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Total Results: 1,169 records

Showing results for "patient safety".

301. Ch 8-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_8-user-guide-to-ocer_130129.pdf
     October 01, 2013 - ablation for hepatocellular carcinoma compared to resection or no treatment5 and a comparison of the safety … missing biochemistry lab data compared to early-stage patients (6-9% incomplete in early-stage patients … linked to Medicare claims, are a valuable resource that has generated comparative effectiveness and safety … Comparative assessment of the safety and effectiveness of radiofrequency ablation among elderly Medicare … Study design for a comprehensive assessment of biologic safety using multiple healthcare data systems

302. PROPOSALS FOR A PHASED EVALUATION OF (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/whitepaper3-lijmer02262010-2.pdf
     January 01, 2009 - In Phase I, the safety, tolerability and toxicity, pharmacodynamics, and pharmacokinetics of the new … limited numbers of human subjects to gather preliminary evidence regarding effectiveness and additional safety … Phase III refers to controlled clinical studies intended to provide a reasonable assurance of safety … studies performed once a technology has gained marketing approval; these studies address long-term safety … Trials in volunteers usually go before trials in patients.

303. PROPOSALS FOR A PHASED EVALUATION OF (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-tests-proposals_research.pdf
     January 01, 2009 - In Phase I, the safety, tolerability and toxicity, pharmacodynamics, and pharmacokinetics of the new … limited numbers of human subjects to gather preliminary evidence regarding effectiveness and additional safety … Phase III refers to controlled clinical studies intended to provide a reasonable assurance of safety … studies performed once a technology has gained marketing approval; these studies address long-term safety … Trials in volunteers usually go before trials in patients.

304. Attention Deficit Hyperactivity Disorder: Diagnosis and Treatment in Children and Adolescents - Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/deficit-hyperactivity-protocol.pdf
     November 01, 2021 - selection: The domain patient selection addresses whether the selection of patients could have introduced … Patient-centered outcomes are considered direct. … Long-Term Effects of Stimulant Treatment for ADHD: What Can We Tell Our Patients? … Safety of Vaccines Used for Routine Immunization in the United States: An Update. … Safety of probiotics used to reduce risk and prevent or treat disease.

305. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
     January 01, 2007 - The second-generation sulfonylureas, which are used today, were Comparative Effectiveness and Safety … Do oral diabetes medications for the treatment of adults with type 2 diabetes differ in their safety … similar between metformin and other oral diabetes medications or placebo (8.4 vs. 9 cases per 100,000 patient-years … additional limitations that influenced their conclusions was their decision to include studies with diverse patient … similar between metformin and other oral diabetes medications or placebo (8.4 vs. 9 cases per 100,000 patient-years

306. S3 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s3.pdf
     October 01, 2007 - EDITORIAL The Comparative Effectiveness and Safety Emerging Methods Symposium A Tribute to Harry A. … knowledge about the development and application of methods pertaining to comparative effectiveness and safety … core material of standard clinical textbooks verbatim and could recite that material in the care of patients … mastered, but also had an ability to analyze and apply original research articles in the care of the patients … was the first person I encountered who masterfully demonstrated the application of these methods to patient

307. Research Protocol: Breast Reconstruction After Mastectomy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-reconstruction-mastectomy-protocol.pdf
     April 09, 2020 - U.S. were estimated for 2019.2 Surgery is a component of the standard treatment strategy for most patients … satisfaction and fewer complications in patients undergoing postmastectomy radiation therapy.26 But … FDA Update on the Safety of Silicone Gel-Filled Breast Implants. 2011. https://www.fda.gov/media/80685 … : FDA Safety Communication.; 2019. https://www.fda.gov/medical-devices/safety-communications/fda- requests-allergan-voluntarily-recall-natrelle-biocell-textured-breast-implants-and-tissue … your-rights-after-a-mastectomy.pdf https://www.fda.gov/media/80685/download https://www.fda.gov/medical-devices/safety-communications

308. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-bone-fracture_research-protocol.pdf
     May 14, 2010 - • Population(s): - For KQ1, all patients with, or at risk for, osteoporotic fractures (or who meet … - Subgroups of patients are considered in KQ2. … Available at: http://www.fda.gov/Safety/MedWatch/SafetyInformation/Safety- RelatedDrugLabelingChanges … /MedWatch/SafetyInformation/Safety-RelatedDrugLabelingChanges/ucm122109.htm� http://www.fda.gov/Safety … /MedWatch/SafetyInformation/Safety-RelatedDrugLabelingChanges/ucm122109.htm� http://www.fda.gov/Safety

309. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: Surveillance Report 2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-apps-a-e-surveillance-report-2-final_0_0.pdf
     March 01, 2022 - The pharmacokinetics, efficacy, and safety of a novel selective-dose cannabis inhaler in patients with … Efficacy, tolerability and safety of cannabinoids for management of pain in adult patients with multiple … Off- label use of cannabinoids efficacy and safety. … Safety and Efficacy of Medical Cannabis in Fibromyalgia. … Care of the Patient Using Cannabis.

