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  1. www.uspreventiveservicestaskforce.org/home/getfilebytoken/gXnmnkofo8FxoLnCmXJDjb
    October 01, 2009 - An- other study, from the Rotterdam Coronary Calcification Study, used self-selected participants who … The predictive value of a high CAC score was inconsistent; for example, participants with a Framingham … risk score of 11% to 15% and participants with a risk score of 16% to 20% had the same baseline risk … The CAC score also seemed to be imprecise; among participants who had a high CAC score, those with a … The Women’s Antioxidant Cardiovascular Study: design and baseline char- acteristics of participants.
  2. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/v1-breast-cancer-medications-for-risk-reduction--s
    May 06, 2002 - Participants were stratified by age (35-49, 50-59, and > 60) and estimated 5-year risk of breast cancer … Participants were randomly assigned to raloxifene or placebo. … BCPT participants in the tamoxifen arm had a 2.53 (95 percent CI, 1.35-4.97) times greater risk of developing … Investigators also followed participants for the occurrence of thromboembolic events ( Table 3 ). … In summary, several features of the European studies and their participants likely reduced the observed
  3. www.uspreventiveservicestaskforce.org/home/getfilebytoken/-hnLT26c2NHs6thK9yznPF
    July 01, 2002 - Participants were stratified by age (35- 49, 50-59, and >60) and estimated 5-year risk of breast cancer … Participants were randomly assigned to raloxifene or placebo. … BCPT participants in the tamoxifen arm had a 2.53 (95% CI, 1.35-4.97) times greater risk of developing … Investigators also followed participants for the occurrence of thromboembolic events (Table 3). … In summary, several features of the European studies and their participants likely reduced the observed
  4. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-cancer-medications-for-risk-reduction-2002
    May 06, 2002 - Participants were stratified by age (35-49, 50-59, and > 60) and estimated 5-year risk of breast cancer … Participants were randomly assigned to raloxifene or placebo. … BCPT participants in the tamoxifen arm had a 2.53 (95 percent CI, 1.35-4.97) times greater risk of developing … Investigators also followed participants for the occurrence of thromboembolic events ( Table 3 ). … In summary, several features of the European studies and their participants likely reduced the observed
  5. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-statins/statin-use-in-adults-preventive-medication
    November 13, 2016 - Results: Nineteen trials (n = 71,344 participants [range, 95-17,802]; mean age, 51-66 years) compared … Studies were limited to those in which fewer than 10% of the participants had prior CVD events to include … (total sample, 71,344 participants). … b More than 10% of participants with history of CVD at baseline. … Consistent High applicability to US primary care settings All studies enrolled participants with
  6. www.uspreventiveservicestaskforce.org/home/getfilebytoken/_9KLmyQyMnoE3agQJsgNE-
    November 01, 2011 - Data Synthesis: On the basis of 4 fair- to good-quality studies (141 566 participants), LBC had equivalent … On the basis of 2 fair- to good-quality randomized, controlled trials (RCTs) (120 533 participants), … ) (46–49) and 4 diagnos- tic accuracy studies (comprising 21 739 participants) (36, 41–43). … Two smaller studies (36, 43), comprising 3852 participants, reported positive cotesting Table 2. … A large observa- tional study (61) conducted in the United States (331 818 participants) reported high
  7. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-statins/statin-use-in-adults-preventive-medication-november-2016
    November 13, 2016 - Results: Nineteen trials (n = 71,344 participants [range, 95-17,802]; mean age, 51-66 years) compared … Studies were limited to those in which fewer than 10% of the participants had prior CVD events to include … (total sample, 71,344 participants). … b More than 10% of participants with history of CVD at baseline. … Consistent High applicability to US primary care settings All studies enrolled participants with
  8. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary17/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing-2013
    December 15, 2013 - Data Extraction: Individual investigators extracted data on participants, study design, analysis, follow-up … Mutation carriers had more subjective sleep problems than noncarriers and age-matched control participants … Adverse effects for trial participants are relevant to mutation carriers. … Well-designed investigations using standardized measures and enrolling participants that reflect the … Study, Year (Reference) Participants, n Design Genetic Counseling Provider Setting Measure
  9. www.uspreventiveservicestaskforce.org/uspstf/document/published-comment-and-response-do-lipid-lowering-agents-provide-a-greater-reduction-in-cardiovascular-events-among-patients-with-diabetes/diabetes-mellitus-type-2-in-adults-screening
    November 15, 2008 - For example, in the Heart Protection Study, the absolute reduction in coronary events for participants
  10. www.uspreventiveservicestaskforce.org/uspstf/document/published-comment-and-response-do-lipid-lowering-agents-provide-a-greater-reduction-in-cardiovascular-events-among-patients-with-diabetes/diabetes-mellitus-type-2-in-adults-screening-2008
    November 15, 2008 - For example, in the Heart Protection Study, the absolute reduction in coronary events for participants
  11. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary20/suicide-risk-in-adolescents-adults-and-older-adults-screening
    April 15, 2013 - Most trials targeted participants who had an emergency department visit or inpatient stay related to … This fairly large trial ( n = 843) sent participants 24 letters over 5 years expressing concern and … Retention in this trial was low (only 31% of participants remained at the final 13-month follow-up). … who attempted suicide at follow-up (0.5% to 28% of control participants). … † Participants were parasuicidal. ‡ Median number of self-mutilation acts.
