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effectivehealthcare.ahrq.gov/sites/default/files/pdf/off-label-use-research-priorities_research.pdf
May 01, 2009 - ope of P res c ribing P rac tic es E xamined
To capture recent prescribing patterns, we analyzed 30 months … Our assessment has extended past studies by
examining drug characteristics that can impact the level … While past research
has highlighted the substantial frequency of off-label use without good evidence … Such research would
initially take the form of meta-analyses to accumulate and assess past clinical … f The Market Entry index value is coded as 1 for drugs that entered within the past 3 years, 0.5 for
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-disposition-comments.pdf
July 31, 2024 - the authors’ responses to the comments are posted
for public viewing on the website approximately 3 months … Reviewer
#1
Aimee Shelton
Nutrition
Counselor,
Emergence
Functional
Nutrition
Alvin, TX
General Past
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis_hi_impact.pdf
January 01, 2014 - Belimumab
Key facts: No new treatments had been developed or approved for SLE in the past 40 years … No incidence of gout flares was reported in the 2-week arm after 5-months. … declining at 12 months followup (p = 0.02). … At 6 months, all placebo-assigned patients were advanced to tofacitinib. … Placebo patients were given
tofacitinib at 3 months.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-fracture-prevention-evidence-summary.pdf
April 01, 2019 - In short-term (18 to 36 months) randomized
controlled trials (RCTs) for osteoporosis
treatment, bisphosphonates … Most
observational studies presumed participants had
osteoporosis because of past fracture or use of … Evidence*
(Justification)
Estrogen vs. placebo
1 RCT19
7.1 yr (mean)
10,739 PM women with
past … Hip Lower risk: HR=0.65 [0.45,
0.94]; ARR= -0.5 [-0.9, -0.08]
Moderate (IM)
3,816 PM women with
past … hysterectomy and past
clinical fracture
CF Lower risk: HR=0.73 [0.62,
0.86]; ARR= -5 [-7, -2]
Low
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_research-protocol.pdf
October 01, 2013 - We briefly reviewed the seven meta-analyses published within the last 12 months on
CIN and summarized … Development of CKD, including end stage renal disease (ESRD)
● Rate of conversion to CKD at 3 and 6 months … transplant)
c) Other clinical outcomes
● Cardiac outcomes
● Mortality in hospital or at 3 or 6 months … The Trans-catheter Cardiovascular Therapeutics
conference, Radiological Society of North America (past … and upcoming meetings), and
Society of Abdominal Radiology (past and upcoming meetings).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_research-protocol.pdf
September 20, 2013 - will develop breast cancer during their lifetime, and an
estimated 2.7 million women had a current or past … women aged ≥40 years and
79.7% of women aged 50 to 74 years reported having a mammogram within the past … either open surgical biopsy
or followup by clinical examination and/or mammography for at least 6 months … are:
o Open surgical biopsy,
o Followup by clinical examination and/or mammography for at least 6 months … biopsy samples
● Timing
Duration of clinical and/or mammographic followup must be at least 6 months
-
effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1506.pdf
November 01, 2016 - depending on expert comments received on interventions issued for
comment during the preceding 6 months … In the past 12–15 months, even fewer topics have met criteria for tracking because so few of the
leads … In preliminary results derived from the first 6 months of study, a manufacturer’s press
release reported … the following:4
Results from the trial show that after six months of treatment, both doses of elagolix
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effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1512.pdf
November 01, 2016 - depending on expert comments received on interventions issued for
comment during the preceding 6 months … In the past 12–15 months, even fewer topics have met criteria for tracking because so few of the
leads … In preliminary results derived from the first 6 months of study, a
manufacturer’s press release reported … the following:4
Results from the trial show that after six months of treatment, both doses of elagolix
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ear-infection_research-protocol.pdf
August 07, 2012 - at least one episode of OME by age 10, with the
majority of cases occurring between the ages of 6 months … and 4 years.2, 3 Many episodes of OME resolve
spontaneously within 3 months, but 30 to 40 percent of … with no differences seen at 12 and 18 months. … T: Short-term studies looking at outcomes from 0–3 months postintervention. … Longer term studies looking at outcomes past 3 months and into adolescence or adulthood.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-nerve-block-protocol.pdf
November 18, 2023 - 72 hours of surgery or during the inpatient stay),
subacute (discharge up to and including three months … postoperatively), and chronic
(greater than 3 and up through 12 months postoperatively). … subdivided into
72 hours or less; >72 hours or discharge up to
<30 days; 30 days up to ≤3 months … Post-operative period 3-12 months
Other timing
Setting Perioperative (inpatient or outpatient … We will then not screen citations remaining past a 95 percent recall rate
of citations eligible for
-
effectivehealthcare.ahrq.gov/sites/default/files/decide16final-mortality-risk-in-copd-pts-using-theophylline.pdf
