-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-child-adolesc-mental-health-grand-rounds.pptx
May 22, 2025 - ; that all scientific research used in support or justification of a patient care recommendation will … The Patient-Centered Outcomes Research Institute® (PCORI®) funded the report. … The Patient-Centered Outcomes Research Institute® (PCORI®) funded the report. … family-expressed emotion or family criticism, familial hostility, or familial overinvolvement directed towards the patient … latency age and young adults, externalizing disorders, neurodiversity, diverse populations
Collect patient
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-256-telehealth-women-preventive-services-executive-summary.pdf
June 01, 2022 - depression, fear of partner, coercive control, self-
efficacy, post-traumatic stress disorder, and safety … For IPV interventions,
patients were slightly older (mean age of 33 years). … of
Evidence
Harms Interactive online tool Noninteractive online tool 1 RCT (231) No difference in patient … reported anxiety
using a tailored, online safety tool vs. a
static version. … marker for
publication bias) due to small numbers of trials and heterogeneity in study design
methods, patient
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-insulin_executive.pdf
September 01, 2008 - However,
the addition of insulin to treatment
Comparative Effectiveness, Safety, and
Indications of … A number of patient-related factors have been
identified that may help physicians to select patients … Insulin lispro 75/25 was associated with a higher rate of
overall hypoglycemia measured as episode/patient … Key Question 4: Effect of premixed insulin
analogues based on patient characteristics
Comparison of … injection patterns and glucose testing
depending on the type of medication regimen
prescribed, evaluating patient
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_executive.pdf
May 01, 2013 - The burden of VTE is higher among some patient
populations, including patients who have experienced … and safety of pharmacologic
strategies for VTE prevention in patients with liver disease. … effectiveness and safety of pharmacologic strategies among
patients with liver disease. … in the patient populations. … RCTs should evaluate the comparative effectiveness
and safety of LMWHs in obese patients.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia_executive.pdf
May 01, 2006 - What are the comparative efficacy and safety of
epoetin (alfa or beta) and darbepoetin?
2. … Are any patient characteristics at baseline or early
hematologic changes useful to select patients or … empirically evaluated to determine whether the
degree of change is perceptible and meaningful to
the patient … treated with epoetin; this prompted an FDA safety
review in May 2004 and revised product labeling to … Neither higher than recommended
target Hb nor any other single patient- or treatment-
related factor
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/angina-heart-attack-treatments_research-protocol.pdf
December 11, 2012 - effectiveness and safety differ? … and safety differ? … and safety differ? … acute coronary syndrome a
meta-analysis of individual patient data. … followed by an
infusion of 1.75
mg/kg/hr (if CrCl< 30
ml/min reduce
infusion to 1.0
mg/kg/hr, if patient
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease_research-protocol.pdf
September 01, 2010 - Over time, 73% of patients will have a
relapsing and remitting course, while only 10% of patients will … Our proposal will address these aims, as well as the safety and patient-reported
outcomes representing … We aim to compare the effectiveness, safety and patient-reported outcomes
representing quality of life … The patient-reported outcomes will also help patients and caregivers to take into
consideration the … Objectives
We aim to compare the effectiveness, safety and patient-reported measures of individual
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0623-140828.pdf
April 25, 2014 - Individual
Nomination The topic was nominated by an individual who is specifically interested in the safety … ART)
Outcome(s): Conception, pregnancy, and safety and efficacy
Key Questions What are the best options … for fertility treatment, in terms of safety and effectiveness? … mental health of
women and their partners, making the selection of appropriate treatment critical.
§ Patients … clear understanding of the comparative effectiveness of available
treatment options, especially as patients
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0658-140831.pdf
July 19, 2014 - Topic Description
Nominator(s): Individual
Nomination The nominator is a patient with diabetic … The nominator
expresses an interest both in the improvement of symptoms for patients suffering from … diabetic peripheral neuropathy and in the prevention of the condition or its progression
among patients … What is the comparative safety and effectiveness of treatment options to delay or
from Nominator: reverse … What is the comparative safety and effectiveness of treatment options to improve
the symptoms of diabetic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_surveillance.pdf
August 01, 2012 - for Updating Systematic Reviews for the EHC Program
CER # 20:
Comparative effectiveness and safety … Comparative effectiveness and safety of
radiotherapy treatments for head and neck
cancer. … A
dosimetric correlation of radiation dose and
early grade 3 dysphagia in oropharyngeal
cancer patients … A
matched cohort comparison of head and
neck squamous cell carcinoma patients
treated with intensity … Multivariate analysis of quality of life
outcome for nasopharyngeal carcinoma
patients after treatment
-
effectivehealthcare.ahrq.gov/sites/default/files/cardiovascular-horizon-scan-high-impact-1412.pdf
December 01, 2014 - However, some noted insufficient information regarding long-term safety and
efficacy. … ; a long-term patient registry to determine long-
term safety; and an enhanced pharmacovigilance program … could affect physician
and patient acceptance. … Efficacy and safety of a microsomal triglyceride
transfer protein inhibitor in patients with
homozygous … Another trick to improve
the safety of transseptal puncture.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-centered-medical-home_research-protocol.pdf
February 23, 2012 - as a way of improving patient experiences,
outcomes, safety, and system efficiency.10-12 It is based … Intermediate patient outcomes (e.g., change in HbA1c for diabetic patients).
