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  1. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cardiovascular/aspirin-to-prevent-cardiovascular-disease-and-cancer
    April 11, 2016 - ; trials ranged from 1276 to 39,876 participants 24 , 30-39 ( Appendix Table ). … was 55 to 70.5 years, and the oldest participants recruited were aged 84 and 85 years. 30 , 35 , 39 … Seven trials examined aspirin's total MI effect in participants with diabetes: 3 31 , 32 , 35 were … , 0.88 [CI, 0.67 to 1.15], and nondiabetic participants, 0.87 [CI, 0.79 to 0.96]). … Three trials 31 , 32 , 35 conducted exclusively in participants with diabetes showed no all-cause
  2. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cardiovascular/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
    April 11, 2016 - ; trials ranged from 1276 to 39,876 participants 24 , 30-39 ( Appendix Table ). … was 55 to 70.5 years, and the oldest participants recruited were aged 84 and 85 years. 30 , 35 , 39 … Seven trials examined aspirin's total MI effect in participants with diabetes: 3 31 , 32 , 35 were … , 0.88 [CI, 0.67 to 1.15], and nondiabetic participants, 0.87 [CI, 0.79 to 0.96]). … Three trials 31 , 32 , 35 conducted exclusively in participants with diabetes showed no all-cause
  3. www.uspreventiveservicestaskforce.org/home/getfilebytoken/teeHcmNgvNBSj4-E9SN5QK
    February 01, 2005 - The 4 trials included more than 125 000 total participants. … All control group participants were followed passively and without contact. … Across the 4 trials, 63% to 80% of invited participants attended ultrasound scanning. … Participants with normal-size aortas (<3.0 cm) on the initial scan received no further follow-up. … United Kingdom Small Aneurysm Trial Participants.
  4. www.uspreventiveservicestaskforce.org/uspstf/recommendation/screening-eating-disorders-adolescents-adults
    March 15, 2022 - Sample sizes ranged from 51 to 1541 participants (median, 341). 1 , 27 Most studies assessed the SCOFF … No trials were found that enrolled participants who were screen-detected in primary care. … Study participants were either referred or recruited to treatment. … Many studies enrolled participants via advertisements for interventions for binge eating and obesity. … The majority of the trials enrolled mostly female participants and populations with binge eating disorder
  5. www.uspreventiveservicestaskforce.org/home/getfilebytoken/d8DVjQhw6JgjWaBtED97s6
    June 05, 2024 - KQ4 Both Health equity Longitudinal followup (5–10 years) of study participants from behavioral intervention … a higher prevalence of high BMI (e.g., Hispanic/Latino, Long-term psychosocial outcomes in participants … clinical trials with longitudinal followup of weight loss maintenance; longitudinal followup of participants
  6. www.uspreventiveservicestaskforce.org/home/getfilebytoken/RRALFxUMfP7TXazQY32ZbG
    June 12, 2018 - exercise ECG (Table 2).12-16 All participants were from cardiology or prevention centers in hospitals … Of those 20 participants, 17 underwent coronary angiography (6.5% of the 262 in the screened group). … Adults without a history of CVD; mean age of participants 50-58 y; range of females was 0%-38%; race/ … ; range of nonwhite participants in those who reported race/ethnicity (6 studies) was 9%-41%. … Low for improvement Reclassification 7 studies, 59 123 participants; 3 studies FRS or PCE + multiple
  7. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Q6R-Lv4bzc_Tc-T9X-R2ZC
    January 09, 2018 - Two cohort studies (n = 339) on long-term outcomes found that braced participants reported more negative … treatment experience and body appearance compared with surgically treated or untreated participants. … and 58% of untreated participants (the unadjusted odds ratio for a successful outcome was 4.11 [95% … , 27.7° in braced participants; P = .07). … compared with zero reports in the 96 observed participants.
  8. www.uspreventiveservicestaskforce.org/home/getfilebytoken/ph_fauqHQjmrSqPAWKrARA
    September 28, 2021 - A total of 23 randomized clinical trials (RCTs) (N = 26 952) were included; 18 were conducted among participants … The incidence of preeclampsia among the trials of participants at increased risk ranged from 4% to 30% … For comparisons of effects by population risk of preeclampsia, studies in which more than 12% of participantsParticipants withdrew from treatment for a variety of rea- sons. … It was common for participants to withdraw due to non- medical reasons, including relocating, changing
  9. www.uspreventiveservicestaskforce.org/home/getfilebytoken/UXw277rnvJ8e_Dfsh4V3K3
    July 26, 2022 - Pooled Results of Behavioral Outcomes Outcome Effect size (95% CI) No. of RCTs (No. of participants … Twenty-four trials reported the proportion of participants meeting recommended levels of physical activity … and 25.4% to 71% of control group participants), and none reported rates of any adverse events to be … Very few trials reported the underlying CVD risk of participants at baseline (ie, the proportion of participants … This variation likely reflects that even within studies, some participants can achieve greater change
  10. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/falls-prevention-in-older-adults-interventions
    October 22, 2015 - How do included trials categorize participants as “high risk” for falls? … Includes older adults who are at average and high risk for falls; participants may be recruited from … Risk categorization will be determined based on the studies’ recruitment strategies, participants’ baseline
  11. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/falls-prevention-in-older-adults-interventions-2018
    October 22, 2015 - How do included trials categorize participants as “high risk” for falls? … Includes older adults who are at average and high risk for falls; participants may be recruited from … Risk categorization will be determined based on the studies’ recruitment strategies, participants’ baseline
  12. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/osteoporosis-screening
    January 14, 2025 - ) and major osteoporotic fracture (pooled RR, 0.94 [95% CI, 0.88-0.99]; 3 RCTs; 42,009 participants) … Corresponding absolute risk differences were 5 to 6 fewer fractures per 1000 participants screened. … Compared with placebo, bisphosphonates (pooled RR, 0.67 [95% CI, 0.45-1.00]; 6 RCTs; 12,055 participants … ) and denosumab (RR, 0.60 [95% CI, 0.37-0.97] from the largest RCT [7808 participants]) were associated … The authors also reported a per-protocol analysis for 18,605 participants.
