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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
December 01, 2011 - If a patient has responded to one agent in the past,
is that agent better than current alternatives at … For adults with a depressive syndrome, do
commonly used antidepressants differ in safety,
adverse events … No evidence addressed how second-generation
antidepressants compare when a patient responds to one
agent … Furthermore, studies need to explore patient
preferences about dosing regimens and the level of
acceptance … Finally, no evidence addressed how second-generation
antidepressants compare when a patient responds
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-202-thermoplasty-comments.pdf
December 14, 2017 - Effectiveness and Safety of Bronchial
Thermoplasty in Management of Asthma. … Safety and
feasibility of bronchial thermoplasty in asthma patients with
very severe fixed airflow … Safety and Feasibility of Bronchial
Thermoplasty in Asthma Patients with Very Severe Fixed
Airflow … PAS2 study patients treated with BT showed procedural safety
and clinical improvements during each of … , no information is available regarding BT’s
safety and efficacy in a broader population of patients
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effectivehealthcare-admin.ahrq.gov/products/diabetes-claims-data/research
November 01, 2017 - EHC
The Evidence-based Practice Centers
The Scientific Resource Center
Registry of Patient … We used this review to determine which glycemic indicators should be assessed to determine the adequacy … In both patient cohorts, we described comorbidities present when DMT2 was diagnosed and medications used … Conclusions
By conducting similar analyses in both patient populations, we could discern the value … Text-mining methods may be useful for ascertaining information critical to research studies and drug safety
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effectivehealthcare-admin.ahrq.gov/products/migraine-future/research
December 01, 2019 - EHC
The Evidence-based Practice Centers
The Scientific Resource Center
Registry of Patient … The review was motivated by uncertainty around the effectiveness, comparative effectiveness, and safety … Questions (KQs) about the efficacy and comparative effectiveness of these treatments (KQ 1); evaluating the safety … of these treatments (KQ 2); and the identification of patient characteristics that predict the effectiveness … and safety of pharmacologic treatments for preventing migraine attacks in adults (KQ 3).
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effectivehealthcare-admin.ahrq.gov/products/preterm-birth-terbutaline-pump/research-protocol
December 01, 2019 - Terbutaline sulfate is commonly used in selected patients as a maintenance therapy to inhibit uterine … Further, as the level of care offered to patients and the level of activity of patients on continuous … subcutaneous terbutaline might differ from that of patients on comparative treatments, we will explore … Therefore, in addition to conducting heterogeneity analyses by other indicators of true preterm labour … to ensure only one event is recorded per patient, in the case the same patient experiences multiple events
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effectivehealthcare-admin.ahrq.gov/products/rheumatoid-arthritis-hospitalizations/research
January 01, 2020 - EHC
The Evidence-based Practice Centers
The Scientific Resource Center
Registry of Patient … patients with rheumatoid arthritis (RA). … fraction of 65% without further details and 1 had a report indicating normal ventricular function in a patient … with RA and could be used in assessments of medication safety. … Inpatients
White Paper
May 31, 2024
Making Healthcare Safer IV: Summary of Findings on Patient
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-hospitalizations_research.pdf
October 01, 2008 - about the outcomes, clinical effectiveness, safety, and appropriateness of health care items and
services … and we are evaluating the safety of tumor necrosis factor alpha
(TNF-α) antagonists in a cohort of … patients with rheumatoid arthritis (RA). … fraction of 65% without
further details and 1 had a report indicating normal ventricular function in a patient … with RA and could be used in assessments of medication safety.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/s96.pdf
October 01, 2007 - Findings
from NEISS-CADES can help design and prioritize patient safety
interventions for outpatient … Commission before dissemination of
results to patients, clinicians, and public health practitioners. … In
February and March 2006, 2 FDA Drug Safety Advisory
Panels addressed the safety of stimulant drugs … Con-
sumer Product Safety Commission; March 2000.
10. … Adverse drug events
in emergency department patients. Ann Emerg Med. 2002;39:258–267.
28.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
June 01, 2014 - surgery, but choose to decline due to safety concerns. … for similar reasons, but mentioned long-term safety to be a concern. … health, many expressed concerns regarding long-term safety and efficacy. … data and postmarket safety evaluation—set
forth by FDA. … potential impact on patient health.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-256-telehealth-women-disposition-comments.pdf
June 16, 2022 - reported outcomes, patient satisfaction in care and patient adherence
to visits via telehealth approaches … decision aid rather than
safety planning? … Both qualitative and
patient reported outcomes are
included. … The outcomes is increased use of helpful safety
behaviors, not simply increase use of safety behaviors … Patients boycotted.