310. Methods White Paper: Improving the Utility of Evidence Synthesis for Decision Makers in the Face of Insufficient Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/improving-utility-evidence-synthesis-white-paper.pdf
     April 01, 2021 - Patient safety in ambulatory settings. … VA National Center for Patient Safety . … Veterans Affairs (VA) managers and policymakers VA National Center for Patient Safety "improve … with STEMI Few trials followed patients long-term and lack of data regarding safety C-10 … Patient safety in ambulatory settings.

311. Methods Research Report: Testing a Machine Learning Tool for Facilitating Living Systematic Reviews of Chronic Pain Treatments (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-testing-machine-learning-tool-chronic-pain.pdf
     November 01, 2020 - A 1-year safety and efficacy study of duloxetine in patients with fibromyalgia. … Evaluation of efficacy and safety of gabapentin, duloxetine, and pregabalin in patients with painful … Comparative safety and tolerability of duloxetine vs. … in patients with moderate-to-severe chronic low back pain. … Safety and efficacy of tapentadol ER in patients with painful diabetic peripheral neuropathy: results

312. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
     June 16, 2010 - The 2006 CER revealed safety concerns for the erythropoietic stimulants as a class. … In an individual patient data meta-analysis of 13,933 patients in 53 trials treated with epoetin alfa … analyzed individual patient data from 2,122 patients in 6 trials receiving darbepoetin alpha finding … Study and Independent Patient Level Meta-Analysis Selection: Results from study- and patient-level meta-analysis … Erythropoietin or Darbepoetin for patients with cancer--meta-analysis based on individual patient data

313. Systematic Review on Treatments for Acute Pain: Surveillance Report 3 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-report-3-acute-pain.pdf
     June 01, 2022 - How do harms vary depending on: (1) patient demographics (e.g., age, gender); (2) patient medical or … How do harms vary depending on: (1) patient demographics (e.g., age, gender); (2) patient medical comorbidities … How do harms vary depending on: (1) patient demographics (e.g., age, gender); (2) patient medical and … safety and pain management: a systematic review and meta-analysis. … Effect of intensive patient education vs placebo patient education on outcomes in patients with acute

314. Crosscutting-Horizon-Scan-High-Impact-1406 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - Although propofol may be preferred for these reasons, its use is complicated by safety concerns. … of the controversy among clinical specialties (gastroenterology versus anesthesiology) about its safety … Patient acceptance of the technology might be low, although one expert thought that elderly patients … Clinicians can access objective, accurate, and timely data about patient adherence, to monitor patients … It may be solely age-based (i.e., patients 65 years and older) or also based on patient complaint and

315. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/treatment-resistant-depression_research-protocol.pdf
     December 09, 2009 - when the patient is treatment resistant. … For adults with treatment-resistant depression, do non-pharmacologic interventions differ in safety, … Comparators: ECT, rTMS, VNS, demonstrated effective psychotherapy • Outcomes for each question • Safety … KQ4 focuses on safety issues (adverse effects, adherence) with each of the interventions. … While the patient is ultimately the one to make the decision about whether to receive the non- pharmacologic

316. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/progestogens-preterm-birth_research-protocol.pdf
     June 01, 2010 - associated with preterm birth represent untold distress for families, as well as significant costs to patients … 17-OHP treatment regimen is relatively modest; one study estimates it to be about $400 per treated patient … Adherence is influenced by the timing, dose, route, and interval of the progestogen given, patient factors … Adverse events may occur at any point after the treatment is received, and are affected by patient factors … factors such as specialty, and health care system factors such as cost and availability, as well as patient

317. Ced-Appendix-3 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
     June 24, 2022 - NEST_data • Patient-centeredness: Patients are engaged in the RWD/RWE process and provide consent when … NAM 2018 Safety monitoring in real-world trials NAM 2018 Results more generalizable and relevant NAM … NAM2019 Questions to consider regarding participant safety and investigator control of treatments in … NAM2019 How much would the effectiveness or safety of the study treatment(s) vary among providers or … NAM2019 Is there some minimal or floor level of treatment quality necessary to assure participant safety

318. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/04_dementia_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - patient safety and care … safety and care. … A diagnosis could, however, help patients and families plan for the patient’s care and safety. … Furthermore, experts thought that the drug’s well-known safety profile and long history of use (in … AD patients.

319. Disposition of Comments_Technical Brief No. 40: Interventions To Decrease Hospital Length of Stay (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hospital-length-of-stay-disposition-comments_0.pdf
     September 20, 2021 - In addition, ICU LOS is often seen as an important measure (from a quality of care and safety standpoint … coaching), healthcare delivery processes, managed care and risk management, and hospital quality and safety … Ideally there would be more patient or family stakeholder KIs. … coaching), healthcare delivery processes, managed care and risk management, and hospital quality and safety … Presumably the patient level factors that drive prolonged length of hospital stay in patients with multi

320. Atrial-Fibrillation-Ablation Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_surveillance.pdf
     May 16, 2013 - What are the patient-level and intervention-level characteristics associated with RFA effect on short … Safety surveillance alerts (Cycle 2): No relevant safety alerts. 1st assessment conclusion (Cycle 1 … Safety surveillance alerts (Cycle 2): No relevant safety alerts. 1st assessment conclusion (Cycle 1 … Safety surveillance alerts (Cycle 2): No relevant safety alerts. 1st assessment conclusion (Cycle 1 … Safety surveillance alerts (Cycle 2): No relevant safety alerts. 1st assessment conclusion (Cycle 1