-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/high-cholestorol-medicines-update_research-protocol.pdf
December 31, 2013 - paucity of evidence to address this question, so
they conducted additional analyses unrestricted by patient … The results will help provide an evidence base for future practice guidelines to
influence patient management … We will include adults at moderate and high risk of CVD (the previous report had no
restrictions by patient … Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-‐analysis of data
from … Lipid-‐altering
efficacy
and safety
of
ezetimibe/simvastatin versus atorvastatin in patients
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-decision-models_methods.pdf
July 01, 2012 - Most often, evidence on diagnostic performance, effectiveness and safety of interventions
and testing … , patient adherence, and costs is available from different studies. … Essentially, one would evaluate three categories of
attributes: the cost and safety of testing; the … Scenario B: For patients with mild cognitive impairment, could PET be used to identify a
group of patients … The evidence report also modeled hypothetical treatments with various effectiveness and safety profiles
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-251-integrated-pain-management-evidence-summary.pdf
October 01, 2021 - Contextual Questions related to program models and components, their cost,
safety and applicability … Evidence on the impact of program types/components, coordination, and methods of
care delivery on patient … Specifics of pain diagnoses or characteristics
and patient factors were not generally reported in studies … Programs that address a range of biopsychosocial
aspects of pain, tailor components to patient need, … Included IPMP programs in particular focused
on patient-tailored care and were generally low intensity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/wheelchair-service_technical-brief.pdf
January 01, 2012 - Client satisfaction
survey of a wheelchair seating clinic. … Patients/Patient Advocates 1. What has your experience been with different types of payers?
2. … Cases included clients
assessed by
telerehabilitation by
the GlenRose Seating
Service based in
Edmonton … , comfort,
satisfaction
Not reported
Pimentel, 200858
To explore
assessment practices
for clients … sectional/Qualitative
N=35
Evaluation of new
assessment practices
focusing on soliciting
goals from clients
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-nomination-bone-metastases.pdf
February 01, 2017 - However, SBRT efficacy and safety data are derived from
lower quality studies with variable exclusion … Practitioners should closely adhere to quality and safety
considerations for SBRT delivery as described … Once again, practitioners should use existing ASTROwhite
paper safety recommendations.14 In general, … ASTRO guidelines present scientific, health, and safety
information and may reflect scientific or medical … Quality and safety
considerations in stereotactic radiosurgery and stereotactic body radiation
therapy
-
effectivehealthcare.ahrq.gov/sites/default/files/01_arthritis_potential_high_impact_2012-12-10.pdf
January 01, 2012 - The
investigators reported that patients treated with MSC therapy had improvements in patient pain … stated MSC therapy is
investigational because of insufficient evidence or insufficient long-term safety … Both groups had
similar safety profiles.
29
In a study of patients with knee OA (Outerbridge grades … Because PRP is theorized to be more effective in younger patients, the
treatment could alter patient … These safety concerns could present significant barriers to diffusion.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/skin-cancer_research-protocol.pdf
August 10, 2016 - complexity of this decisionmaking process is a lack of
clarity regarding the comparative efficacy and safety … clinicians, and payers to have reliable estimates
of KC treatments’ comparative effectiveness and safety … this systematic review is to comprehensively collect information on the comparative
effectiveness and safety … Patient Satisfaction Questionnaire-18, Skin Cancer Index patient
satisfaction subscale)
• Mortality … Comments About the Eligibility Criteria
Because the key questions are about comparative effectiveness and safety
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
July 13, 2011 - If a patient has responded to one agent in the past, is that agent better than
current pharmacologic … KQ4a: For adults with a depressive syndrome, do second-generation antidepressants
differ in safety, … b: Are there any differences in safety, adverse events, or adherence between
immediate release and … symptoms (anxiety, insomnia, melancholia, pain, psychomotor changes, and
somatization), KQ4 focuses on safety … Because we do not have access to individual patient data, we will not conduct any
subgroup analyses.