December 01, 2009 - participated in chronic obstructive
pulmonary disease advisory boards for Astra Zeneca and Novartis in the past … For each person in the analysis, medication exposure during the six months preceding
each day during … We selected six months as our time frame for
exposure measurement because we did not want associations … Additionally, six months ensures sufficient time for chronic exposure and includes two
dispensings of … The rates of use were approximately 70% or higher over the first 18 months
and then decreased in each
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-management_research.pdf
December 01, 2009 - participated in chronic obstructive
pulmonary disease advisory boards for Astra Zeneca and Novartis in the past … For each person in the analysis, medication exposure during the six months preceding
each day during … We selected six months as our time frame for
exposure measurement because we did not want associations … Additionally, six months ensures sufficient time for chronic exposure and includes two
dispensings of … The rates of use were approximately 70% or higher over the first 18 months
and then decreased in each
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prosthesis_research-protocol.pdf
March 16, 2017 - prosthetist and treating physician, considering factors including, but
not limited to, the beneficiary’s past … At 6 months, 1 year, and 5 years after receipt of a LLP, (accounting for
intervening mortality, subsequent … The assessment technique may include both past
history and markers of current status. … Predictor tool: A tool used or designed to predict future function based on a patient’s
past history … The disposition of comments for systematic
reviews and technical briefs will be published three months
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adults-trauma-interventions_research-protocol.pdf
November 08, 2012 - efficacy)
• Timing
– Intervention must be administered any time ranging from immediately to 3
months … • Can be used to make a current or lifetime diagnosis of PTSD or to assess
symptoms over the past … • Can be used to make a current or lifetime diagnosis of PTSD or to assess
symptoms over the past … • Assesses frequency of PTSD symptoms in the past month and self-ratings of
impairment across 9 areas … • Interviewees are asked about symptoms they have experienced in the past 2
weeks.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/undescended-testicle_research-protocol.pdf
September 02, 2011 - uncertainty, there is growing clinical consensus that orchiopexy should be
performed between 6 and 24 months … conditions, such as
infertility or testicular cancer, that work backwards to
determine whether past … cause will not be included due to the inherent difficulty in
accurately capturing information on past … the peer review comments are documented and will, for
CERs and Technical briefs, be published three months
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-anticholinergic-medicines_research.pdf
December 01, 2009 - Lee
has received past research grants from GlaxoSmithKline. Dr. … Lee has participated in past
advisory boards for AstraZeneca and Novartis. … exacerbation that resulted in a
hospitalization or at least two outpatient exacerbations in the last 12 months … Covariates
We defined covariates from the 12 months preceding the index date. … baseline and had a slightly larger percentage with 3 or
more outpatient visits in the preceding 12 months
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-rehospitalization_research.pdf
November 01, 2007 - Crude rates of readmissions for heart failure were high overall during the first 12 months
post-discharge … cardiovascular conditions, the burden of heart failure
has continued to increase substantially over the past … Crude rates (per 100 person-years) of rehospitalization
for heart failure during the first 12 months … prior to and 12 months after the index hospitalization.
4.1. … (30
days per month) before the index admission date and for at least 12 months (30 days per
month)
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
February 15, 2017 - Population(s):
o Adults who received a criterion-based diagnosis of depression and are
within 3 months … of hospitalization for an acute ACS event
§ Beyond 3 months of hospitalization for an acute ACS event … KQ 2: Adults who received a criterion-based diagnosis of
depression and are within 3 months of an acute … Past Year Mental Disorders among Adults in the
United States: Results from the 2008–2012 Mental Health … The disposition of comments for systematic
reviews and technical briefs will be published three months
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/case-management_disposition-comments.pdf
January 01, 2013 - responses to the comments are posted for
public viewing on the EHC Program Web site approximately 3 months … Coleman which this review excluded
are only two examples of important research
conducted over the past
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_disposition-comments.pdf
December 11, 2012 - responses to the comments are posted for
public viewing on the EHC Program Web site approximately 3 months … We know that the data show it is very rare for
spontaneous testicular decent after 9 months. … Watchful waiting is only appropriate during
a certain time interval-during the first 9 months of life … We have added the phrase, "most occurring in
the first three months." … to
compare with the more recent literature, as surgical standard of practice
has changed over the past