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effectivehealthcare-admin.ahrq.gov/products/mental-health-apps/protocol
January 01, 2023 - mental health apps, causes providers to be hesitant about recommending apps. 7 Most providers and patients … including health literacy, 508 compliance, digital equity, and cost; usability and acceptability by patients … /clients and health care providers; security and privacy features such as data usage and sharing of data … Key substance use and mental health indicators in the United States: Results from the 2019 National Survey … They may include clinical experts, patients, manufacturers, researchers, payers, or other perspectives
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effectivehealthcare-admin.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1406.pdf
January 01, 2020 - Experts wanted to see additional clinical trial data assessing
baclofen’s long-term safety and efficacy … Additionally, safety reporting from a bioavailability study in healthy volunteers
noted similar adverse … All adult volunteers, and 15 of 19 adolescent
volunteers were able to successfully remove the safety … The devices are not intended for laypersons and do not appear to have the audible
instructions, LED indicators … or increased risk of opioid
overdose.45 Overall, experts noted that because of Evzio’s extensive safety
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effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/pico-1-populations-children-with-infantile-hemangiomas-ihs-interventions-early-referral-comparators-delayed-referral-outcomess-minimization-of-functional-impairment-andor-cosmetic-deformity-pico-2-populations-children-with
November 01, 2017 - EHC
The Evidence-based Practice Centers
The Scientific Resource Center
Registry of Patient … We would like to assess the difference in outcomes in patients referred early vs. those for whom referral … The other analyses would compare: 1) safety and efficacy of the two primary medical interventions for … IHs, propranolol and corticosteroids, 2) safety and efficacy of pulsed dye laser treatment of IHs to … that of no treatment, and 3) safety and efficacy of imaging to that of no imaging
The population
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/distributed-network-ambulatory-therapeutics_research.pdf
July 01, 2009 - the best practices of high-
performing member practices, which are identified by comparing quality indicators … data or to patients. … The findings of our safety analyses suggest
that sulfonylureas may put patients at increased risk of … and improved quality of care for patients. … data or to their patients.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/vte-prophyalaxis_research-protocol.pdf
March 01, 2011 - There is clinical uncertainty about the
optimal choice of VTE prophylaxis in this patient population … This CER will evaluate the comparative effectiveness and safety of
pharmacologic prophylaxis among patients … What is the comparative effectiveness and safety of IVC filters to prevent PE in hospitalized
patients … and individual patient risk factors. … Deep-vein thrombosis: advancing awareness to protect patient lives.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/mental-health-app-protocol-updated.pdf
January 01, 2018 - researchers, health care providers,
informaticians and technologists, app developers, as well as patient … We plan to have a separate call for patient/caregiver KI at the start of the
project, with questions … /clients and health care providers;
security and privacy features such as data usage and sharing of … Key substance
use and mental health indicators in the United States: Results from the 2019 National … how it works, how it is currently
used or might be used, and which features may be important from a patient
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rapid-assessment-research-updates_research.pdf
September 15, 2008 - In doing so, CERs more closely parallel the decisions facing clinicians, patients and
policymakers, … • Has there been a change in scope (e.g., new patient populations, new outcomes)? … Comparative Effectiveness of Epoetin and Darbepoetin for Managing Anemia in
Patients Undergoing Cancer … of medical, surgical, and
endoscopic treatments for improving objective and subjective outcomes in patients … Yes/No Yes/No Yes/No
7
10 percent to 65 percent of surgical
patients still require medications
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
September 01, 2012 - associated
with preterm birth represent untold
distress for families, as well as significant
costs to patients … However, these groups also note interest
in assessing long-term safety because the
Effective
Health … How do the effectiveness, adverse effects, and safety
of progestogen treatment differ based on the maternal … How do the effectiveness, acceptability, adherence,
adverse effects, and safety of progestogen treatment … One survey
addressed patient demand; 63 percent reported that patients
“never request”; 35 percent,
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effectivehealthcare-admin.ahrq.gov/products/psoriasis-chronic/research-protocol
December 01, 2019 - the main research gaps identified in this meta-analysis was the lack of comparative effectiveness and safety … Question 2
In patients with chronic plaque psoriasis, what is the comparative safety of systemic biologic … followup), patient baseline characteristics (including whether the patient is naïve to biologic therapy … Since differences in efficacy or safety may exist between agents within a given class (e.g., two biologic … We will also conduct subgroup analyses based on the patient population evaluated, including patients
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effectivehealthcare-admin.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1406.pdf
June 01, 2014 - Preliminary data for these interventions
are promising, and ongoing trials are clarifying the safety … Results and Discussion of Comments
Seven experts, with clinical, research, patient safety, and health … widespread, if data support its efficacy and safety, the experts thought. … Investigators reported high
patient adherence (81% and 94%; adherence defined as patients completing … that SPARX could positively affect patient health outcomes
by providing an alternative for patients