  13. www.uspreventiveservicestaskforce.org/home/getfilebytoken/HMSNGkJatRuN5VoVWfbuFL
    March 01, 2022 - reported 12 months or longer.1,38 Most trials (73 trials) included men and women.1,38 The mean age of participants … ranged widely, from 18.5 to 79.5 years.1,38 The mean BMI of trial participants across stud- ies was … counseling interventions on diet, physical activity, or seden- tary health behaviors.1,38 On average, participants … recommendations after 6 to 12 months (pooled odds ratio, 1.41 [95% CI, 1.18 to 1.67]) compared with participants … in the control group.1,38 Participants of healthy diet in- terventions (45 trials) increased fruit and
  14. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/falls-prevention-in-older-adults-interventions
    April 17, 2018 - Trials solely recruiting participants with specific medical diagnoses (eg, neurologic diagnoses such … Trials solely recruiting participants with vitamin D insufficiency or deficiency, as determined by the … The majority of trials were conducted in Europe, with number of trial participants ranging from 55 to … The mean age ranged from 68 to 88 years, and in all but 1 trial the majority or all participants were … High-Risk Definition Twelve trials recruited participants at high risk for falls, 42-44 , 46 , 48 ,
  15. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/falls-prevention-in-older-adults-interventions-2018
    April 17, 2018 - Trials solely recruiting participants with specific medical diagnoses (eg, neurologic diagnoses such … Trials solely recruiting participants with vitamin D insufficiency or deficiency, as determined by the … The majority of trials were conducted in Europe, with number of trial participants ranging from 55 to … The mean age ranged from 68 to 88 years, and in all but 1 trial the majority or all participants were … High-Risk Definition Twelve trials recruited participants at high risk for falls, 42-44 , 46 , 48 ,
  16. www.uspreventiveservicestaskforce.org/uspstf/document/screening-for-hiv-in-pregnant-women-evidence-summary/human-immunodeficiency-virus-hiv-infection-screening-2013
    November 15, 2012 - The large (7753 participants), prospective, fair-quality MIRIAD (Mother-Infant Rapid Intervention At … The largest cohort study (involving 7344 participants), based on U.S. surveillance data from 1999 to … One trial (609 participants) found high rates of mother-to-child transmission with ultrashort-course … Sample sizes ranged from 57 to 8793 participants. … Seven cohort studies (352 to 8192 participants) published since the 2005 USPSTF review found no clear
  17. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/unhealthy-alcohol-use-adolescents-adults-behavioral-counseling-interventions
    February 01, 2024 - Adolescents and adults (age ≥12 years), including individuals who are pregnant KQs 1–3: Studies whose participants … not meet criteria for severe alcohol use disorder or alcohol dependence Studies in which >50% of participants … Screening to identify eligible participants must take place in broad-based, general settings comparable
  18. www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/high-body-mass-index-children-adolescents-interventions
    December 12, 2023 - various specialty outpatient clinics or research facilities). 1 Most trials (41/50) included study participants … children. 1 Most trials did not report on race or ethnicity or included predominantly white study participants … . 1 There was limited inclusion of Native American/Alaska Native or Asian participants. … In the included trials, 31% to 93% of participants completed all the sessions. … sites in the United States; the remaining trial was conducted in Germany. 1 The majority of study participants
  19. www.uspreventiveservicestaskforce.org/uspstf/recommendation/breastfeeding-primary-care-interventions
    April 11, 2025 - The participants in the majority of the US-based studies (24/33) were predominantly Black and/or Hispanic … , although 12 interventions included group sessions with other participants. 29 , 30 Trials varied widely … Generally, the number of participants analyzed for each of these outcomes was much smaller, making it … intervention, although 1 trial reported greater feelings of anxiety and decreased confidence among participants … Twenty-two trials (n = 13,815) reported that participants in the intervention group experienced fewer
  20. www.uspreventiveservicestaskforce.org/uspstf/recommendation/coronary-heart-disease-screening-using-non-traditional-risk-factors
    October 15, 2009 - risk score of 11% to 15% and participants with a risk score of 16% to 20% had the same baseline risk … The CAC score also seemed to be imprecise; among participants who had a high CAC score, those with a … Finally, participants were potentially self-selected. … When all good- or fair-quality studies in participants without previous coronary disease were pooled, … The Women's Antioxidant Cardiovascular Study: design and baseline characteristics of participants.

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