  12. www.uspreventiveservicestaskforce.org/home/getfilebytoken/vxPM4Bo9RXZGUDH6MWnDht
    May 01, 2013 - Most trials targeted participants who had an emer- gency department visit or inpatient stay related to … Retention in this trial was low (only 31% of participants remained at the final 13- month follow-up). … Participants receiving lithium were more likely to withdraw from the study because of adverse effects … who attempted suicide at follow-up (0.5% to 28% of control participants). … For example, if all participants in all psychotherapy trials that reported suicide deaths were treated
  13. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/lung-cancer-screening1
    May 03, 2018 - Are the participants of lung cancer screening trials (e.g., NLST) who reported a reduction in all-cause … in the United States (based on USPSTF recommendations or NLST criteria) compare with those of NLST participants
  14. www.uspreventiveservicestaskforce.org/home/getfilebytoken/xBhJwGtUHqmEvPg_gKk4nw
    January 01, 2001 - § Well-designed studies should include, but are not limited to, nonbiased selection of screening participants … and ethnicity, gender, rurality [and/or geographically underserved areas]) and settings of enrolled participants
  15. www.uspreventiveservicestaskforce.org/home/getfilebytoken/XU6eC2BfW2jbZGN4UCd94s
    June 01, 2012 - Benefits and Harms The Task Force examined changes in eating and physical activity behaviors that participants … The Task Force also studied the effects of these programs on participants’ weight, blood pressure, and
  16. www.uspreventiveservicestaskforce.org/home/getfilebytoken/WGyw9FcXJDcAM_Uj_uwPBW
    January 01, 2001 - § Well-designed studies should include, but are not limited to, nonbiased selection of screening participants … and ethnicity, gender, rurality [and/or geographically underserved areas]) and settings of enrolled participants
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/tpsQcTR2sDok_YELXgBHFb
    July 23, 2024 - of composite outcomes with potentially higher event rates.”1 “The process of identification of participants
  18. www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
    September 28, 2021 - Fifteen smaller trials were conducted in various developed countries. 1 , 8 , 16-18 In general, trial participants … Nulliparous and multiparous participants were combined in most trials. … mg/d, with most trials using 60 mg/d (6 RCTs) or 100 mg/d (8 RCTs). 1 Included trials of selected participants … Studies of average-risk pregnant individuals (5 trials) were included with trials of participants at … increased risk (16 trials). 1 All trials were placebo-controlled, except 1 study in which participants
  19. www.uspreventiveservicestaskforce.org/uspstf/recommendation/healthy-weight-and-weight-gain-during-pregnancy-behavioral-counseling-interventions
    May 25, 2021 - computer, internet, or telephone). 1 Effective behavioral counseling interventions often referred participantsParticipants were counseled on healthy diet and exercise through individual or group education sessions … Study sample sizes ranged from 50 to 2261; the total number of participants in all included studies was … BMI inclusion criteria varied across the trials; there were participants with overweight or obesity ( … Intervention participants generally used free weights, resistance equipment, or both.
  20. www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/prevention-human-immunodeficiency-virus-hiv-infection-prep
    December 13, 2022 - All trials included behavioral and adherence counseling, and most provided condoms to all trial participants … Among U.S. participants (37% of total participants), 50% were Black. … Participants were female (sex assigned at birth), were ages 18 to 45 years (median, 25 years), reported … 0.97 to 1.34]), 15 though all trials except for one were blinded, which could affect risk of STIs if participants … In five observational studies of PrEP with TDF-FTC, two of 1,936 participants were diagnosed with an

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