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effectivehealthcare.ahrq.gov/sites/default/files/related_files/diagnostic-error-executive-summary.pdf
August 01, 2023 - The causal and risk factor literature was strongest
for patient and illness characteristics and relatively … safety concern. … Diagnostic error in the emergency
department: learning from national patient
safety incident report … Improving Diagnostic
Quality and Safety Final Report. 2017. … BMJ quality & safety. 2018 Jul;27(7):567-
70. doi: 10.1136/bmjqs-2018-007945.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0122_06-29-2009.pdf
January 01, 2009 - Description
Nominator: Individual
Nomination
Summary:
The nominator is interested in the safety … This topic will move forward as a new systematic review that will address the safety, effectiveness … It may also address issues
around patient monitoring, nursing protocol, collaborative care, and potential
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effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1412.pdf
December 01, 2014 - Experts wanted to see additional clinical trial data assessing
baclofen’s long-term safety and efficacy … solution to a reference
product; a user experience study with adult and juvenile volunteers; and a safety … All adult volunteers, and 15 of 19 adolescent volunteers,
successfully used Evzio, removing the safety … to patients’ families that it be available for emergency use at home. … ,
and patients’ families, the experts concluded.
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effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1506.pdf
June 01, 2015 - Experts cited the cost, need for daily injections, and unknown long-term safety
profile as potential … Patients were reported to have generally tolerated the balloon
well, with one early removal for patient … .”38 However, two experts anticipated lower patient acceptance.37,42 One
clinical expert stated, “Patients … Perioperative safety in the longitudinal
assessment of bariatric surgery. … Safety of antiobesity drugs. Ther Adv Drug Saf.
2013;4(4):171-81.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0263_12-28-2007.pdf
January 01, 2007 - Results of Topic Selection Process & Next Steps
Recombinant human growth hormone in patients … What is the evidence for harms of rhGH in CF patients? … )
Cystic Fibrosis affects both children and adults, and its clinical course varies from patient … to patient. … how-are-research-topics-chosen/
Topic Number(s): 0003
Document Completion Date: 6-2-09
2
The safety
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/instrumental-variable-methods_research.pdf
April 01, 2010 - about the outcomes, clinical effectiveness, safety, and appropriateness of health care items and … Instrumental variable methods in comparative safety
and effectiveness research. … Similarly, one could assess safety in these same patients by
exploring the association between formulary … In some cases, the concept of a “marginal patient” may be problematic as individual
patients may be … Distance must also not be related to patient characteristics.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_disposition-comments.pdf
October 01, 2010 - Results pg 23 - patient level characteristics. … In
Key question 2 - patient level factors - age has very important
implications. … - The primary safety cohort for the study included 139 patients. … - Overall, the primary and secondary safety analyses performed to
date represent an excellent safety … In Key question 2 - patient
level factors - age has very important implications.
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effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1506.pdf
June 01, 2015 - abuse by increasing the
perceived safety of a harmful behavior. … Commercial clients pay
annual licensing fees for CaringTXT, prorated on projected patient populations … CaringTXT annual licenses cost about $12,000 to $18,000 for an average-sized university or
college client … Across all client types, patients pay for text messages only if the service is not included
in their … As of June 2015, CaringTXT was in use by clients including
the University of Pittsburgh and the Central
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - ability
to
improve
patient-‐reported
symptoms,
functional
capacity,
or
quality … (Low)
KQ3: For patients with RA, do drug therapies differ in harms, tolerability, patient adherence, … Conclusion
probably out of
date regarding
safety for TB
patients. … ability to improve patient-reported symptoms, functional capacity, or quality of life? … (Low)
KQ3: For patients with RA, do drug therapies differ in harms, tolerability, patient adherence,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - ability
to
improve
patient-‐reported
symptoms,
functional
capacity,
or
quality … (Low)
KQ3: For patients with RA, do drug therapies differ in harms, tolerability, patient adherence, … Conclusion
probably out of
date regarding
safety for TB
patients. … ability to improve patient-reported symptoms, functional capacity, or quality of life? … (Low)
KQ3: For patients with RA, do drug therapies differ in harms, tolerability, patient adherence,
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f-surv-report-3-acute-pain.xlsx