b. … A systems-based approach to quality, safety, and delivery of evidence-based care. … Intermediate patient outcomes (e.g., change in HbA1c for diabetic
patients).
ii. … care, superb access to care, and a systems-
based approach to quality and safety.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
August 01, 2013 - The number of patients included in studies ranged
from fewer than 100 to 170,291, with overlap in patient … The number of patients included in studies ranged
from fewer than 600 to 170,291, with overlap in patient … Warfarin
Ischemic stroke 1 (707) SOE = Low
9 LAA patients (1.3 events per 100 patient-years) and 6 … warfarin patients (1.6 events per 100 patient-years) had
ischemic stroke, demonstrating no difference … Given
variability in patient populations, concomitant therapies,
and underlying patient care, cross-trial
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
January 01, 2023 - (e.g., patient engagement) … Study Design
• Longitudinal explanatory and pragmatic trials to
evaluate effectiveness and safety … Design
• Trials with sufficient sample size designed to
evaluate differential effectiveness and safety … • Studies with sufficient size to evaluate
differential effectiveness and safety of
treatments in … products/acute-pain-ems/research
Purpose
This report, nominated by the National Highway Traffic Safety
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
April 01, 2012 - Finally,
very little is known about the benefits or risks of these
drugs in different patient subgroups … KQ 2: For patients with PsA, do drug therapies differ
in their ability to improve patient-reported symptoms … KQ 3: For patients with PsA, do drug therapies differ in
harms, tolerability, patient adherence, or … eligibility (inclusion and exclusion) criteria were
designed with respect to study design or duration, patient … Safety and efficacy
of adalimumab in treatment of patients with psoriatic arthritis who
had failed
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-year-in-review-2023.pdf
January 01, 2023 - effectivehealthcare.ahrq.gov/products/postpartum-care-one-year/research
https://effectivehealthcare.ahrq.gov/products/patient-safety-telehealth … /research
https://effectivehealthcare.ahrq.gov/products/patient-safety-telehealth/research
https://effectivehealthcare.ahrq.gov … Making Healthcare Safer IV: Final Report on Prioritization of Patient Safety Practices for a New
Rapid … effectivehealthcare.ahrq.gov/products/telehealth/research-report
https://effectivehealthcare.ahrq.gov/products/prioritization-patient-safety-practices … https://effectivehealthcare.ahrq.gov/products/prioritization-patient-safety-practices
19
Table E3
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_disposition-comments.pdf
February 25, 2014 - centered outcomes, and observational studies along with RCT
for safety. … All patients in global safety summary
were Crohn’s Disease patients. … Please consider inclusion of this safety data. … According to our analytic
framework, patient-reported
outcomes are relevant. … questions
in terms of final patient important outcomes.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0496_12-30-2011.pdf
January 01, 2011 - Nominator: Individual
Nomination
Summary:
The nominator questions the comparative renal safety … Staff-Generated PICO
Population(s): Patients undergoing interventional or diagnostic procedures requiring … the use of contrast media; subgroups of interest include patients with renal dysfunction
or diabetes … What is the comparative renal safety of different contrast media used in radiographic
imaging? … In addition, with the aging population, more elderly patients are undergoing contrast-
enhanced imaging
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_executive.pdf
June 01, 2013 - Do the comparative safety and
effectiveness of these therapies differ among specific
patient subgroups … Do the comparative safety and
effectiveness of these therapies differ among specific
patient subgroups … Do the comparative safety and
effectiveness of these therapies differ among specific
patient subgroups … Do the comparative safety
and effectiveness of these therapies differ among
specific patient subgroups … Do the comparative safety and effectiveness of these
therapies differ among specific patient subgroups
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
December 01, 2010 - • Patient insight into illness.
• Health-related quality of life. … • Patient satisfaction.
• Patient-reported outcomes. … psychosis
Loxapine Approved 1975 Schizophrenia
Adults
Safety and effectiveness in pediatric … Perphenazine Approved 1965 Schizophrenia
Adults
Safety and effectiveness in pediatric
patients … Adults
Pediatric use: safety & effectiveness not
established in patients <18 yrs
1. agranulocytosis