-
effectivehealthcare.ahrq.gov/sites/default/files/s116.pdf
October 01, 2007 - pharmacoepidemiology, prescribing
(Med Care 2007;45: S116–S122)
Observational studies are necessary to evaluate the safety … For the IV to be defined
for each patient, we excluded each physician’s first patient
from the cohort … Characteristics of Cohort
Patient Characteristics N %
Female patient 12,545 81.5
Age �80 10,750 70.0 … Indeed, in a comparative
safety study of APMs in a population of seniors in British
Columbia, Canada, … 0.78 �0.58, 1.02� 0.07
Patient of PCPs 0.98 �0.70, 1.39� 0.93
Long-acting benzodiazepines All patients
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes_hi_impact.pdf
March 01, 2012 - the surgery in this
patient population. … Along with
updates to safety information about ongoing or completed studies, included in the response … Experts expressed a desire for further
data evaluating safety and efficacy of these modifications to … combination therapy (with oral hypoglycemic agents and insulin)
and to assess its cardiovascular safety … That FDA committee
voted to not recommend approval because of safety concerns and the company submitted
-
effectivehealthcare.ahrq.gov/sites/default/files/ahrq-healthcare-horizon-scan-protocol-operations-manual_130826.pdf
August 01, 2013 - Anticipated Cost Per Patient (if known)
11. … Potential Patient and Clinical Staff Safety Issues
14. … Patient Safety Issues (if applicable)
11. Required Resources
12. … Safety data that could change perspectives
4. … A patient safety alert been issued that could signal a safety/efficacy change in
perspectives?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-infertility_research.pdf
June 01, 2017 - The objectives of this SR are to evaluate
the comparative safety and effectiveness of treatment strategies … The KQs are listed below:
KQ 1: What are the comparative safety and effectiveness of available treatment … KQ 2: What are the comparative safety and effectiveness of available treatment strategies for
women … KQ 4: What are the comparative safety and effectiveness of available treatments for women with
tubal … Both trials were applicable to KQ 1 and had a combined
sample size of 340 patients.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_disposition-comments.pdf
January 01, 2010 - Further,
small studies [Phase I (safety); Phase II (dose-
ranging; mechanistic)] may show effects which … larger study subject enrollment,
selection of a proper dose, and refinement of
study methods to reduce patient … geographic
factors (intensity of pollen exposure;
confounding allergens; topography), degree of
patient … off label use of licensed
products for SLIT by physicians who are falsely
comforted by the current safety … controlled European clinical trials that
demonstrated clinical efficacy and a sufficient
degree of safety
-
effectivehealthcare.ahrq.gov/sites/default/files/12_pregnancy_potential_high_impact_2012-12-11.pdf
January 01, 2012 - milk from a
source other than her own, only milk from a source that has been screened to ensure its safety … intervention.
15-21
All experts saw a significant unmet need for more
innovative ways to supply VLBW patients … All experts agreed that donor human milk has the potential to significantly improve patient
health … Overall, experts agreed that although more safety and efficacy studies must be performed to
determine … Food and Drug Administration Center
for Food Safety and Applied Nutrition; 2010 Dec
6. 6 p.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_clinician.pdf
January 01, 2016 - review updates a 2008 report4 and
summarizes the more recent evidence comparing the
effectiveness and safety … Choice of treatment options may be influenced
by factors such as patient age and health at the time … is
referred for surgery, treatment-related convenience and
costs, patient values and preferences, … based on
patient and disease characteristics. … What To Discuss With Your Patients and Their
Caregivers
–� How long the patient may live with his cancer
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/psoriasis-chronic_research-protocol.pdf
January 10, 2012 - To date, no comparative effectiveness review comparing the effectiveness and safety of
FDA-approved … with chronic plaque psoriasis, what is the comparative safety of systemic biologic
agents and systemic … followup),
patient baseline characteristics (including whether the patient is naïve to biologic therapy … We will also conduct
subgroup analyses based on the patient population evaluated, including patients … Efficacy and
safety results from the randomized controlled comparative study of adalimumab vs.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/observational-research-scores_research.pdf
May 01, 2012 - about the outcomes, clinical effectiveness, safety, and appropriateness of health care items and
services … In observational studies assessing beneficial (effectiveness) or adverse (safety) outcomes,
confounding … A common question in pharmacoepidemiologic studies of drug safety is whether the risk
conferred by a … Pharmacoepidemiology and Drug Safety
2008;17:546-555. … Pharmacoepidemiol Drug
Safety 2005;14(7):465-76.
-
effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1312.pdf
December 01, 2013 - designed to cater to
the special needs of the senior population (people aged 65 and older) to improve safety … adherence to medication regimens for chronic diseases and be used in clinical trials to better
understand safety … safety.20,21 During the transition, medications may be altered and self-care
responsibilities increased … effectiveness and safety. … In general, experts called for more substantial
data proving the safety and effectiveness of this care
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/insomnia_clinician.pdf
August 01, 2017 - Therapy: Adverse Effects (See Table 3)
�� Evidence regarding the long-term (more than 3 months)
safety … Evidence regarding their longer-term
efficacy and safety is limited or lacking.
�� Outcome reporting … Key Points for Clinician and Patient and Caregiver
Discussions
�� CBT-I appears to be effective and … Ordering Information
For electronic copies of this clinician research summary, the
companion patient … To order
free print copies of the patient resource, call the AHRQ
Publications Clearinghouse at 800
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/impact-healthcare-algorithms-racial-ethnic-disparities-March-2.pdf
May 15, 2023 - green space, broadband,
economic opportunity, transportation, schools, healthy food
access, public safety … /year (US)
► Market estimates: 150-200 million patients/year (US)
• Common goal: Find patients who are … ET
Supporting Algorithmic Equity in a Public Healthcare
System: a Case Study in Opioid Safety
76 … • Algorithm developers are not subject matter experts in patient
care. … Shah, MBBS, PhD
Supporting Algorithmic Equity in a Public Healthcare System: a Case Study in Opioid Safety