May 29, 2025 - Patient Masked? Reporting of Attrition, Crossovers, Adherence, and Contamination? … Yes No No No Yes No/No Yes Yes Yes Fair
Cooper, 2021 Yes Yes Yes Unclear Yes Yes Yes No/No Yes; for safety … Yes Poor
Ilyas, 2021 No (by birth year) No Yes Yes No No Yes No/No No Yes; excluded 44 randomized patients … No No Unclear/Yes No Yes; 17% Yes Poor
Rian, 2021 Yes Unclear Yes Yes Yes Yes Yes No/No No Yes; 13 patients
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f-surv-report-2-acute-pain.xlsx
May 29, 2025 - Patient Masked? Reporting of Attrition, Crossovers, Adherence, and Contamination? … Yes No No No Yes No/No Yes Yes Yes Fair
Cooper, 2021 Yes Yes Yes Unclear Yes Yes Yes No/No Yes; for safety … Yes Poor
Ilyas, 2021 No (by birth year) No Yes Yes No No Yes No/No No Yes; excluded 44 randomized patients … No No Unclear/Yes No Yes; 17% Yes Poor
Rian, 2021 Yes Unclear Yes Yes Yes Yes Yes No/No No Yes; 13 patients
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
August 05, 2010 - Evidence-based Practice Center Systematic Review Protocol
Project Title: Comparative Effectiveness and Safety … In addition,
efficacy and safety may vary for individual drugs within a class. … We will also
include studies that report safety in patients with rheumatoid arthritis or were taking … ; setting (primary care or referral); the number of patients randomized relative to
the number of patients … Comparative effectiveness
and safety of analgesics for osteoarthritis.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-200-post-acs-depression.pdf
November 01, 2017 - • To assess the comparative safety and
effectiveness of pharmacologic and
nonpharmacologic treatments … KQ 2: What are the comparative safety and
effectiveness of pharmacologic and nonpharmacologic
depression … instruments:a Beck Depression Inventory-II (BDI-II); Hospital Anxiety and Depression Scale (HADS); Patient … • One or two specific items from validated screening
scales (BDI-II, Patient Health Questionnaire … 4 studies that
examined the comparative safety and effectiveness of
pharmacologic and nonpharmacologic
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/registry-of-patient-registries_research-2012-2_1.pdf
January 01, 2012 - The DEcIDE
network assists health care providers, patients, and policymakers seeking unbiased information … about the outcomes, clinical effectiveness, safety, and appropriateness of health care items and
services … Stakeholders included representatives from eight major
groups: patients/consumers; physicians, hospitals … information within a distinct patient registry study type. … Stakeholders included representatives from eight major groups:
patients/consumers; physicians, hospitals
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/epc-making-sure-evidence-understood.pdf
July 01, 2020 - Department of Health and Human
Services that is charged with improving the quality, safety, efficiency … What information is needed to make better
recommendations to patients? … Consumers, patients,
caregivers, and patient
advocacy organizations
It is vital that research answer … with accurate, independent, scientifically rigorous information for
comparing the effectiveness and safety … Patient, Population or Problem:
◆ The “P” in PICO(TS) is a description of the patient(s) of interest
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_executive.pdf
January 01, 2014 - effectiveness and safety differ? … and safety differ? … and safety differ? … and
anticoagulant therapies in UA/NSTEMI patients, we
had to broaden our eligible patient population … acute coronary syndrome: a meta-analysis of
individual patient data.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_executive.pdf
January 01, 2010 - KQ2: What is the evidence for safety of SIT in patients
with allergic rhinoconjunctivitis and/or asthma … What is the evidence for safety
of subcutaneous immunotherapy in patients with
allergic rhinoconjunctivitis … What is the evidence for safety
of sublingual immunotherapy in patients with
allergic rhinoconjunctivitis … What is the evidence for
safety of subcutaneous versus sublingual
immunotherapy in patients with … help inform patients on the efficacy and safety
of allergen immunotherapy.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive-2016.pdf
January 01, 2016 - How do benefits or harms of contrast media differ by
patient characteristics (known risk factors such … definitive evidence
of a difference in CIN incidence between IOCM and
LOCM that varied according to patient … A prospective, double-blind,
randomized, controlled trial on the efficacy and cardiorenal safety
of … The relative renal safety of
iodixanol compared with low-osmolar contrast media: a meta-
analysis of … Effect of administration route on
the renal safety of contrast agents: a meta-analysis of randomized
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-update_research-protocol.pdf
May 07, 2010 - differ in safety, adverse events, tolerability, persistence, and adherence? … Specific patient subgroups evaluated
will be stratified by sex, comorbidities, concurrent medication … major cardiovascular events [myocardial infarction ,
stroke] and measures of quality of life)
o Safety … diabetes)
Adverse Events
•Weight gain
•Impaired renal function
•Angioedema
•Cough
•Hyperkalemia
Safety … The safety outcomes will be framed to help identify angioedema and hyperkalemia,
which are both adverse