limit harm from unnecessary follow-up of abnormal tests,7,14 improve system … This topic impacts all pre-surgical patients.

162. Management of Suspected Opioid Overdose With Naloxone by Emergency Medical Services Personnel - Executive Summary (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
     November 01, 2017 - arrest, function, quality of life, other clinical sequelae of opioid overdose; health care utilization indicators … National Highway Traffic Safety Administration. The national EMS scope of practice model. … Joint meeting of the anesthetic and analgesic drug products and the drug safety and risk management … Joint meeting of anesthetic and analgesic drug products advisory committee and drug safety and risk … Randomized controlled trial comparing the effectiveness and safety of intranasal and intramuscular

163. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
     October 01, 2011 - We also included studies that report safety in patients with rheumatoid arthritis or who were taking … ), diclofenac (10/100 patient-years), and ibuprofen (11/100 patient-years). … disease prevention, usually at lower prophylactic doses GI harms: A systematic review of individual patient … though diclofenac was associated with the highest rate of hepatic laboratory abnormalities (78/1000 patient … - years, vs. 16 to 28/1000 patient-years for the other NSAIDs).

164. Refining Key Questions: Interactive Case Study Quiz
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rfviia.pptx
     May 01, 2010 - The talk will cover the current evidence on the effectiveness and safety of using recombinant activated … Safety and efficacy of recombinant activated factor VII: a randomized placebo-controlled trial in the … Efficacy and safety of repeated perioperative doses of recombinant factor VIIa in liver transplantation … Safety and efficacy of a single bolus administration of recombinant factor VIIa in liver transplantation … Safety is defined via thromboembolic events and mortality, but individual studies often lack the statistical

165. Refining Key Questions: Interactive Case Study Quiz
     effectivehealthcare-admin.ahrq.gov/sites/default/files/rfviia.pptx
     May 01, 2010 - The talk will cover the current evidence on the effectiveness and safety of using recombinant activated … Safety and efficacy of recombinant activated factor VII: a randomized placebo-controlled trial in the … Efficacy and safety of repeated perioperative doses of recombinant factor VIIa in liver transplantation … Safety and efficacy of a single bolus administration of recombinant factor VIIa in liver transplantation … Safety is defined via thromboembolic events and mortality, but individual studies often lack the statistical

166. C- Evidence-based Practice Center Technical Brief Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/musculoskeletal-disorders-imaging_research-protocol.pdf
     August 05, 2010 - Evidence-based Practice Center Technical Brief Protocol Project Title: Technical Brief - Use and Safety … It requires that the patient be placed in a tube lying flat, either prone or supine. … What are the potential safety issues and harms of positional MRI technologies? … i Types of patients/patient selection criteria: inclusion and exclusion criteria, characteristics of … enrolled patients (demographics, disease spectrum).

167. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/gerd_executive.pdf
     September 01, 2011 - are made in the report, its conclusions should have clinical applicability because they laid out the safety … Objective outcomes addressed include esophagitis healing, ambulatory pH, other indicators of reflux, … placebo in improving asthma symptoms, nocturnal asthma, or use of asthma medications, or in objective indicators … Administrative databases can provide additional data for addressing long-term safety issues. … Objective outcomes addressed include esophagitis healing, ambulatory pH, other indicators of reflux,

168. Obesity (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1306.pdf
     July 01, 2013 - safety evaluation. … , thus disrupting the current health care model for this patient population. … data and postmarket safety evaluation—set forth by FDA. … data and postmarket safety evaluation—set forth by FDA. … would view lorcaserin if it demonstrates safety and efficacy in a majority of patients.

169. Obesity (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - of administration would be unlikely to deter liraglutide use if it demonstrates safety and efficacy … Duo positively if it demonstrates safety and efficacy in clinical trials. … , thus disrupting the current health care model for this patient population. … data and postmarket safety evaluation—set forth by FDA. … if it demonstrates both short- and long-term safety and efficacy in a majority of patients.

170. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ischemic-stroke-treatment_executive.pdf
     January 01, 2011 - report: author identification, year of publication, study design characteristics, study population, patient … different types of neurothrombectomy devices, what are the type(s) of devices, study designs and sizes, patient … patient discharge. … We did not draw conclusions regarding their effectiveness or safety. … the topic, including randomized controlled trials to determine the optimal device(s) to use, and the patient

171. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1506.pdf
     June 01, 2015 - abuse by increasing the perceived safety of a harmful behavior. … Commercial clients pay annual licensing fees for CaringTXT, prorated on projected patient populations … CaringTXT annual licenses cost about $12,000 to $18,000 for an average-sized university or college client … Across all client types, patients pay for text messages only if the service is not included in their … As of June 2015, CaringTXT was in use by clients including the University of Pittsburgh and the Central

172. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
     June 16, 2010 - The 2006 CER revealed safety concerns for the erythropoietic stimulants as a class. … In an individual patient data meta-analysis of 13,933 patients in 53 trials treated with epoetin alfa … analyzed individual patient data from 2,122 patients in 6 trials receiving darbepoetin alpha finding … Study and Independent Patient Level Meta-Analysis Selection: Results from study- and patient-level meta-analysis … Erythropoietin or Darbepoetin for patients with cancer--meta-analysis based on individual patient data

173. Obesity (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - were uncertain regarding long-term safety and efficacy. … The yearly cost per patient would be about $13,000 at current pricing. … , which has yet to be established in this patient population. … declining because of safety concerns. … for similar reasons, but mentioned long-term safety as a concern.

174. Public-Reporting-Cost-Measures Technical-Brief (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/public-reporting-cost-measures_technical-brief.pdf
     March 01, 2015 - organization that provides online information about health care quality and patient safety for consumers … http://www.cthosp.org/advocacy/quality-and-patient-safety/hospital-quality- reporting-website/ RWJF … a=3132&q=388090 http://www.cthosp.org/advocacy/quality-and-patient-safety/hospital-quality-reporting-website … / http://www.cthosp.org/advocacy/quality-and-patient-safety/hospital-quality-reporting-website/ http: … http://www.sts.org/quality-research-patient-safety/sts-public-reporting-online RWJF Excluded 214.

175. Making Healthcare Safer IV: Summary of Findings, 2023-2024 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mhs-IV-1-year-final-report-updated-title_0.pdf
     May 01, 2024 - Director, General Patient Safety Program Center for Quality Improvement and Patient Safety Agency … effectiveness of patient safety practices (PSPs). … safety progress,”7 a claim supported by a recent meta- analysis indicating that as many as 1 in 20 patients … the purpose of improving patient safety. … safety practices Patient Safety Practice Summary of Final Advice Categorization of Final Advice 1

176. Insulin Delivery and Glucose Monitoring Methods: Future Research Needs (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/insulin-blood-sugar_research.pdf
     August 01, 2015 - Patient Stakeholder Baltimore, MD Ruth Horowitz, M.D. … Study design: Allocation: Randomized Endpoint Classification: Safety/Efficacy Study Intervention … Study design: Endpoint Classification: Safety Study Intervention Model: Single Group Assignment … Study design: Allocation: Randomized Endpoint Classification: Safety/Efficacy Study Intervention … Study design: Allocation: Randomized Endpoint Classification: Safety/Efficacy Study Intervention

177. Recombinant-Factor-Viia Clinician (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/recombinant-factor-viia_clinician.pdf
     October 01, 2010 - . ��� Increased risk for arterial thromboembolic events, particularly at doses >40 µg/kg of patient … though the effect of treating spontaneous intracranial hemorrhage with rFVIIa at doses ≤40 μg/kg of patient … rFVIIa) in the hospital setting has increased despite limited comparative data on its effectiveness and safety … How is it being used, and what is the evidence of benefits and harms for treated patients? … In-Hospital, Off-Label Use of rFVIIa TE Events/Total Patients (%) Risk Difference Summary Effect Size

178. Disposition of Comments for CER 195 Management of Uterine Fibroids (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-195-disposition-comments-uterine-fibroids.pdf
     December 14, 2017 - Due to safety issues, the use of leuprolide is limited for only 3 months. … bleeding and statistically significant improvements in women’s symptom and health-related quality-of-life indicators … had much less time to get pregnant than the myomectomy patients. … US patients are different than European (or other patients) in that there is greater direct appeal by … pharma, device companies and providers to the consumer (patient).

179. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/patient-safety-practices_research-protocol.pdf
     November 09, 2011 - , routine surveillance for patients at admission  Identifying patients at risk for suicide  … safety practice is applied to a patient safety problem in order to improve beneficial patient safety … Safety Practice Patient Safety Problem Contexts - Safety Culture, Teamwork, Leadership … of Patient Safety Practices – Developing Criteria 3 I. … Assessing the Evidence for Context-Sensitive Effectiveness and Safety of Patient Safety Practices:

180. Prehospital Airway Management | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/prehospital-airway-management/research
     August 01, 2021 - EHC The Evidence-based Practice Centers The Scientific Resource Center Registry of Patient … Construct comparisons that are more clearly defined by specific emergency types, patient groups, and … No conclusion was supported by high SOE for any comparison and patient group. … 14, 2021 Systematic Review AHRQ and the National Highway Traffic Safety … Safety Practices and Ratings by a Technical Expert Panel, 2023-2024 Rapid Evidence Product